Author results

5WL2
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VH1-69 GERMLINE ANTIBODY WITH CDR H3 SEQUENCE OF CR9114
分子名称:Heavy chain of VH1-69 germline antibody with CDR H3 sequence of CR9114, Germline-reverted light chain of CR9114
著者Wilson, I.A., Lang, S.
登録日2017-07-25
公開日2018-08-01
最終更新日2019-04-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Anti-idiotypic antibody K1-18 engages VH1-69 precursor and affinity-matured, anti-stem antibodies through mimicry of the HA stem.
To Be Published
6OCB
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CRYSTAL STRUCTURE OF FLUA-20 FAB IN COMPLEX WITH THE HEAD DOMAIN OF H3 (A/HONG KONG/1/1968)
分子名称:Heavy chain of FluA-20 Fab, Light chain of FluA-20 Fab, Hemagglutinin, ...
著者Wilson, I.A., Lang, S.
登録日2019-03-22
公開日2019-05-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of FluA-20 Fab in complex with the head domain of H1 (A/Solomon Islands/3/2006)
To Be Published
1GAR
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TOWARDS STRUCTURE-BASED DRUG DESIGN: CRYSTAL STRUCTURE OF A MULTISUBSTRATE ADDUCT COMPLEX OF GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE AT 1.96 ANGSTROMS RESOLUTION
分子名称:GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE, N-[4-[[3-(2,4-DIAMINO-1,6-DIHYDRO-6-OXO-4-PYRIMIDINYL)-PROPYL]-[2-((2-OXO-2-((4-PHOSPHORIBOXY)-BUTYL)-AMINO)-ETHYL)-THIO-ACETYL]-AMINO]BENZOYL]-1-GLUTAMIC ACID
著者Wilson, I.A., Klein, C., Chen, P., Arevalo, J.H.
登録日1994-12-08
公開日1995-07-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Towards structure-based drug design: crystal structure of a multisubstrate adduct complex of glycinamide ribonucleotide transformylase at 1.96 A resolution.
J.Mol.Biol., 249, 1995
1KQ3
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CRYSTAL STRUCTURE OF A GLYCEROL DEHYDROGENASE (TM0423) FROM THERMOTOGA MARITIMA AT 1.5 A RESOLUTION
分子名称:glycerol dehydrogenase, ZINC ION, CHLORIDE ION, ...
著者Wilson, I.A., Miller, M.D., Joint Center for Structural Genomics (JCSG)
登録日2002-01-03
公開日2002-02-27
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline
Proc.Natl.Acad.Sci.USA, 99, 2002
1KQ4
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CRYSTAL STRUCTURE OF A THY1-COMPLEMENTING PROTEIN (TM0449) FROM THERMOTOGA MARITIMA AT 2.25 A RESOLUTION
分子名称:HYPOTHETICAL PROTEIN TM0449, FLAVIN-ADENINE DINUCLEOTIDE
著者Wilson, I.A., Miller, M.D., Joint Center for Structural Genomics (JCSG)
登録日2002-01-03
公開日2002-02-27
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline
Proc.Natl.Acad.Sci.USA, 99, 2002
1ZIW
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HUMAN TOLL-LIKE RECEPTOR 3 EXTRACELLULAR DOMAIN STRUCTURE
分子名称:Toll-like receptor 3, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, N-ACETYL-D-GLUCOSAMINE, ...
著者Wilson, I.A., Choe, J.
登録日2005-04-27
公開日2005-06-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of human toll-like receptor 3 (TLR3) ectodomain.
Science, 309, 2005
5CEY
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CRYSTAL STRUCTURE OF FAB 9H+3L, A PUTATIVE PRECURSOR OF THE PGT121 FAMILY OF POTENT HIV-1 ANTIBODIES
分子名称:Antibody 9H+3L Fab light chain, Antibody 9H+3L Fab heavy chain, GLYCEROL, ...
著者Wilson, I.A., Garces, F.
登録日2015-07-07
公開日2015-12-23
最終更新日2016-01-06
実験手法X-RAY DIFFRACTION (2.387 Å)
主引用文献Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.
Immunity, 43, 2015
5CEZ
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CRYSTAL STRUCTURE OF THE BG505 SOSIP GP140 HIV-1 ENV TRIMER IN COMPLEX WITH AN EARLY PUTATIVE PRECURSOR OF THE PGT121 FAMILY AT 3.0 ANGSTROM
分子名称:Envelope glycoprotein gp160, 3H+109L Fab Light Chain, 3H+109L Fab Heavy Chain, ...
著者Wilson, I.A., Garces, F.
登録日2015-07-08
公開日2015-12-23
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (3.031 Å)
主引用文献Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.
Immunity, 43, 2015
5T08
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CRYSTAL STRUCTURE OF H6 HEMAGGLUTININ G225D MUTANT FROM TAIWAN (2013) H6N1 INFLUENZA VIRUS
分子名称:Hemagglutinin, Hemagglutinin HA2 chain, N-ACETYL-D-GLUCOSAMINE
著者Wilson, I.A., Tzarum, N., Zhu, X.
登録日2016-08-15
公開日2017-06-14
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.1895 Å)
主引用文献A single mutation in Taiwanese H6N1 influenza hemagglutinin switches binding to human-type receptors.
EMBO Mol Med, 9, 2017
5T0B
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CRYSTAL STRUCTURE OF H6 HEMAGGLUTININ G225D MUTANT FROM TAIWAN (2013) H6N1 INFLUENZA VIRUS IN COMPLEX WITH 6'-SLN
分子名称:Hemagglutinin, Hemagglutinin HA2 chain, N-ACETYL-D-GLUCOSAMINE, ...
著者Wilson, I.A., Tzarum, N., Zhu, X.
登録日2016-08-15
公開日2017-06-14
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献A single mutation in Taiwanese H6N1 influenza hemagglutinin switches binding to human-type receptors.
EMBO Mol Med, 9, 2017
5T0D
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CRYSTAL STRUCTURE OF H6 HEMAGGLUTININ G225D MUTANT FROM TAIWAN (2013) H6N1 INFLUENZA VIRUS IN COMPLEX WITH 3'-SLN
分子名称:Hemagglutinin, Hemagglutinin HA2 chain, N-ACETYL-D-GLUCOSAMINE, ...
著者Wilson, I.A., Tzarum, N., Zhu, X.
登録日2016-08-15
公開日2017-06-14
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.864 Å)
主引用文献A single mutation in Taiwanese H6N1 influenza hemagglutinin switches binding to human-type receptors.
EMBO Mol Med, 9, 2017
5T0E
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CRYSTAL STRUCTURE OF H6 HEMAGGLUTININ G225D MUTANT FROM TAIWAN (2013) H6N1 INFLUENZA VIRUS IN COMPLEX WITH LSTA
分子名称:Hemagglutinin, Hemagglutinin HA2 chain, N-ACETYL-D-GLUCOSAMINE, ...
著者Wilson, I.A., Tzarum, N., Zhu, X.
登録日2016-08-15
公開日2017-06-14
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.089 Å)
主引用文献A single mutation in Taiwanese H6N1 influenza hemagglutinin switches binding to human-type receptors.
EMBO Mol Med, 9, 2017
5TG8
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CRYSTAL STRUCTURE OF H15 HEMAGGLUTININ FROM A/SHEARWATER/WA/2576/1979 H15N9 INFLUENZA VIRUS
分子名称:Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, N-ACETYL-D-GLUCOSAMINE
著者Wilson, I.A., Tzarum, N.
登録日2016-09-27
公開日2017-04-12
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Unique Structural Features of Influenza Virus H15 Hemagglutinin.
J. Virol., 91, 2017
5TG9
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CRYSTAL STRUCTURE OF H15 HEMAGGLUTININ FROM A/SHEARWATER/WA/2576/1979 H15N9 INFLUENZA VIRUS IN COMPLEX WITH 3'-SLN
分子名称:Hemagglutinin, Hemagglutinin HA2 chain, N-ACETYL-D-GLUCOSAMINE, ...
著者Wilson, I.A., Tzarum, N.
登録日2016-09-27
公開日2017-04-12
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (2.749 Å)
主引用文献Unique Structural Features of Influenza Virus H15 Hemagglutinin.
J. Virol., 91, 2017
5W5S
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CRYSTAL STRUCTURE OF THE A/PUERTO RICO/8/1934 (H1N1) INFLUENZA VIRUS HEMAGGLUTININ IN COMPLEX WITH CYCLIC PEPTIDE CP141019 (P5)
分子名称:Hemagglutinin, ACE-PH8-ORN-LEU-GLU-TYR-ZCL-GLU-TRP-LEU-SER-BAL, N-ACETYL-D-GLUCOSAMINE, ...
著者Wilson, I.A., Kadam, R.U.
登録日2017-06-15
公開日2017-10-04
最終更新日2017-12-06
実験手法X-RAY DIFFRACTION (2.284 Å)
主引用文献Potent peptidic fusion inhibitors of influenza virus.
Science, 358, 2017
5W5U
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CRYSTAL STRUCTURE OF THE A/PUERTO RICO/8/1934 (H1N1) INFLUENZA VIRUS HEMAGGLUTININ IN COMPLEX WITH CYCLIC PEPTIDE CP141037 (P4)
分子名称:Hemagglutinin, ACE-PH8-ORN-MLE-GLU-TYR-PHE-GLU-TRP-LEU-SER-BAL, N-ACETYL-D-GLUCOSAMINE, ...
著者Wilson, I.A., Kadam, R.U.
登録日2017-06-15
公開日2017-10-04
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.461 Å)
主引用文献Potent peptidic fusion inhibitors of influenza virus.
Science, 358, 2017
5W6I
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CRYSTAL STRUCTURE OF THE A/PUERTO RICO/8/1934 (H1N1) INFLUENZA VIRUS HEMAGGLUTININ IN COMPLEX WITH CYCLIC PEPTIDE CP141046 (P3)
分子名称:Hemagglutinin, ACE-PH8-ORN-LEU-GLU-TYR-PHE-GLU-TRP-LEU-SER-BAL, N-ACETYL-D-GLUCOSAMINE
著者Wilson, I.A., Kadam, R.U.
登録日2017-06-16
公開日2017-10-04
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (3.104 Å)
主引用文献Potent peptidic fusion inhibitors of influenza virus.
Science, 358, 2017
5W6R
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CRYSTAL STRUCTURE OF THE A/PUERTO RICO/8/1934 (H1N1) INFLUENZA VIRUS HEMAGGLUTININ IN COMPLEX WITH CYCLIC PEPTIDE CP141099 (P6)
分子名称:Hemagglutinin, ACE-PH8-ORN-LEU-GLU-TYR-PHE-GLU-TRP-LEU-SER-9WV, N-ACETYL-D-GLUCOSAMINE
著者Wilson, I.A., Kadam, R.U.
登録日2017-06-16
公開日2017-10-04
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.731 Å)
主引用文献Potent peptidic fusion inhibitors of influenza virus.
Science, 358, 2017
5W6T
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CRYSTAL STRUCTURE OF THE A/PUERTO RICO/8/1934 (H1N1) INFLUENZA VIRUS HEMAGGLUTININ IN COMPLEX WITH CYCLIC PEPTIDE CP151070 (P7)
分子名称:Hemagglutinin, ACE-PH8-ORN-MLE-GLU-TYR-ZCL-GLU-TRP-LEU-SER-9WV, N-ACETYL-D-GLUCOSAMINE, ...
著者Wilson, I.A., Kadam, R.U.
登録日2017-06-16
公開日2017-10-04
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Potent peptidic fusion inhibitors of influenza virus.
Science, 358, 2017
5W6U
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CRYSTAL STRUCTURE OF THE A/PUERTO RICO/8/1934 (H1N1) INFLUENZA VIRUS HEMAGGLUTININ IN COMPLEX WITH CYCLIC PEPTIDE CP121068 (P2)
分子名称:Hemagglutinin, ACE-ARG-ORN-LEU-GLU-TYR-PHE-GLU-TRP-LEU-SER-BAL, N-ACETYL-D-GLUCOSAMINE
著者Wilson, I.A., Kadam, R.U.
登録日2017-06-16
公開日2017-10-04
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.878 Å)
主引用文献Potent peptidic fusion inhibitors of influenza virus.
Science, 358, 2017
6CEX
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CRYSTAL STRUCTURE OF THE A/HONG KONG/1/1968 (H3N2) INFLUENZA VIRUS HEMAGGLUTININ IN COMPLEX WITH SMALL MOLECULE N-CYCLOHEXYLTAURINE
分子名称:Hemagglutinin, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, N-ACETYL-D-GLUCOSAMINE, ...
著者wilson, I.A., Kadam, R.U.
登録日2018-02-12
公開日2018-04-04
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献A small-molecule fragment that emulates binding of receptor and broadly neutralizing antibodies to influenza A hemagglutinin.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6CF5
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CRYSTAL STRUCTURE OF THE A/VIET NAM/1203/2004(H5N1) INFLUENZA VIRUS HEMAGGLUTININ IN COMPLEX WITH SMALL MOLECULE N-CYCLOHEXYLTAURINE
分子名称:Hemagglutinin, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, N-ACETYL-D-GLUCOSAMINE, ...
著者Wilson, I.A., Kadam, R.U.
登録日2018-02-13
公開日2018-04-04
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献A small-molecule fragment that emulates binding of receptor and broadly neutralizing antibodies to influenza A hemagglutinin.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6MU3
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ANTI-HIV-1 FAB 2G12 + MAN7 RE-REFINEMENT
分子名称:Fab 2G12, light chain, heavy chain, ...
著者Wilson, I.A., Calarese, D.A., Stanfield, R.L.
登録日2018-10-22
公開日2018-10-31
実験手法X-RAY DIFFRACTION (2.327 Å)
主引用文献Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12.
Proc. Natl. Acad. Sci. U.S.A., 102, 2005
6MUB
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ANTI-HIV-1 FAB 2G12 + MAN5 RE-REFINEMENT
分子名称:Fab 2G12, light chain, heavy chain, ...
著者Wilson, I.A., Calarese, D.A., Stanfield, R.L.
登録日2018-10-22
公開日2018-10-31
実験手法X-RAY DIFFRACTION (2.503 Å)
主引用文献Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12.
Proc. Natl. Acad. Sci. U.S.A., 102, 2005
6OBZ
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CRYSTAL STRUCTURE OF FLUA-20 FAB
分子名称:Heavy chain of FluA-20 Fab, Light chain of FluA-20 Fab, Immunoglobulin light chain
著者Wilson, I.A., Lang, S.
登録日2019-03-21
公開日2019-05-15
最終更新日2019-06-12
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献A Site of Vulnerability on the Influenza Virus Hemagglutinin Head Domain Trimer Interface.
Cell, 177, 2019