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4LK3
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CRYSTAL STRUCTURE OF HUMAN UDP-XYLOSE SYNTHASE R236A SUBSTITUTION
Descriptor:UDP-glucuronic acid decarboxylase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, URIDINE-5'-DIPHOSPHATE, ...
Authors:Walsh Jr., R.M., Polizzi, S.J., Wood, Z.A.
Deposit date:2013-07-05
Release date:2013-08-07
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Man o' war mutation in UDP-alpha-D-xylose synthase favors the abortive catalytic cycle and uncovers a latent potential for hexamer formation.
Biochemistry, 54, 2015
4M55
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CRYSTAL STRUCTURE OF HUMAN UDP-XYLOSE SYNTHASE R236H SUBSTITUTION
Descriptor:UDP-glucuronic acid decarboxylase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PYROPHOSPHATE 2-, ...
Authors:Walsh Jr., R.M., Polizzi, S.J., Wood, Z.A.
Deposit date:2013-08-08
Release date:2013-08-28
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Man o' war mutation in UDP-alpha-D-xylose synthase favors the abortive catalytic cycle and uncovers a latent potential for hexamer formation.
Biochemistry, 54, 2015
4S3M
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EVIDENCE OF KINETIC COOPERATIVITY IN DIMERIC KETOPANTOATE REDUCTASE FROM STAPHYLOCOCCUS AUREUS
Descriptor:2-dehydropantoate 2-reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Sanchez, J.E., Walsh Jr., R.M., Wood, Z.A.
Deposit date:2015-02-19
Release date:2015-03-11
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Evidence of Kinetic Cooperativity in Dimeric Ketopantoate Reductase from Staphylococcus aureus.
Biochemistry, 54, 2015
4YCA
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EVIDENCE OF KINETIC COOPERATIVITY IN DIMERIC KETOPANTOATE REDUCTASE FROM STAPHYLOCOCCUS AUREUS
Descriptor:2-dehydropantoate 2-reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Sanchez, J.E., Gross, P.G., Goetze, R., Walsh Jr., R.M., Peeples, W.B., Wood, Z.A.
Deposit date:2015-02-19
Release date:2015-03-11
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Evidence of Kinetic Cooperativity in Dimeric Ketopantoate Reductase from Staphylococcus aureus.
Biochemistry, 54, 2015
6XR8
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DISTINCT CONFORMATIONAL STATES OF SARS-COV-2 SPIKE PROTEIN
Descriptor:Spike glycoprotein, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Zhang, J., Cai, Y.F., Xiao, T.S., Peng, H.Q., Sterling, S.M., Walsh Jr, R.M., Rawson, S., Volloch, S.R., Chen, B.
Deposit date:2020-07-11
Release date:2020-07-22
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Distinct conformational states of SARS-CoV-2 spike protein
Science, 2020
6XRA
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DISTINCT CONFORMATIONAL STATES OF SARS-COV-2 SPIKE PROTEIN
Descriptor:Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Zhang, J., Cai, Y.F., Xiao, T.S., Peng, H.Q., Sterling, S.M., Walsh Jr, R.M., Rawson, S., Rits-Volloch, S., Chen, B.
Deposit date:2020-07-11
Release date:2020-07-22
Last modified:2020-08-05
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Distinct conformational states of SARS-CoV-2 spike protein.
Science, 2020
6CNJ
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STRUCTURE OF THE 2ALPHA3BETA STIOCHIOMETRY OF THE HUMAN ALPHA4BETA2 NICOTINIC RECEPTOR
Descriptor:Neuronal acetylcholine receptor subunit alpha-4, Neuronal acetylcholine receptor subunit beta-2, IgG1 Kappa Light Chain, ...
Authors:Walsh Jr, R.M., Roh, S.H., Gharpure, A., Morales-Perez, C.L., Teng, J., Hibbs, R.E.
Deposit date:2018-03-08
Release date:2018-05-02
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural principles of distinct assemblies of the human alpha 4 beta 2 nicotinic receptor.
Nature, 557, 2018
6CNK
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STRUCTURE OF THE 3ALPHA2BETA STIOCHIOMETRY OF THE HUMAN ALPHA4BETA2 NICOTINIC RECEPTOR
Descriptor:Neuronal acetylcholine receptor subunit alpha-4, Neuronal acetylcholine receptor subunit beta-2, IgG1 Kappa Light Chain, ...
Authors:Walsh Jr, R.M., Roh, S.H., Gharpure, A., Morales-Perez, C.L., Hibbs, R.E.
Deposit date:2018-03-08
Release date:2018-05-02
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural principles of distinct assemblies of the human alpha 4 beta 2 nicotinic receptor.
Nature, 557, 2018
6D6T
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HUMAN GABA-A RECEPTOR ALPHA1-BETA2-GAMMA2 SUBTYPE IN COMPLEX WITH GABA AND FLUMAZENIL, CONFORMATION B
Descriptor:Gamma-aminobutyric acid receptor subunit beta-2,Gamma-aminobutyric acid receptor subunit beta-2, Gamma-aminobutyric acid receptor subunit alpha-1,Gamma-aminobutyric acid receptor subunit alpha-1, Human GABA-A receptor subunit gamma-2, ...
Authors:Zhu, S., Noviello, C.M., Teng, J., Walsh Jr, R.M., Kim, J.J., Hibbs, R.E.
Deposit date:2018-04-22
Release date:2018-06-27
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of a human synaptic GABAAreceptor.
Nature, 559, 2018
6D6U
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HUMAN GABA-A RECEPTOR ALPHA1-BETA2-GAMMA2 SUBTYPE IN COMPLEX WITH GABA AND FLUMAZENIL, CONFORMATION A
Descriptor:Gamma-aminobutyric acid receptor subunit beta-2,Gamma-aminobutyric acid receptor subunit beta-2, Gamma-aminobutyric acid receptor subunit alpha-1,Gamma-aminobutyric acid receptor subunit alpha-1, Gamma-aminobutyric acid receptor subunit gamma-2,Gamma-aminobutyric acid receptor subunit gamma-2, ...
Authors:Zhu, S., Noviello, C.M., Teng, J., Walsh Jr, R.M., Kim, J.J., Hibbs, R.E.
Deposit date:2018-04-22
Release date:2018-06-27
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of a human synaptic GABAAreceptor.
Nature, 559, 2018
6PV7
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HUMAN ALPHA3BETA4 NICOTINIC ACETYLCHOLINE RECEPTOR IN COMPLEX WITH NICOTINE
Descriptor:Fusion protein of Neuronal acetylcholine receptor subunit alpha-3 and Soluble cytochrome b562, Fusion protein of Neuronal acetylcholine receptor subunit beta-4 and Soluble cytochrome b562, IgG2b Fab heavy chain, ...
Authors:Gharpure, A., Teng, J., Zhuang, Y., Noviello, C.M., Walsh, R.M., Cabuco, R., Howard, R.J., Zaveri, N.T., Lindahl, E., Hibbs, R.E.
Deposit date:2019-07-19
Release date:2019-09-11
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:Agonist Selectivity and Ion Permeation in the alpha 3 beta 4 Ganglionic Nicotinic Receptor.
Neuron, 104, 2019
6PV8
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HUMAN ALPHA3BETA4 NICOTINIC ACETYLCHOLINE RECEPTOR IN COMPLEX WITH AT-1001
Descriptor:Fusion protein of Neuronal acetylcholine receptor subunit alpha-3 and Soluble cytochrome b562, Fusion protein of Neuronal acetylcholine receptor subunit beta-4 and Soluble cytochrome b562, IgG2b Fab heavy chain, ...
Authors:Gharpure, A., Teng, J., Zhuang, Y., Noviello, C.M., Walsh, R.M., Cabuco, R., Howard, R.J., Zaveri, N.T., Lindahl, E., Hibbs, R.E.
Deposit date:2019-07-19
Release date:2019-09-11
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.87 Å)
Cite:Agonist Selectivity and Ion Permeation in the alpha 3 beta 4 Ganglionic Nicotinic Receptor.
Neuron, 104, 2019
4GLL
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CRYSTAL STRUCTURE OF HUMAN UDP-XYLOSE SYNTHASE.
Descriptor:UDP-glucuronic acid decarboxylase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, GUANIDINE, ...
Authors:Wood, Z.A., Polizzi, S.J.
Deposit date:2012-08-14
Release date:2012-09-05
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Human UDP-alpha-d-xylose Synthase and Escherichia coli ArnA Conserve a Conformational Shunt That Controls Whether Xylose or 4-Keto-Xylose Is Produced.
Biochemistry, 51, 2012
4RJT
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CRYSTAL STRUCTURE OF UNLIGANDED, FULL LENGTH HUGDH AT PH 7.0
Descriptor:UDP-glucose 6-dehydrogenase, CHLORIDE ION
Authors:Sidlo, A.M., Wood, Z.A.
Deposit date:2014-10-09
Release date:2014-12-31
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Hysteresis in Human UDP-Glucose Dehydrogenase Is Due to a Restrained Hexameric Structure That Favors Feedback Inhibition.
Biochemistry, 53, 2014
167518
PDB entries from 2020-08-12