Author results

1DXP
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INHIBITION OF THE HEPATITIS C VIRUS NS3/4A PROTEASE. THE CRYSTAL STRUCTURES OF TWO PROTEASE-INHIBITOR COMPLEXES (APO STRUCTURE)
Descriptor:PROTEASE/HELICASE NS3 (P70), NONSTRUCTURAL PROTEIN NS4A (P4), ZINC ION, ...
Authors:Di Marco, S., Rizzi, M., Volpari, C., Walsh, M., Narjes, F., Colarusso, S., De Francesco, R., Matassa, V.G., Sollazzo, M.
Deposit date:2000-01-13
Release date:2001-01-12
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Inhibition of the Hepatitis C Virus Ns3/4A Protease the Crystal Structures of Two Protease-Inhibitor Complexes
J.Biol.Chem., 275, 2000
1DY8
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INHIBITION OF THE HEPATITIS C VIRUS NS3/4A PROTEASE. THE CRYSTAL STRUCTURES OF TWO PROTEASE-INHIBITOR COMPLEXES (INHIBITOR II)
Descriptor:PROTEASE/HELICASE NS3 (P70), NONSTRUCTURAL PROTEIN NS4A (P4), N-[(benzyloxy)carbonyl]-L-isoleucyl-N-[(1R)-1-(carboxycarbonyl)-3,3-difluoropropyl]-L-leucinamide
Authors:Di Marco, S., Rizzi, M., Volpari, C., Walsh, M., Narjes, F., Colarusso, S., De Francesco, R., Matassa, V.G., Sollazzo, M.
Deposit date:2000-01-31
Release date:2001-01-28
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Inhibition of the Hepatitis C Virus Ns3/4A Protease the Crystal Structures of Two Protease-Inhibitor Complexes
J.Biol.Chem., 275, 2000
1DY9
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INHIBITION OF THE HEPATITIS C VIRUS NS3/4A PROTEASE. THE CRYSTAL STRUCTURES OF TWO PROTEASE-INHIBITOR COMPLEXES (INHIBITOR I)
Descriptor:PROTEASE/HELICASE NS3 (P70), NONSTRUCTURAL PROTEIN NS4A (P4), N-(tert-butoxycarbonyl)-L-alpha-glutamyl-N-[(1R)-1-(carboxycarbonyl)-3,3-difluoropropyl]-L-leucinamide, ...
Authors:Di Marco, S., Rizzi, M., Volpari, C., Walsh, M., Narjes, F., Colarusso, S., De Francesco, R., Matassa, V.G., Sollazzo, M.
Deposit date:2000-01-31
Release date:2001-01-28
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Inhibition of the Hepatitis C Virus Ns3/4A Protease the Crystal Structures of Two Protease-Inhibitor Complexes
J.Biol.Chem., 275, 2000
3BJH
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SOFT-SAD CRYSTAL STRUCTURE OF A PHEROMONE BINDING PROTEIN FROM THE HONEYBEE APIS MELLIFERA L.
Descriptor:Pheromone-binding protein ASP1, N-BUTYL-BENZENESULFONAMIDE, GLYCEROL
Authors:Lartigue, A., Gruez, A., Briand, L., Blon, F., Bezirard, V., Walsh, M., Pernollet, J.C., Tegoni, M., Cambillau, C.
Deposit date:2007-12-04
Release date:2007-12-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Sulfur single-wavelength anomalous diffraction crystal structure of a pheromone-binding protein from the honeybee Apis mellifera L.
J.Biol.Chem., 279, 2004
3SRK
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A NEW CLASS OF SUICIDE INHIBITOR BLOCKS NUCLEOTIDE BINDING TO PYRUVATE KINASE
Descriptor:Pyruvate kinase, 1,2-BENZISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDE, POTASSIUM ION, ...
Authors:Morgan, H.P., Walsh, M., Blackburn, E.A., Wear, M.A., Boxer, M., Shen, M., McNae, I.W., Michels, P.A.M., Auld, D.S., Fothergill-Gilmore, L.A., Walkinshaw, M.D.
Deposit date:2011-07-07
Release date:2012-07-18
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:A new class of suicide inhibitor blocks nucleotide binding to pyruvate kinase
To be Published
1SFK
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CORE (C) PROTEIN FROM WEST NILE VIRUS, SUBTYPE KUNJIN
Descriptor:Core protein, CALCIUM ION, CHLORIDE ION, ...
Authors:Dokland, T., Walsh, M., Mackenzie, J.M., Khromykh, A.A., Ee, K.-H., Wang, S.
Deposit date:2004-02-19
Release date:2004-08-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:West nile virus core protein; tetramer structure and ribbon formation
Structure, 12, 2004
1UW7
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NSP9 PROTEIN FROM SARS-CORONAVIRUS.
Descriptor:NSP9
Authors:Sutton, G., Fry, E., Carter, L., Sainsbury, S., Walter, T., Nettleship, J., Berrow, N., Owens, R., Gilbert, R., Davidson, A., Siddell, S., Poon, L.L.M., Diprose, J., Alderton, D., Walsh, M., Grimes, J.M., Stuart, D.I.
Deposit date:2004-01-30
Release date:2004-02-20
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Nsp9 Replicase Protein of Sars-Coronavirus, Structure and Functional Insights
Structure, 12, 2004
4YW4
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STREPTOCOCCUS PNEUMONIAE SIALIDASE NANC
Descriptor:Neuraminidase C, PHOSPHATE ION, GLYCEROL
Authors:Owen, C.D., Lukacik, P., Potter, J.A., Walsh, M., Taylor, G.L.
Deposit date:2015-03-20
Release date:2016-04-13
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a novel sialidase
To be published
4B7F
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STRUCTURE OF A LIGANDED BACTERIAL CATALASE
Descriptor:Catalase, CHLORIDE ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Gumiero, A., Walsh, M.
Deposit date:2012-08-20
Release date:2013-08-28
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:A Structural and Dynamic Investigation of the Inhibition of Catalase by Nitric Oxide.
Org.Biomol.Chem., 11, 2013
4B7G
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STRUCTURE OF A BACTERIAL CATALASE
Descriptor:CATALASE, CHLORIDE ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Gumiero, A., Walsh, M.
Deposit date:2012-08-20
Release date:2013-08-28
Last modified:2014-04-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Structural and Dynamic Investigation of the Inhibition of Catalase by Nitric Oxide.
Org.Biomol.Chem., 11, 2013
4B7H
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STRUCTURE OF A HIGHDOSE LIGANDED BACTERIAL CATALASE
Descriptor:CATALASE, PROTOPORPHYRIN IX CONTAINING FE, NITRIC OXIDE, ...
Authors:Gumiero, A., Walsh, M.
Deposit date:2012-08-20
Release date:2013-08-28
Last modified:2014-04-23
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:A Structural and Dynamic Investigation of the Inhibition of Catalase by Nitric Oxide.
Org.Biomol.Chem., 11, 2013
1AKQ
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D95A OXIDIZED FLAVODOXIN MUTANT FROM D. VULGARIS
Descriptor:FLAVODOXIN, FLAVIN MONONUCLEOTIDE
Authors:Mccarthy, A., Walsh, M., Higgins, T.
Deposit date:1997-03-27
Release date:1998-12-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystallographic investigation of the role of aspartate 95 in the modulation of the redox potentials of Desulfovibrio vulgaris flavodoxin.
Biochemistry, 41, 2002
1AKR
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G61A OXIDIZED FLAVODOXIN MUTANT
Descriptor:FLAVODOXIN, FLAVIN MONONUCLEOTIDE
Authors:Mccarthy, A., Walsh, M., Higgins, T.
Deposit date:1997-05-27
Release date:1998-05-27
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Modulation of the redox potentials of FMN in Desulfovibrio vulgaris flavodoxin: thermodynamic properties and crystal structures of glycine-61 mutants.
Biochemistry, 37, 1998
1AKT
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G61N OXIDIZED FLAVODOXIN MUTANT
Descriptor:FLAVODOXIN, FLAVIN MONONUCLEOTIDE
Authors:Mccarthy, A., Walsh, M., Higgins, T.
Deposit date:1997-05-27
Release date:1998-05-27
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Modulation of the redox potentials of FMN in Desulfovibrio vulgaris flavodoxin: thermodynamic properties and crystal structures of glycine-61 mutants.
Biochemistry, 37, 1998
1AKU
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D95A HYDROQUINONE FLAVODOXIN MUTANT FROM D. VULGARIS
Descriptor:FLAVODOXIN, SULFATE ION, FLAVIN MONONUCLEOTIDE
Authors:Mccarthy, A., Walsh, M., Higgins, T.
Deposit date:1997-05-27
Release date:1998-12-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystallographic investigation of the role of aspartate 95 in the modulation of the redox potentials of Desulfovibrio vulgaris flavodoxin.
Biochemistry, 41, 2002
1AKV
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D95A SEMIQUINONE FLAVODOXIN MUTANT FROM D. VULGARIS
Descriptor:FLAVODOXIN, SULFATE ION, FLAVIN MONONUCLEOTIDE
Authors:Mccarthy, A., Walsh, M., Higgins, T.
Deposit date:1997-05-27
Release date:1998-12-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallographic investigation of the role of aspartate 95 in the modulation of the redox potentials of Desulfovibrio vulgaris flavodoxin.
Biochemistry, 41, 2002
1AKW
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G61L OXIDIZED FLAVODOXIN MUTANT
Descriptor:FLAVODOXIN, FLAVIN MONONUCLEOTIDE
Authors:Mccarthy, A., Walsh, M., Higgins, T.
Deposit date:1997-05-27
Release date:1998-05-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Modulation of the redox potentials of FMN in Desulfovibrio vulgaris flavodoxin: thermodynamic properties and crystal structures of glycine-61 mutants.
Biochemistry, 37, 1998
1C7E
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D95E HYDROQUINONE FLAVODOXIN MUTANT FROM D. VULGARIS
Descriptor:FLAVODOXIN, FLAVIN MONONUCLEOTIDE
Authors:McCarthy, A., Walsh, M., Higgins, T., D'Arcy, D.
Deposit date:2000-02-16
Release date:2000-08-23
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystallographic Investigation of the Role of Aspartate 95 in the Modulation of the Redox Potentials Of Desulfovibrio Vulgaris Flavodoxin
Biochemistry, 41, 2002
1C7F
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D95E OXIDIZED FLAVODOXIN MUTANT FROM D. VULGARIS
Descriptor:FLAVODOXIN, FLAVIN MONONUCLEOTIDE
Authors:McCarthy, A., Walsh, M., Higgins, T., D'Arcy, D.
Deposit date:2000-02-11
Release date:2000-08-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallographic Investigation of the Role of Aspartate 95 in the Modulation of the Redox Potentials Of Desulfovibrio Vulgaris Flavodoxin
Biochemistry, 41, 2002
5FR7
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ERWINIA AMYLOVORA AMYR AMYLOVORAN REPRESSOR, A MEMBER OF THE YBJN PROTEIN FAMILY
Descriptor:AMYR
Authors:Bartho, J.D., Bellini, D., Wuerges, J., Demitri, N., Walsh, M., Benini, S.
Deposit date:2015-12-16
Release date:2017-01-18
Last modified:2017-05-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The crystal structure of Erwinia amylovora AmyR, a member of the YbjN protein family, shows similarity to type III secretion chaperones but suggests different cellular functions.
PLoS ONE, 12, 2017
5FRK
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SEMET CRYSTAL STRUCTURE OF ERWINIA AMYLOVORA AMYR AMYLOVORAN REPRESSOR, A MEMBER OF THE YBJN PROTEIN FAMILY
Descriptor:AMYR
Authors:Bartho, J.D., Bellini, D., Wuerges, J., Demitri, N., Walsh, M., Benini, S.
Deposit date:2015-12-18
Release date:2017-02-15
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:The crystal structure of Erwinia amylovora AmyR, a member of the YbjN protein family, shows similarity to type III secretion chaperones but suggests different cellular functions.
PLoS ONE, 12, 2017
2I9F
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STRUCTURE OF THE EQUINE ARTERIVIRUS NUCLEOCAPSID PROTEIN
Descriptor:Nucleocapsid, GLYCEROL, CHLORIDE ION, ...
Authors:Deshpande, A., Wang, S., Walsh, M., Dokland, T.
Deposit date:2006-09-05
Release date:2007-05-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the equine arteritis virus nucleocapsid protein reveals a dimer-dimer arrangement.
Acta Crystallogr.,Sect.D, 63, 2007
4YW1
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CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE NANC, COMPLEX WITH NEU5AC AND NEU5AC2EN FOLLOWING SOAKING WITH 3'SL
Descriptor:Neuraminidase C, O-SIALIC ACID, PHOSPHATE ION, ...
Authors:Owen, C.D., Lukacik, P., Potter, J.A., Walsh, M., Taylor, G.L.
Deposit date:2015-03-20
Release date:2015-09-23
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Streptococcus pneumoniae NanC: STRUCTURAL INSIGHTS INTO THE SPECIFICITY AND MECHANISM OF A SIALIDASE THAT PRODUCES A SIALIDASE INHIBITOR.
J.Biol.Chem., 290, 2015
4YW2
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CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE NANC, COMPLEX 6'SL
Descriptor:Sialidase B, PHOSPHATE ION, GLYCEROL, ...
Authors:Owen, C.D., Lukacik, P., Potter, J.A., Walsh, M., Taylor, G.L.
Deposit date:2015-03-20
Release date:2015-09-23
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Streptococcus pneumoniae NanC: STRUCTURAL INSIGHTS INTO THE SPECIFICITY AND MECHANISM OF A SIALIDASE THAT PRODUCES A SIALIDASE INHIBITOR.
J.Biol.Chem., 290, 2015
4YW3
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CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE NANC, COMPLEX WITH NEU5AC AND NEU5AC2EN FOLLOWING SOAKING WITH NEU5AC2EN
Descriptor:Neuraminidase C, PHOSPHATE ION, O-SIALIC ACID, ...
Authors:Owen, C.D., Lukacik, P., Potter, J.A., Walsh, M., Taylor, G.L.
Deposit date:2015-03-20
Release date:2015-09-23
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Streptococcus pneumoniae NanC: STRUCTURAL INSIGHTS INTO THE SPECIFICITY AND MECHANISM OF A SIALIDASE THAT PRODUCES A SIALIDASE INHIBITOR.
J.Biol.Chem., 290, 2015
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