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7KKJ
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STRUCTURE OF ANTI-SARS-COV-2 SPIKE NANOBODY MNB6
Descriptor:Synthetic nanobody mNb6, SULFATE ION, CHLORIDE ION
Authors:Schoof, M.S., Faust, B.F., Saunders, R.A., Sangwan, S., Rezelj, V., Hoppe, N., Boone, M., Billesboelle, C.B., Puchades, C., Azumaya, C.M., Kratochvil, H.T., Zimanyi, M., Desphande, I., Liang, J., Dickinson, S., Nguyen, H.C., Chio, C.M., Merz, G.E., Thompson, M.C., Diwanji, D., Schaefer, K., Anand, A.A., Dobzinski, N., Zha, B.S., Simoneau, C.R., Leon, K., White, K.M., Chio, U.S., Gupta, M., Jin, M., Li, F., Liu, Y., Zhang, K., Bulkley, D., Sun, M., Smith, A.M., Rizo, A.N., Moss, F., Brilot, A.F., Pourmal, S., Trenker, R., Pospiech, T., Gupta, S., Barsi-Rhyne, B., Belyy, V., Barile-Hill, A.W., Nock, S., Liu, Y., Krogan, N.J., Ralston, C.Y., Swaney, D.L., Garcia-Sastre, A., Ott, M., Vignuzzi, M., Walter, P., Manglik, A., QCRG Structural Biology Consortium
Deposit date:2020-10-27
Release date:2020-11-25
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Science, 2020
7KKK
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SARS-COV-2 SPIKE IN COMPLEX WITH NEUTRALIZING NANOBODY NB6
Descriptor:SARS-CoV-2 spike glycoprotein, Synthetic nanobody Nb6, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Schoof, M.S., Faust, B.F., Saunders, R.A., Sangwan, S., Rezelj, V., Hoppe, N., Boone, M., Billesboelle, C.B., Puchades, C., Azumaya, C.M., Kratochvil, H.T., Zimanyi, M., Desphande, I., Liang, J., Dickinson, S., Nguyen, H.C., Chio, C.M., Merz, G.E., Thompson, M.C., Diwanji, D., Schaefer, K., Anand, A.A., Dobzinski, N., Zha, B.S., Simoneau, C.R., Leon, K., White, K.M., Chio, U.S., Gupta, M., Jin, M., Li, F., Liu, Y., Zhang, K., Bulkley, D., Sun, M., Smith, A.M., Rizo, A.N., Moss, F., Brilot, A.F., Pourmal, S., Trenker, R., Pospiech, T., Gupta, S., Barsi-Rhyne, B., Belyy, V., Barile-Hill, A.W., Nock, S., Liu, Y., Krogan, N.J., Ralston, C.Y., Swaney, D.L., Garcia-Sastre, A., Ott, M., Vignuzzi, M., Walter, P., Manglik, A., QCRG Structural Biology Consortium
Deposit date:2020-10-27
Release date:2020-11-11
Last modified:2020-11-25
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Science, 2020
7KKL
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SARS-COV-2 SPIKE IN COMPLEX WITH NEUTRALIZING NANOBODY MNB6
Descriptor:SARS-CoV-2 spike glycoprotein, Synthetic nanobody mNb6, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Schoof, M.S., Faust, B.F., Saunders, R.A., Sangwan, S., Rezelj, V., Hoppe, N., Boone, M., Billesboelle, C.B., Puchades, C., Azumaya, C.M., Kratochvil, H.T., Zimanyi, M., Desphande, I., Liang, J., Dickinson, S., Nguyen, H.C., Chio, C.M., Merz, G.E., Thompson, M.C., Diwanji, D., Schaefer, K., Anand, A.A., Dobzinski, N., Zha, B.S., Simoneau, C.R., Leon, K., White, K.M., Chio, U.S., Gupta, M., Jin, M., Li, F., Liu, Y., Zhang, K., Bulkley, D., Sun, M., Smith, A.M., Rizo, A.N., Moss, F., Brilot, A.F., Pourmal, S., Trenker, R., Pospiech, T., Gupta, S., Barsi-Rhyne, B., Belyy, V., Barile-Hill, A.W., Nock, S., Liu, Y., Krogan, N.J., Ralston, C.Y., Swaney, D.L., Garcia-Sastre, A., Ott, M., Vignuzzi, M., Walter, P., Manglik, A., QCRG Structural Biology Consortium
Deposit date:2020-10-27
Release date:2020-11-11
Last modified:2020-11-25
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Science, 2020
7KDT
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HUMAN TOM70 IN COMPLEX WITH SARS COV2 ORF9B
Descriptor:Mitochondrial import receptor subunit TOM70, ORF9b protein
Authors:QCRG Structural Biology Consortium
Deposit date:2020-10-09
Release date:2020-10-21
Last modified:2020-11-04
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.
Science, 2020
4WFX
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COXSACKIEVIRUS B3 POLYMERASE - F232L MUTANT - NACL CRYSTAL FORM
Descriptor:RNA-directed RNA polymerase, SODIUM ION
Authors:Peersen, O.B., McDonald, S.M.
Deposit date:2014-09-17
Release date:2014-10-22
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (1.808 Å)
Cite:Structure-Function Relationships Underlying the Replication Fidelity of Viral RNA-Dependent RNA Polymerases.
J.Virol., 89, 2015
4WFY
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COXSACKIEVIRUS B3 POLYMERASE - F232L MUTANT - AMSO4 CRYSTAL FORM
Descriptor:RNA-directed RNA polymerase, GLYCEROL, SULFATE ION
Authors:Peersen, O.B., McDonald, S.M.
Deposit date:2014-09-17
Release date:2014-10-22
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structure-Function Relationships Underlying the Replication Fidelity of Viral RNA-Dependent RNA Polymerases.
J.Virol., 89, 2015
4WFZ
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COXSACKIEVIRUS B3 3DPOL RNA DEPENDENT RNA POLYMERASE - NACL CRYSTAL FORM
Descriptor:RNA-directed RNA polymerase, SODIUM ION
Authors:Peersen, O.B., McDonald, S.M.
Deposit date:2014-09-17
Release date:2014-10-22
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (1.803 Å)
Cite:Structure-Function Relationships Underlying the Replication Fidelity of Viral RNA-Dependent RNA Polymerases.
J.Virol., 89, 2015
4ZP6
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COXSACKIEVIRUS B3 POLYMERASE - F364A MUTANT
Descriptor:Genome polyprotein, SULFATE ION
Authors:Peersen, O.B., McDonald, S.M.
Deposit date:2015-05-07
Release date:2016-05-11
Last modified:2016-07-13
Method:X-RAY DIFFRACTION (1.648 Å)
Cite:Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo.
J.Biol.Chem., 291, 2016
4ZP7
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COXSACKIEVIRUS B3 POLYMERASE - F364V MUTANT
Descriptor:Genome polyprotein
Authors:Peersen, O.B., McDonald, S.M.
Deposit date:2015-05-07
Release date:2016-05-11
Last modified:2016-07-13
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo.
J.Biol.Chem., 291, 2016
4ZP8
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COXSACKIEVIRUS B3 POLYMERASE - F364L MUTANT
Descriptor:RNA-dependent RNA polymerase
Authors:Peersen, O.B., McDonald, S.M.
Deposit date:2015-05-07
Release date:2016-05-11
Last modified:2016-07-13
Method:X-RAY DIFFRACTION (1.894 Å)
Cite:Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo.
J.Biol.Chem., 291, 2016
4ZP9
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COXSACKIEVIRUS B3 POLYMERASE - F364I MUTANT
Descriptor:RNA-dependent RNA polymerase
Authors:Peersen, O.B., McDonald, S.M.
Deposit date:2015-05-07
Release date:2016-05-11
Last modified:2016-07-13
Method:X-RAY DIFFRACTION (1.799 Å)
Cite:Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo.
J.Biol.Chem., 291, 2016
4ZPA
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COXSACKIEVIRUS B3 POLYMERASE - F364Y MUTANT
Descriptor:RNA-directed RNA polymerase, SULFATE ION
Authors:Peersen, O.B., McDonald, S.M.
Deposit date:2015-05-07
Release date:2016-05-11
Last modified:2016-07-13
Method:X-RAY DIFFRACTION (2.665 Å)
Cite:Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo.
J.Biol.Chem., 291, 2016
4ZPB
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COXSACKIEVIRUS B3 POLYMERASE - F364W MUTANT
Descriptor:RNA-directed RNA polymerase
Authors:Peersen, O.B., McDonald, S.M.
Deposit date:2015-05-07
Release date:2016-05-11
Last modified:2016-07-13
Method:X-RAY DIFFRACTION (1.797 Å)
Cite:Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo.
J.Biol.Chem., 291, 2016
4ZPC
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COXSACKIEVIRUS B3 POLYMERASE - A341G MUTANT
Descriptor:RNA-dependent RNA polymerase
Authors:Peersen, O.B., McDonald, S.M.
Deposit date:2015-05-07
Release date:2016-05-11
Last modified:2016-07-13
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo.
J.Biol.Chem., 291, 2016
4ZPD
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COXSACKIEVIRUS B3 POLYMERASE - A345V MUTANT
Descriptor:RNA-directed RNA polymerase
Authors:Peersen, O.B., McDonald, S.M.
Deposit date:2015-05-07
Release date:2016-05-11
Last modified:2016-07-13
Method:X-RAY DIFFRACTION (1.797 Å)
Cite:Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo.
J.Biol.Chem., 291, 2016
171588
PDB entries from 2020-11-25