Author results

2P4V
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CRYSTAL STRUCTURE OF THE TRANSCRIPT CLEAVAGE FACTOR, GREB AT 2.6A RESOLUTION
Descriptor:Transcription elongation factor greB
Authors:Vassylyeva, M.N., Svetlov, V., Dearborn, A.D., Klyuyev, S., Artsimovitch, I., Vassylyev, D.G.
Deposit date:2007-03-13
Release date:2008-01-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The carboxy-terminal coiled-coil of the RNA polymerase beta'-subunit is the main binding site for Gre factors.
Embo Rep., 8, 2007
2A6E
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CRYSTAL STRUCTURE OF THE T. THERMOPHILUS RNA POLYMERASE HOLOENZYME
Descriptor:DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
Authors:Artsimovitch, I., Vassylyeva, M.N., Svetlov, D., Svetlov, V., Perederina, A., Igarashi, N., Matsugaki, N., Wakatsuki, S., Tahirov, T.H., Vassylyev, D.G., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-07-02
Release date:2005-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins.
Cell(Cambridge,Mass.), 122, 2005
1SMY
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STRUCTURAL BASIS FOR TRANSCRIPTION REGULATION BY ALARMONE PPGPP
Descriptor:DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
Authors:Artsimovitch, I., Patlan, V., Sekine, S., Vassylyeva, M.N., Hosaka, T., Ochi, K., Yokoyama, S., Vassylyev, D.G., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-03-10
Release date:2004-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for transcription regulation by alarmone ppGpp
Cell(Cambridge,Mass.), 117, 2004
1TJL
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CRYSTAL STRUCTURE OF TRANSCRIPTION FACTOR DKSA FROM E. COLI
Descriptor:DnaK suppressor protein, ZINC ION
Authors:Perederina, A., Svetlov, V., Vassylyeva, M.N., Artsimovitch, I., Yokoyama, S., Vassylyev, D.G., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-06-06
Release date:2004-09-07
Last modified:2014-04-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Regulation through the secondary channel--structural framework for ppGpp-DksA synergism during transcription
Cell(Cambridge,Mass.), 118, 2004
1UC8
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CRYSTAL STRUCTURE OF A LYSINE BIOSYNTHESIS ENZYME, LYSX, FROM THERMUS THERMOPHILUS HB8
Descriptor:lysine biosynthesis enzyme
Authors:Sakai, H., Vassylyeva, M.N., Matsuura, T., Sekine, S., Nishiyama, M., Terada, T., Shirouzu, M., Kuramitsu, S., Vassylyev, D.G., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-04-09
Release date:2003-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of a Lysine Biosynthesis Enzyme, LysX, from Thermus thermophilus HB8
J.Mol.Biol., 332, 2003
1UC9
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CRYSTAL STRUCTURE OF A LYSINE BIOSYNTHESIS ENZYME, LYSX, FROM THERMUS THERMOPHILUS HB8
Descriptor:lysine biosynthesis enzyme, ADENOSINE-5'-DIPHOSPHATE
Authors:Sakai, H., Vassylyeva, M.N., Matsuura, T., Sekine, S., Nishiyama, M., Terada, T., Shirouzu, M., Kuramitsu, S., Vassylyev, D.G., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-04-09
Release date:2003-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Crystal Structure of a Lysine Biosynthesis Enzyme, LysX, from Thermus thermophilus HB8
J.Mol.Biol., 332, 2003
2A68
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CRYSTAL STRUCTURE OF THE T. THERMOPHILUS RNA POLYMERASE HOLOENZYME IN COMPLEX WITH ANTIBIOTIC RIFABUTIN
Descriptor:DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
Authors:Artsimovitch, I., Vassylyeva, M.N., Svetlov, D., Svetlov, V., Perederina, A., Igarashi, N., Matsugaki, N., Wakatsuki, S., Tahirov, T.H., Vassylyev, D.G., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-07-01
Release date:2005-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins.
Cell(Cambridge,Mass.), 122, 2005
2A69
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CRYSTAL STRUCTURE OF THE T. THERMOPHILUS RNA POLYMERASE HOLOENZYME IN COMPLEX WITH ANTIBIOTIC RIFAPENTIN
Descriptor:DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
Authors:Artsimovitch, I., Vassylyeva, M.N., Svetlov, D., Svetlov, V., Perederina, A., Igarashi, N., Matsugaki, N., Wakatsuki, S., Tahirov, T.H., Vassylyev, D.G., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-07-02
Release date:2005-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins.
Cell(Cambridge,Mass.), 122, 2005
2A6H
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CRYSTAL STRUCTURE OF THE T. THERMOPHILUS RNA POLYMERASE HOLOENZYME IN COMPLEX WITH ANTIBIOTIC STERPTOLYDIGIN
Descriptor:DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
Authors:Temiakov, D., Zenkin, N., Vassylyeva, M.N., Perederina, A., Tahirov, T.H., Savkina, M., Zorov, S., Nikiforov, V., Igarashi, N., Matsugaki, N., Wakatsuki, S., Severinov, K., Vassylyev, D.G., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-07-02
Release date:2005-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of transcription inhibition by antibiotic streptolydigin.
Mol.Cell, 19, 2005
2BE5
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CRYSTAL STRUCTURE OF THE T. THERMOPHILUS RNA POLYMERASE HOLOENZYME IN COMPLEX WITH INHIBITOR TAGETITOXIN
Descriptor:DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
Authors:Vassylyev, D.G., Svetlov, V., Vassylyeva, M.N., Perederina, A., Igarashi, N., Matsugaki, N., Wakatsuki, S., Artsimovitch, I., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-10-22
Release date:2005-11-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for transcription inhibition by tagetitoxin
Nat.Struct.Mol.Biol., 12, 2005
2EUL
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STRUCTURE OF THE TRANSCRIPTION FACTOR GFH1.
Descriptor:anti-cleavage anti-GreA transcription factor Gfh1, ZINC ION
Authors:Symersky, J., Perederina, A., Vassylyeva, M.N., Svetlov, V., Artsimovitch, I., Vassylyev, D.G., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-10-28
Release date:2005-11-15
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Regulation through the RNA Polymerase Secondary Channel: STRUCTURAL AND FUNCTIONAL VARIABILITY OF THE COILED-COIL TRANSCRIPTION FACTORS.
J.Biol.Chem., 281, 2006
2IPC
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CRYSTAL STRUCTURE OF THE TRANSLOCATION ATPASE SECA FROM THERMUS THERMOPHILUS REVEALS A PARALLEL, HEAD-TO-HEAD DIMER
Descriptor:Preprotein translocase SecA subunit
Authors:Vassylyev, D.G., Mori, H., Vassylyeva, M.N., Tsukazaki, T., Kimura, Y., Tahirov, T.H., Ito, K., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-10-12
Release date:2006-11-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of the Translocation ATPase SecA from Thermus thermophilus Reveals a Parallel, Head-to-Head Dimer.
J.Mol.Biol., 364, 2006
2O5I
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CRYSTAL STRUCTURE OF THE T. THERMOPHILUS RNA POLYMERASE ELONGATION COMPLEX
Descriptor:5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP*CP*GP*CP*CP*G)-3', 5'-R(P*GP*AP*GP*UP*CP*UP*GP*CP*GP*GP*CP*GP*CP*GP*CP*G)-3', 5'-D(*AP*AP*CP*GP*CP*CP*AP*GP*AP*CP*AP*GP*GP*G)-3', ...
Authors:Vassylyev, D.G., Tahirov, T.H., Vassylyeva, M.N.
Deposit date:2006-12-06
Release date:2007-07-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for transcription elongation by bacterial RNA polymerase.
Nature, 448, 2007
2O5J
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CRYSTAL STRUCTURE OF THE T. THERMOPHILUS RNAP POLYMERASE ELONGATION COMPLEX WITH THE NTP SUBSTRATE ANALOG
Descriptor:5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP*CP*GP*CP*CP*G)-3', 5'-R(P*GP*AP*GP*UP*CP*UP*GP*CP*GP*GP*CP*GP*CP*GP*CP*G)-3', 5'-D(*AP*AP*CP*GP*CP*CP*AP*GP*AP*CP*AP*GP*GP*G)-3', ...
Authors:Vassylyev, D.G., Vassylyeva, M.N.
Deposit date:2006-12-06
Release date:2007-07-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for substrate loading in bacterial RNA polymerase.
Nature, 448, 2007
2OUG
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CRYSTAL STRUCTURE OF THE RFAH TRANSCRIPTION FACTOR AT 2.1A RESOLUTION
Descriptor:Transcriptional activator rfaH
Authors:Vassylyev, D.G., Vassylyeva, M.N., Svetlov, V., Artsimovitch, I.
Deposit date:2007-02-10
Release date:2007-05-01
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for converting a general transcription factor into an operon-specific virulence regulator.
Mol.Cell, 26, 2007
2PPB
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CRYSTAL STRUCTURE OF THE T. THERMOPHILUS RNAP POLYMERASE ELONGATION COMPLEX WITH THE NTP SUBSTRATE ANALOG AND ANTIBIOTIC STREPTOLYDIGIN
Descriptor:DNA (5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP*CP*GP*CP*CP*G)-3'), RNA (5'-R(P*GP*AP*GP*UP*CP*UP*GP*CP*GP*GP*CP*GP*CP*GP*CP*G)-3'), DNA (5'-D(*AP*AP*CP*GP*CP*CP*AP*GP*AP*CP*AP*GP*GP*G)-3'), ...
Authors:Vassylyev, D.G., Vassylyeva, M.N., Artsimovitch, I., Landick, R.
Deposit date:2007-04-28
Release date:2007-07-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for substrate loading in bacterial RNA polymerase.
Nature, 448, 2007
3EQL
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CRYSTAL STRUCTURE OF THE T. THERMOPHILUS RNA POLYMERASE HOLOENZYME IN COMPLEX WITH ANTIBIOTIC MYXOPYRONIN
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Vassylyev, D.G., Vassylyeva, M.N., Artsimovitch, I.
Deposit date:2008-09-30
Release date:2008-10-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Transcription inactivation through local refolding of the RNA polymerase structure.
Nature, 457, 2009
1IW7
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CRYSTAL STRUCTURE OF THE RNA POLYMERASE HOLOENZYME FROM THERMUS THERMOPHILUS AT 2.6A RESOLUTION
Descriptor:RNA polymerase alpha subunit, RNA polymerase beta subunit, RNA polymerase omega subunit, ...
Authors:RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2002-04-22
Release date:2002-06-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of a bacterial RNA polymerase holoenzyme at 2.6 A resolution
NATURE, 417, 2002
5TMC
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RE-REFINEMENT OF THERMUS THERMOPILES DNA-DIRECTED RNA POLYMERASE STRUCTURE
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Wang, J.
Deposit date:2016-10-12
Release date:2016-11-23
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:On the validation of crystallographic symmetry and the quality of structures.
Protein Sci., 24, 2015