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2HQU
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HUMAN DUTPASE IN COMPLEX WITH ALPHA,BETA-IMINODUTP AND MAGNESIUM ION
Descriptor:Deoxyuridine 5'-triphosphate nucleotidohydrolase, MAGNESIUM ION, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, ...
Authors:Barabas, O., Varga, B., Vertessy, B.G.
Deposit date:2006-07-19
Release date:2007-07-24
Last modified:2016-10-19
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Active site closure facilitates juxtaposition of reactant atoms for initiation of catalysis by human dUTPase.
Febs Lett., 581, 2007
2PY4
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FULL LENGTH STRUCTURE OF THE MYCOBACTERIUM TUBERCULOSIS DUTPASE COMPLEXED WITH MAGNESIUM AND ALPHA,BETA-IMIDO-DUTP.
Descriptor:Deoxyuridine 5'-triphosphate nucleotidohydrolase, MAGNESIUM ION, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, ...
Authors:Barabas, O., Nagy, N., Takacs, E., Vertessy, B.G.
Deposit date:2007-05-15
Release date:2007-05-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Active site of mycobacterial dUTPase: structural characteristics and a built-in sensor.
Biochem.Biophys.Res.Commun., 373, 2008
2HR6
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CRYSTAL STRUCTURE OF DUTPASE IN COMPLEX WITH SUBSTRATE ANALOGUE DUDP AND MANGANESE
Descriptor:Deoxyuridine 5'-triphosphate nucleotidohydrolase, MANGANESE (II) ION, DEOXYURIDINE-5'-DIPHOSPHATE, ...
Authors:Barabas, O., Kovari, J., Tapai, R., Vertessy, B.G.
Deposit date:2006-07-19
Release date:2007-07-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Methylene substitution at the alpha-beta bridging position within the phosphate chain of dUDP profoundly perturbs ligand accommodation into the dUTPase active site.
Proteins, 71, 2008
2HRM
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CRYSTAL STRUCTURE OF DUTPASE COMPLEXED WITH SUBSTRATE ANALOGUE METHYLENE-DUTP
Descriptor:Deoxyuridine 5'-triphosphate nucleotidohydrolase, 2'-DEOXY-5'-O-[(S)-HYDROXY(PHOSPHONOMETHYL)PHOSPHORYL]URIDINE, 1,2-ETHANEDIOL
Authors:Barabas, O., Kovari, J., Tapai, R., Vertessy, B.G.
Deposit date:2006-07-20
Release date:2007-07-31
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Methylene substitution at the alpha-beta bridging position within the phosphate chain of dUDP profoundly perturbs ligand accommodation into the dUTPase active site.
Proteins, 71, 2008
3BG6
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PYRANOSE 2-OXIDASE FROM TRAMETES MULTICOLOR, E542K MUTANT
Descriptor:Pyranose oxidase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Tan, T.C., Divne, C.
Deposit date:2007-11-26
Release date:2008-12-02
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Improving thermostability and catalytic activity of pyranose 2-oxidase from Trametes multicolor by rational and semi-rational design
Febs J., 276, 2009
3BG7
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PYRANOSE 2-OXIDASE FROM TRAMETES MULTICOLOR, L537G MUTANT
Descriptor:Pyranose oxidase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Norberg, P., Tan, T.C., Divne, C.
Deposit date:2007-11-26
Release date:2008-12-02
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Improving thermostability and catalytic activity of pyranose 2-oxidase from Trametes multicolor by rational and semi-rational design
Febs J., 276, 2009
3BLY
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PYRANOSE 2-OXIDASE FROM TRAMETES MULTICOLOR, E542K/L537W
Descriptor:Pyranose oxidase, FLAVIN-ADENINE DINUCLEOTIDE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Tan, T.C., Divne, C.
Deposit date:2007-12-11
Release date:2008-12-02
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Improving thermostability and catalytic activity of pyranose 2-oxidase from Trametes multicolor by rational and semi-rational design
Febs J., 276, 2009
3EHW
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HUMAN DUTPASE IN COMPLEX WITH ALPHA,BETA-IMIDO-DUTP AND MG2+: VISUALIZATION OF THE FULL-LENGTH C-TERMINI IN ALL MONOMERS AND SUGGESTION FOR AN ADDITIONAL METAL ION BINDING SITE
Descriptor:dUTP pyrophosphatase, MAGNESIUM ION, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE
Authors:Takacs, E., Barabas, O., Vertessy, B.G.
Deposit date:2008-09-15
Release date:2008-09-30
Last modified:2012-03-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Human dUTPase in complex with alpha,beta-imido-dUTP and Mg2+: visualization of the full-length C-termini in all monomers and suggestion for an additional metal ion binding site
To be Published