Author results

1LCC
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STRUCTURE OF THE COMPLEX OF LAC REPRESSOR HEADPIECE AND AN 11 BASE-PAIR HALF-OPERATOR DETERMINED BY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND RESTRAINED MOLECULAR DYNAMICS
Descriptor:DNA (5'-D(*AP*AP*TP*TP*GP*TP*GP*AP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*T)-3'), Lac Repressor, ...
Authors:Chuprina, V.P., Rullmann, J.A.C., Lamerichs, R.M.J.N., Van Boom, J.H., Boelens, R., Kaptein, R.
Deposit date:1993-03-25
Release date:1994-01-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the complex of lac repressor headpiece and an 11 base-pair half-operator determined by nuclear magnetic resonance spectroscopy and restrained molecular dynamics.
J.Mol.Biol., 234, 1993
1LCD
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STRUCTURE OF THE COMPLEX OF LAC REPRESSOR HEADPIECE AND AN 11 BASE-PAIR HALF-OPERATOR DETERMINED BY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND RESTRAINED MOLECULAR DYNAMICS
Descriptor:DNA (5'-D(*AP*AP*TP*TP*GP*TP*GP*AP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*T)-3'), Lac Repressor, ...
Authors:Chuprina, V.P., Rullmann, J.A.C., Lamerichs, R.M.J.N., Van Boom, J.H., Boelens, R., Kaptein, R.
Deposit date:1993-03-25
Release date:1994-01-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the complex of lac repressor headpiece and an 11 base-pair half-operator determined by nuclear magnetic resonance spectroscopy and restrained molecular dynamics.
J.Mol.Biol., 234, 1993
1AU5
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SOLUTION STRUCTURE OF INTRASTRAND CISPLATIN-CROSSLINKED DNA OCTAMER D(CCTG*G*TCC):D(GGACCAGG), NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:DNA (5'-D(*CP*CP*TP*GP*GP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*CP*CP*AP*GP*G)-3'), Cisplatin
Authors:Yang, D., Van Boom, S.S.G.E., Reedijk, J., Van Boom, J.H., Wang, A.H.-J.
Deposit date:1997-09-11
Release date:1998-02-25
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure and isomerization of an intrastrand cisplatin-cross-linked octamer DNA duplex by NMR analysis.
Biochemistry, 34, 1995
1AU6
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SOLUTION STRUCTURE OF DNA D(CATGCATG) INTERSTRAND-CROSSLINKED BY BISPLATIN COMPOUND (1,1/T,T), NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:DNA (5'-D(*CP*AP*TP*GP*CP*AP*TP*G)-3'), BIS(TRANS-PLATINUM ETHYLENEDIAMINE DIAMINE CHLORO)COMPLEX
Authors:Yang, D., Van Boom, S.S.G.E., Reedijk, J., Van Boom, J.H., Farrell, N., Wang, A.H.-J.
Deposit date:1997-09-11
Release date:1998-02-25
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A novel DNA structure induced by the anticancer bisplatinum compound crosslinked to a GpC site in DNA.
Nat.Struct.Biol., 2, 1995
1NDN
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MOLECULAR STRUCTURE OF NICKED DNA. MODEL T4
Descriptor:DNA (5'-D(*CP*GP*CP*GP*AP*AP*AP*AP*CP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*GP*TP*T)-3'), DNA (5'-D(*TP*TP*CP*GP*CP*G)-3')
Authors:Aymani, J., Coll, M., Van Der Marel, G.A., Van Boom, J.H., Wang, A.H.-J., Rich, A.
Deposit date:1992-01-15
Release date:1992-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Molecular structure of nicked DNA: a substrate for DNA repair enzymes.
Proc.Natl.Acad.Sci.USA, 87, 1990
1VTE
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MOLECULAR STRUCTURE OF NICKED DNA. MODEL A4
Descriptor:DNA (5'-D(*CP*GP*CP*GP*AP*AP*AP*AP*CP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*GP*TP*T)-3'), DNA (5'-D(*TP*TP*CP*GP*CP*G)-3')
Authors:Aymani, J., Coll, M., Van Der Marel, G.A., Van Boom, J.H., Wang, A.H.-J., Rich, A.
Deposit date:1990-05-21
Release date:2011-07-13
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:Molecular structure of nicked DNA: a substrate for DNA repair enzymes.
Proc. Natl. Acad. Sci. U.S.A., 87, 1990
1VTG
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THE MOLECULAR STRUCTURE OF A DNA-TRIOSTIN A COMPLEX
Descriptor:DNA (5'-D(*CP*GP*TP*AP*CP*G)-3'), triostin A, 2-CARBOXYQUINOXALINE
Authors:Wang, A.H.-J., Ughetto, G., Quigley, G.J., Hakoshima, T., Van Der Marel, G.A., Van Boom, J.H., Rich, A.
Deposit date:1988-08-18
Release date:2011-07-13
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:The molecular structure of a DNA-triostin A complex.
Science, 225, 1984
264D
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THREE-DIMENSIONAL CRYSTAL STRUCTURE OF THE A-TRACT DNA DODECAMER D(CGCAAATTTGCG) COMPLEXED WITH THE MINOR-GROOVE-BINDING DRUG HOECHST 33258
Descriptor:DNA (5'-D(*CP*GP*CP*AP*AP*AP*TP*TP*TP*GP*CP*G)-3'), 2'-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE
Authors:Vega, M.C., Garcia-Saez, I., Aymami, J., Eritja, R., Van Der Marel, G.A., Van Boom, J.H., Rich, A., Coll, M.
Deposit date:1994-09-22
Release date:1995-03-31
Last modified:2016-12-14
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Three-dimensional crystal structure of the A-tract DNA dodecamer d(CGCAAATTTGCG) complexed with the minor-groove-binding drug Hoechst 33258.
Eur.J.Biochem., 222, 1994
1AC7
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STRUCTURAL FEATURES OF THE DNA HAIRPIN D(ATCCTAGTTATAGGAT): THE FORMATION OF A G-A BASE PAIR IN THE LOOP, NMR, 10 STRUCTURES
Descriptor:DNA (5'-D(*AP*TP*CP*CP*TP*AP*GP*TP*TP*AP*TP*AP*GP*GP*AP*T)-3')
Authors:Van Dongen, M.J.P., Mooren, M.M.W., Willems, E.F.A., Van Der Marel, G.A., Van Boom, J.H., Wijmenga, S.S., Hilbers, C.W.
Deposit date:1997-02-14
Release date:1997-07-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural features of the DNA hairpin d(ATCCTA-GTTA-TAGGAT): formation of a G-A base pair in the loop.
Nucleic Acids Res., 25, 1997
1B4Y
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STRUCTURE AND MECHANISM OF FORMATION OF THE H-Y5 ISOMER OF AN INTRAMOLECULAR DNA TRIPLE HELIX.
Descriptor:DNA (H-Y5 TRIPLE HELIX)
Authors:Van Dongen, M.J.P., Doreleijers, J.F., Van Der Marel, G.A., Van Boom, J.H., Hilbers, C.W., Wijmenga, S.S.
Deposit date:1998-12-30
Release date:1999-09-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure and mechanism of formation of the H-y5 isomer of an intramolecular DNA triple helix.
Nat.Struct.Biol., 6, 1999
1D96
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MOLECULAR STRUCTURE OF R(GCG)D(TATACGC): A DNA-RNA HYBRID HELIX JOINED TO DOUBLE HELICAL DNA
Descriptor:DNA/RNA (5'-R(*GP*CP*GP*)-D(*TP*AP*TP*AP*CP*GP*C)-3')
Authors:Wang, A.H.-J., Fujii, S., Van Boom, J.H., Van Der Marel, G.A., Van Boeckel, S.A.A., Rich, A.
Deposit date:1992-10-17
Release date:1993-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular structure of r(GCG)d(TATACGC): a DNA--RNA hybrid helix joined to double helical DNA.
Nature, 299, 1982
1UZ6
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ANTI-LEWIS X FAB FRAGMENT UNCOMPLEXED
Descriptor:IGG FAB (IGG3, KAPPA) LIGHT CHAIN 291-2G3-A, KAPPA) HEAVY CHAIN 291-2G3-A, ...
Authors:Van Roon, A.M.M., Pannu, N.S., De Vrind, J.P.M., Hokke, C.H., Deelder, A.M., Van Der marel, G.A., Van Boom, J.H., Abrahams, J.P.
Deposit date:2004-03-05
Release date:2004-06-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of an Anti-Lewis X Fab Fragment in Complex with its Lewis X Antigen
Structure, 12, 2004
1UZ8
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ANTI-LEWIS X FAB FRAGMENT IN COMPLEX WITH LEWIS X
Descriptor:IGG FAB (IGG3, KAPPA) LIGHT CHAIN 291-2G3-A, KAPPA) HEAVY CHAIN 291-2G3-A, ...
Authors:Van Roon, A.M.M., Pannu, N.S., De Vrind, J.P.M., Hokke, C.H., Deelder, A.M., Van Der marel, G.A., Van Boom, J.H., Abrahams, J.P.
Deposit date:2004-03-05
Release date:2004-06-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of an Anti-Lewis X Fab Fragment in Complex with its Lewis X Antigen
Structure, 12, 2004
121D
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MOLECULAR STRUCTURE OF THE A-TRACT DNA DODECAMER D(CGCAAATTTGCG) COMPLEXED WITH THE MINOR GROOVE BINDING DRUG NETROPSIN
Descriptor:DNA (5'-D(*CP*GP*CP*AP*AP*AP*TP*TP*TP*GP*CP*G)-3'), NETROPSIN
Authors:Tabernero, L., Verdaguer, N., Coll, M., Fita, I., Van Der Marel, G.A., Van Boom, J.H., Rich, A., Aymami, J.
Deposit date:1993-04-14
Release date:1994-01-15
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Molecular structure of the A-tract DNA dodecamer d(CGCAAATTTGCG) complexed with the minor groove binding drug netropsin.
Biochemistry, 32, 1993
127D
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DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3') COMPLEXED WITH HOECHST 33258
Descriptor:DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), 2'-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE
Authors:Sriram, M., Van Der Marel, G.A., Roelen, H.L.P.F., Van Boom, J.H., Wang, A.H.-J.
Deposit date:1993-06-30
Release date:1994-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conformation of B-DNA containing O6-ethyl-G-C base pairs stabilized by minor groove binding drugs: molecular structure of d(CGC[e6G]AATTCGCG complexed with Hoechst 33258 or Hoechst 33342.
EMBO J., 11, 1992
128D
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MOLECULAR STRUCTURE OF D(CGC[E6G]AATTCGCG) COMPLEXED WITH HOECHST 33258
Descriptor:DNA (5'-D(*CP*GP*CP*(G36)P*AP*AP*TP*TP*CP*GP*CP*G)-3'), 2'-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE
Authors:Sriram, M., Van Der Marel, G.A., Roelen, H.L.P.F., Van Boom, J.H., Wang, A.H.-J.
Deposit date:1993-06-30
Release date:1994-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Conformation of B-DNA containing O6-ethyl-G-C base pairs stabilized by minor groove binding drugs: molecular structure of d(CGC[e6G]AATTCGCG complexed with Hoechst 33258 or Hoechst 33342.
EMBO J., 11, 1992
129D
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DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3') COMPLEXED WITH HOECHST 33342
Descriptor:DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), 2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE
Authors:Sriram, M., Van Der Marel, G.A., Roelen, H.L.P.F., Van Boom, J.H., Wang, A.H.-J.
Deposit date:1993-06-30
Release date:1994-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Conformation of B-DNA containing O6-ethyl-G-C base pairs stabilized by minor groove binding drugs: molecular structure of d(CGC[e6G]AATTCGCG complexed with Hoechst 33258 or Hoechst 33342.
EMBO J., 11, 1992
130D
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MOLECULAR STRUCTURE OF D(CGC[E6G]AATTCGCG) COMPLEXED WITH HOECHST 33342
Descriptor:DNA (5'-D(*CP*GP*CP*(G36)P*AP*AP*TP*TP*CP*GP*CP*G)-3'), 2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE
Authors:Sriram, M., Van Der Marel, G.A., Roelen, H.L.P.F., Van Boom, J.H., Wang, A.H.-J.
Deposit date:1993-06-30
Release date:1994-01-15
Last modified:2011-08-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Conformation of B-DNA containing O6-ethyl-G-C base pairs stabilized by minor groove binding drugs: molecular structure of d(CGC[e6G]AATTCGCG complexed with Hoechst 33258 or Hoechst 33342.
EMBO J., 11, 1992
1D10
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STRUCTURAL COMPARISON OF ANTICANCER DRUG-DNA COMPLEXES. ADRIAMYCIN AND DAUNOMYCIN
Descriptor:DNA (5'-D(*CP*GP*AP*TP*CP*G)-3'), DAUNOMYCIN, SPERMINE, ...
Authors:Frederick, C.A., Williams, L.D., Ughetto, G., Van Der Marel, G.A., Van Boom, J.H., Rich, A., Wang, A.H.-J.
Deposit date:1989-10-20
Release date:1990-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural comparison of anticancer drug-DNA complexes: adriamycin and daunomycin.
Biochemistry, 29, 1990
1D12
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STRUCTURAL COMPARISON OF ANTICANCER DRUG-DNA COMPLEXES. ADRIAMYCIN AND DAUNOMYCIN
Descriptor:DNA (5'-D(*CP*GP*AP*TP*CP*G)-3'), DOXORUBICIN, SPERMINE, ...
Authors:Frederick, C.A., Williams, L.D., Ughetto, G., Van Der Marel, G.A., Van Boom, J.H., Rich, A., Wang, A.H.-J.
Deposit date:1989-10-20
Release date:1990-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural comparison of anticancer drug-DNA complexes: adriamycin and daunomycin.
Biochemistry, 29, 1990
1D13
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MOLECULAR STRUCTURE OF AN A-DNA DECAMER D(ACCGGCCGGT)
Descriptor:DNA (5'-D(*AP*CP*CP*GP*GP*CP*CP*GP*GP*T)-3')
Authors:Frederick, C.A., Quigley, G.J., Teng, M.-K., Coll, M., Van Der Marel, G.A., Van Boom, J.H., Rich, A., Wang, A.H.-J.
Deposit date:1989-10-20
Release date:1990-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular structure of an A-DNA decamer d(ACCGGCCGGT).
Eur.J.Biochem., 181, 1989
1D14
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STRUCTURE OF 11-DEOXYDAUNOMYCIN BOUND TO DNA CONTAINING A PHOSPHOROTHIOATE
Descriptor:DNA (5'-D(*CP*GP*TP*(AS)P*CP*G)-3'), 6-DEOXYDAUNOMYCIN
Authors:Williams, L.D., Egli, M., Ughetto, G., Van Der Marel, G.A., Van Boom, J.H., Quigley, G.J., Wang, A.H.-J., Rich, A., Frederick, C.A.
Deposit date:1989-10-20
Release date:1990-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of 11-deoxydaunomycin bound to DNA containing a phosphorothioate.
J.Mol.Biol., 215, 1990
1D35
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FACILE FORMATION OF A CROSSLINKED ADDUCT BETWEEN DNA AND THE DAUNORUBICIN DERIVATIVE MAR70 MEDIATED BY FORMALDEHYDE: MOLECULAR STRUCTURE OF THE MAR70-D(CGTNACG) COVALENT ADDUC
Descriptor:DNA (5'-D(*CP*GP*TP*(A40)P*CP*G)-3'), 4'-EPI-4'-(2-DEOXYFUCOSE)DAUNOMYCIN, MAGNESIUM ION
Authors:Gao, Y.-G., Liaw, Y.-C., Li, Y.-K., Van Der Marel, G.A., Van Boom, J.H., Wang, A.H.-J.
Deposit date:1991-04-23
Release date:1992-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Facile formation of a crosslinked adduct between DNA and the daunorubicin derivative MAR70 mediated by formaldehyde: molecular structure of the MAR70-d(CGTnACG) covalent adduct.
Proc.Natl.Acad.Sci.USA, 88, 1991
1D36
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FACILE FORMATION OF A CROSSLINKED ADDUCT BETWEEN DNA AND THE DAUNORUBICIN DERIVATIVE MAR70 MEDIATED BY FORMALDEHYDE: MOLECULAR STRUCTURE OF THE MAR70-D(CGTNACG) COVALENT ADDUC
Descriptor:DNA (5'-D(*CP*GP*TP*AP*CP*G)-3'), 4'-EPI-4'-(2-DEOXYFUCOSE)DAUNOMYCIN, MAGNESIUM ION
Authors:Gao, Y.-G., Liaw, Y.-C., Li, Y.-K., Van Der Marel, G.A., Van Boom, J.H., Wang, A.H.-J.
Deposit date:1991-04-23
Release date:1992-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Facile formation of a crosslinked adduct between DNA and the daunorubicin derivative MAR70 mediated by formaldehyde: molecular structure of the MAR70-d(CGTnACG) covalent adduct.
Proc.Natl.Acad.Sci.USA, 88, 1991
1D85
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STRUCTURAL CONSEQUENCES OF A CARCINOGENIC ALKYLATION LESION ON DNA: EFFECT OF O6-ETHYL-GUANINE ON THE MOLECULAR STRUCTURE OF D(CGC[E6G]AATTCGCG)-NETROPSIN COMPLEX
Descriptor:DNA (5'-D(*CP*GP*CP*(G36)P*AP*AP*TP*TP*CP*GP*CP*G)-3'), NETROPSIN
Authors:Sriram, M., Van Der Marel, G.A., Roelen, H.L.P.F., Van Boom, J.H., Wang, A.H.-J.
Deposit date:1992-08-24
Release date:1993-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural consequences of a carcinogenic alkylation lesion on DNA: effect of O6-ethylguanine on the molecular structure of the d(CGC[e6G]AATTCGCG)-netropsin complex.
Biochemistry, 31, 1992