Author results

1MLV
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STRUCTURE AND CATALYTIC MECHANISM OF A SET DOMAIN PROTEIN METHYLTRANSFERASE
Descriptor:Ribulose-1,5 biphosphate carboxylase/oxygenase large subunit N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Trievel, R.C., Beach, B.M., Dirk, L.M.A., Houtz, R.L., Hurley, J.H.
Deposit date:2002-08-30
Release date:2002-10-30
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure and catalytic mechanism of a SET domain protein methyltransferase.
Cell(Cambridge,Mass.), 111, 2002
1OZV
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CRYSTAL STRUCTURE OF THE SET DOMAIN OF LSMT BOUND TO LYSINE AND ADOHCY
Descriptor:Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast, LYSINE, ...
Authors:Trievel, R.C., Flynn, E.M., Houtz, R.L., Hurley, J.H.
Deposit date:2003-04-09
Release date:2003-07-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Mechanism of multiple lysine methylation by the SET domain enzyme Rubisco LSMT
Nat.Struct.Biol., 10, 2003
1P0Y
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CRYSTAL STRUCTURE OF THE SET DOMAIN OF LSMT BOUND TO MELYSINE AND ADOHCY
Descriptor:Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Trievel, R.C., Flynn, E.M., Houtz, R.L., Hurley, J.H.
Deposit date:2003-04-11
Release date:2003-07-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Mechanism of multiple lysine methylation by the SET domain enzyme Rubisco LSMT
Nat.Struct.Biol., 10, 2003
1YGH
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HAT DOMAIN OF GCN5 FROM SACCHAROMYCES CEREVISIAE
Descriptor:PROTEIN (TRANSCRIPTIONAL ACTIVATOR GCN5), GLYCEROL
Authors:Trievel, R.C., Rojas, J.R., Sterner, D.E., Venkataramani, R., Wang, L., Zhou, J., Allis, C.D., Berger, S.L., Marmorstein, R.
Deposit date:1999-05-27
Release date:1999-08-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure and mechanism of histone acetylation of the yeast GCN5 transcriptional coactivator.
Proc.Natl.Acad.Sci.USA, 96, 1999
1CM0
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CRYSTAL STRUCTURE OF THE PCAF/COENZYME-A COMPLEX
Descriptor:P300/CBP ASSOCIATING FACTOR, COENZYME A
Authors:Clements, A., Rojas, J.R., Trievel, R.C., Wang, L., Berger, S.L., Marmorstein, R.
Deposit date:1999-05-12
Release date:1999-07-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the histone acetyltransferase domain of the human PCAF transcriptional regulator bound to coenzyme A.
EMBO J., 18, 1999
1QSN
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CRYSTAL STRUCTURE OF TETRAHYMENA GCN5 WITH BOUND COENZYME A AND HISTONE H3 PEPTIDE
Descriptor:TGCN5 HISTONE ACETYL TRANSFERASE, HISTONE H3, COENZYME A
Authors:Rojas, J.R., Trievel, R.C., Zhou, J., Mo, Y., Li, X., Berger, S.L., David Allis, C., Marmorstein, R.
Deposit date:1999-06-22
Release date:1999-09-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide.
Nature, 401, 1999
1QSR
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CRYSTAL STRUCTURE OF TETRAHYMENA GCN5 WITH BOUND ACETYL-COENZYME A
Descriptor:TGCN5 HISTONE ACETYL TRANSFERASE, ACETYL COENZYME *A
Authors:Rojas, J.R., Trievel, R.C., Zhou, J., Mo, Y., Li, X., Berger, S.L., David Allis, C., Marmorstein, R.
Deposit date:1999-06-23
Release date:1999-09-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide.
Nature, 401, 1999
1QST
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CRYSTAL STRUCTURE OF TETRAHYMENA GCN5
Descriptor:TGCN5 HISTONE ACETYL TRANSFERASE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Rojas, J.R., Trievel, R.C., Zhou, J., Mo, Y., Li, X., Berger, S.L., David Allis, C., Marmorstein, R.
Deposit date:1999-06-23
Release date:1999-09-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide.
Nature, 401, 1999
1ZKK
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CRYSTAL STRUCTURE OF HSET8 IN TERNARY COMPLEX WITH H4 PEPTIDE (16-24) AND ADOHCY
Descriptor:Histone-lysine N-methyltransferase, H4 lysine-20 specific, Peptide corresponding to residues 15-24 of histone H4, ...
Authors:Couture, J.-F., Collazo, E., Brunzelle, J.S., Trievel, R.C.
Deposit date:2005-05-03
Release date:2005-06-07
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural and functional analysis of SET8, a histone H4 Lys-20 methyltransferase
Genes Dev., 19, 2005
2F69
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TERNARY COMPLEX OF SET7/9 BOUND TO ADOHCY AND A TAF10 PEPTIDE
Descriptor:Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7, TAF10 peptide, ...
Authors:Couture, J.-F., Collazo, E., Hauk, G., Trievel, R.C.
Deposit date:2005-11-28
Release date:2006-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural basis for the methylation site specificity of SET7/9
Nat.Struct.Mol.Biol., 13, 2006
2H13
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CRYSTAL STRUCTURE OF WDR5/HISTONE H3 COMPLEX
Descriptor:WD-repeat protein 5, histone H3 lys-4 dimethylated
Authors:Couture, J.F., Collazo, E., Trievel, R.C.
Deposit date:2006-05-15
Release date:2006-07-11
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Molecular recognition of histone H3 by the WD40 protein WDR5.
Nat.Struct.Mol.Biol., 13, 2006
2H14
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CRYSTAL OF WDR5 (APO-FORM)
Descriptor:WD-repeat protein 5
Authors:Couture, J.F., Collazo, E., Trievel, R.C.
Deposit date:2006-05-15
Release date:2006-07-11
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Molecular recognition of histone H3 by the WD40 protein WDR5.
Nat.Struct.Mol.Biol., 13, 2006
2H21
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STRUCTURE OF RUBISCO LSMT BOUND TO ADOMET
Descriptor:Ribulose-1,5 bisphosphate carboxylase/oxygenase, S-ADENOSYLMETHIONINE
Authors:Couture, J.F., Hauk, G., Trievel, R.C.
Deposit date:2006-05-17
Release date:2006-05-30
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Catalytic Roles for Carbon-Oxygen Hydrogen Bonding in SET Domain Lysine Methyltransferases.
J.Biol.Chem., 281, 2006
2H23
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STRUCTURE OF RUBISCO LSMT BOUND TO TRIMETHYLLYSINE AND ADOHCY
Descriptor:Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, N-TRIMETHYLLYSINE
Authors:Couture, J.F., Hauk, G., Trievel, R.C.
Deposit date:2006-05-17
Release date:2006-05-30
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Catalytic Roles for Carbon-Oxygen Hydrogen Bonding in SET Domain Lysine Methyltransferases.
J.Biol.Chem., 281, 2006
2H2E
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STRUCTURE OF RUBISCO LSMT BOUND TO AZAADOMET AND LYSINE
Descriptor:Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, S-5'-AZAMETHIONINE-5'-DEOXYADENOSINE, LYSINE
Authors:Couture, J.F., Hauk, G., Trievel, R.C.
Deposit date:2006-05-18
Release date:2006-05-30
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Catalytic Roles for Carbon-Oxygen Hydrogen Bonding in SET Domain Lysine Methyltransferases.
J.Biol.Chem., 281, 2006
2H2J
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STRUCTURE OF RUBISCO LSMT BOUND TO SINEFUNGIN AND MONOMETHYLLYSINE
Descriptor:Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, SINEFUNGIN, N-METHYL-LYSINE
Authors:Couture, J.F., Hauk, G., Trievel, R.C.
Deposit date:2006-05-18
Release date:2006-05-30
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Catalytic Roles for Carbon-Oxygen Hydrogen Bonding in SET Domain Lysine Methyltransferases.
J.Biol.Chem., 281, 2006
2Q8C
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CRYSTAL STRUCTURE OF JMJD2A IN TERNARY COMPLEX WITH AN HISTONE H3K9ME3 PEPTIDE AND 2-OXOGLUTARATE
Descriptor:JmjC domain-containing histone demethylation protein 3A, HISTONE 3 PEPTIDE, NICKEL (II) ION, ...
Authors:Couture, J.-F., Collazo, E., Ortiz-Tello, P., Brunzelle, J.S., Trievel, R.C.
Deposit date:2007-06-10
Release date:2007-07-03
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.047 Å)
Cite:Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase.
Nat.Struct.Mol.Biol., 14, 2007
2Q8D
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CRYSTAL STRUCTURE OF JMJ2D2A IN TERNARY COMPLEX WITH HISTONE H3-K36ME2 AND SUCCINATE
Descriptor:JmjC domain-containing histone demethylation protein 3A, HISTONE 3 peptide, NICKEL (II) ION, ...
Authors:Couture, J.-F., Collazo, E., Ortiz-Tello, P., Brunzelle, J.S., Trievel, R.C.
Deposit date:2007-06-10
Release date:2007-07-03
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase.
Nat.Struct.Mol.Biol., 14, 2007
2Q8E
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SPECIFICITY AND MECHANISM OF JMJD2A, A TRIMETHYLLYSINE-SPECIFIC HISTONE DEMETHYLASE
Descriptor:JmjC domain-containing histone demethylation protein 3A, histone 3 peptide, NICKEL (II) ION, ...
Authors:Couture, J.-F., Collazo, E., Ortiz-Tello, P., Brunzelle, J.S., Trievel, R.C.
Deposit date:2007-06-10
Release date:2007-07-03
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase.
Nat.Struct.Mol.Biol., 14, 2007
3F9W
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STRUCTURAL INSIGHTS INTO LYSINE MULTIPLE METHYLATION BY SET DOMAIN METHYLTRANSFERASES, SET8-Y334F / H4-LYS20 / ADOHCY
Descriptor:Histone-lysine N-methyltransferase SETD8, Histone H4, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Couture, J.-F., Dirk, L.M.A., Brunzelle, J.S., Houtz, R.L., Trievel, R.C.
Deposit date:2008-11-14
Release date:2008-11-25
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural origins for the product specificity of SET domain protein methyltransferases.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3F9X
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STRUCTURAL INSIGHTS INTO LYSINE MULTIPLE METHYLATION BY SET DOMAIN METHYLTRANSFERASES, SET8-Y334F / H4-LYS20ME2 / ADOHCY
Descriptor:Histone-lysine N-methyltransferase SETD8, Histone H4, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Couture, J.-F., Dirk, L.M.A., Brunzelle, J.S., Houtz, R.L., Trievel, R.C.
Deposit date:2008-11-14
Release date:2008-11-25
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Structural origins for the product specificity of SET domain protein methyltransferases.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3F9Y
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STRUCTURAL INSIGHTS INTO LYSINE MULTIPLE METHYLATION BY SET DOMAIN METHYLTRANSFERASES, SET8-Y334F / H4-LYS20ME1 / ADOHCY
Descriptor:Histone-lysine N-methyltransferase SETD8, Histone H4, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Couture, J.-F., Dirk, L.M.A., Brunzelle, J.S., Houtz, R.L., Trievel, R.C.
Deposit date:2008-11-14
Release date:2008-11-25
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural origins for the product specificity of SET domain protein methyltransferases.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3F9Z
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STRUCTURAL INSIGHTS INTO LYSINE MULTIPLE METHYLATION BY SET DOMAIN METHYLTRANSFERASES, SET8-Y245F / H4-LYS20 / ADOHCY
Descriptor:Histone-lysine N-methyltransferase SETD8, Histone H4, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Couture, J.-F., Dirk, L.M.A., Brunzelle, J.S., Houtz, R.L., Trievel, R.C.
Deposit date:2008-11-14
Release date:2008-11-25
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural origins for the product specificity of SET domain protein methyltransferases.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3IVS
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HOMOCITRATE SYNTHASE LYS4
Descriptor:Homocitrate synthase, mitochondrial, COBALT (II) ION, ...
Authors:Bulfer, S.L., Scott, E.M., Couture, J.-F., Pillus, L., Trievel, R.C.
Deposit date:2009-09-01
Release date:2009-09-22
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Crystal structure and functional analysis of homocitrate synthase, an essential enzyme in lysine biosynthesis.
J.Biol.Chem., 284, 2009
3IVT
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HOMOCITRATE SYNTHASE LYS4 BOUND TO 2-OG
Descriptor:Homocitrate synthase, mitochondrial, ZINC ION, ...
Authors:Bulfer, S.L., Scott, E.M., Couture, J.-F., Pillus, L., Trievel, R.C.
Deposit date:2009-09-01
Release date:2009-09-22
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Crystal structure and functional analysis of homocitrate synthase, an essential enzyme in lysine biosynthesis.
J.Biol.Chem., 284, 2009
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