3M53
SET7/9 in complex with TAF10 peptide and AdoHcy
Summary for 3M53
Entry DOI | 10.2210/pdb3m53/pdb |
Related | 2F69 3M54 3M55 3M56 3M57 3M58 3M59 3M5A |
Descriptor | Histone-lysine N-methyltransferase SETD7, TAF10 peptide, S-ADENOSYL-L-HOMOCYSTEINE, ... (4 entities in total) |
Functional Keywords | ternary complex, set domain, methyltransferase, s-adenosyl-l-homocysteine, taf10 peptide, chromatin regulator, chromosomal protein, nucleus, s-adenosyl-l-methionine, transcription, transcription regulation, transferase |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q8WTS6 |
Total number of polymer chains | 2 |
Total formula weight | 30683.21 |
Authors | Del Rizzo, P.A.,Couture, J.-F.,Roiko, M.S.,Strunk, B.S.,Brunzelle, J.S.,Dirk, L.M.,Houtz, R.L.,Trievel, R.C. (deposition date: 2010-03-12, release date: 2010-07-28, Last modification date: 2023-09-06) |
Primary citation | Del Rizzo, P.A.,Couture, J.F.,Dirk, L.M.,Strunk, B.S.,Roiko, M.S.,Brunzelle, J.S.,Houtz, R.L.,Trievel, R.C. SET7/9 catalytic mutants reveal the role of active site water molecules in lysine multiple methylation. J.Biol.Chem., 285:31849-31858, 2010 Cited by PubMed: 20675860DOI: 10.1074/jbc.M110.114587 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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