Author results

3EHW
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HUMAN DUTPASE IN COMPLEX WITH ALPHA,BETA-IMIDO-DUTP AND MG2+: VISUALIZATION OF THE FULL-LENGTH C-TERMINI IN ALL MONOMERS AND SUGGESTION FOR AN ADDITIONAL METAL ION BINDING SITE
Descriptor:dUTP pyrophosphatase, MAGNESIUM ION, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE
Authors:Takacs, E., Barabas, O., Vertessy, B.G.
Deposit date:2008-09-15
Release date:2008-09-30
Last modified:2012-03-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Human dUTPase in complex with alpha,beta-imido-dUTP and Mg2+: visualization of the full-length C-termini in all monomers and suggestion for an additional metal ion binding site
To be Published
3ECY
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CRYSTAL STRUCTURAL ANALYSIS OF DROSOPHILA MELANOGASTER DUTPASE
Descriptor:CG4584-PA, isoform A (BcDNA.LD08534)
Authors:Takacs, E., Barabas, O., Vertessy, B.G.
Deposit date:2008-09-02
Release date:2008-10-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Molecular shape and prominent role of beta-strand swapping in organization of dUTPase oligomers.
Febs Lett., 583, 2009
3H6D
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STRUCTURE OF THE MYCOBACTERIUM TUBERCULOSIS DUTPASE D28N MUTANT
Descriptor:Deoxyuridine 5'-triphosphate nucleotidohydrolase, MAGNESIUM ION, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, ...
Authors:Leveles, I., Harmat, V., Nagy, G., Takacs, E., Lopata, A., Toth, J., Vertessy, B.G.
Deposit date:2009-04-23
Release date:2009-11-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Direct contacts between conserved motifs of different subunits provide major contribution to active site organization in human and mycobacterial dUTPases.
Febs Lett., 584, 2010
2PY4
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FULL LENGTH STRUCTURE OF THE MYCOBACTERIUM TUBERCULOSIS DUTPASE COMPLEXED WITH MAGNESIUM AND ALPHA,BETA-IMIDO-DUTP.
Descriptor:Deoxyuridine 5'-triphosphate nucleotidohydrolase, MAGNESIUM ION, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, ...
Authors:Barabas, O., Nagy, N., Takacs, E., Vertessy, B.G.
Deposit date:2007-05-15
Release date:2007-05-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Active site of mycobacterial dUTPase: structural characteristics and a built-in sensor.
Biochem.Biophys.Res.Commun., 373, 2008
3I93
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS DUTPASE STOP138T MUTANT
Descriptor:Deoxyuridine 5'-triphosphate nucleotidohydrolase, MAGNESIUM ION, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, ...
Authors:Leveles, I., Harmat, V., Lopata, A., Toth, J., Vertessy, B.G.
Deposit date:2009-07-10
Release date:2009-11-24
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Direct contacts between conserved motifs of different subunits provide major contribution to active site organization in human and mycobacterial dUTPases.
Febs Lett., 584, 2010
4MZ5
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STRUCTURE OF IMPORTIN-ALPHA: DUTPASE NLS COMPLEX
Descriptor:Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, Importin subunit alpha-1
Authors:Marfori, M., Rona, G., Vertessy, B.G., Kobe, B.
Deposit date:2013-09-29
Release date:2013-11-13
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insights.
Acta Crystallogr.,Sect.D, 69, 2013
4MZ6
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STRUCTURE OF IMPORTIN-ALPHA: DUTPASE S11E NLS MUTANT COMPLEX
Descriptor:Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, Importin subunit alpha-1
Authors:Marfori, M., Rona, G., Vertessy, B.G., Kobe, B.
Deposit date:2013-09-29
Release date:2013-11-13
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insights.
Acta Crystallogr.,Sect.D, 69, 2013