7R6V
 
 | | Human EXOG complexed with dRP-containing DNA | | Descriptor: | DNA (5'-D(*CP*GP*CP*AP*CP*GP*TP*CP*AP*GP*AP*A)-3'), DNA (5'-D(*CP*TP*GP*AP*CP*GP*TP*GP*CP*G)-3'), MAGNESIUM ION, ... | | Authors: | Szymanski, M.R, Yin, Y.W. | | Deposit date: | 2021-06-23 | | Release date: | 2022-08-24 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.16 Å) | | Cite: | Human EXOG possesses strong AP hydrolysis activity
To Be Published
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7R6T
 | | Human EXOG complexed with dRP-containing DNA | | Descriptor: | DNA (5'-D(*CP*GP*CP*AP*CP*GP*TP*CP*AP*GP*A)-3'), DNA (5'-D(3DR)P*CP*TP*GP*AP*CP*GP*TP*GP*C)-3'), MAGNESIUM ION, ... | | Authors: | Szymanski, M.R, Yin, Y.W. | | Deposit date: | 2021-06-23 | | Release date: | 2022-08-24 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Human EXOG possesses strong AP hydrolysis activity
To Be Published
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4ZTU
 | | Structural basis for processivity and antiviral drug toxicity in human mitochondrial DNA replicase | | Descriptor: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (25-MER), DNA (5'-D(P*AP*AP*GP*AP*CP*GP*AP*GP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*GP*TP*AP*C)-3'), ... | | Authors: | Szymanski, M.R, Kuznestov, V.B, Shumate, C.K, Meng, Q, Lee, Y.-S, Patel, G, Patel, S.S, Yin, Y.W. | | Deposit date: | 2015-05-15 | | Release date: | 2015-09-23 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (3.299 Å) | | Cite: | Structural basis for processivity and antiviral drug toxicity
in human mitochondrial DNA replicase
EMBO J., 34, 2015
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4ZTZ
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5T4I
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5T5C
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5T3V
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5T40
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5C51
 | | Probing the Structural and Molecular Basis of Nucleotide Selectivity by Human Mitochondrial DNA Polymerase gamma | | Descriptor: | DNA, DNA (5'-D(*(AD)P*AP*AP*AP*CP*GP*AP*GP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*GP*TP*AP*C)-3'), DNA polymerase subunit gamma-1, ... | | Authors: | Sohl, C.D, Szymanski, M.R, Mislak, A.C, Shumate, C.K, Amiralaei, S, Schinazi, R.F, Anderson, K.S, Whitney, Y.Y. | | Deposit date: | 2015-06-19 | | Release date: | 2016-05-11 | | Last modified: | 2016-05-18 | | Method: | X-RAY DIFFRACTION (3.426 Å) | | Cite: | Probing the structural and molecular basis of nucleotide selectivity by human mitochondrial DNA polymerase gamma.
Proc.Natl.Acad.Sci.USA, 112, 2015
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5C52
 | | Probing the Structural and Molecular Basis of Nucleotide Selectivity by Human Mitochondrial DNA Polymerase gamma | | Descriptor: | DNA (26-MER), DNA (5'-D(*AP*AP*AP*AP*CP*GP*AP*GP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*GP*TP*AP*C)-3'), DNA polymerase subunit gamma-1, ... | | Authors: | Sohl, C.D, Szymanski, M.R, Mislak, A.C, Shumate, C.K, Amiralaei, S, Schinazi, R.F, Anderson, K.S, Yin, Y.W. | | Deposit date: | 2015-06-19 | | Release date: | 2016-05-11 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (3.637 Å) | | Cite: | Probing the structural and molecular basis of nucleotide selectivity by human mitochondrial DNA polymerase gamma.
Proc.Natl.Acad.Sci.USA, 112, 2015
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5C53
 | | Probing the Structural and Molecular Basis of Nucleotide Selectivity by Human Mitochondrial DNA Polymerase gamma | | Descriptor: | 2',3'-DIDEOXYCYTIDINE-5'-MONOPHOSPHATE, DNA (26-MER), DNA (5'-D(*AP*AP*AP*AP*CP*GP*AP*GP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*GP*TP*AP*C)-3'), ... | | Authors: | Sohl, C.D, Szymanski, M.R, Mislak, A.C, Shumate, C.K, Amiralaei, S, Schinazi, R.F, Anderson, K.S, Yin, Y.W. | | Deposit date: | 2015-06-19 | | Release date: | 2016-01-27 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (3.567 Å) | | Cite: | Probing the structural and molecular basis of nucleotide selectivity by human mitochondrial DNA polymerase gamma.
Proc.Natl.Acad.Sci.USA, 112, 2015
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