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1HEZ
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BU of 1hez by Molmil
Structure of P. magnus protein L bound to a human IgM Fab.
Descriptor: HEAVY CHAIN OF IG, IMIDAZOLE, KAPPA LIGHT CHAIN OF IG, ...
Authors:Graille, M, Stura, E.A, Housden, N.G, Bottomley, S.P, Taussig, M.J, Sutton, B.J, Gore, M.G, Charbonnier, J.B.
Deposit date:2000-11-27
Release date:2001-08-10
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Complex between Peptostreptococcus Magnus Protein L and a Human Antibody Reveals Structural Convergence in the Interaction Modes of Fab Binding Modes
Structure, 9, 2001
1QOK
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BU of 1qok by Molmil
MFE-23 AN ANTI-CARCINOEMBRYONIC ANTIGEN SINGLE-CHAIN FV ANTIBODY
Descriptor: MFE-23 RECOMBINANT ANTIBODY FRAGMENT
Authors:Boehm, M.K, Corper, A.L, Wan, T, Sohi, M.K, Sutton, B.J, Thornton, J.D, Keep, P.A, Chester, K.A, Begent, R.H.J, Perkins, S.J.
Deposit date:1999-11-11
Release date:2000-11-10
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of the Anti-Carcinoembryonic Antigen Single-Chain Fv Antibody Mfe-23 and a Model for Antigen Binding Based on Intermolecular Contacts
Biochem.J., 346, 2000
4D2N
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BU of 4d2n by Molmil
Crystal structure of deglycosylated serum-derived human IgG4 Fc
Descriptor: GLYCEROL, IG GAMMA-4 CHAIN C REGION
Authors:Davies, A.M, Jefferis, R, Sutton, B.J.
Deposit date:2014-05-12
Release date:2014-07-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of Deglycosylated Human Igg4-Fc
Mol.Immunol., 62, 2014
6EYO
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BU of 6eyo by Molmil
Structure of extended IgE-Fc in complex with two anti-IgE Fabs
Descriptor: 8D6 Fab heavy chain, 8D6 Fab light chain, Immunoglobulin heavy constant epsilon, ...
Authors:Chen, J.B, Ramadani, F, Pang, M.O.Y, Beavil, R.L, Holdom, M.D, Mitropoulou, A.N, Beavil, A.J, Gould, H.J, Chang, T.W, Sutton, B.J, McDonnell, J.M, Davies, A.M.
Deposit date:2017-11-13
Release date:2018-08-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Structural basis for selective inhibition of immunoglobulin E-receptor interactions by an anti-IgE antibody.
Sci Rep, 8, 2018
6EYN
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BU of 6eyn by Molmil
Structure of the 8D6 (anti-IgE) Fab
Descriptor: 1,2-ETHANEDIOL, 8D6 Fab heavy chain, 8D6 Fab light chain, ...
Authors:Chen, J.B, Ramadani, F, Pang, M.O.Y, Beavil, R.L, Holdom, M.D, Mitropoulou, A.N, Beavil, A.J, Gould, H.J, Chang, T.W, Sutton, B.J, McDonnell, J.M, Davies, A.M.
Deposit date:2017-11-13
Release date:2018-08-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for selective inhibition of immunoglobulin E-receptor interactions by an anti-IgE antibody.
Sci Rep, 8, 2018
5MOJ
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BU of 5moj by Molmil
Crystal structure of IgE-Fc epsilon 3-4
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Ig epsilon chain C region, ...
Authors:Dore, K.A, Davies, A.M, Drinkwater, N, Beavil, A.J, MacDonnell, J.M, Sutton, B.J.
Deposit date:2016-12-14
Release date:2018-01-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Thermal sensitivity and flexibility of the C epsilon 3 domains in immunoglobulin E.
Biochim. Biophys. Acta, 1865, 2017
5MOI
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BU of 5moi by Molmil
Crystal structure of human IgE-Fc epsilon 3-4
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Ig epsilon chain C region, ...
Authors:Dore, K.A, Davies, A.M, Drinkwater, N, Beavil, A.J, McDonnell, J.M, Sutton, B.J.
Deposit date:2016-12-14
Release date:2018-01-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Thermal sensitivity and flexibility of the C epsilon 3 domains in immunoglobulin E.
Biochim. Biophys. Acta, 1865, 2017
2Y7Q
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BU of 2y7q by Molmil
THE HIGH-AFFINITY COMPLEX BETWEEN IGE AND ITS RECEPTOR FC EPSILON RI
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR SUBUNIT ALPHA, IG EPSILON CHAIN C REGION, ...
Authors:Davies, A.M, Holdom, M.D, Nettleship, J.E, Beavil, A.J, Owens, R.J, Sutton, B.J.
Deposit date:2011-02-01
Release date:2011-04-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Conformational Changes in Ige Contribute to its Uniquely Slow Dissociation Rate from Receptor Fceri
Nat.Struct.Mol.Biol., 18, 2011
3BC2
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BU of 3bc2 by Molmil
METALLO BETA-LACTAMASE II FROM BACILLUS CEREUS 569/H/9 AT PH 6.0, MONOCLINIC CRYSTAL FORM
Descriptor: METALLO BETA-LACTAMASE II, ZINC ION
Authors:Fabiane, S.M, Sutton, B.J.
Deposit date:1997-09-09
Release date:1999-04-20
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Null
To be Published
1ADQ
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BU of 1adq by Molmil
CRYSTAL STRUCTURE OF A HUMAN IGM RHEUMATOID FACTOR FAB IN COMPLEX WITH ITS AUTOANTIGEN IGG FC
Descriptor: IGG4 REA FC, IGM-LAMBDA RF-AN FAB (HEAVY CHAIN), IGM-LAMBDA RF-AN FAB (LIGHT CHAIN)
Authors:Corper, A.L, Taussig, M.J, Sutton, B.J.
Deposit date:1997-02-18
Release date:1998-09-16
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structure of human IgM rheumatoid factor Fab bound to its autoantigen IgG Fc reveals a novel topology of antibody-antigen interaction.
Nat.Struct.Biol., 4, 1997
2BFZ
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BU of 2bfz by Molmil
Bacillus cereus metallo-beta-lactamase (BcII) Arg (121) Cys mutant. Solved at pH4.5 using 20mM ZnSO4 in buffer. 1mM DTT was used as a reducing agent. Cys221 is oxidized.
Descriptor: AZIDE ION, BETA-LACTAMASE II, GLYCEROL, ...
Authors:Davies, A.M, Rasia, R.M, Vila, A.J, Sutton, B.J, Fabiane, S.M.
Deposit date:2004-12-16
Release date:2005-03-31
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Effect of Ph on the Active Site of an Arg121Cys Mutant of the Metallo-Beta-Lactamase from Bacillus Cereus: Implications for the Enzyme Mechanism
Biochemistry, 44, 2005
2BG2
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BU of 2bg2 by Molmil
Bacillus cereus metallo-beta-lactamase (BcII) Arg (121) Cys mutant. Solved at pH4.5 using 20mM ZnSO4 in the buffer. 1mM DTT and 1mM TCEP- HCl were used as reducing agents. Cys221 is reduced.
Descriptor: BETA-LACTAMASE II, CHLORIDE ION, GLYCEROL, ...
Authors:Davies, A.M, Rasia, R.M, Vila, A.J, Sutton, B.J, Fabiane, S.M.
Deposit date:2004-12-16
Release date:2005-03-31
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Effect of Ph on the Active Site of an Arg121Cys Mutant of the Metallo-Beta-Lactamase from Bacillus Cereus: Implications for the Enzyme Mechanism.
Biochemistry, 44, 2005
2BFL
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BU of 2bfl by Molmil
Bacillus cereus metallo-beta-lactamase (BcII) Arg (121) Cys mutant. Solved at pH5 using 20mM ZnSO4 in buffer. 1mM DTT was used as a reducing agent.
Descriptor: AZIDE ION, GLYCEROL, Metallo-beta-lactamase type 2, ...
Authors:Davies, A.M, Rasia, R.M, Vila, A.J, Sutton, B.J, Fabiane, S.M.
Deposit date:2004-12-08
Release date:2005-03-31
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Effect of Ph on the Active Site of an Arg121Cys Mutant of the Metallo-Beta-Lactamase from Bacillus Cereus: Implications for the Enzyme Mechanism
Biochemistry, 44, 2005
2BFK
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BU of 2bfk by Molmil
Bacillus cereus metallo-beta-lactamase (BcII) Arg (121) Cys mutant. Solved at pH7 using 20mM ZnSO4 in buffer. 1mM DTT was used as a reducing agent
Descriptor: AZIDE ION, BETA-LACTAMASE II, GLYCEROL, ...
Authors:Davies, A.M, Rasia, R.M, Vila, A.J, Sutton, B.J, Fabiane, S.M.
Deposit date:2004-12-07
Release date:2005-03-31
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Effect of Ph on the Active Site of an Arg121Cys Mutant of the Metallo-Beta-Lactamase from Bacillus Cereus: Implications for the Enzyme Mechanism
Biochemistry, 44, 2005
2BG6
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BU of 2bg6 by Molmil
Bacillus cereus metallo-beta-lactamase (BcII) Arg (121) Cys mutant. Solved at pH5 using 20 Micromolar ZnSO4 in the buffer. 1mM DTT was used as a reducing agent. Cys221 is oxidized.
Descriptor: AZIDE ION, BETA-LACTAMASE II, GLYCEROL, ...
Authors:Davies, A.M, Rasia, R.M, Vila, A.J, Sutton, B.J, Fabiane, S.M.
Deposit date:2004-12-17
Release date:2005-03-31
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Effect of Ph on the Active Site of an Arg121Cys Mutant of the Metallo-Beta-Lactamase from Bacillus Cereus: Implications for the Enzyme Mechanism
Biochemistry, 44, 2005
2BG7
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BU of 2bg7 by Molmil
Bacillus cereus metallo-beta-lactamase (BcII) Arg (121) Cys mutant. Solved at pH4.5 using 20 Micromolar ZnSO4 in the buffer. 1mM DTT was used as a reducing agent. Cys221 is oxidized.
Descriptor: BETA-LACTAMASE II, GLYCEROL, SULFATE ION, ...
Authors:Davies, A.M, Rasia, R.M, Vila, A.J, Sutton, B.J, Fabiane, S.M.
Deposit date:2004-12-17
Release date:2005-03-31
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Effect of Ph on the Active Site of an Arg121Cys Mutant of the Metallo-Beta-Lactamase from Bacillus Cereus: Implications for the Enzyme Mechanism
Biochemistry, 44, 2005
2BG8
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BU of 2bg8 by Molmil
Bacillus cereus metallo-beta-lactamase (BcII) Arg (121) Cys mutant. Solved at pH4.5 using 20 Micromolar ZnSO4 in the buffer. 1mM DTT and 1mM TCEP-HCl were used as reducing agents.
Descriptor: BETA-LACTAMASE II, GLYCEROL, SULFATE ION, ...
Authors:Davies, A.M, Rasia, R.M, Vila, A.J, Sutton, B.J, Fabiane, S.M.
Deposit date:2004-12-17
Release date:2005-03-31
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Effect of Ph on the Active Site of an Arg121Cys Mutant of the Metallo-Beta-Lactamase from Bacillus Cereus: Implications for the Enzyme Mechanism
Biochemistry, 44, 2005
2BGA
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BU of 2bga by Molmil
Bacillus cereus metallo-beta-lactamase (BcII) Arg (121) Cys mutant. Solved at pH7 using 20 Micromolar ZnSO4 in the buffer. 1mM DTT was used as a reducing agent. Cys221 is oxidized.
Descriptor: AZIDE ION, BETA-LACTAMASE II, GLYCEROL, ...
Authors:Davies, A.M, Rasia, R.M, Vila, A.J, Sutton, B.J, Fabiane, S.M.
Deposit date:2004-12-17
Release date:2005-03-31
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Effect of Ph on the Active Site of an Arg121Cys Mutant of the Metallo-Beta-Lactamase from Bacillus Cereus: Implications for the Enzyme Mechanism
Biochemistry, 44, 2005
2BC2
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BU of 2bc2 by Molmil
METALLO BETA-LACTAMASE II FROM BACILLUS CEREUS 569/H/9 AT PH 6.0, TRIGONAL CRYSTAL FORM
Descriptor: METALLO BETA-LACTAMASE II, SULFATE ION, ZINC ION
Authors:Fabiane, S.M, Sutton, B.J.
Deposit date:1997-09-09
Release date:1999-04-20
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Null
To be Published
6Y0L
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BU of 6y0l by Molmil
Crystal structure of human CD23 lectin domain N225D, K229E, S252N, T251N, R253G, S254G mutant
Descriptor: GLYCEROL, Low affinity immunoglobulin epsilon Fc receptor membrane-bound form, SULFATE ION
Authors:Ilkow, V.F, Davies, A.M, Sutton, B.J, McDonnell, J.M.
Deposit date:2020-02-09
Release date:2021-06-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Reviving lost binding sites: Exploring calcium-binding site transitions between human and murine CD23.
Febs Open Bio, 11, 2021
6Y0M
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BU of 6y0m by Molmil
Crystal structure of human CD23 lectin domain N225D, K229E, S252N, T251N mutant
Descriptor: Low affinity immunoglobulin epsilon Fc receptor membrane-bound form
Authors:Ilkow, V.F, Davies, A.M, Sutton, B.J, McDonnell, J.M.
Deposit date:2020-02-09
Release date:2021-06-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Reviving lost binding sites: Exploring calcium-binding site transitions between human and murine CD23.
Febs Open Bio, 11, 2021
2J8M
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BU of 2j8m by Molmil
Structure of P. aeruginosa acetyltransferase PA4866
Descriptor: ACETYLTRANSFERASE PA4866 FROM P. AERUGINOSA, AZIDE ION, GLYCEROL, ...
Authors:Davies, A.M, Tata, R, Beavil, R.L, Sutton, B.J, Brown, P.R.
Deposit date:2006-10-26
Release date:2007-02-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:L-Methionine Sulfoximine, But not Phosphinothricin, is a Substrate for an Acetyltransferase (Gene Pa4866) from Pseudomonas Aeruginosa: Structural and Functional Studies.
Biochemistry, 46, 2007
2J8R
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BU of 2j8r by Molmil
Structure of P. aeruginosa acetyltransferase PA4866 solved in complex with L-Methionine sulfoximine
Descriptor: (2S)-2-AMINO-4-(METHYLSULFONIMIDOYL)BUTANOIC ACID, ACETYLTRANSFERASE PA4866 FROM P. AERUGINOSA, AZIDE ION, ...
Authors:Davies, A.M, Tata, R, Beavil, R.L, Sutton, B.J, Brown, P.R.
Deposit date:2006-10-27
Release date:2007-02-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:L-Methionine Sulfoximine, But not Phosphinothricin, is a Substrate for an Acetyltransferase (Gene Pa4866) from Pseudomonas Aeruginosa: Structural and Functional Studies.
Biochemistry, 46, 2007
2J8N
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BU of 2j8n by Molmil
Structure of P. aeruginosa acetyltransferase PA4866 solved at room temperature
Descriptor: ACETYLTRANSFERASE PA4866 FROM P. AERUGINOSA
Authors:Davies, A.M, Tata, R, Beavil, R.L, Sutton, B.J, Brown, P.R.
Deposit date:2006-10-26
Release date:2007-02-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:l-Methionine sulfoximine, but not phosphinothricin, is a substrate for an acetyltransferase (gene PA4866) from Pseudomonas aeruginosa: structural and functional studies.
Biochemistry, 46, 2007
1XBH
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BU of 1xbh by Molmil
A BETA-HAIRPIN MIMIC FROM FCERI-ALPHA-CYCLO(L-262)
Descriptor: PROTEIN (CYCLO(L-262))
Authors:Mcdonnell, J.M, Fushman, D, Cahill, S.M, Sutton, B.J, Cowburn, D.
Deposit date:1999-02-17
Release date:1999-02-21
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution Structures of FceRI Alpha-Chain Mimics: A Beta-Hairpin Peptide and Its Retroenantiomer
J.Am.Chem.Soc., 119, 1997

 

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