Author results

1BIR
  • Download 1bir
  • View 1bir
Molmil generated image of 1bir
RIBONUCLEASE T1, PHE 100 TO ALA MUTANT COMPLEXED WITH 2' GMP
Descriptor:RIBONUCLEASE T1, CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE
Authors:Doumen, J., Gonciarz, M., Zegers, I., Loris, R., Wyns, L., Steyaert, J.
Deposit date:1996-01-04
Release date:1996-08-17
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A catalytic function for the structurally conserved residue Phe 100 of ribonuclease T1.
Protein Sci., 5, 1996
1LRA
  • Download 1lra
  • View 1lra
Molmil generated image of 1lra
CRYSTALLOGRAPHIC STUDY OF GLU 58 ALA RNASE T1(ASTERISK)2'-GUANOSINE MONOPHOSPHATE AT 1.9 ANGSTROMS RESOLUTION
Descriptor:RIBONUCLEASE T1, SODIUM ION, GUANOSINE-2'-MONOPHOSPHATE
Authors:Pletinckx, J., Steyaert, J., Choe, H.-W., Heinemann, U., Wyns, L.
Deposit date:1993-10-01
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystallographic study of Glu58Ala RNase T1 x 2'-guanosine monophosphate at 1.9-A resolution.
Biochemistry, 33, 1994
1YOE
  • Download 1yoe
  • View 1yoe
Molmil generated image of 1yoe
CRYSTAL STRUCTURE OF A THE E. COLI PYRIMIDINE NUCLEOSIDE HYDROLASE YBEK WITH BOUND RIBOSE
Descriptor:Hypothetical protein ybeK, RIBOSE, CALCIUM ION
Authors:Muzzolini, L., Versees, W., Steyaert, J., Degano, M.
Deposit date:2005-01-27
Release date:2006-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Crystal structure of the E. coli pyrimidine nucleoside hydrolase YbeK with bound ribose
To be Published
1BU4
  • Download 1bu4
  • View 1bu4
Molmil generated image of 1bu4
RIBONUCLEASE 1 COMPLEX WITH 2'GMP
Descriptor:RIBONUCLEASE T1, CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE
Authors:Loris, R., Devos, S., Langhorst, U., Decanniere, K., Bouckaert, J., Maes, D., Transue, T.R., Steyaert, J.
Deposit date:1998-09-11
Release date:1999-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Conserved water molecules in a large family of microbial ribonucleases.
Proteins, 36, 1999
1BVI
  • Download 1bvi
  • View 1bvi
Molmil generated image of 1bvi
RIBONUCLEASE T1 (WILDTYPE) COMPLEXED WITH 2'GMP
Descriptor:PROTEIN (RIBONUCLEASE T1), GUANOSINE-2'-MONOPHOSPHATE, CALCIUM ION
Authors:Langhorst, U., Loris, R., Denisov, V.P., Doumen, J., Roose, P., Maes, D., Halle, B., Steyaert, J.
Deposit date:1998-09-15
Release date:1998-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Dissection of the structural and functional role of a conserved hydration site in RNase T1.
Protein Sci., 8, 1999
1HOZ
  • Download 1hoz
  • View 1hoz
Molmil generated image of 1hoz
CRYSTAL STRUCTURE OF AN INOSINE-ADENOSINE-GUANOSINE-PREFERRING NUCLEOSIDE HYDROLASE FROM TRYPANOSOMA VIVAX
Descriptor:INOSINE-ADENOSINE-GUANOSINE-PREFERRING NUCLEOSIDE HYDROLASE, CALCIUM ION, GLYCEROL
Authors:Versees, W., Decanniere, K., Pelle, R., Depoorter, J., Parkin, D.W., Steyaert, J.
Deposit date:2000-12-12
Release date:2001-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure and function of a novel purine specific nucleoside hydrolase from Trypanosoma vivax.
J.Mol.Biol., 307, 2001
1HP0
  • Download 1hp0
  • View 1hp0
Molmil generated image of 1hp0
CRYSTAL STRUCTURE OF AN INOSINE-ADENOSINE-GUANOSINE-PREFERRING NUCLEOSIDE HYDROLASE FROM TRYPANOSOMA VIVAX IN COMPLEX WITH THE SUBSTRATE ANALOGUE 3-DEAZA-ADENOSINE
Descriptor:INOSINE-ADENOSINE-GUANOSINE-PREFERRING NUCLEOSIDE HYDROLASE, CALCIUM ION, 3-DEAZA-ADENOSINE
Authors:Versees, W., Decanniere, K., Pelle, R., Depoorter, J., Parkin, D.W., Steyaert, J.
Deposit date:2000-12-12
Release date:2001-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and function of a novel purine specific nucleoside hydrolase from Trypanosoma vivax.
J.Mol.Biol., 307, 2001
1HYF
  • Download 1hyf
  • View 1hyf
Molmil generated image of 1hyf
RIBONUCLEASE T1 V16A MUTANT IN COMPLEX WITH SR2+
Descriptor:GUANYL-SPECIFIC RIBONUCLEASE T1, STRONTIUM ION, GUANOSINE-2'-MONOPHOSPHATE
Authors:De Swarte, J., De Vos, S., Langhorst, U., Steyaert, J., Loris, R.
Deposit date:2001-01-19
Release date:2001-02-14
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The contribution of metal ions to the conformational stability of ribonuclease T1: crystal versus solution.
Eur.J.Biochem., 268, 2001
1HZ1
  • Download 1hz1
  • View 1hz1
Molmil generated image of 1hz1
RIBONUCLEASE T1 V16A MUTANT IN COMPLEX WITH MG2+
Descriptor:RIBONUCLEASE T1, MAGNESIUM ION, GUANOSINE-2'-MONOPHOSPHATE
Authors:De Swarte, J., De Vos, S., Langhorst, U., Steyaert, J., Loris, R.
Deposit date:2001-01-23
Release date:2001-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The contribution of metal ions to the conformational stability of ribonuclease T1: crystal versus solution.
Eur.J.Biochem., 268, 2001
1I0V
  • Download 1i0v
  • View 1i0v
Molmil generated image of 1i0v
RIBONUCLEASE T1 IN COMPLEX WITH 2'GMP (FORM I CRYSTAL)
Descriptor:GUANYL-SPECIFIC RIBONUCLEASE T1, CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE
Authors:De Swarte, J., De Vos, S., Langhorst, U., Steyaert, J., Loris, R.
Deposit date:2001-01-30
Release date:2001-02-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.234 Å)
Cite:The contribution of metal ions to the conformational stability of ribonuclease T1: crystal versus solution.
Eur.J.Biochem., 268, 2001
1I0X
  • Download 1i0x
  • View 1i0x
Molmil generated image of 1i0x
RIBONUCLEASE T1 IN COMPLEX WITH 2'GMP (FORM II CRYSTAL)
Descriptor:GUANYL-SPECIFIC RIBONUCLEASE T1, GUANOSINE-2'-MONOPHOSPHATE, CALCIUM ION
Authors:De Swarte, J., De Vos, S., Langhorst, U., Steyaert, J., Loris, R.
Deposit date:2001-01-30
Release date:2001-02-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The contribution of metal ions to the conformational stability of ribonuclease T1: crystal versus solution.
Eur.J.Biochem., 268, 2001
1I2E
  • Download 1i2e
  • View 1i2e
Molmil generated image of 1i2e
RIBONUCLEASE T1 V16A MUTANT, FORM I
Descriptor:GUANYL-SPECIFIC RIBONUCLEASE T1, CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE
Authors:De Vos, S., Backmann, J., Steyaert, J., Loris, R.
Deposit date:2001-02-09
Release date:2001-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Hydrophobic core manipulations in ribonuclease T1
Biochemistry, 40, 2001
1I2F
  • Download 1i2f
  • View 1i2f
Molmil generated image of 1i2f
RIBONUCLEASE T1 V16A MUTANT, FORM II
Descriptor:GUANYL-SPECIFIC RIBONUCLEASE T1, CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE
Authors:De Vos, S., Backmann, J., Steyaert, J., Loris, R.
Deposit date:2001-02-09
Release date:2001-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Hydrophobic core manipulations in ribonuclease T1
Biochemistry, 40, 2001
1I2G
  • Download 1i2g
  • View 1i2g
Molmil generated image of 1i2g
RIBONUCLEASE T1 V16T MUTANT
Descriptor:GUANYL-SPECIFIC RIBONUCLEASE T1, CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE
Authors:De Vos, S., Backmann, J., Steyaert, J., Loris, R.
Deposit date:2001-02-09
Release date:2001-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Hydrophobic core manipulations in ribonuclease T1
Biochemistry, 40, 2001
1I3F
  • Download 1i3f
  • View 1i3f
Molmil generated image of 1i3f
RIBONUCLEASE T1 V89S MUTANT
Descriptor:GUANYL-SPECIFIC RIBONUCLEASE T1, CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE
Authors:De Vos, S., Backmann, J., Steyaert, J., Loris, R.
Deposit date:2001-02-15
Release date:2001-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Hydrophobic core manipulations in ribonuclease T1
Biochemistry, 40, 2001
1I3I
  • Download 1i3i
  • View 1i3i
Molmil generated image of 1i3i
RIBONUCLEASE T1 V78T MUTANT
Descriptor:GUANYL-SPECIFIC RIBONUCLEASE T1, CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE
Authors:De Vos, S., Backmann, J., Steyaert, J., Loris, R.
Deposit date:2001-02-15
Release date:2001-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Hydrophobic core manipulations in ribonuclease T1
Biochemistry, 40, 2001
2BIR
  • Download 2bir
  • View 2bir
Molmil generated image of 2bir
ADDITIVITY OF SUBSTRATE BINDING IN RIBONUCLEASE T1 (Y42A MUTANT)
Descriptor:RIBONUCLEASE T1, CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE
Authors:Doumen, J., Steyaert, J., Loverix, S.
Deposit date:1996-12-03
Release date:1997-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Additivity of protein-guanine interactions in ribonuclease T1.
J.Biol.Chem., 272, 1997
2BU4
  • Download 2bu4
  • View 2bu4
Molmil generated image of 2bu4
RIBONUCLEASE T1 COMPLEX WITH 2'GMP
Descriptor:PROTEIN (RIBONUCLEASE T1), CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE
Authors:Loris, R., Devos, S., Langhorst, U., Decanniere, K., Bouckaert, J., Maes, D., Transue, T.R., Steyaert, J.
Deposit date:1998-09-14
Release date:1998-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Conserved water molecules in a large family of microbial ribonucleases.
Proteins, 36, 1999
2FF1
  • Download 2ff1
  • View 2ff1
Molmil generated image of 2ff1
CRYSTAL STRUCTURE OF TRYPANOSOMA VIVAX NUCLEOSIDE HYDROLASE SOAKED WITH IMMUCILLINH
Descriptor:IAG-nucleoside hydrolase, CALCIUM ION, 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL
Authors:Versees, W., Barlow, J., Steyaert, J.
Deposit date:2005-12-18
Release date:2006-05-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Transition-state Complex of the Purine-specific Nucleoside Hydrolase of T.vivax: Enzyme Conformational Changes and Implications for Catalysis.
J.Mol.Biol., 359, 2006
2FF2
  • Download 2ff2
  • View 2ff2
Molmil generated image of 2ff2
CRYSTAL STRUCTURE OF TRYPANOSOMA VIVAX NUCLEOSIDE HYDROLASE CO-CRYSTALLIZED WITH IMMUCILLINH
Descriptor:IAG-nucleoside hydrolase, CALCIUM ION, NICKEL (II) ION, ...
Authors:Versees, W., Barlow, J., Steyaert, J.
Deposit date:2005-12-18
Release date:2006-05-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Transition-state Complex of the Purine-specific Nucleoside Hydrolase of T.vivax: Enzyme Conformational Changes and Implications for Catalysis.
J.Mol.Biol., 359, 2006
2HOH
  • Download 2hoh
  • View 2hoh
Molmil generated image of 2hoh
RIBONUCLEASE T1 (N9A MUTANT) COMPLEXED WITH 2'GMP
Descriptor:PROTEIN (RIBONUCLEASE T1), GUANOSINE-2'-MONOPHOSPHATE, SODIUM ION, ...
Authors:Langhorst, U., Loris, R., Denisov, V.P., Doumen, J., Roose, P., Maes, D., Halle, B., Steyaert, J.
Deposit date:1998-09-14
Release date:1998-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Dissection of the structural and functional role of a conserved hydration site in RNase T1.
Protein Sci., 8, 1999
2NXW
  • Download 2nxw
  • View 2nxw
Molmil generated image of 2nxw
CRYSTAL STRUCTURE OF PHENYLPYRUVATE DECARBOXYLASE OF AZOSPIRILLUM BRASILENSE
Descriptor:PHENYL-3-PYRUVATE DECARBOXYLASE, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Versees, W., Spaepen, S., Vanderleyden, J., Steyaert, J.
Deposit date:2006-11-20
Release date:2007-05-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The crystal structure of phenylpyruvate decarboxylase from Azospirillum brasilense at 1.5 A resolution. Implications for its catalytic and regulatory mechanism.
Febs J., 274, 2007
2Q5J
  • Download 2q5j
  • View 2q5j
Molmil generated image of 2q5j
X-RAY STRUCTURE OF PHENYLPYRUVATE DECARBOXYLASE IN COMPLEX WITH 3-DEAZA-THDP
Descriptor:Phenylpyruvate decarboxylase, MAGNESIUM ION, 2-{4-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-3-METHYLTHIOPHEN-2-YL}ETHYL TRIHYDROGEN DIPHOSPHATE
Authors:Versees, W., Spaepen, S., Wood, M.D., Leeper, F.J., Vanderleyden, J., Steyaert, J.
Deposit date:2007-06-01
Release date:2007-10-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Molecular mechanism of allosteric substrate activation in a thiamine diphosphate-dependent decarboxylase.
J.Biol.Chem., 282, 2007
2Q5L
  • Download 2q5l
  • View 2q5l
Molmil generated image of 2q5l
X-RAY STRUCTURE OF PHENYLPYRUVATE DECARBOXYLASE IN COMPLEX WITH 2-(1-HYDROXYETHYL)-3-DEAZA-THDP
Descriptor:PHENYLPYRUVATE DECARBOXYLASE, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Versees, W., Spaepen, S., Wood, M.D., Leeper, F.J., Vanderleyden, J., Steyaert, J.
Deposit date:2007-06-01
Release date:2007-10-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Molecular mechanism of allosteric substrate activation in a thiamine diphosphate-dependent decarboxylase.
J.Biol.Chem., 282, 2007
2Q5O
  • Download 2q5o
  • View 2q5o
Molmil generated image of 2q5o
X-RAY STRUCTURE OF PHENYLPYRUVATE DECARBOXYLASE IN COMPLEX WITH 3-DEAZA-THDP AND PHENYLPYRUVATE
Descriptor:Phenylpyruvate decarboxylase, MAGNESIUM ION, 2-{4-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-3-METHYLTHIOPHEN-2-YL}ETHYL TRIHYDROGEN DIPHOSPHATE, ...
Authors:Versees, W., Spaepen, S., Wood, M.D., Leeper, F.J., Vanderleyden, J., Steyaert, J.
Deposit date:2007-06-01
Release date:2007-10-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Molecular mechanism of allosteric substrate activation in a thiamine diphosphate-dependent decarboxylase.
J.Biol.Chem., 282, 2007