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4AT1
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STRUCTURAL CONSEQUENCES OF EFFECTOR BINDING TO THE T STATE OF ASPARTATE CARBAMOYLTRANSFERASE. CRYSTAL STRUCTURES OF THE UNLIGATED AND ATP-, AND CTP-COMPLEXED ENZYMES AT 2.6-ANGSTROMS RESOLUTION
分子名称:ASPARTATE CARBAMOYLTRANSFERASE (T STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
著者Stevens, R.C., Gouaux, J.E., Lipscomb, W.N.
登録日1990-04-26
公開日1990-10-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural consequences of effector binding to the T state of aspartate carbamoyltransferase: crystal structures of the unligated and ATP- and CTP-complexed enzymes at 2.6-A resolution.
Biochemistry, 29, 1990
5AT1
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STRUCTURAL CONSEQUENCES OF EFFECTOR BINDING TO THE T STATE OF ASPARTATE CARBAMOYLTRANSFERASE. CRYSTAL STRUCTURES OF THE UNLIGATED AND ATP-, AND CTP-COMPLEXED ENZYMES AT 2.6-ANGSTROMS RESOLUTION
分子名称:ASPARTATE CARBAMOYLTRANSFERASE (T STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
著者Stevens, R.C., Gouaux, J.E., Lipscomb, W.N.
登録日1990-04-26
公開日1990-10-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural consequences of effector binding to the T state of aspartate carbamoyltransferase: crystal structures of the unligated and ATP- and CTP-complexed enzymes at 2.6-A resolution.
Biochemistry, 29, 1990
6AT1
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STRUCTURAL CONSEQUENCES OF EFFECTOR BINDING TO THE T STATE OF ASPARTATE CARBAMOYLTRANSFERASE. CRYSTAL STRUCTURES OF THE UNLIGATED AND ATP-, AND CTP-COMPLEXED ENZYMES AT 2.6-ANGSTROMS RESOLUTION
分子名称:ASPARTATE CARBAMOYLTRANSFERASE (T STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
著者Stevens, R.C., Gouaux, J.E., Lipscomb, W.N.
登録日1990-04-26
公開日1990-10-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural consequences of effector binding to the T state of aspartate carbamoyltransferase: crystal structures of the unligated and ATP- and CTP-complexed enzymes at 2.6-A resolution.
Biochemistry, 29, 1990
2AT2
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MOLECULAR STRUCTURE OF BACILLUS SUBTILIS ASPARTATE TRANSCARBAMOYLASE AT 3.0 ANGSTROMS RESOLUTION
分子名称:ASPARTATE CARBAMOYLTRANSFERASE
著者Stevens, R.C., Reinisch, K.M., Lipscomb, W.N.
登録日1992-07-20
公開日1994-01-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Molecular structure of Bacillus subtilis aspartate transcarbamoylase at 3.0 A resolution.
Proc.Natl.Acad.Sci.USA, 88, 1991
1ACM
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ARGININE 54 IN THE ACTIVE SITE OF ESCHERICHIA COLI ASPARTATE TRANSCARBAMOYLASE IS CRITICAL FOR CATALYSIS: A SITE-SPECIFIC MUTAGENESIS, NMR AND X-RAY CRYSTALLOGRAPHY STUDY
分子名称:ASPARTATE CARBAMOYLTRANSFERASE, CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
著者Stevens, R.C., Kantrowitz, E.R., Lipscomb, W.N.
登録日1992-07-08
公開日1992-07-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Arginine 54 in the active site of Escherichia coli aspartate transcarbamoylase is critical for catalysis: a site-specific mutagenesis, NMR, and X-ray crystallographic study.
Protein Sci., 1, 1992
1FL3
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CRYSTAL STRUCTURE OF THE BLUE FLUORESCENT ANTIBODY (19G2) IN COMPLEX WITH STILBENE HAPTEN AT 277K
分子名称:BLUE FLUORESCENT ANTIBODY (19G2)-HEAVY CHAIN, BLUE FLUORESCENT ANTIBODY (19G2)-LIGHT CHAIN, 4-(4-STYRYL-PHENYLCARBAMOYL)-BUTYRIC ACID
著者Stevens, R.C., Beuscher IV, A.E.
登録日2000-08-11
公開日2000-11-01
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Blue-fluorescent antibodies.
Science, 290, 2000
1HTZ
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CRYSTAL STRUCTURE OF TEM52 BETA-LACTAMASE
分子名称:BETA-LACTAMASE MUTANT TEM52
著者Stevens, R.C., Orencia, M.C.
登録日2001-01-03
公開日2001-03-21
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Predicting the emergence of antibiotic resistance by directed evolution and structural analysis.
Nat.Struct.Biol., 8, 2001
1PAH
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HUMAN PHENYLALANINE HYDROXYLASE DIMER, RESIDUES 117-424
分子名称:PHENYLALANINE HYDROXYLASE, FE (III) ION
著者Stevens, R.C., Erlandsen, H.
登録日1997-10-25
公開日1999-01-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the catalytic domain of human phenylalanine hydroxylase reveals the structural basis for phenylketonuria.
Nat.Struct.Biol., 4, 1997
2NYY
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CRYSTAL STRUCTURE OF BOTULINUM NEUROTOXIN TYPE A COMPLEXED WITH MONOCLONAL ANTIBODY CR1
分子名称:Botulinum neurotoxin type A, CR1 monoclonal antibody, ZINC ION, ...
著者Stevens, R.C., Arndt, J.W.
登録日2006-11-21
公開日2006-12-26
最終更新日2016-02-17
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Molecular evolution of antibody cross-reactivity for two subtypes of type A botulinum neurotoxin.
Nat.Biotechnol., 25, 2007
2NZ9
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CRYSTAL STRUCTURE OF BOTULINUM NEUROTOXIN TYPE A COMPLEXED WITH MONOCLONAL ANTIBODY AR2
分子名称:Botulinum neurotoxin type A, AR2 monoclonal antibody, ZINC ION, ...
著者Stevens, R.C., Arndt, J.W.
登録日2006-11-22
公開日2006-12-26
最終更新日2016-02-17
実験手法X-RAY DIFFRACTION (3.79 Å)
主引用文献Molecular evolution of antibody cross-reactivity for two subtypes of type A botulinum neurotoxin.
Nat.Biotechnol., 25, 2007
2PAH
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TETRAMERIC HUMAN PHENYLALANINE HYDROXYLASE
分子名称:PROTEIN (PHENYLALANINE HYDROXYLASE), FE (III) ION
著者Stevens, R.C., Fusetti, F., Erlandsen, H.
登録日1998-05-26
公開日1999-10-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of tetrameric human phenylalanine hydroxylase and its implications for phenylketonuria.
J.Biol.Chem., 273, 1998
3BTA
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CRYSTAL STRUCTURE OF BOTULINUM NEUROTOXIN SEROTYPE A
分子名称:PROTEIN (BOTULINUM NEUROTOXIN TYPE A), ZINC ION
著者Stevens, R.C., Lacy, D.B.
登録日1998-08-12
公開日1999-10-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of botulinum neurotoxin type A and implications for toxicity.
Nat.Struct.Biol., 5, 1998
3CZO
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CRYSTAL STRUCTURE OF DOUBLE MUTANT PHENYLALANINE AMMONIA-LYASE FROM ANABAENA VARIABILIS
分子名称:Histidine ammonia-lyase
著者Stevens, R.C., Wang, L.
登録日2008-04-29
公開日2008-05-20
最終更新日2012-12-26
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and biochemical characterization of the therapeutic Anabaena variabilis phenylalanine ammonia lyase.
J.Mol.Biol., 380, 2008
1AJ7
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IMMUNOGLOBULIN 48G7 GERMLINE FAB ANTIBODY COMPLEXED WITH HAPTEN 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID. AFFINITY MATURATION OF AN ESTEROLYTIC ANTIBODY
分子名称:IMMUNOGLOBULIN 48G7 FAB (LIGHT CHAIN), IMMUNOGLOBULIN 48G7 FAB (HEAVY CHAIN), 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID
著者Wedemayer, G.J., Wang, L.H., Patten, P.A., Schultz, P.G., Stevens, R.C.
登録日1997-05-15
公開日1997-11-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural insights into the evolution of an antibody combining site.
Science, 276, 1997
2RCS
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IMMUNOGLOBULIN 48G7 GERMLINE FAB-AFFINITY MATURATION OF AN ESTEROLYTIC ANTIBODY
分子名称:IMMUNOGLOBULIN 48G7 GERMLINE FAB
著者Wedemayer, G.J., Wang, L.H., Patten, P.A., Schultz, P.G., Stevens, R.C.
登録日1997-05-14
公開日1997-11-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural insights into the evolution of an antibody combining site.
Science, 276, 1997
7AT1
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CRYSTAL STRUCTURES OF ASPARTATE CARBAMOYLTRANSFERASE LIGATED WITH PHOSPHONOACETAMIDE, MALONATE, AND CTP OR ATP AT 2.8-ANGSTROMS RESOLUTION AND NEUTRAL P*H
分子名称:ASPARTATE CARBAMOYLTRANSFERASE (R STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
著者Gouaux, J.E., Stevens, R.C., Lipscomb, W.N.
登録日1989-09-22
公開日1990-10-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structures of aspartate carbamoyltransferase ligated with phosphonoacetamide, malonate, and CTP or ATP at 2.8-A resolution and neutral pH.
Biochemistry, 29, 1990
8AT1
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CRYSTAL STRUCTURES OF ASPARTATE CARBAMOYLTRANSFERASE LIGATED WITH PHOSPHONOACETAMIDE, MALONATE, AND CTP OR ATP AT 2.8-ANGSTROMS RESOLUTION AND NEUTRAL P*H
分子名称:ASPARTATE CARBAMOYLTRANSFERASE (R STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
著者Gouaux, J.E., Stevens, R.C., Lipscomb, W.N.
登録日1989-09-22
公開日1990-10-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structures of aspartate carbamoyltransferase ligated with phosphonoacetamide, malonate, and CTP or ATP at 2.8-A resolution and neutral pH.
Biochemistry, 29, 1990
1E74
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NMR SOLUTION STRUCTURE OF ALPHA-CONOTOXIN IM1 POINT MUTATION VARIANT R11E
分子名称:ALPHA-CONOTOXIN IM1(R11E)
著者Rogers, J.P., Luginbuhl, P., Pemberton, K., Harty, P., Wemmer, D.E., Stevens, R.C.
登録日2000-08-24
公開日2000-12-27
最終更新日2017-06-14
実験手法SOLUTION NMR
主引用文献Structure-Activity Relationships in a Peptidic Alpha7 Nicotinic Acetylcholine Receptor Antagonist
J.Mol.Biol., 304, 2000
1E75
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NMR SOLUTION STRUCTURE OF ALPHA-CONOTOXIN IM1 POINT MUTATION VARIANT R7L
分子名称:ALPHA-CONOTOXIN IM1(R7L)
著者Rogers, J.P., Luginbuhl, P., Pemberton, K., Harty, P., Wemmer, D.E., Stevens, R.C.
登録日2000-08-24
公開日2000-12-27
最終更新日2017-06-14
実験手法SOLUTION NMR
主引用文献Structure-Activity Relationships in a Peptidic Alpha7 Nicotinic Acetylcholine Receptor Antagonist
J.Mol.Biol., 304, 2000
1E76
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NMR SOLUTION STRUCTURE OF ALPHA-CONOTOXIN IM1 POINT MUTATION VARIANT D5N
分子名称:ALPHA-CONOTOXIN IM1(D5N)
著者Rogers, J.P., Luginbuhl, P., Pemberton, K., Harty, P., Wemmer, D.E., Stevens, R.C.
登録日2000-08-24
公開日2000-12-27
最終更新日2017-06-14
実験手法SOLUTION NMR
主引用文献Structure-Activity Relationships in a Peptidic Alpha7 Nicotinic Acetylcholine Receptor Antagonist
J.Mol.Biol., 304, 2000
1HKL
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FREE AND LIGANDED FORM OF AN ESTEROLYTIC CATALYTIC ANTIBODY
分子名称:48G7 FAB
著者Wedemayer, G.J., Wang, L.H., Patten, P.A., Schultz, P.G., Stevens, R.C.
登録日1996-12-20
公開日1997-03-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Crystal structures of the free and liganded form of an esterolytic catalytic antibody.
J.Mol.Biol., 268, 1997
2RH1
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HIGH RESOLUTION CRYSTAL STRUCTURE OF HUMAN B2-ADRENERGIC G PROTEIN-COUPLED RECEPTOR.
分子名称:beta-2-adrenergic receptor/T4-lysozyme chimera, MALTOSE, SULFATE ION, ...
著者Cherezov, V., Rosenbaum, D.M., Hanson, M.A., Rasmussen, S.G.F., Thian, F.S., Kobilka, T.S., Choi, H.J., Kuhn, P., Weis, W.I., Kobilka, B.K., Stevens, R.C., Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR)
登録日2007-10-05
公開日2007-10-30
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor.
Science, 318, 2007
1A4J
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DIELS ALDER CATALYTIC ANTIBODY GERMLINE PRECURSOR
分子名称:IMMUNOGLOBULIN, DIELS ALDER CATALYTIC ANTIBODY (LIGHT CHAIN), DIELS ALDER CATALYTIC ANTIBODY (HEAVY CHAIN)
著者Spiller, B.W., Romesburg, F.E., Schultz, P.G., Stevens, R.C.
登録日1998-01-30
公開日1998-05-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Immunological origins of binding and catalysis in a Diels-Alderase antibody.
Science, 279, 1998
1A4K
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DIELS ALDER CATALYTIC ANTIBODY WITH TRANSITION STATE ANALOGUE
分子名称:ANTIBODY FAB, CADMIUM ION, [4-(4-ACETYLAMINO-PHENYL)-3,5-DIOXO-4-AZA-TRICYCLO[5.2.2.0 2,6]UNDEC-1-YLCARBAMOYLOXY]-ACETIC ACID
著者Spiller, B.W., Romesburg, F.E., Schultz, P.G., Stevens, R.C.
登録日1998-01-30
公開日1998-05-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Immunological origins of binding and catalysis in a Diels-Alderase antibody.
Science, 279, 1998
1AXS
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MATURE OXY-COPE CATALYTIC ANTIBODY WITH HAPTEN
分子名称:OXY-COPE CATALYTIC ANTIBODY, CADMIUM ION, (1S,2S,5S)2-(4-GLUTARIDYLBENZYL)-5-PHENYL-1-CYCLOHEXANOL
著者Mundorff, E.C., Ulrich, H.D., Stevens, R.C.
登録日1997-10-20
公開日1998-02-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The interplay between binding energy and catalysis in the evolution of a catalytic antibody.
Nature, 389, 1997