9B3Q
 
 | | The structure of the human cardiac F-actin mutant A331P | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... | | Authors: | Doran, M.H, Sousa, D, Rynkiewicz, M.J, Lehman, W, Cammarato, A. | | Deposit date: | 2024-03-20 | | Release date: | 2024-05-29 | | Last modified: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structure of human cardiac actin
To Be Published
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9B3R
 | | The structure of human cardiac F-actin | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... | | Authors: | Doran, M.H, Sousa, D, Rynkiewicz, M.J, Lehman, W, Cammarato, A. | | Deposit date: | 2024-03-20 | | Release date: | 2024-05-29 | | Last modified: | 2025-06-11 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | The hypertrophic cardiomyopathy-associated A331P actin variant enhances basal contractile activity and elicits resting muscle dysfunction.
Iscience, 28, 2025
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6CBE
 | | Atomic structure of a rationally engineered gene delivery vector, AAV2.5 | | Descriptor: | Capsid protein VP1 | | Authors: | Burg, M, Rosebrough, C, Drouin, L, Bennett, A, Mietzsch, M, Chipman, P, McKenna, R, Sousa, D, Potter, M, Byrne, B, Kozyreva, O.G, Samulski, R.J, Agbandje-McKenna, M. | | Deposit date: | 2018-02-02 | | Release date: | 2018-05-30 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (2.78 Å) | | Cite: | Atomic structure of a rationally engineered gene delivery vector, AAV2.5.
J. Struct. Biol., 203, 2018
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5U9G
 | | 3.2 A cryo-EM ArfA-RF2 ribosome rescue complex (Structure I) | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Demo, G, Svidritskiy, E, Madireddy, R, Diaz-Avalos, R, Grant, T, Grigorieff, N, Sousa, D, Korostelev, A.A. | | Deposit date: | 2016-12-16 | | Release date: | 2017-03-22 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Mechanism of ribosome rescue by ArfA and RF2.
Elife, 6, 2017
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5U9F
 | | 3.2 A cryo-EM ArfA-RF2 ribosome rescue complex (Structure II) | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Demo, G, Svidritskiy, E, Madireddy, R, Diaz-Avalos, R, Grant, T, Grigorieff, N, Sousa, D, Korostelev, A.A. | | Deposit date: | 2016-12-16 | | Release date: | 2017-03-22 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Mechanism of ribosome rescue by ArfA and RF2.
Elife, 6, 2017
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5URF
 | | The structure of human bocavirus 1 | | Descriptor: | viral protein 3 | | Authors: | Mietzsch, M, Kailasan, S, Garrison, J, Ilyas, M, Chipman, P, Kandola, K, Jansen, M, Spear, J, Sousa, D, McKenna, R, Soderlund-Venermo, M, Baker, T, Agbandje-McKenna, M. | | Deposit date: | 2017-02-10 | | Release date: | 2017-03-29 | | Last modified: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural Insights into Human Bocaparvoviruses.
J. Virol., 91, 2017
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6NXE
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7U95
 | | SAAV pH 6.0 capsid structure | | Descriptor: | Capsid protein | | Authors: | Mietzsch, M, McKenna, R. | | Deposit date: | 2022-03-10 | | Release date: | 2022-04-13 | | Last modified: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (2.73 Å) | | Cite: | Characterization of the Serpentine Adeno-Associated Virus (SAAV) Capsid Structure: Receptor Interactions and Antigenicity.
J.Virol., 96, 2022
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7U97
 | | SAAV pH 4.0 capsid structure | | Descriptor: | Capsid protein | | Authors: | Mietzsch, M, McKenna, R. | | Deposit date: | 2022-03-10 | | Release date: | 2022-04-13 | | Last modified: | 2025-05-21 | | Method: | ELECTRON MICROSCOPY (2.66 Å) | | Cite: | Characterization of the Serpentine Adeno-Associated Virus (SAAV) Capsid Structure: Receptor Interactions and Antigenicity.
J.Virol., 96, 2022
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7U96
 | | SAAV pH 5.5 capsid structure | | Descriptor: | Capsid protein | | Authors: | Mietzsch, M, McKenna, R. | | Deposit date: | 2022-03-10 | | Release date: | 2022-04-13 | | Last modified: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (2.14 Å) | | Cite: | Characterization of the Serpentine Adeno-Associated Virus (SAAV) Capsid Structure: Receptor Interactions and Antigenicity.
J.Virol., 96, 2022
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7U94
 | | SAAV pH 7.4 capsid structure | | Descriptor: | Capsid protein | | Authors: | Mietzsch, M, McKenna, R. | | Deposit date: | 2022-03-10 | | Release date: | 2022-04-13 | | Last modified: | 2025-05-21 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | Characterization of the Serpentine Adeno-Associated Virus (SAAV) Capsid Structure: Receptor Interactions and Antigenicity.
J.Virol., 96, 2022
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6O9R
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6BX0
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6BX1
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6BWX
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6V1Z
 | | genome-containing AAVrh.39 particles | | Descriptor: | Capsid protein VP1, DNA (5'-D(*CP*A)-3') | | Authors: | Mietzsch, M, Agbandje-McKenna, M. | | Deposit date: | 2019-11-21 | | Release date: | 2019-12-11 | | Last modified: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (3.58 Å) | | Cite: | Comparative Analysis of the Capsid Structures of AAVrh.10, AAVrh.39, and AAV8.
J.Virol., 94, 2020
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6V12
 | | Empty AAV8 particles | | Descriptor: | Capsid protein | | Authors: | Mietzsch, M, Agbandje-McKenna, M. | | Deposit date: | 2019-11-19 | | Release date: | 2019-12-11 | | Last modified: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (3.08 Å) | | Cite: | Comparative Analysis of the Capsid Structures of AAVrh.10, AAVrh.39, and AAV8.
J.Virol., 94, 2020
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6V10
 | | genome-containing AAV8 particles | | Descriptor: | Capsid protein, DNA (5'-D(*CP*A)-3') | | Authors: | Mietzsch, M, Agbandje-McKenna, M. | | Deposit date: | 2019-11-19 | | Release date: | 2019-12-11 | | Last modified: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (3.77 Å) | | Cite: | Comparative Analysis of the Capsid Structures of AAVrh.10, AAVrh.39, and AAV8.
J.Virol., 94, 2020
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6V1G
 | | Genome-containing AAVrh.10 | | Descriptor: | Capsid protein VP1, DNA (5'-D(*CP*A)-3') | | Authors: | Mietzsch, M, Agbandje-McKenna, M. | | Deposit date: | 2019-11-20 | | Release date: | 2019-12-11 | | Last modified: | 2025-05-21 | | Method: | ELECTRON MICROSCOPY (2.98 Å) | | Cite: | Comparative Analysis of the Capsid Structures of AAVrh.10, AAVrh.39, and AAV8.
J.Virol., 94, 2020
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6V1T
 | | Empty AAVrh.39 particle | | Descriptor: | Capsid protein VP1 | | Authors: | Mietzsch, M, Agbandje-McKenna, M. | | Deposit date: | 2019-11-21 | | Release date: | 2019-12-11 | | Last modified: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (3.39 Å) | | Cite: | Comparative Analysis of the Capsid Structures of AAVrh.10, AAVrh.39, and AAV8.
J.Virol., 94, 2020
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5US9
 | | Human bocavirus 4 | | Descriptor: | Capsid protein VP2 | | Authors: | Mietzsch, M, Agbandje-McKenna, M. | | Deposit date: | 2017-02-13 | | Release date: | 2017-03-29 | | Last modified: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural Insights into Human Bocaparvoviruses.
J. Virol., 91, 2017
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5US7
 | | Human bocavirus 3 | | Descriptor: | VP2 | | Authors: | Mietzsch, M, Agbandje-McKenna, M. | | Deposit date: | 2017-02-13 | | Release date: | 2017-03-29 | | Last modified: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural Insights into Human Bocaparvoviruses.
J. Virol., 91, 2017
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7L0X
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7L0Y
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7NA6
 | | Cryo-EM structure of AAV True Type | | Descriptor: | Capsid protein VP1 | | Authors: | Bennett, A.D, McKenna, R. | | Deposit date: | 2021-06-19 | | Release date: | 2021-09-29 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | Comparative structural, biophysical, and receptor binding study of true type and wild type AAV2.
J.Struct.Biol., 213, 2021
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