Author results

3BD9
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HUMAN 3-O-SULFOTRANSFERASE ISOFORM 5 WITH BOUND PAP
Descriptor:Heparan sulfate glucosamine 3-O-sulfotransferase 5, ADENOSINE-3'-5'-DIPHOSPHATE
Authors:Xu, D., Moon, A.F., Song, D., Liu, J., Pedersen, L.C.
Deposit date:2007-11-14
Release date:2008-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Engineering sulfotransferases to modify heparan sulfate.
Nat.Chem.Biol., 4, 2008
4IM8
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LOW RESOLUTION CRYSTAL STRUCTURE OF MOUSE RAGE
Descriptor:Advanced glycation end-products receptor
Authors:Xu, D., Young, J.H., Krahn, J.M., Song, D., Corbett, K.D., Chazin, W.J., Pedersen, L.C., Esko, J.D.
Deposit date:2013-01-02
Release date:2013-08-14
Last modified:2014-02-26
Method:X-RAY DIFFRACTION (3.503 Å)
Cite:Stable RAGE-Heparan Sulfate Complexes Are Essential for Signal Transduction.
Acs Chem.Biol., 8, 2013
2A9H
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NMR STRUCTURAL STUDIES OF A POTASSIUM CHANNEL / CHARYBDOTOXIN COMPLEX
Descriptor:Voltage-gated potassium channel, charybdotoxin
Authors:Yu, L., Sun, C., Song, D., Shen, J., Xu, N., Gunasekera, A., Hajduk, P.J., Olejniczak, E.T.
Deposit date:2005-07-11
Release date:2006-01-10
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Nuclear magnetic resonance structural studies of a potassium channel-charybdotoxin complex.
Biochemistry, 44, 2005
2JOD
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PAC1-RSHORT N-TERMINAL EC DOMAIN PACAP(6-38) COMPLEX
Descriptor:Pituitary adenylate cyclase-activating polypeptide type I receptor, Pituitary adenylate cyclase-activating polypeptide
Authors:Olejniczak, E.T., Sun, C., Song, D., Davis-Taber, R.A., Barrett, L.W., Scott, V.E., Richardson, P.L., Pereda-lopez, A., Uchic, M.E., Solomon, L.R., Lake, M.R., Walter, K.A., Hajduk, P.J.
Deposit date:2007-03-07
Release date:2007-05-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure and mutational analysis of pituitary adenylate cyclase-activating polypeptide binding to the extracellular domain of PAC1-RS.
Proc.Natl.Acad.Sci.Usa, 104, 2007
4OQ5
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CRYSTAL STRUCTURE OF HUMAN MCL-1 BOUND TO INHIBITOR 4-(4-METHYLNAPHTHALEN-1-YL)-2-{[(4-PHENOXYPHENYL)SULFONYL]AMINO}BENZOIC ACID
Descriptor:Induced myeloid leukemia cell differentiation protein Mcl-1, 4-(4-methylnaphthalen-1-yl)-2-{[(4-phenoxyphenyl)sulfonyl]amino}benzoic acid
Authors:Petros, A.M., Swann, S.L., Song, D., Swinger, K., Park, C., Zhang, H., Wendt, M.D., Kunzer, A.R., Souers, A.J., Sun, C.
Deposit date:2014-02-07
Release date:2014-03-12
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Fragment-based discovery of potent inhibitors of the anti-apoptotic MCL-1 protein.
Bioorg.Med.Chem.Lett., 24, 2014
4OQ6
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CRYSTAL STRUCTURE OF HUMAN MCL-1 BOUND TO INHIBITOR 4-HYDROXY-4'-PROPYLBIPHENYL-3-CARBOXYLIC ACID
Descriptor:Induced myeloid leukemia cell differentiation protein Mcl-1, 4-hydroxy-4'-propylbiphenyl-3-carboxylic acid
Authors:Petros, A.M., Swann, S.L., Song, D., Swinger, K., Park, C., Zhang, H., Wendt, M.D., Kunzer, A.R., Souers, A.J., Sun, C.
Deposit date:2014-02-07
Release date:2014-03-12
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Fragment-based discovery of potent inhibitors of the anti-apoptotic MCL-1 protein.
Bioorg.Med.Chem.Lett., 24, 2014
3NEW
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P38-ALPHA COMPLEXED WITH COMPOUND 10
Descriptor:Mitogen-activated protein kinase 14, 4-(trifluoromethyl)-3-[3-(trifluoromethyl)phenyl]-1,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one
Authors:Goedken, E.R., Comess, K.M., Sun, C., Argiriadi, M., Jia, Y., Quinn, C.M., Banach, D.L., Marcotte, D., Borhani, D.
Deposit date:2010-06-09
Release date:2010-12-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Discovery and Characterization of Non-ATP Site Inhibitors of the Mitogen Activated Protein (MAP) Kinases.
Acs Chem.Biol., 6, 2011
3O17
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CRYSTAL STRUCTURE OF JNK1-ALPHA1 ISOFORM
Descriptor:Mitogen-activated protein kinase 8, C-Jun-amino-terminal kinase-interacting protein 1, JIP1, ...
Authors:Abad-Zapatero, C.
Deposit date:2010-07-20
Release date:2011-01-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structure of JNK1-alpha1 isoform
TO BE PUBLISHED
3O2M
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CRYSTAL STRUCTURE OF JNK1-ALPHA1 ISOFORM COMPLEX WITH A BIARYL TETRAZOL (A-82118)
Descriptor:Mitogen-activated protein kinase 8, C-Jun-amino-terminal kinase-interacting protein 1, JIP1, ...
Authors:Abad-Zapatero, C.
Deposit date:2010-07-22
Release date:2011-01-12
Last modified:2011-09-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Discovery and characterization of non-ATP site inhibitors of the mitogen activated protein (MAP) kinases.
Acs Chem.Biol., 6, 2011
6MBJ
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SETD3, A HISTIDINE METHYLTRANSFERASE, IN COMPLEX WITH AN ACTIN PEPTIDE AND SAH, P21 CRYSTAL FORM
Descriptor:Actin Peptide, Histone-lysine N-methyltransferase setd3, 1,2-ETHANEDIOL, ...
Authors:Horton, J.R., Dai, S., Cheng, X.
Deposit date:2018-08-30
Release date:2018-12-19
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:SETD3 is an actin histidine methyltransferase that prevents primary dystocia
Nature, 565, 2018
6MBK
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SETD3, A HISTIDINE METHYLTRANSFERASE, IN COMPLEX WITH AN ACTIN PEPTIDE AND SAH, FIRST P212121 CRYSTAL FORM
Descriptor:Actin peptide, Histone-lysine N-methyltransferase setd3, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Horton, J.R., Dai, S., Cheng, X.
Deposit date:2018-08-30
Release date:2018-12-19
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:SETD3 is an actin histidine methyltransferase that prevents primary dystocia
Nature, 565, 2018
6MBL
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SETD3, A HISTIDINE METHYLTRANSFERASE, IN COMPLEX WITH AN ACTIN PEPTIDE AND SAH, SECOND P212121 CRYSTAL FORM
Descriptor:Actin Peptide, Histone-lysine N-methyltransferase setd3, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Horton, J.R., Dai, S., Cheng, X.
Deposit date:2018-08-30
Release date:2018-12-19
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (2.197 Å)
Cite:SETD3 is an actin histidine methyltransferase that prevents primary dystocia
Nature, 565, 2018