Author results

2CMW
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STRUCTURE OF HUMAN CASEIN KINASE 1 GAMMA-1 IN COMPLEX WITH 2-(2- HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYLPURINE
分子名称:CASEIN KINASE I ISOFORM GAMMA-1, 2-(2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYLPURINE, PHOSPHATE ION, ...
著者Bunkoczi, G., Rellos, P., Das, S., Savitsky, P., Niesen, F., Sobott, F., Fedorov, O., Pike, A.C.W., von Delft, F., Sundstrom, M., Arrowsmith, C., Edwards, A., Weigelt, J., Knapp, S.
登録日2006-05-15
公開日2006-06-15
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure of Human Casein Kinase 1 Gamma-1 in Complex with 2-(2-Hydroxyethylamino)-6-(3-Chloroanilino)-9-Isopropylpurine (Casp Target)
To be Published
2J1L
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CRYSTAL STRUCTURE OF HUMAN RHO-RELATED GTP-BINDING PROTEIN RHOD
分子名称:RHO-RELATED GTP-BINDING PROTEIN RHOD, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Pike, A.C.W., Johansson, C., Gileadi, C., Niesen, F.H., Sobott, F., Schoch, G., Elkins, J., Smee, C., Gorrec, F., Watt, S., Bray, J., Turnbull, A.P., von Delft, F., Arrowsmith, C., Edwards, A., Weigelt, J., Sundstrom, M., Doyle, D.
登録日2006-08-14
公開日2006-09-18
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of Human Rho-Related GTP-Binding Protein Rhod
To be Published
2UZP
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CRYSTAL STRUCTURE OF THE C2 DOMAIN OF HUMAN PROTEIN KINASE C GAMMA.
分子名称:PROTEIN KINASE C GAMMA TYPE, PYRIDOXAL-5'-PHOSPHATE, COBALT (II) ION, ...
著者Pike, A.C.W., Amos, A., Johansson, C., Sobott, F., Savitsky, P., Berridge, G., Fedorov, O., Umeano, C., Gorrec, F., Bunkoczi, G., Debreczeni, J., von Delft, F., Arrowsmith, C.H., Edwards, A., Weigelt, J., Sundstrom, M., Knapp, S.
登録日2007-04-30
公開日2007-05-29
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of C2 Domain of Protein Kinase C Gamma
To be Published
2BUJ
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CRYSTAL STRUCTURE OF THE HUMAN SERINE-THREONINE KINASE 16 IN COMPLEX WITH STAUROSPORINE
分子名称:SERINE/THREONINE-PROTEIN KINASE 16, CHLORIDE ION, STAUROSPORINE
著者Debreczeni, J.E., Eswaran, J., Bullock, A., Filippakopoulos, P., Kavanagh, K., Amos, A., Fedorov, O., Sobott, F., Ball, L.J., von Delft, F., Arrowsmith, C., Sundstrom, M., Edwards, A., Knapp, S.
登録日2005-06-13
公開日2005-07-05
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of the Human Serine-Threonine Kinase 16 in Complex with Staurosporine
To be Published
2C47
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STRUCTURE OF CASEIN KINASE 1 GAMMA 2
分子名称:CASEIN KINASE 1 GAMMA 2 ISOFORM, (2R,3R,4S,5R)-2-(4-AMINO-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL, MAGNESIUM ION
著者Bunkoczi, G., Rellos, P., Das, S., Ugochukwu, E., Fedorov, O., Sobott, F., Eswaran, J., Amos, A., Ball, L., von Delft, F., Bullock, A., Debreczeni, J., Turnbull, A., Sundstrom, M., Weigelt, J., Arrowsmith, C., Edwards, A., Knapp, S.
登録日2005-10-16
公開日2005-11-07
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Structure of Casein Kinase 1 Gamma 2
To be Published
2CLS
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THE CRYSTAL STRUCTURE OF THE HUMAN RND1 GTPASE IN THE ACTIVE GTP BOUND STATE
分子名称:RHO-RELATED GTP-BINDING PROTEIN RHO6, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
著者Pike, A.C.W., Yang, X., Colebrook, S., Gileadi, O., Sobott, F., Bray, J., Wen Hwa, L., Marsden, B., Zhao, Y., Schoch, G., Elkins, J., Debreczeni, J.E., Turnbull, A.P., von Delft, F., Arrowsmith, C., Edwards, A., Weigelt, J., Sundstrom, M., Doyle, D.
登録日2006-04-28
公開日2006-05-04
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献The Crystal Structure of the Human Rnd1 Gtpase in the Active GTP Bound State
To be Published
2EXE
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CRYSTAL STRUCTURE OF THE PHOSPHORYLATED CLK3
分子名称:Dual specificity protein kinase CLK3
著者Papagrigoriou, E., Rellos, P., Das, S., Bullock, A., Ball, L.J., Turnbull, A., Savitsky, P., Fedorov, O., Johansson, C., Ugochukwu, E., Sobott, F., von Delft, F., Edwards, A., Sundstrom, M., Weigelt, J., Arrowsmith, C., Knapp, S., Structural Genomics Consortium (SGC)
登録日2005-11-08
公開日2005-11-15
最終更新日2012-05-02
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal structure of the phosphorylated CLK3
TO BE PUBLISHED
2JAM
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CRYSTAL STRUCTURE OF HUMAN CALMODULIN-DEPENDENT PROTEIN KINASE I G
分子名称:CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1G, POLYPEPTIDE, 1,2-ETHANEDIOL, ...
著者Debreczeni, J.E., Bullock, A., Keates, T., Niesen, F.H., Salah, E., Shrestha, L., Smee, C., Sobott, F., Pike, A.C.W., Bunkoczi, G., von Delft, F., Turnbull, A., Weigelt, J., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Knapp, S.
登録日2006-11-29
公開日2007-03-13
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of Human Calmodulin-Dependent Protein Kinase I G
To be Published
2BQ0
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14-3-3 PROTEIN BETA (HUMAN)
分子名称:14-3-3 BETA/ALPHA
著者Yang, X., Elkins, J.M., Fedorov, O., Longman, E.J., Sobott, L., Ball, L.J., Sundstrom, M., Arrowsmith, C., Edwards, A., Doyle, D.A.
登録日2005-04-26
公開日2005-05-06
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis for Protein-Protein Interactions in the 14-3-3 Protein Family.
Proc.Natl.Acad.Sci.USA, 103, 2006
2IWI
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CRYSTAL STRUCTURE OF THE HUMAN PIM2 IN COMPLEX WITH A RUTHENIUM ORGANOMETALLIC LIGAND RU1
分子名称:SERINE/THREONINE-PROTEIN KINASE PIM-2, RUTHENIUM-PYRIDOCARBAZOLE-1
著者Russo, S., Debreczeni, J.E., Amos, A., Bullock, A.N., Fedorov, O., Niesen, F., Sobott, F., Turnbull, A., Pike, A.C.W., Ugochukwu, E., Papagrigoriou, E., Bunkoczi, G., Gorrec, F., Edwards, A., Arrowsmith, C., Weigelt, J., Sundstrom, M., von Delft, F., Knapp, S.
登録日2006-06-30
公開日2006-08-02
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the PIM2 kinase in complex with an organoruthenium inhibitor.
PLoS ONE, 4, 2009
2XDV
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF FLJ14393
分子名称:MYC-INDUCED NUCLEAR ANTIGEN, N-OXALYLGLYCINE, NICKEL (II) ION, ...
著者Krojer, T., Muniz, J.R.C., Ng, S.S., Pilka, E., Guo, K., Pike, A.C.W., Filippakopoulos, P., Knapp, S., Kavanagh, K.L., Gileadi, O., Bunkoczi, G., Yue, W.W., Niesen, F., Sobott, F., Fedorov, O., Savitsky, P., Kochan, G., Daniel, M., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Oppermann, U.
登録日2010-05-07
公開日2010-05-26
最終更新日2018-02-21
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Ribosomal oxygenases are structurally conserved from prokaryotes to humans.
Nature, 510, 2014
2ES0
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STRUCTURE OF THE REGULATOR OF G-PROTEIN SIGNALING DOMAIN OF RGS6
分子名称:regulator of G-protein signalling 6
著者Schoch, G.A., Phillips, C., Turnbull, A., Niesen, F., Johansson, C., Elkins, J.M., Longman, E., Gilealdi, C., Sobott, F., Ball, L., Sundstrom, M., Edwards, A., Arrowsmith, C., von Delft, F., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2005-10-25
公開日2005-11-29
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2J7T
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CRYSTAL STRUCTURE OF HUMAN SERINE THREONINE KINASE-10 BOUND TO SU11274
分子名称:SERINE/THREONINE-PROTEIN KINASE 10, CALCIUM ION, ACETATE ION, ...
著者Pike, A.C.W., Rellos, P., Fedorov, O., Das, S., Debreczeni, J., Sobott, F., Watt, S., Savitsky, P., Eswaran, J., Turnbull, A.P., Papagrigoriou, E., Ugochukwa, E., Gorrec, F., Umeano, C.C., von Delft, F., Arrowsmith, C.H., Edwards, A., Weigelt, J., Sundstrom, M., Knapp, S.
登録日2006-10-17
公開日2006-11-07
最終更新日2018-06-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Activation Segment Dimerization: A Mechanism for Kinase Autophosphorylation of Non-Consensus Sites.
Embo J., 27, 2008
2OC3
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN PROTEIN TYROSINE PHOSPHATASE NON-RECEPTOR TYPE 18
分子名称:Tyrosine-protein phosphatase non-receptor type 18
著者Ugochukwu, E., Barr, A., Alfano, I., Gorrec, F., Umeano, C., Savitsky, P., Sobott, F., Eswaran, J., Papagrigoriou, E., Debreczeni, J.E., Turnbull, A., Bunkoczi, G., Sundstrom, M., Arrowsmith, C.H., Weigelt, J., Edwards, A., von Delft, F., Knapp, S., Structural Genomics Consortium (SGC)
登録日2006-12-20
公開日2007-01-30
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Large-scale structural analysis of the classical human protein tyrosine phosphatome.
Cell(Cambridge,Mass.), 136, 2009
1Z57
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CRYSTAL STRUCTURE OF HUMAN CLK1 IN COMPLEX WITH 10Z-HYMENIALDISINE
分子名称:Dual specificity protein kinase CLK1, DEBROMOHYMENIALDISINE
著者Debreczeni, J., Das, S., Knapp, S., Bullock, A., Guo, K., Amos, A., Fedorov, O., Edwards, A., Sundstrom, M., von Delft, F., Niesen, F.H., Ball, L., Sobott, F., Arrowsmith, C., Structural Genomics Consortium (SGC)
登録日2005-03-17
公開日2005-04-12
最終更新日2012-08-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Kinase domain insertions define distinct roles of CLK kinases in SR protein phosphorylation.
Structure, 17, 2009
2AHS
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN TYROSINE RECEPTOR PHOSPHATASE BETA
分子名称:Receptor-type tyrosine-protein phosphatase beta, CHLORIDE ION, SODIUM ION, ...
著者Ugochukwu, E., Eswaran, J., Barr, A., Gileadi, O., Sobott, F., Burgess, N., Ball, L., Bray, J., von Delft, F., Debreczeni, J., Bunkoczi, G., Turnbull, A., Das, S., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Knapp, S., Structural Genomics Consortium (SGC)
登録日2005-07-28
公開日2005-08-09
最終更新日2012-03-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Large-scale structural analysis of the classical human protein tyrosine phosphatome.
Cell(Cambridge,Mass.), 136, 2009
2CLQ
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STRUCTURE OF MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5
分子名称:MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5, STAUROSPORINE
著者Bunkoczi, G., Salah, E., Fedorov, O., Pike, A., Gileadi, O., von Delft, F., Arrowsmith, C., Edwards, A., Sundstrom, M., Weigelt, J., Knapp, S.
登録日2006-04-28
公開日2006-05-09
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Functional Characterization of the Human Protein Kinase Ask1.
Structure, 15, 2007
2EU9
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CRYSTAL STRUCTURE OF CLK3
分子名称:Dual specificity protein kinase CLK3, 1,2-ETHANEDIOL
著者Papagrigoriou, E., Rellos, P., Das, S., Ugochukwu, E., Turnbull, A., von Delft, F., Bunkoczi, G., Sobott, F., Bullock, A., Fedorov, O., Gileadi, C., Savitsky, P., Edwards, A., Aerrowsmith, C., Weigelt, J., Sundstrom, M., Knapp, S.
登録日2005-10-28
公開日2005-11-08
最終更新日2012-08-29
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Kinase domain insertions define distinct roles of CLK kinases in SR protein phosphorylation.
Structure, 17, 2009
2G3Y
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CRYSTAL STRUCTURE OF THE HUMAN SMALL GTPASE GEM
分子名称:GTP-binding protein GEM, GUANOSINE-5'-DIPHOSPHATE
著者Ugochukwu, E., Soundararajan, M., Elkins, J., Gileadi, C., Schoch, G., Sobott, F., Fedorov, O., Bray, J., Pantic, N., Berridge, G., Burgess, N., Lee, W.H., Turnbull, A., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., von Delft, F., Doyle, D., Structural Genomics Consortium (SGC)
登録日2006-02-21
公開日2006-04-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the human small GTPase GEM
To be Published
2JII
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STRUCTURE OF VACCINIA RELATED KINASE 3
分子名称:SERINE/THREONINE-PROTEIN KINASE VRK3 MOLECULE: VACCINIA RELATED KINASE 3, 1,2-ETHANEDIOL
著者Bunkoczi, G., Eswaran, J., Pike, A.C.W., Uppenberg, J., Ugochukwu, E., von Delft, F., Cooper, C., Salah, E., Savitsky, P., Burgess-Brown, N., Keates, T., Fedorov, O., Sobott, F., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Weigelt, J., Knapp, S.
登録日2007-06-28
公開日2007-07-10
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the pseudokinase VRK3 reveals a degraded catalytic site, a highly conserved kinase fold, and a putative regulatory binding site.
Structure, 17, 2009
5NOC
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SOLUTION NMR STRUCTURE OF THE C-TERMINAL DOMAIN OF PARB (SPO0J)
分子名称:Stage 0 sporulation protein J
著者Higman, V.A., Fisher, G.L.M., Dillingham, M.S., Crump, M.P.
登録日2017-04-11
公開日2017-12-13
最終更新日2019-05-08
実験手法SOLUTION NMR
主引用文献The structural basis for dynamic DNA binding and bridging interactions which condense the bacterial centromere.
Elife, 6, 2017
2BMJ
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GTPASE LIKE DOMAIN OF CENTAURIN GAMMA 1 (HUMAN)
分子名称:CENTAURIN GAMMA 1
著者Yang, X., Elkins, J.M., Soundararajan, M., Arrowsmith, C., Edwards, A., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2005-03-14
公開日2005-04-12
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Centaurin Gamma-1 Gtpase-Like Domain Functions as an Ntpase.
Biochem.J., 401, 2007
2BR9
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14-3-3 PROTEIN EPSILON (HUMAN) COMPLEXED TO PEPTIDE
分子名称:14-3-3 PROTEIN EPSILON, CONSENSUS PEPTIDE FOR 14-3-3 PROTEINS
著者Yang, X., Elkins, J.M., Soundararajan, M., Fedorov, O., Sundstrom, M., Edwards, A., Arrowsmith, C., Doyle, D.A.
登録日2005-05-03
公開日2005-05-12
最終更新日2013-12-04
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural Basis for Protein-Protein Interactions in the 14-3-3 Protein Family.
Proc.Natl.Acad.Sci.USA, 103, 2006
2BTP
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14-3-3 PROTEIN THETA (HUMAN) COMPLEXED TO PEPTIDE
分子名称:14-3-3 PROTEIN TAU, CONSENSUS PEPTIDE FOR 14-3-3 PROTEINS
著者Elkins, J.M., Johansson, A.C.E., Smee, C., Yang, X., Sundstrom, M., Edwards, A., Arrowsmith, C., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2005-06-05
公開日2005-06-28
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for Protein-Protein Interactions in the 14-3-3 Protein Family.
Proc.Natl.Acad.Sci.USA, 103, 2006
2C23
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14-3-3 PROTEIN BETA (HUMAN) IN COMPLEX WITH EXOENZYME S PEPTIDE
分子名称:14-3-3 BETA/ALPHA, EXOENZYME S PEPTIDE
著者Elkins, J.M., Schoch, G.A., Yang, X., Sundstrom, M., Arrowsmith, C., Edwards, A., Doyle, D.A.
登録日2005-09-26
公開日2005-09-29
最終更新日2013-12-04
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural Basis for Protein-Protein Interactions in the 14-3-3 Protein Family.
Proc.Natl.Acad.Sci.USA, 103, 2006
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