Author results

3EAP
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CRYSTAL STRUCTURE OF THE RHOGAP DOMAIN OF ARHGAP11A
分子名称:Rho GTPase-activating protein 11A, UNKNOWN ATOM OR ION
著者Shen, Y., Shen, L., Tong, Y., Tempel, W., MacKenzie, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium, Structural Genomics Consortium (SGC)
登録日2008-08-26
公開日2008-09-02
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the RhoGAP domain of ARHGAP11A
To be Published
3GF9
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CRYSTAL STRUCTURE OF HUMAN INTERSECTIN 2 RHOGEF DOMAIN
分子名称:Intersectin 2, UNKNOWN ATOM OR ION
著者Shen, Y., Tong, Y., Tempel, W., Li, Y., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2009-02-26
公開日2009-03-10
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of human Intersectin 2 RhoGEF domain
To be Published
3JZY
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CRYSTAL STRUCTURE OF HUMAN INTERSECTIN 2 C2 DOMAIN
分子名称:Intersectin 2, UNKNOWN ATOM OR ION
著者Shen, Y., Tempel, W., Tong, Y., Li, Y., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2009-09-24
公開日2009-10-06
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Crystal structure of human Intersectin 2 C2 domain
To be Published
1LVC
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CRYSTAL STRUCTURE OF THE ADENYLYL CYCLASE DOMAIN OF ANTHRAX EDEMA FACTOR (EF) IN COMPLEX WITH CALMODULIN AND 2' DEOXY, 3' ANTHRANILOYL ATP
分子名称:calmodulin-sensitive adenylate cyclase, calmodulin, YTTERBIUM (III) ION, ...
著者Shen, Y., Lee, Y.-S., Soelaiman, S., Bergson, P., Lu, D., Chen, A., Beckingham, K., Grabarek, Z., Mrksich, M., Tang, W.-J.
登録日2002-05-28
公開日2002-12-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Physiological calcium concentrations regulate calmodulin binding and catalysis of adenylyl cyclase exotoxins
Embo J., 21, 2002
1PK0
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CRYSTAL STRUCTURE OF THE EF3-CAM COMPLEXED WITH PMEAPP
分子名称:Calmodulin-sensitive adenylate cyclase, Calmodulin, YTTERBIUM (III) ION, ...
著者Shen, Y., Tang, W.J.
登録日2003-06-04
公開日2004-02-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Selective inhibition of anthrax edema factor by adefovir, a drug for chronic hepatitis B virus infection.
Proc.Natl.Acad.Sci.USA, 101, 2004
1S26
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STRUCTURE OF ANTHRAX EDEMA FACTOR-CALMODULIN-ALPHA,BETA-METHYLENEADENOSINE 5'-TRIPHOSPHATE COMPLEX REVEALS AN ALTERNATIVE MODE OF ATP BINDING TO THE CATALYTIC SITE
分子名称:Calmodulin-sensitive adenylate cyclase, Calmodulin, YTTERBIUM (III) ION, ...
著者Shen, Y., Zhukovskaya, N.L., Bohm, A., Tang, W.-J.
登録日2004-01-08
公開日2004-04-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of anthrax edema factor-calmodulin-adenosine-5'-(alpha,beta-methylene)-triphosphate complex reveals an alternative mode of ATP binding to the catalytic site
Biochem.Biophys.Res.Commun., 317, 2004
3DZ8
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CRYSTAL STRUCTURE OF HUMAN RAB3B GTPASE BOUND WITH GDP
分子名称:Ras-related protein Rab-3B, GUANOSINE-5'-DIPHOSPHATE, UNKNOWN ATOM OR ION
著者Shen, Y., Tong, Y., Sukumar, D., Tempel, W., Loppnau, P., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Wilkstrom, M., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2008-07-29
公開日2008-08-12
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of human Rab3B GTPase bound with GDP
To be Published
3KH0
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CRYSTAL STRUCTURE OF THE RAS-ASSOCIATION (RA) DOMAIN OF RALGDS
分子名称:Ral guanine nucleotide dissociation stimulator, UNKNOWN ATOM OR ION
著者Shen, Y., Tempel, W., Wang, H., Tong, Y., Guan, X., Crombet, L., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2009-10-29
公開日2009-11-17
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the Ras-association (RA) domain of RALGDS
to be published
3LXX
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CRYSTAL STRUCTURE OF HUMAN GTPASE IMAP FAMILY MEMBER 4
分子名称:GTPase IMAP family member 4, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Shen, Y., Nedyalkova, L., Tong, Y., Tempel, W., Mackenzie, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Andrews, D.W., Park, H., Structural Genomics Consortium (SGC)
登録日2010-02-25
公開日2010-03-09
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of human GTPase IMAP family member 4
to be published
3MPX
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CRYSTAL STRUCTURE OF THE DH AND PH-1 DOMAINS OF HUMAN FGD5
分子名称:FYVE, RhoGEF and PH domain-containing protein 5, UNKNOWN ATOM OR ION
著者Shen, Y., Nedyalkova, L., Tong, Y., Tempel, W., Crombet, L., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2010-04-27
公開日2010-06-23
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the DH and PH-1 domains of human FGD5
TO BE PUBLISHED
3NEY
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CRYSTAL STRUCTURE OF THE KINASE DOMAIN OF MPP1/P55
分子名称:55 kDa erythrocyte membrane protein, SULFATE ION, UNKNOWN ATOM OR ION
著者Shen, Y., Tong, Y., Zhong, N., Guan, X., Tempel, W., MacKenzie, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2010-06-09
公開日2010-08-04
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Crystal structure of the kinase domain of MPP1/p55
To be Published
6BBK
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N-TERMINALLY TRUNCATED GROUP I PILA FROM PSEUDOMONAS AERUGINOSA STRAIN 1244
分子名称:Fimbrial protein
著者Shen, Y., Guarne, A., Nguyen, Y., Burrows, L.L.
登録日2017-10-18
公開日2018-11-21
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献N-terminally truncated group I PilA from Pseudomonas aeruginosa strain 1244
To Be Published
1NR3
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SOLUTION STRUCTURE OF THE PROTEIN MTH0916: THE NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET TT212
分子名称:DNA-binding protein tfx
著者Shen, Y., Liu, G., Bhaskaran, R., Yee, A., Arrowsmith, C., Szyperski, T., Northeast Structural Genomics Consortium (NESG)
登録日2003-01-23
公開日2003-06-10
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献SOLUTION STRUCTURE OF THE PROTEIN MTH0916: THE NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET TT212
To be Published
1T17
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SOLUTION STRUCTURE OF THE 18 KDA PROTEIN CC1736 FROM CAULOBACTER CRESCENTUS: THE NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET CCR19
分子名称:conserved hypothetical protein
著者Shen, Y., Atreya, H.S., Acton, T., Xiao, R., Montelione, G.T., Szyperski, T., Northeast Structural Genomics Consortium (NESG)
登録日2004-04-15
公開日2005-01-04
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献NMR structure of the 18 kDa protein CC1736 from Caulobacter crescentus identifies a member of the START domain superfamily and suggests residues mediating substrate specificity.
Proteins, 58, 2005
1W93
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE DOMAIN OF ACETYL-COENZYME A CARBOXYLASE FROM SACCHAROMYCES CEREVISIAE
分子名称:ACETYL-COENZYME A CARBOXYLASE
著者Shen, Y., Volrath, S.L., Weatherly, S.C., Elich, T.D., Tong, L.
登録日2004-10-05
公開日2005-01-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A Mechanism for the Potent Inhibition of Eukaryotic Acetyl-Coenzyme a Carboxylase by Soraphen A, a Macrocyclic Polyketide Natural Product
Mol.Cell, 16, 2004
1W96
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE DOMAIN OF ACETYL-COENZYME A CARBOXYLASE FROM SACCHAROMYCES CEREVISIAE IN COMPLEX WITH SORAPHEN A
分子名称:ACETYL-COENZYME A CARBOXYLASE, SORAPHEN A
著者Shen, Y., Volrath, S.L., Weatherly, S.C., Elich, T.D., Tong, L.
登録日2004-10-06
公開日2005-01-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A Mechanism for the Potent Inhibition of Eukaryotic Acetyl-Coenzyme a Carboxylase by Soraphen A, a Macrocyclic Polyketide Natural Product
Mol.Cell, 16, 2004
1XFU
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CRYSTAL STRUCTURE OF ANTHRAX EDEMA FACTOR (EF) TRUNCATION MUTANT, EF-DELTA 64 IN COMPLEX WITH CALMODULIN
分子名称:Calmodulin-sensitive adenylate cyclase, Calmodulin 2, MAGNESIUM ION, ...
著者Shen, Y., Zhukovskaya, N.L., Guo, Q., Florian, J., Tang, W.J.
登録日2004-09-15
公開日2005-05-03
最終更新日2017-12-20
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor.
EMBO J., 24, 2005
1XFW
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CRYSTAL STRUCTURE OF ANTHRAX EDEMA FACTOR (EF) IN COMPLEX WITH CALMODULIN AND 3'5' CYCLIC AMP (CAMP)
分子名称:Calmodulin-sensitive adenylate cyclase, Calmodulin 2, MAGNESIUM ION, ...
著者Shen, Y., Zhukovskaya, N.L., Guo, Q., Florian, J., Tang, W.J.
登録日2004-09-15
公開日2005-05-03
最終更新日2017-12-20
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor.
EMBO J., 24, 2005
1XFX
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CRYSTAL STRUCTURE OF ANTHRAX EDEMA FACTOR (EF) IN COMPLEX WITH CALMODULIN IN THE PRESENCE OF 10 MILLIMOLAR EXOGENOUSLY ADDED CALCIUM CHLORIDE
分子名称:Calmodulin-sensitive adenylate cyclase, Calmodulin 2, MAGNESIUM ION, ...
著者Shen, Y., Zhukovskaya, N.L., Guo, Q., Florian, J., Tang, W.J.
登録日2004-09-15
公開日2005-05-03
最終更新日2017-12-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor.
EMBO J., 24, 2005
1XFY
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CRYSTAL STRUCTURE OF ANTHRAX EDEMA FACTOR (EF) IN COMPLEX WITH CALMODULIN
分子名称:Calmodulin-sensitive adenylate cyclase, Calmodulin 2, MAGNESIUM ION, ...
著者Shen, Y., Zhukovskaya, N.L., Guo, Q., Florian, J., Tang, W.J.
登録日2004-09-15
公開日2005-05-03
最終更新日2017-12-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor.
EMBO J., 24, 2005
1XFZ
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CRYSTAL STRUCTURE OF ANTHRAX EDEMA FACTOR (EF) IN COMPLEX WITH CALMODULIN IN THE PRESENCE OF 1 MILLIMOLAR EXOGENOUSLY ADDED CALCIUM CHLORIDE
分子名称:Calmodulin-sensitive adenylate cyclase, Calmodulin 2, MAGNESIUM ION, ...
著者Shen, Y., Zhukovskaya, N.L., Guo, Q., Florian, J., Tang, W.J.
登録日2004-09-15
公開日2005-05-03
最終更新日2017-12-20
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor.
EMBO J., 24, 2005
1XN7
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SOLUTION STRUCTURE OF E.COLI PROTEIN YHGG: THE NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ET95
分子名称:Hypothetical protein yhgG
著者Shen, Y., Acton, T., Atreya, H.S., Ma, L., Liu, G., Xiao, R., Montelione, G.T., Szyperski, T., Northeast Structural Genomics Consortium (NESG)
登録日2004-10-04
公開日2004-12-14
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution Structure of E.Coli Protein yhgG: The Northeast Structural Genomics Consortium Target ET95
To be Published
1Y0V
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CRYSTAL STRUCTURE OF ANTHRAX EDEMA FACTOR (EF) IN COMPLEX WITH CALMODULIN AND PYROPHOSPHATE
分子名称:Calmodulin-sensitive adenylate cyclase, Calmodulin, MAGNESIUM ION, ...
著者Shen, Y., Zhukovskaya, N.L., Guo, Q., Florian, J., Tang, W.-J.
登録日2004-11-16
公開日2005-05-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor
Embo J., 24, 2005
2G47
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CRYSTAL STRUCTURE OF HUMAN INSULIN-DEGRADING ENZYME IN COMPLEX WITH AMYLOID-BETA (1-40)
分子名称:Insulin-degrading enzyme, amyloid protein beta A4, 1,4-DIETHYLENE DIOXIDE
著者Shen, Y., Tang, W.-J.
登録日2006-02-21
公開日2006-10-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism.
Nature, 443, 2006
2G48
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CRYSTAL STRUCTURE OF HUMAN INSULIN-DEGRADING ENZYME IN COMPLEX WITH AMYLIN
分子名称:Insulin-degrading enzyme, Islet amyloid polypeptide, 1,4-DIETHYLENE DIOXIDE
著者Shen, Y., Tang, W.-J.
登録日2006-02-21
公開日2006-10-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism.
Nature, 443, 2006