Author results

1MME
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THE CRYSTAL STRUCTURE OF AN ALL-RNA HAMMERHEAD RIBOZYME: A PROPOSED MECHANISM FOR RNA CATALYTIC CLEAVAGE
Descriptor:RNA HAMMERHEAD RIBOZYME
Authors:Scott, W.G., Finch, J.T., Klug, A.
Deposit date:1995-12-09
Release date:1996-02-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The crystal structure of an all-RNA hammerhead ribozyme: a proposed mechanism for RNA catalytic cleavage.
Cell(Cambridge,Mass.), 81, 1995
299D
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CAPTURING THE STRUCTURE OF A CATALYTIC RNA INTERMEDIATE: THE HAMMERHEAD RIBOZYME
Descriptor:RNA HAMMERHEAD RIBOZYME
Authors:Scott, W.G., Murray, J.B., Arnold, J.R.P., Stoddard, B.L., Klug, A.
Deposit date:1996-12-14
Release date:1997-01-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme.
Science, 274, 1996
300D
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CAPTURING THE STRUCTURE OF A CATALYTIC RNA INTERMEDIATE: RNA HAMMERHEAD RIBOZYME, MN(II)-SOAKED
Descriptor:RNA HAMMERHEAD RIBOZYME, MANGANESE (II) ION
Authors:Scott, W.G., Murray, J.B., Arnold, J.R.P., Stoddard, B.L., Klug, A.
Deposit date:1996-12-14
Release date:1997-01-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme.
Science, 274, 1996
301D
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CAPTURING THE STRUCTURE OF A CATALYTIC RNA INTERMEDIATE: RNA HAMMERHEAD RIBOZYME, MG(II)-SOAKED
Descriptor:RNA HAMMERHEAD RIBOZYME, MAGNESIUM ION
Authors:Scott, W.G., Murray, J.B., Arnold, J.R.P., Stoddard, B.L., Klug, A.
Deposit date:1996-12-14
Release date:1997-01-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme.
Science, 274, 1996
3ZD4
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FULL-LENGTH HAMMERHEAD RIBOZYME WITH G12A SUBSTITUTION AT THE GENERAL BASE POSITION
Descriptor:HAMMERHEAD RIBOZYME, ENZYME STRAND, SUBSTRATE STRAND
Authors:Scott, W.G., Schultz, E.
Deposit date:2012-11-24
Release date:2012-12-12
Last modified:2014-09-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and Catalytic Effects of an Invariant Purine Substitution in the Hammerhead Ribozyme: Implications for the Mechanism of Acid-Base Catalysis.
Acta Crystallogr.,Sect.D, 70, 2014
359D
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INHIBITION OF THE HAMMERHEAD RIBOZYME CLEAVAGE REACTION BY SITE-SPECIFIC BINDING OF TB(III)
Descriptor:RNA HAMMERHEAD RIBOZYME, TERBIUM(III) ION
Authors:Feig, A.L., Scott, W.G., Uhlenbeck, O.C.
Deposit date:1997-10-27
Release date:1997-11-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Inhibition of the hammerhead ribozyme cleavage reaction by site-specific binding of Tb.
Science, 279, 1998
1DUH
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CRYSTAL STRUCTURE OF THE CONSERVED DOMAIN IV OF E. COLI 4.5S RNA
Descriptor:4.5S RNA DOMAIN IV, LUTETIUM (III) ION, MAGNESIUM ION, ...
Authors:Jovine, L., Hainzl, T., Oubridge, C., Scott, W.G., Li, J., Sixma, T.K., Wonacott, A., Skarzynski, T., Nagai, K.
Deposit date:2000-01-17
Release date:2000-05-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the ffh and EF-G binding sites in the conserved domain IV of Escherichia coli 4.5S RNA.
Structure Fold.Des., 8, 2000
1IDC
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ISOCITRATE DEHYDROGENASE FROM E.COLI (MUTANT K230M), STEADY-STATE INTERMEDIATE COMPLEX DETERMINED BY LAUE CRYSTALLOGRAPHY
Descriptor:ISOCITRATE DEHYDROGENASE, MAGNESIUM ION, 2-OXALOSUCCINIC ACID
Authors:Bolduc, J.M., Dyer, D.H., Scott, W.G., Singer, P., Sweet, R.M., Koshland Junior, D.E., Stoddard, B.L.
Deposit date:1995-01-18
Release date:1996-03-08
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mutagenesis and Laue structures of enzyme intermediates: isocitrate dehydrogenase.
Science, 268, 1995
1IDE
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ISOCITRATE DEHYDROGENASE Y160F MUTANT STEADY-STATE INTERMEDIATE COMPLEX (LAUE DETERMINATION)
Descriptor:ISOCITRATE DEHYDROGENASE, MAGNESIUM ION, ISOCITRIC ACID, ...
Authors:Bolduc, J.M., Dyer, D.H., Scott, W.G., Singer, P., Sweet, R.M., Koshland Junior, D.E., Stoddard, B.L.
Deposit date:1995-01-18
Release date:1996-03-08
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mutagenesis and Laue structures of enzyme intermediates: isocitrate dehydrogenase.
Science, 268, 1995
1IDF
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ISOCITRATE DEHYDROGENASE K230M MUTANT APO ENZYME
Descriptor:ISOCITRATE DEHYDROGENASE
Authors:Bolduc, J.M., Dyer, D.H., Scott, W.G., Singer, P., Sweet, R.M., Koshland Junior, D.E., Stoddard, B.L.
Deposit date:1995-01-18
Release date:1996-03-08
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mutagenesis and Laue structures of enzyme intermediates: isocitrate dehydrogenase.
Science, 268, 1995
1NYI
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CROSSLINKED HAMMERHEAD RIBOZYME INITIAL STATE
Descriptor:5'-R(P*GP*UP*GP*GP*UP*CP*UP*GP*AP*UP*GP*AP*GP*GP*CP*C)-3', 5'-R(*GP*CP*CP*GP*AP*AP*AP*CP*UP*CP*GP*UP*AP*AP*GP*AP*GP*UP*CP*AP*CP*CP*AP*C)-3', COBALT (II) ION, ...
Authors:Dunham, C.M., Murray, J.B., Scott, W.G.
Deposit date:2003-02-12
Release date:2004-02-24
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:A helical twist-induced conformational switch activates cleavage in the hammerhead ribozyme.
J.Mol.Biol., 332, 2003
1Q29
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HAMMERHEAD RIBOZYME WITH 5'-5' G-G LINKAGE: CONFORMATIONAL CHANGE EXPERIMENT
Descriptor:5'-R(*GP*GP*UP*GP*GP*UP*CP*UP*GP*AP*UP*GP*AP*GP*GP*CP*C)-3', Ribozyme, COBALT (II) ION
Authors:Dunham, C.M., Murray, J.B., Scott, W.G.
Deposit date:2003-07-23
Release date:2004-02-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:A helical twist-induced conformational switch activates cleavage in the hammerhead ribozyme.
J.Mol.Biol., 332, 2003
1XJR
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THE STRUCTURE OF A RIGOROUSLY CONSERVED RNA ELEMENT WITHIN THE SARS VIRUS GENOME
Descriptor:s2m RNA, MAGNESIUM ION
Authors:Robertson, M.P., Igel, H., Baertsch, R., Haussler, D., Ares Jr., M., Scott, W.G.
Deposit date:2004-09-24
Release date:2005-02-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The structure of a rigorously conserved RNA element within the SARS virus genome
Plos Biol., 3, 2005
1Y28
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CRYSTAL STRUCTURE OF THE R220A METBJFIXL HEME DOMAIN
Descriptor:Sensor protein fixL, PROTOPORPHYRIN IX CONTAINING FE
Authors:Dunham, C.M., Dioum, E.M., Tuckerman, J.R., Gonzalez, G., Scott, W.G., Gilles-Gonzalez, M.A.
Deposit date:2004-11-21
Release date:2004-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A distal arginine in the oxygen-sensing heme-PAS domains is essential to ligand binding, signal transduction, and structure
Biochemistry, 42, 2003
2BX2
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CATALYTIC DOMAIN OF E. COLI RNASE E
Descriptor:RIBONUCLEASE E, RNA (5'-R(*UP*UP*UP*AP*CP*AP*GP*UP*AP*UP*UP* UP*GP*UP*U)-3'), MAGNESIUM ION, ...
Authors:Marcaida, M.J., Callaghan, A.J., Scott, W.G., Luisi, B.F.
Deposit date:2005-07-21
Release date:2005-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure of E. Coli Rnase E Catalytic Domain and Implications for RNA Processing and Turnover
Nature, 437, 2005
2C0B
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CATALYTIC DOMAIN OF E. COLI RNASE E IN COMPLEX WITH 13-MER RNA
Descriptor:RIBONUCLEASE E, 5'-R(*UP*UP*UP*AP*CP*AP*GP*UP*AP*UP*UP*UP*G)-3', MAGNESIUM ION, ...
Authors:Marcaida, M.J., Callaghan, A.J., Scott, W.G., Luisi, B.F.
Deposit date:2005-08-30
Release date:2005-10-14
Last modified:2015-05-20
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:Structure of E. Coli Rnase E Catalytic Domain and Implications for RNA Processing and Turnover
Nature, 437, 2005
2OEU
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FULL-LENGTH HAMMERHEAD RIBOZYME WITH MN(II) BOUND
Descriptor:Hammerhead Ribozyme, 5'-R(*GP*GP*CP*GP*UP*(OMC)P*CP*UP*GP*GP*(5BU)P*AP*UP*CP*CP*AP*AP*UP*CP*(DC))-3', MANGANESE (II) ION
Authors:Martick, M., Scott, W.G.
Deposit date:2007-01-01
Release date:2007-02-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Solvent structure and hammerhead ribozyme catalysis.
Chem.Biol., 15, 2008
2OIU
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L1 RIBOZYME LIGASE CIRCULAR ADDUCT
Descriptor:L1 Ribozyme RNA Ligase, MAGNESIUM ION
Authors:Robertson, M.P., Scott, W.G.
Deposit date:2007-01-11
Release date:2007-03-13
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The structural basis of ribozyme-catalyzed RNA assembly.
Science, 315, 2007
2QUS
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HAMMERHEAD RIBOZYME G12A MUTANT PRE-CLEAVAGE
Descriptor:Hammerhead ribozyme, MAGNESIUM ION
Authors:Chi, Y.I., Scott, W.G., Kim, S.H.
Deposit date:2007-08-06
Release date:2008-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Capturing hammerhead ribozyme structures in action by modulating general base catalysis.
Plos Biol., 6, 2008
2QUW
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HAMMERHEAD RIBOZYME G12A MUTANT AFTER CLEAVAGE
Descriptor:Hammerhead ribozyme, cleaved fragment, MAGNESIUM ION
Authors:Chi, Y.I., Scott, W.G., Kim, S.H.
Deposit date:2007-08-06
Release date:2008-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Capturing hammerhead ribozyme structures in action by modulating general base catalysis.
Plos Biol., 6, 2008
2VMK
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CRYSTAL STRUCTURE OF E. COLI RNASE E APOPROTEIN - CATALYTIC DOMAIN
Descriptor:RIBONUCLEASE E, SULFATE ION, ZINC ION
Authors:Koslover, D.J., Callaghan, A.J., Marcaida, M.J., Martick, M., Scott, W.G., Luisi, B.F.
Deposit date:2008-01-28
Release date:2008-07-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The Crystal Structure of the Escherichia Coli Rnase E Apoprotein and a Mechanism for RNA Degradation.
Structure, 16, 2008
2VRT
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CRYSTAL STRUCTURE OF E. COLI RNASE E POSSESSING M1 RNA FRAGMENTS - CATALYTIC DOMAIN
Descriptor:RIBONUCLEASE E, 5'-R(*UP*UP)-3', 5'-R(*UP*UP*GP)-3', ...
Authors:Koslover, D.J., Callaghan, A.J., Marcaida, M.J., Garman, E.F., Martick, M., Scott, W.G., Luisi, B.F.
Deposit date:2008-04-14
Release date:2008-07-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:The Crystal Structure of the Escherichia Coli Rnase E Apoprotein and a Mechanism for RNA Degradation.
Structure, 16, 2008
379D
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THE STRUCTURAL BASIS OF HAMMERHEAD RIBOZYME SELF-CLEAVAGE
Descriptor:RNA (5'-R(*GP*UP*GP*GP*UP*CP*UP*GP*AP*UP*GP*AP*GP*GP*CP*C)-3'), RNA (5'-R(*GP*GP*CP*CP*GP*AP*AP*AP*CP*UP*CP*GP*UP*AP*AP*GP*A P*GP*UP*CP*AP*CP*CP*AP*C)-3'), COBALT (II) ION
Authors:Murray, J.B., Terwey, D.P., Maloney, L., Karpeisky, A., Usman, N., Beigelman, L., Scott, W.G.
Deposit date:1998-02-05
Release date:1998-02-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The structural basis of hammerhead ribozyme self-cleavage.
Cell(Cambridge,Mass.), 92, 1998
3ZD5
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THE 2.2 A STRUCTURE OF A FULL-LENGTH CATALYTICALLY ACTIVE HAMMERHEAD RIBOZYME
Descriptor:HAMMERHEAD RIBOZYME, ENZYME STRAND, SUBSTRATE STRAND
Authors:Martick, M., Scott, W.G.
Deposit date:2012-11-24
Release date:2012-12-12
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Tertiary contacts distant from the active site prime a ribozyme for catalysis.
Cell, 126, 2006
3ZP8
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HIGH-RESOLUTION FULL-LENGTH HAMMERHEAD RIBOZYME
Descriptor:HAMMERHEAD RIBOZYME, ENZYME STRAND, SUBSTRATE STRAND, ...
Authors:Anderson, M., Schultz, E., Martick, M., Scott, W.G.
Deposit date:2013-02-26
Release date:2013-03-06
Last modified:2013-10-30
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Active-Site Monovalent Cations Revealed in a 1.55 A Resolution Hammerhead Ribozyme Structure
J.Mol.Biol., 425, 2013
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