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4A3Q
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THE 2.15 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS ALANINE RACEMASE
Descriptor:ALANINE RACEMASE 1, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION, ...
Authors:Scaletti, E.R., Luckner, S.R., Krause, K.L.
Deposit date:2011-10-04
Release date:2011-12-28
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural Features and Kinetic Characterization of Alanine Racemase from Staphylococcus Aureus (Mu50)
Acta Crystallogr.,Sect.D, 68, 2012
6SQW
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MOUSE DCTPASE IN COMPLEX WITH 5-ME-DCMP
Descriptor:dCTP pyrophosphatase 1, MAGNESIUM ION, 5-METHYL-2'-DEOXY-CYTIDINE-5'-MONOPHOSPHATE
Authors:Scaletti, E.R., Claesson, M., Helleday, H., Jemth, A.S., Stenmark, P.
Deposit date:2019-09-04
Release date:2020-01-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The first structure of an active mammalian dCTPase and its complexes with substrate analogues and products.
J.Mol.Biol., 2020
6SQY
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MOUSE DCTPASE IN COMPLEX WITH DCMP
Descriptor:dCTP pyrophosphatase 1, MAGNESIUM ION, 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE
Authors:Scaletti, E.R., Claesson, M., Helleday, H., Jemth, A.S., Stenmark, P.
Deposit date:2019-09-04
Release date:2020-01-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The first structure of an active mammalian dCTPase and its complexes with substrate analogues and products.
J.Mol.Biol., 2020
6SQZ
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MOUSE DCTPASE IN COMPLEX WITH DCMPNPP
Descriptor:dCTP pyrophosphatase 1, MAGNESIUM ION, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine
Authors:Scaletti, E.R., Claesson, M., Helleday, H., Jemth, A.S., Stenmark, P.
Deposit date:2019-09-04
Release date:2020-01-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The first structure of an active mammalian dCTPase and its complexes with substrate analogues and products.
J.Mol.Biol., 2020
6TVE
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UNLIGANDED HUMAN CD73 (5'-NUCLEOTIDASE) IN THE OPEN STATE
Descriptor:5'-nucleotidase, CALCIUM ION, ZINC ION, ...
Authors:Scaletti, E., Strater, N.
Deposit date:2020-01-09
Release date:2020-02-19
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:2-Substituted alpha , beta Methylene-ADP Derivatives: Potent Competitive Ecto-5'-nucleotidase (CD73) Inhibitors with Variable Binding Modes.
J.Med.Chem., 2020
6TVX
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HUMAN CD73 (ECTO 5'-NUCLEOTIDASE) IN COMPLEX WITH PSB12676 (AN AOPCP DERIVATIVE, COMPOUND 9 IN PAPER) IN THE CLOSED STATE
Descriptor:5'-nucleotidase, ZINC ION, [[(2~{R},3~{S},4~{R},5~{R})-5-[2,6-bis(azanyl)purin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]methylphosphonic acid
Authors:Pippel, J., Strater, N.
Deposit date:2020-01-10
Release date:2020-02-19
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:2-Substituted alpha , beta Methylene-ADP Derivatives: Potent Competitive Ecto-5'-nucleotidase (CD73) Inhibitors with Variable Binding Modes.
J.Med.Chem., 2020
6TW0
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HUMAN CD73 (ECTO 5'-NUCLEOTIDASE) IN COMPLEX WITH PSB12690 (AN AOPCP DERIVATIVE, COMPOUND 10 IN PUBLICATION) IN THE CLOSED STATE
Descriptor:5'-nucleotidase, ZINC ION, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-azanyl-2-oxidanylidene-3~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]methylphosphonic acid
Authors:Pippel, J., Strater, N.
Deposit date:2020-01-10
Release date:2020-02-19
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:2-Substituted alpha , beta Methylene-ADP Derivatives: Potent Competitive Ecto-5'-nucleotidase (CD73) Inhibitors with Variable Binding Modes.
J.Med.Chem., 2020
6TWA
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HUMAN CD73 (ECTO 5'-NUCLEOTIDASE) IN COMPLEX WITH PSB12646 (AN AOPCP DERIVATIVE, COMPOUND 20 IN PUBLICATION) IN THE CLOSED STATE
Descriptor:5'-nucleotidase, ZINC ION, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-azanyl-2-diazanyl-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]methylphosphonic acid, ...
Authors:Pippel, J., Strater, N.
Deposit date:2020-01-12
Release date:2020-02-19
Method:X-RAY DIFFRACTION (2 Å)
Cite:2-Substituted alpha , beta Methylene-ADP Derivatives: Potent Competitive Ecto-5'-nucleotidase (CD73) Inhibitors with Variable Binding Modes.
J.Med.Chem., 2020
6TWF
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HUMAN CD73 (ECTO 5'-NUCLEOTIDASE) IN COMPLEX WITH PSB12604 (AN AOPCP DERIVATIVE, COMPOUND 21 IN PUBLICATION) IN THE CLOSED STATE
Descriptor:5'-nucleotidase, ZINC ION, CALCIUM ION, ...
Authors:Pippel, J., Strater, N.
Deposit date:2020-01-13
Release date:2020-02-19
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:2-Substituted alpha , beta Methylene-ADP Derivatives: Potent Competitive Ecto-5'-nucleotidase (CD73) Inhibitors with Variable Binding Modes.
J.Med.Chem., 2020