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3P4P
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CRYSTAL STRUCTURE OF MENAQUINOL:FUMARATE OXIDOREDUCTASE IN COMPLEX WITH FUMARATE
Descriptor:Fumarate reductase flavoprotein subunit, Fumarate reductase iron-sulfur protein, Fumarate reductase subunit C, ...
Authors:Tomasiak, T.M., Archuleta, T.L., Andr ll, J., Luna-Ch vez, C., Davis, T.A., Sarwar, M., Ham, A.J., McDonald, W.H., Yankowskaya, V., Stern, H.A., Johnston, J.N., Maklashina, E., Cecchini, G., Iverson, T.M.
Deposit date:2010-10-06
Release date:2010-12-01
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Geometric restraint drives on- and off-pathway catalysis by the Escherichia coli menaquinol:fumarate reductase.
J.Biol.Chem., 286, 2011
3P4Q
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CRYSTAL STRUCTURE OF MENAQUINOL:OXIDOREDUCTASE IN COMPLEX WITH OXALOACETATE
Descriptor:Fumarate reductase flavoprotein subunit, Fumarate reductase iron-sulfur protein, Fumarate reductase subunit C, ...
Authors:Tomasiak, T.M., Archuleta, T.L., Andrell, J., Luna-Chavez, C., Davis, T.A., Sarwar, M., Ham, A.J., McDonald, W.H., Yankowskaya, V., Stern, H.A., Johnston, J.N., Maklashina, E., Cecchini, G., Iverson, T.M.
Deposit date:2010-10-06
Release date:2010-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Geometric restraint drives on- and off-pathway catalysis by the Escherichia coli menaquinol:fumarate reductase.
J.Biol.Chem., 286, 2011
3P4R
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CRYSTAL STRUCTURE OF MENAQUINOL:FUMARATE OXIDOREDUCTASE IN COMPLEX WITH GLUTARATE
Descriptor:Fumarate reductase flavoprotein subunit, Fumarate reductase iron-sulfur subunit, Fumarate reductase subunit C, ...
Authors:Tomasiak, T.M., Archuleta, T.L., Andrell, J., Luna-Chavez, C., Davis, T.A., Sarwar, M., Ham, A.J., McDonald, W.H., Yankowskaya, V., Stern, H.A., Johnston, J.N., Maklashina, E., Cecchini, G., Iverson, T.M.
Deposit date:2010-10-07
Release date:2010-11-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Geometric restraint drives on- and off-pathway catalysis by the Escherichia coli menaquinol:fumarate reductase.
J.Biol.Chem., 286, 2011
3P4S
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CRYSTAL STRUCTURE OF MENAQUINOL:FUMARATE OXIDOREDUCTASE IN COMPLEX WITH A 3-NITROPROPIONATE ADDUCT
Descriptor:Fumarate reductase flavoprotein subunit, Fumarate reductase iron-sulfur subunit, Fumarate reductase subunit C, ...
Authors:Tomasiak, T.M., Archuleta, T.L., Andrell, J., Luna-Chavez, C., Davis, T.A., Sarwar, M., Ham, A.J., McDonald, W.H., Yankowskaya, V., Stern, H.A., Johnston, J.N., Maklashina, E., Cecchini, G., Iverson, T.M.
Deposit date:2010-10-07
Release date:2010-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Geometric restraint drives on- and off-pathway catalysis by the Escherichia coli menaquinol:fumarate reductase.
J.Biol.Chem., 286, 2011
4KX6
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PLASTICITY OF THE QUINONE-BINDING SITE OF THE COMPLEX II HOMOLOG QUINOL:FUMARATE REDUCTASE
Descriptor:Fumarate reductase flavoprotein subunit, Fumarate reductase (Anaerobic), Fe-S subunit, ...
Authors:Singh, P.K., Sarwar, M., Maklashina, E., Kotlyar, V., Rajagukguk, S., Tomasiak, T.M., Cecchini, G., Iverson, T.M.
Deposit date:2013-05-24
Release date:2013-07-17
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Plasticity of the Quinone-binding Site of the Complex II Homolog Quinol:Fumarate Reductase.
J.Biol.Chem., 288, 2013
4N0D
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CRYSTAL STRUCTURE OF THE K345L VARIANT OF THE GI ALPHA1 SUBUNIT BOUND TO GTPGAMMAS
Descriptor:Guanine nucleotide-binding protein G(i) subunit alpha-1, SULFITE ION, MAGNESIUM ION, ...
Authors:Thaker, T.M., Preininger, A.M., Sarwar, M., Hamm, H.E., Iverson, T.M.
Deposit date:2013-10-01
Release date:2014-03-12
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:A Transient Interaction between the Phosphate Binding Loop and Switch I Contributes to the Allosteric Network between Receptor and Nucleotide in G alpha i1.
J.Biol.Chem., 289, 2014
4N0E
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CRYSTAL STRUCTURE OF THE K345L VARIANT OF THE GI ALPHA1 SUBUNIT BOUND TO GDP
Descriptor:Guanine nucleotide-binding protein G(i) subunit alpha-1, GUANOSINE-5'-DIPHOSPHATE, SULFATE ION
Authors:Thaker, T.M., Preininger, A.M., Sarwar, M., Hamm, H.E., Iverson, T.M.
Deposit date:2013-10-01
Release date:2014-03-12
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A Transient Interaction between the Phosphate Binding Loop and Switch I Contributes to the Allosteric Network between Receptor and Nucleotide in G alpha i1.
J.Biol.Chem., 289, 2014
4XAA
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CRYSTAL STRUCTURE OF AVIO1 FROM STREPTOMYCES VIRIDOCHROMOGENES TUE57
Descriptor:Putative oxygenase, NICKEL (II) ION
Authors:McCulloch, K.M., McCranie, E.K., Sarwar, M., Mathieu, J.L., Gitschlag, B.L., Du, Y., Bachmann, B.O., Iverson, T.M.
Deposit date:2014-12-13
Release date:2015-08-05
Last modified:2015-09-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Oxidative cyclizations in orthosomycin biosynthesis expand the known chemistry of an oxygenase superfamily.
Proc.Natl.Acad.Sci.USA, 112, 2015
4XAB
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CRYSTAL STRUCTURE OF EVDO2 FROM MICROMONOSPORA CARBONACEA VAR. AURANTIACA
Descriptor:EvdO2, NICKEL (II) ION, IMIDAZOLE
Authors:McCulloch, K.M., McCranie, E.K., Sarwar, M., Mathieu, J.L., Gitschlag, B.L., Du, Y., Bachmann, B.O., Iverson, T.M.
Deposit date:2014-12-13
Release date:2015-08-05
Last modified:2015-09-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Oxidative cyclizations in orthosomycin biosynthesis expand the known chemistry of an oxygenase superfamily.
Proc.Natl.Acad.Sci.USA, 112, 2015
4XAC
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CRYSTAL STRUCTURE OF EVDO2 FROM MICROMONOSPORA CARBONACEA VAR. AURANTIACA COMPLEXED WITH 2-OXOGLUTARATE
Descriptor:EvdO2, NICKEL (II) ION, IMIDAZOLE, ...
Authors:McCulloch, K.M., McCranie, E.K., Sarwar, M., Mathieu, J.L., Gitschlag, B.L., Du, Y., Bachmann, B.O., Iverson, T.M.
Deposit date:2014-12-13
Release date:2015-08-05
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Oxidative cyclizations in orthosomycin biosynthesis expand the known chemistry of an oxygenase superfamily.
Proc.Natl.Acad.Sci.USA, 112, 2015
4XBZ
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CRYSTAL STRUCTURE OF EVDO1 FROM MICROMONOSPORA CARBONACEA VAR. AURANTIACA
Descriptor:EvdO1, NICKEL (II) ION, GLYCEROL
Authors:McCulloch, K.M., McCranie, E.K., Sarwar, M., Mathieu, J.L., Gitschlag, B.L., Du, Y., Bachmann, B.O., Iverson, T.M.
Deposit date:2014-12-17
Release date:2015-08-05
Last modified:2015-09-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Oxidative cyclizations in orthosomycin biosynthesis expand the known chemistry of an oxygenase superfamily.
Proc.Natl.Acad.Sci.USA, 112, 2015
4XC9
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CRYSTAL STRUCTURE OF APO HYGX FROM STREPTOMYCES HYGROSCOPICUS
Descriptor:oxidase/hydroxylase, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:McCulloch, K.M., McCranie, E.K., Sarwar, M., Mathieu, J.L., Gitschlag, B.L., Du, Y., Bachmann, B.O., Iverson, T.M.
Deposit date:2014-12-17
Release date:2015-08-05
Last modified:2015-09-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Oxidative cyclizations in orthosomycin biosynthesis expand the known chemistry of an oxygenase superfamily.
Proc.Natl.Acad.Sci.USA, 112, 2015
4XCA
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CRYSTAL STRUCTURE OF HYGX FROM STREPTOMYCES HYGROSCOPICUS WITH NICKEL AND 2-OXOGLUTARATE BOUND
Descriptor:oxidase/hydroxylase, NICKEL (II) ION, 2-OXOGLUTARIC ACID, ...
Authors:McCulloch, K.M., McCranie, E.K., Sarwar, M., Mathieu, J.L., Gitschlag, B.L., Du, Y., Bachmann, B.O., Iverson, T.M.
Deposit date:2014-12-17
Release date:2015-08-05
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.295 Å)
Cite:Oxidative cyclizations in orthosomycin biosynthesis expand the known chemistry of an oxygenase superfamily.
Proc.Natl.Acad.Sci.USA, 112, 2015
4XCB
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CRYSTAL STRUCTURE OF HYGX FROM STREPTOMYCES HYGROSCOPICUS WITH NICKEL, 2-OXOGLUTARATE, AND HYGROMYCIN B BOUND
Descriptor:oxidase/hydroxylase, NICKEL (II) ION, 2-OXOGLUTARIC ACID, ...
Authors:McCulloch, K.M., McCranie, E.K., Sarwar, M., Mathieu, J.L., Gitschlag, B.L., Du, Y., Bachmann, B.O., Iverson, T.M.
Deposit date:2014-12-17
Release date:2015-08-05
Last modified:2015-09-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Oxidative cyclizations in orthosomycin biosynthesis expand the known chemistry of an oxygenase superfamily.
Proc.Natl.Acad.Sci.USA, 112, 2015
4ZPI
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CRYSTAL STRUCTURE OF HYGX FROM STREPTOMYCES HYGROSCOPICUS WITH IRON BOUND
Descriptor:Putative oxidase/hydroxylase, FE (II) ION, SUCCINIC ACID
Authors:McCulloch, K.M., McCranie, E.K., Sarwar, M., Mathieu, J.L., Gitschlag, B.L., Du, Y., Bachmann, B.O., Iverson, T.M.
Deposit date:2015-05-07
Release date:2015-08-05
Last modified:2015-09-23
Method:X-RAY DIFFRACTION (2.504 Å)
Cite:Oxidative cyclizations in orthosomycin biosynthesis expand the known chemistry of an oxygenase superfamily.
Proc.Natl.Acad.Sci.USA, 112, 2015
5HMS
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X-RAY STRUCTURE OF HUMAN RECOMBINANT 5-AMINOLAEVULINIC ACID DEHYDRATASE (HRALAD).
Descriptor:Delta-aminolevulinic acid dehydratase, ZINC ION
Authors:Butler, D., Erskine, P.T., Cooper, J.B., Shoolingin-Jordan, P.M.
Deposit date:2016-01-17
Release date:2016-01-27
Last modified:2017-03-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural studies of substrate and product complexes of 5-aminolaevulinic acid dehydratase from humans, Escherichia coli and the hyperthermophile Pyrobaculum calidifontis.
Acta Crystallogr D Struct Biol, 73, 2017
5HNR
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THE X-RAY STRUCTURE OF OCTAMERIC HUMAN NATIVE 5-AMINOLAEVULINIC ACID DEHYDRATASE.
Descriptor:Delta-aminolevulinic acid dehydratase, ZINC ION, SULFATE ION, ...
Authors:Mills-Davies, N.L., Thompson, D., Shoolingin-Jordan, P.M., Erskine, P.T., Cooper, J.B.
Deposit date:2016-01-18
Release date:2016-01-27
Last modified:2017-01-25
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:Structural studies of substrate and product complexes of 5-aminolaevulinic acid dehydratase from humans, Escherichia coli and the hyperthermophile Pyrobaculum calidifontis.
Acta Crystallogr D Struct Biol, 73, 2017
5LZL
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PYROBACULUM CALIDIFONTIS 5-AMINOLAEVULINIC ACID DEHYDRATASE
Descriptor:Delta-aminolevulinic acid dehydratase, ZINC ION
Authors:Azim, N., Erskine, P.T., Guo, J., Cooper, J.B.
Deposit date:2016-09-30
Release date:2016-10-12
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (3.47 Å)
Cite:Structural studies of substrate and product complexes of 5-aminolaevulinic acid dehydratase from humans, Escherichia coli and the hyperthermophile Pyrobaculum calidifontis.
Acta Crystallogr D Struct Biol, 73, 2017
5MHB
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PRODUCT-COMPLEX OF E.COLI 5-AMINO LAEVULINIC ACID DEHYDRATASE
Descriptor:Delta-aminolevulinic acid dehydratase, 3-[5-(AMINOMETHYL)-4-(CARBOXYMETHYL)-1H-PYRROL-3-YL]PROPANOIC ACID, ZINC ION, ...
Authors:Norton, E., Erskine, P.T., Shoolingin-Jordan, P.M., Cooper, J.B.
Deposit date:2016-11-23
Release date:2016-12-07
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural studies of substrate and product complexes of 5-aminolaevulinic acid dehydratase from humans, Escherichia coli and the hyperthermophile Pyrobaculum calidifontis.
Acta Crystallogr D Struct Biol, 73, 2017
1AW5
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5-AMINOLEVULINATE DEHYDRATASE FROM SACCHAROMYCES CEREVISIAE
Descriptor:5-AMINOLEVULINATE DEHYDRATASE, ZINC ION
Authors:Erskine, P.T., Cooper, J.B., Wood, S.P.
Deposit date:1997-10-09
Release date:1998-10-21
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:X-ray structure of 5-aminolaevulinate dehydratase, a hybrid aldolase.
Nat.Struct.Biol., 4, 1997
1B4E
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X-RAY STRUCTURE OF 5-AMINOLEVULINIC ACID DEHYDRATASE COMPLEXED WITH THE INHIBITOR LEVULINIC ACID
Descriptor:PROTEIN (5-AMINOLEVULINIC ACID DEHYDRATASE), SULFATE ION, ZINC ION, ...
Authors:Erskine, P.T., Cooper, J.B., Lewis, G., Spencer, P., Wood, S.P., Shoolingin-Jordan, P.M.
Deposit date:1998-12-19
Release date:1999-12-17
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structure of 5-aminolevulinic acid dehydratase from Escherichia coli complexed with the inhibitor levulinic acid at 2.0 A resolution.
Biochemistry, 38, 1999
3EQ1
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THE CRYSTAL STRUCTURE OF HUMAN PORPHOBILINOGEN DEAMINASE AT 2.8A RESOLUTION
Descriptor:Porphobilinogen deaminase, 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, SULFATE ION
Authors:Kolstoe, S.E., Gill, R., Mohammed, F., Wood, S.P.
Deposit date:2008-09-30
Release date:2009-03-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of human porphobilinogen deaminase at 2.8 A: the molecular basis of acute intermittent porphyria
Biochem.J., 420, 2009