4XCA

Crystal Structure of HygX from Streptomyces hygroscopicus with nickel and 2-oxoglutarate bound

Summary for 4XCA

Descriptoroxidase/hydroxylase, NICKEL (II) ION, 2-OXOGLUTARIC ACID, ... (6 entities in total)
Functional Keywordsoxidoreductase, double stranded beta helix
Biological sourceStreptomyces hygroscopicus subsp. hygroscopicus
Total number of polymer chains4
Total molecular weight117265.93
Authors
McCulloch, K.M.,McCranie, E.K.,Sarwar, M.,Mathieu, J.L.,Gitschlag, B.L.,Du, Y.,Bachmann, B.O.,Iverson, T.M. (deposition date: 2014-12-17, release date: 2015-08-05, Last modification date: 2017-09-06)
Primary citation
McCulloch, K.M.,McCranie, E.K.,Smith, J.A.,Sarwar, M.,Mathieu, J.L.,Gitschlag, B.L.,Du, Y.,Bachmann, B.O.,Iverson, T.M.
Oxidative cyclizations in orthosomycin biosynthesis expand the known chemistry of an oxygenase superfamily.
Proc.Natl.Acad.Sci.USA, 112:11547-11552, 2015
PubMed: 26240321 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1500964112
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.295 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.23720.1%0.9%1.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution