4XCA

Crystal Structure of HygX from Streptomyces hygroscopicus with nickel and 2-oxoglutarate bound

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016706	molecular_function	2-oxoglutarate-dependent dioxygenase activity
A	0046872	molecular_function	metal ion binding
B	0016706	molecular_function	2-oxoglutarate-dependent dioxygenase activity
B	0046872	molecular_function	metal ion binding
C	0016706	molecular_function	2-oxoglutarate-dependent dioxygenase activity
C	0046872	molecular_function	metal ion binding
D	0016706	molecular_function	2-oxoglutarate-dependent dioxygenase activity
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue NI A 301

Chain	Residue
A	HIS102
A	HIS206
A	AKG302
A	HOH458
A	HOH459

---

site_id	AC2
Number of Residues	13
Details	binding site for residue AKG A 302

Chain	Residue
A	LYS137
A	TYR141
A	HIS206
A	THR208
A	ARG217
A	LEU219
A	NI301
A	HOH459
A	HOH511
A	TYR89
A	LEU91
A	LEU99
A	HIS102

---

site_id	AC3
Number of Residues	4
Details	binding site for residue TRS A 303

Chain	Residue
A	ASP249
A	HIS250
A	ASP255
A	HOH493

---

site_id	AC4
Number of Residues	5
Details	binding site for residue NI B 301

Chain	Residue
B	HIS102
B	HIS206
B	AKG302
B	HOH462
B	HOH463

---

site_id	AC5
Number of Residues	14
Details	binding site for residue AKG B 302

Chain	Residue
B	TYR89
B	LEU91
B	LEU99
B	HIS102
B	LYS137
B	TYR141
B	HIS206
B	THR208
B	ARG217
B	NI301
B	HOH462
B	HOH463
B	HOH464
B	HOH465

---

site_id	AC6
Number of Residues	1
Details	binding site for residue CS B 303

Chain	Residue
B	ASP249

---

site_id	AC7
Number of Residues	5
Details	binding site for residue NI C 301

Chain	Residue
C	HIS102
C	HIS206
C	AKG302
C	HOH492
C	HOH493

---

site_id	AC8
Number of Residues	11
Details	binding site for residue AKG C 302

Chain	Residue
C	TYR89
C	LEU91
C	LYS137
C	TYR141
C	HIS206
C	THR208
C	ARG217
C	LEU219
C	NI301
C	HOH455
C	HOH493

---

site_id	AC9
Number of Residues	1
Details	binding site for residue CS C 303

Chain	Residue
C	ASP249

---

site_id	AD1
Number of Residues	5
Details	binding site for residue NI D 301

Chain	Residue
D	HIS102
D	HIS206
D	AKG302
D	HOH495
D	HOH496

---

site_id	AD2
Number of Residues	12
Details	binding site for residue AKG D 302

Chain	Residue
D	TYR89
D	LEU91
D	LEU99
D	HIS102
D	LYS137
D	TYR141
D	HIS206
D	THR208
D	ARG217
D	NI301
D	HOH469
D	HOH496

---

site_id	AD3
Number of Residues	1
Details	binding site for residue CS D 303

Chain	Residue
D	ASP249

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