Author results

6DR3
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CRYSTAL STRUCTURE OF E. COLI LPOA AMINO TERMINAL DOMAIN
Descriptor:Penicillin-binding protein activator LpoA
Authors:Kelley, A.C., Saper, M.A.
Deposit date:2018-06-11
Release date:2019-05-08
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:Crystal structures of the amino-terminal domain of LpoA from Escherichia coli and Haemophilus influenzae.
Acta Crystallogr.,Sect.F, 75, 2019
6DCJ
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LPOA N-TERMINAL DOMAIN FROM HAEMOPHILUS INFLUENZAE; MONOCLINIC FORM AT 1.35 A RESOLUTION
Descriptor:Penicillin-binding protein activator LpoA, CHLORIDE ION
Authors:Vijayalakshmi, J., Saper, M.A.
Deposit date:2018-05-07
Release date:2019-05-01
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Crystal structures of the amino-terminal domain of LpoA from Escherichia coli and Haemophilus influenzae.
Acta Crystallogr.,Sect.F, 75, 2019
5KCN
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CRYSTAL STRUCTURE OF FULL-LENGTH LPOA FROM HAEMOPHILUS INFLUENZAE AT 1.97 ANGSTROM RESOLUTION
Descriptor:Penicillin-binding protein activator LpoA, CHLORIDE ION
Authors:Sathiyamoorthy, K., Saper, M.A.
Deposit date:2016-06-06
Release date:2017-09-13
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.965 Å)
Cite:Structural analyses of the Haemophilus influenzae peptidoglycan synthase activator LpoA suggest multiple conformations in solution.
J. Biol. Chem., 292, 2017
5VAT
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HAEMOPHILUS INFLUENZAE LPOA: MONOCLINIC FORM (MON2) WITH 2 MOLECULES PER A.U.
Descriptor:Penicillin-binding protein activator LpoA
Authors:Saper, M.A., Sathiyamoorthy, K.
Deposit date:2017-03-27
Release date:2017-09-13
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural analyses of the Haemophilus influenzae peptidoglycan synthase activator LpoA suggest multiple conformations in solution.
J. Biol. Chem., 292, 2017
5VBG
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CRYSTAL STRUCTURE OF FULL-LENGTH LPOA, MONOCLINIC FORM 1, FROM HAEMOPHILUS INFLUENZAE
Descriptor:Penicillin-binding protein activator LpoA, CHLORIDE ION
Authors:Sathiyamoorthy, K., Saper, M.A.
Deposit date:2017-03-29
Release date:2017-09-13
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural analyses of the Haemophilus influenzae peptidoglycan synthase activator LpoA suggest multiple conformations in solution.
J. Biol. Chem., 292, 2017
4P29
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CRYSTAL STRUCTURE OF THE LPOA N-TERMINAL DOMAIN FROM HAEMOPHILUS INFLUENZAE
Descriptor:LpoA, SULFATE ION, GLYCEROL, ...
Authors:Vijayalakshmi, J., Saper, M.A.
Deposit date:2014-03-02
Release date:2015-03-04
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.950065 Å)
Cite:Structural analyses of the Haemophilus influenzae peptidoglycan synthase activator LpoA suggest multiple conformations in solution
J.Biol.Chem., 2017
3P42
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STRUCTURE OF GFCC (YMCB), PROTEIN ENCODED BY THE E. COLI GROUP 4 CAPSULE OPERON
Descriptor:Predicted protein, SULFATE ION
Authors:Saper, M.A., Sathiyamoorthy, K.
Deposit date:2010-10-05
Release date:2011-04-06
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:The Crystal Structure of Escherichia coli Group 4 Capsule Protein GfcC Reveals a Domain Organization Resembling That of Wza.
Biochemistry, 50, 2011
3CKM
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LPOA (YRAM) C-DOMAIN FROM HAEMOPHILUS INFLUENZAE, A REGULATOR OF PBP1A
Descriptor:YRAM (HI1655), SULFATE ION, BETA-MERCAPTOETHANOL
Authors:Vijayalakshmi, J., Saper, M.A.
Deposit date:2008-03-16
Release date:2008-05-13
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structure of YraM, a protein essential for growth of Haemophilus influenzae.
Proteins, 73, 2008
2I42
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CRYSTAL STRUCTURE OF YERSINIA PROTEIN TYROSINE PHOSPHATASE COMPLEXED WITH VANADATE, A TRANSITION STATE ANALOGUE
Descriptor:Tyrosine-protein phosphatase, VANADATE ION
Authors:Vijayalakshmi, J., Saper, M.A.
Deposit date:2006-08-21
Release date:2006-09-19
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Yersinia protein tyrosine phosphatase complexed with vanadate, a transition state analogue
To be Published
1Z15
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CRYSTAL STRUCTURE ANALYSIS OF PERIPLASMIC LEU/ILE/VAL-BINDING PROTEIN IN SUPEROPEN FORM
Descriptor:Leu/Ile/Val-binding protein
Authors:Trakhanov, S.D., Vyas, N.K., Kristensen, D.M., Ma, J., Quiocho, F.A.
Deposit date:2005-03-03
Release date:2005-10-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Ligand-free and -bound structures of the binding protein (LivJ) of the Escherichia coli ABC leucine/isoleucine/valine transport system: trajectory and dynamics of the interdomain rotation and ligand specificity.
Biochemistry, 44, 2005
1Z16
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CRYSTAL STRUCTURE ANALYSIS OF PERIPLASMIC LEU/ILE/VAL-BINDING PROTEIN WITH BOUND LEUCINE
Descriptor:Leu/Ile/Val-binding protein, CADMIUM ION, LEUCINE
Authors:Trakhanov, S.D., Vyas, N.K., Kristensen, D.M., Ma, J., Quiocho, F.A.
Deposit date:2005-03-03
Release date:2005-10-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Ligand-free and -bound structures of the binding protein (LivJ) of the Escherichia coli ABC leucine/isoleucine/valine transport system: trajectory and dynamics of the interdomain rotation and ligand specificity.
Biochemistry, 44, 2005
1Z17
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CRYSTAL STRUCTURE ANALYSIS OF PERIPLASMIC LEU/ILE/VAL-BINDING PROTEIN WITH BOUND LIGAND ISOLEUCINE
Descriptor:Leu/Ile/Val-binding protein, ISOLEUCINE, (4R)-2-METHYLPENTANE-2,4-DIOL
Authors:Trakhanov, S.D., Vyas, N.K., Kristensen, D.M., Ma, J., Quiocho, F.A.
Deposit date:2005-03-03
Release date:2005-10-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Ligand-free and -bound structures of the binding protein (LivJ) of the Escherichia coli ABC leucine/isoleucine/valine transport system: trajectory and dynamics of the interdomain rotation and ligand specificity.
Biochemistry, 44, 2005
1Z18
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CRYSTAL STRUCTURE ANALYSIS OF PERIPLASMIC LEU/ILE/VAL-BINDING PROTEIN WITH BOUND VALINE
Descriptor:Leu/Ile/Val-binding protein, CADMIUM ION, VALINE
Authors:Trakhanov, S.D., Vyas, N.K., Kristensen, D.M., Ma, J., Quiocho, F.A.
Deposit date:2005-03-03
Release date:2005-10-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Ligand-free and -bound structures of the binding protein (LivJ) of the Escherichia coli ABC leucine/isoleucine/valine transport system: trajectory and dynamics of the interdomain rotation and ligand specificity.
Biochemistry, 44, 2005
1XXP
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YERSINIA YOPH (RESIDUES 163-468) C403S BINDS PHOSPHOTYROSYL PEPTIDE AT TWO SITES
Descriptor:Protein-tyrosine phosphatase yopH, Hexapeptide ASP-ALA-ASP-GLU-PTR-CLE
Authors:Ivanov, M.I., Stuckey, J.A., Schubert, H.L., Saper, M.A., Bliska, J.B.
Deposit date:2004-11-07
Release date:2005-03-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Two substrate-targeting sites in the Yersinia protein tyrosine phosphatase co-operate to promote bacterial virulence
Mol.Microbiol., 55, 2005
1XXV
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YERSINIA YOPH (RESIDUES 163-468) BINDS PHOSPHONODIFLUOROMETHYL-PHE CONTAINING HEXAPEPTIDE AT TWO SITES
Descriptor:Protein-tyrosine phosphatase yopH, Epidermal growth factor receptor derived peptide
Authors:Ivanov, M.I., Stuckey, J.A., Schubert, H.L., Saper, M.A., Bliska, J.B.
Deposit date:2004-11-08
Release date:2005-03-22
Last modified:2011-09-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Two substrate-targeting sites in the Yersinia protein tyrosine phosphatase co-operate to promote bacterial virulence
Mol.Microbiol., 55, 2005
1M0V
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NMR STRUCTURE OF THE TYPE III SECRETORY DOMAIN OF YERSINIA YOPH COMPLEXED WITH THE SKAP-HOM PHOSPHO-PEPTIDE N-ACETYL-DEPYDDPF-NH2
Descriptor:PROTEIN-TYROSINE PHOSPHATASE YOPH, SKAP55 homologue
Authors:Khandelwal, P., Keliikuli, K., Smith, C.L., Saper, M.A., Zuiderweg, E.R.P.
Deposit date:2002-06-14
Release date:2002-07-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure and phosphopeptide binding to the N-terminal domain of Yersinia YopH: comparison with a crystal structure
Biochemistry, 41, 2002
1K46
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CRYSTAL STRUCTURE OF THE TYPE III SECRETORY DOMAIN OF YERSINIA YOPH REVEALS A DOMAIN-SWAPPED DIMER
Descriptor:PROTEIN-TYROSINE PHOSPHATASE YOPH
Authors:Smith, C.L., Khandelwal, P., Keliikuli, K., Zuiderweg, E.R.P., Saper, M.A.
Deposit date:2001-10-05
Release date:2001-11-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the type III secretion and substrate-binding domain of Yersinia YopH phosphatase.
Mol.Microbiol., 42, 2001
1HW7
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HSP33, HEAT SHOCK PROTEIN WITH REDOX-REGULATED CHAPERONE ACTIVITY
Descriptor:HEAT SHOCK PROTEIN HSP33, SULFATE ION, ZINC ION, ...
Authors:Vijayalakshmi, J., Mukhergee, M.K., Graumann, J., Jakob, U., Saper, M.A.
Deposit date:2001-01-09
Release date:2001-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The 2.2 A crystal structure of Hsp33: a heat shock protein with redox-regulated chaperone activity.
Structure, 9, 2001
1EIZ
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FTSJ RNA METHYLTRANSFERASE COMPLEXED WITH S-ADENOSYLMETHIONINE
Descriptor:FTSJ, S-ADENOSYLMETHIONINE
Authors:Bugl, H., Fauman, E.B., Staker, B.L., Zheng, F., Kushner, S.R., Saper, M.A., Bardwell, J.C.A., Jakob, U.
Deposit date:2000-02-29
Release date:2000-08-30
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:RNA methylation under heat shock control.
Mol.Cell, 6, 2000
1EJ0
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FTSJ RNA METHYLTRANSFERASE COMPLEXED WITH S-ADENOSYLMETHIONINE, MERCURY DERIVATIVE
Descriptor:FTSJ, MERCURY (II) ION, S-ADENOSYLMETHIONINE
Authors:Bugl, H., Fauman, E.B., Staker, B.L., Zheng, F., Kushner, S.R., Saper, M.A., Bardwell, J.C.A., Jakob, U.
Deposit date:2000-02-29
Release date:2000-08-30
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:RNA methylation under heat shock control.
Mol.Cell, 6, 2000
1DM9
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HEAT SHOCK PROTEIN 15 KD
Descriptor:HYPOTHETICAL 15.5 KD PROTEIN IN MRCA-PCKA INTERGENIC REGION, SULFATE ION
Authors:Staker, B.L., Korber, P., Bardwell, J.C.A., Saper, M.A.
Deposit date:1999-12-14
Release date:2000-02-18
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of Hsp15 reveals a novel RNA-binding motif.
EMBO J., 19, 2000
1C25
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HUMAN CDC25A CATALYTIC DOMAIN
Descriptor:CDC25A
Authors:Fauman, E.B., Cogswell, J.P., Lovejoy, B., Rocque, W.J., Holmes, W., Montana, V.G., Piwnica-Worms, H., Rink, M.J., Saper, M.A.
Deposit date:1998-04-17
Release date:1998-08-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the catalytic domain of the human cell cycle control phosphatase, Cdc25A.
Cell(Cambridge,Mass.), 93, 1998
1JLX
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AGGLUTININ IN COMPLEX WITH T-DISACCHARIDE
Descriptor:AGGLUTININ, BETA-D-GALACTOSE, N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE, ...
Authors:Transue, T.R., Smith, A.K., Mo, H., Goldstein, I.J., Saper, M.A.
Deposit date:1997-07-23
Release date:1997-12-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of benzyl T-antigen disaccharide bound to Amaranthus caudatus agglutinin.
Nat.Struct.Biol., 4, 1997
1JLY
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CRYSTAL STRUCTURE OF AMARANTHUS CAUDATUS AGGLUTININ
Descriptor:AGGLUTININ
Authors:Transue, T.R., Smith, A.K., Mo, H., Goldstein, I.J., Saper, M.A.
Deposit date:1997-07-23
Release date:1997-12-03
Last modified:2013-02-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of benzyl T-antigen disaccharide bound to Amaranthus caudatus agglutinin.
Nat.Struct.Biol., 4, 1997
1YTN
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HYDROLASE
Descriptor:YERSINIA PROTEIN TYROSINE PHOSPHATASE, NITRATE ION
Authors:Yuvaniyama, C., Fauman, E.B., Saper, M.A.
Deposit date:1996-05-01
Release date:1996-11-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The X-ray crystal structures of Yersinia tyrosine phosphatase with bound tungstate and nitrate. Mechanistic implications.
J.Biol.Chem., 271, 1996
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