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2O0F
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DOCKING OF THE MODIFIED RF3 X-RAY STRUCTURE INTO CRYO-EM MAP OF E.COLI 70S RIBOSOME BOUND WITH RF3
Descriptor:Peptide chain release factor 3
Authors:Gao, H., Zhou, Z., Rawat, U., Huang, C., Bouakaz, L., Wang, C., Liu, Y., Zavialov, A., Gursky, R., Sanyal, S., Ehrenberg, M., Frank, J., Song, H.
Deposit date:2006-11-27
Release date:2007-07-24
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (15.5 Å)
Cite:RF3 induces ribosomal conformational changes responsible for dissociation of class I release factors
Cell(Cambridge,Mass.), 129, 2007
2XEX
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CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS ELONGATION FACTOR G
Descriptor:ELONGATION FACTOR G, POTASSIUM ION, CHLORIDE ION
Authors:Chen, Y., Koripella, R.K., Sanyal, S., Selmer, M.
Deposit date:2010-05-19
Release date:2010-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Staphylococcus Aureus Elongation Factor G - Structure and Analysis of a Target for Fusidic Acid.
FEBS J., 277, 2010
3J9Z
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ACTIVATION OF GTP HYDROLYSIS IN MRNA-TRNA TRANSLOCATION BY ELONGATION FACTOR G
Descriptor:16S ribosomal RNA, P-tRNA, E-tRNA, ...
Authors:Li, W., Liu, Z., Koripella, R.K., Langlois, R., Sanyal, S., Frank, J.
Deposit date:2015-03-27
Release date:2015-07-01
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G.
Sci Adv, 1, 2015
3JA1
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ACTIVATION OF GTP HYDROLYSIS IN MRNA-TRNA TRANSLOCATION BY ELONGATION FACTOR G
Descriptor:30S ribosomal protein S19, 16S ribosomal RNA, mRNA, ...
Authors:Li, W., Liu, Z., Koripella, R.K., Langlois, R., Sanyal, S., Frank, J.
Deposit date:2015-03-30
Release date:2015-07-01
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G.
Sci Adv, 1, 2015
3ZZ0
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CRYSTAL STRUCTURE OF RIBOSOMAL ELONGATION FACTOR (EF)-G FROM STAPHYLOCOCCUS AUREUS WITH A FUSIDIC ACID HYPER-SENSITIVITY MUTATION M16I
Descriptor:Elongation factor G
Authors:Koripella, R.K., Chen, Y., Selmer, M., Sanyal, S.
Deposit date:2011-08-30
Release date:2012-07-18
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanism of elongation factor-G-mediated fusidic acid resistance and fitness compensation in Staphylococcus aureus.
J. Biol. Chem., 287, 2012
3ZZT
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CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS ELONGATION FACTOR G WITH A FUSIDIC-ACID-RESISTANT MUTATION F88L
Descriptor:ELONGATION FACTOR G
Authors:Koripella, R.K., Chen, Y., Selmer, M., Sanyal, S.
Deposit date:2011-09-05
Release date:2012-07-18
Last modified:2012-09-19
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Mechanism of Elongation Factor-G-Mediated Fusidic Acid Resistance and Fitness Compensation in Staphylococcus Aureus.
J.Biol.Chem., 287, 2012
3ZZU
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CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS ELONGATION FACTOR G WITH MUTATIONS M16I AND F88L
Descriptor:ELONGATION FACTOR G
Authors:Koripella, R.K., Chen, Y., Selmer, M., Sanyal, S.
Deposit date:2011-09-05
Release date:2012-07-18
Last modified:2012-09-19
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Mechanism of Elongation Factor-G Mediated Fusidic Acid Resistance and Fitness Compensation in Staphylococcus Aureus.
J.Biol.Chem., 287, 2012
4ADN
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FUSIDIC ACID RESISTANCE PROTEIN FUSB
Descriptor:FAR1, ZINC ION, SODIUM ION, ...
Authors:Guo, X., Peisker, K., Backbro, K., Chen, Y., Kiran, R.K., Sanyal, S., Selmer, M.
Deposit date:2011-12-31
Release date:2012-03-07
Last modified:2012-07-04
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure and Function of Fusb: An Elongation Factor G-Binding Fusidic Acid Resistance Protein Active in Ribosomal Translocation and Recycling
Open Biol., 2, 2012
4ADO
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FUSIDIC ACID RESISTANCE PROTEIN FUSB
Descriptor:FAR1, ZINC ION
Authors:Guo, X., Peisker, K., Backbro, K., Chen, Y., Kiran, R.K., Sanyal, S., Selmer, M.
Deposit date:2011-12-31
Release date:2012-03-07
Last modified:2012-07-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and Function of Fusb: An Elongation Factor G-Binding Fusidic Acid Resistance Protein Active in Ribosomal Translocation and Recycling
Open Biol., 2, 2012
4CSU
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CRYO-EM STRUCTURES OF THE 50S RIBOSOME SUBUNIT BOUND WITH OBGE
Descriptor:50S RIBOSOMAL PROTEIN L28, 50S RIBOSOMAL PROTEIN L29, 50S RIBOSOMAL PROTEIN L30, ...
Authors:Feng, B., Mandava, C.S., Guo, Q., Wang, J., Cao, W., Li, N., Zhang, Y., Zhang, Y., Wang, Z., Wu, J., Sanyal, S., Lei, J., Gao, N.
Deposit date:2014-03-10
Release date:2014-06-04
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (5.5 Å)
Cite:Structural and Functional Insights Into the Mode of Action of a Universally Conserved Obg Gtpase.
Plos Biol., 12, 2014
5ADY
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CRYO-EM STRUCTURES OF THE 50S RIBOSOME SUBUNIT BOUND WITH HFLX
Descriptor:50S RIBOSOMAL PROTEIN L32, 50S RIBOSOMAL PROTEIN L33, 50S RIBOSOMAL PROTEIN L34, ...
Authors:Zhang, Y., Mandava, C.S., Cao, W., Li, X., Zhang, D., Li, N., Zhang, Y., Zhang, X., Qin, Y., Mi, K., Lei, J., Sanyal, S., Gao, N.
Deposit date:2015-08-25
Release date:2015-10-14
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Hflx is a Ribosome Splitting Factor Rescuing Stalled Ribosomes Under Stress Conditions
Nat.Struct.Mol.Biol., 22, 2015
5XYM
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LARGE SUBUNIT OF MYCOBACTERIUM SMEGMATIS
Descriptor:50S ribosomal protein L32, 50S ribosomal protein L33 2, 50S ribosomal protein L34, ...
Authors:Li, Z., Ge, X., Zhang, Y., Zheng, L., Sanyal, S., Gao, N.
Deposit date:2017-07-09
Release date:2017-09-27
Last modified:2018-04-11
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Cryo-EM structure of Mycobacterium smegmatis ribosome reveals two unidentified ribosomal proteins close to the functional centers.
Protein Cell, 9, 2018
5XYU
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SMALL SUBUNIT OF MYCOBACTERIUM SMEGMATIS RIBOSOME
Descriptor:16S RNA, 30S ribosomal protein S3, 30S ribosomal protein S4, ...
Authors:Li, Z., Zhang, Y., Zheng, L., Ge, X., Sanyal, S., Gao, N.
Deposit date:2017-07-10
Release date:2017-09-27
Last modified:2018-04-11
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Cryo-EM structure of Mycobacterium smegmatis ribosome reveals two unidentified ribosomal proteins close to the functional centers.
Protein Cell, 9, 2018
2H5E
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CRYSTAL STRUCTURE OF E.COLI POLYPEPTIDE RELEASE FACTOR RF3
Descriptor:Peptide chain release factor RF-3, GUANOSINE-5'-DIPHOSPHATE
Authors:Song, H.W., Zhou, Z.H.
Deposit date:2006-05-26
Release date:2007-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:RF3 induces ribosomal conformational changes responsible for dissociation of class I release factors
Cell(Cambridge,Mass.), 129, 2007
3EP2
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MODEL OF PHE-TRNA(PHE) IN THE RIBOSOMAL PRE-ACCOMMODATED STATE REVEALED BY CRYO-EM
Descriptor:Elongation factor Tu, 30S ribosomal protein S12, 50S ribosomal protein L11, ...
Authors:Frank, J., Li, W., Agirrezabala, X.
Deposit date:2008-09-29
Release date:2008-12-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM.
Embo J., 27, 2008
3EQ3
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MODEL OF TRNA(TRP)-EF-TU IN THE RIBOSOMAL PRE-ACCOMMODATED STATE REVEALED BY CRYO-EM
Descriptor:Elongation factor Tu, 30S ribosomal protein S12, 50S ribosomal protein L11, ...
Authors:Frank, J., Li, W., Agirrezabala, X.
Deposit date:2008-09-30
Release date:2008-12-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM.
Embo J., 27, 2008
3EQ4
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MODEL OF TRNA(LEU)-EF-TU IN THE RIBOSOMAL PRE-ACCOMMODATED STATE REVEALED BY CRYO-EM
Descriptor:Elongation factor Tu, 30S ribosomal protein S12, 50S ribosomal protein L11, ...
Authors:Frank, J., Li, W., Agirrezabala, X.
Deposit date:2008-09-30
Release date:2008-12-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (12 Å)
Cite:Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM.
Embo J., 27, 2008
3RB9
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CRYSTAL STRUCTURE OF THE M. TUBERCULOSIS BETA CLAMP
Descriptor:DNA polymerase III subunit beta
Authors:Kukshal, V., Ramachandran, R.
Deposit date:2011-03-29
Release date:2012-04-04
Last modified:2013-02-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:M. tuberculosis Sliding beta-Clamp Does Not Interact Directly with the NAD(+)-Dependent DNA Ligase
Plos One, 7, 2012
5WDT
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70S RIBOSOME-EF-TU H84A COMPLEX WITH GPPNHP
Descriptor:23S rRNA, 5S rRNA, 50S ribosomal protein L2, ...
Authors:Fislage, M., Brown, Z., Frank, J.
Deposit date:2017-07-06
Release date:2018-04-25
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018
5WE4
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70S RIBOSOME-EF-TU WT COMPLEX WITH GPPNHP
Descriptor:23S rRNA, 5S rRNA, 50S ribosomal protein L2, ...
Authors:Fislage, M., Brown, Z., Frank, J.
Deposit date:2017-07-07
Release date:2018-04-25
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018
5WE6
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70S RIBOSOME-EF-TU H84A COMPLEX WITH GTP AND COGNATE TRNA
Descriptor:23S rRNA, 5S rRNA, 50S ribosomal protein L2, ...
Authors:Fislage, M., Frank, J.
Deposit date:2017-07-07
Release date:2018-04-25
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018
5WF0
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70S RIBOSOME-EF-TU H84A COMPLEX WITH GTP AND NEAR-COGNATE TRNA (COMPLEX C2)
Descriptor:23S rRNA, 5S rRNA, 50S ribosomal protein L2, ...
Authors:Fislage, M., Frank, J.
Deposit date:2017-07-11
Release date:2018-05-02
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018
5WFK
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70S RIBOSOME-EF-TU H84A COMPLEX WITH GTP AND NEAR-COGNATE TRNA (COMPLEX C3)
Descriptor:23S rRNA, 5S rRNA, 50S ribosomal protein L2, ...
Authors:Fislage, M., Frank, J.
Deposit date:2017-07-12
Release date:2018-05-02
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018
5WFS
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70S RIBOSOME-EF-TU H84A COMPLEX WITH GTP AND NEAR-COGNATE TRNA (COMPLEX C4)
Descriptor:23S rRNA, 5S rRNA, 50S ribosomal protein L2, ...
Authors:Fislage, M., Frank, J.
Deposit date:2017-07-12
Release date:2018-05-02
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018