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5YVV
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CRYSTAL STRUCTURE OF FULL LENGTH NS3 PROTEIN (GD4NS2BNS3) FROM DENV4 IN CLOSED CONFORMATION
Descriptor:Genome polyprotein
Authors:PHOO, W.W., Sahili, A.E.
Deposit date:2017-11-27
Release date:2018-12-05
Method:X-RAY DIFFRACTION (3.097 Å)
Cite:Crystal structures of unlinked full length NS3 from Dengue virus provide insights into dynamics of protease domain
To Be Published
5WRP
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T-STATE CRYSTAL STRUCTURE OF PYRUVATE KINASE FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:Pyruvate kinase, PHOSPHATE ION
Authors:Zhong, W., Cai, Q., El Sahili, A., Lescar, J., Dedon, P.C.
Deposit date:2016-12-02
Release date:2017-11-15
Last modified:2018-01-10
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Allosteric pyruvate kinase-based "logic gate" synergistically senses energy and sugar levels in Mycobacterium tuberculosis.
Nat Commun, 8, 2017
5WS8
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PYRUVATE KINASE (PYK) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH OXALATE
Descriptor:Pyruvate kinase, MAGNESIUM ION, OXALATE ION
Authors:Zhong, W., Cai, Q., El Sahili, A., Lescar, J., Dedon, P.C.
Deposit date:2016-12-06
Release date:2017-11-15
Last modified:2018-01-10
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Allosteric pyruvate kinase-based "logic gate" synergistically senses energy and sugar levels in Mycobacterium tuberculosis.
Nat Commun, 8, 2017
5WS9
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PYRUVATE KINASE (PYK) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH OXALATE, ATP AND ALLOSTERIC ACTIVATOR AMP
Descriptor:Pyruvate kinase, MAGNESIUM ION, OXALATE ION, ...
Authors:Zhong, W., Cai, Q., El Sahili, A., Lescar, J., Dedon, P.C.
Deposit date:2016-12-06
Release date:2017-11-15
Last modified:2018-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Allosteric pyruvate kinase-based "logic gate" synergistically senses energy and sugar levels in Mycobacterium tuberculosis.
Nat Commun, 8, 2017
5WSA
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PYRUVATE KINASE (PYK) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH OXALATE AND ALLOSTERIC ACTIVATOR GLUCOSE 6-PHOSPHATE
Descriptor:Pyruvate kinase, ALPHA-D-GLUCOSE-6-PHOSPHATE, MAGNESIUM ION, ...
Authors:Zhong, W., Cai, Q., El Sahili, A., Lescar, J., Dedon, P.C.
Deposit date:2016-12-06
Release date:2017-11-15
Last modified:2018-01-10
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Allosteric pyruvate kinase-based "logic gate" synergistically senses energy and sugar levels in Mycobacterium tuberculosis.
Nat Commun, 8, 2017
5WSB
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PYRUVATE KINASE (PYK) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH OXALATE, ALLOSTERIC ACTIVATORS AMP AND GLUCOSE 6-PHOSPHATE
Descriptor:Pyruvate kinase, ADENOSINE MONOPHOSPHATE, ALPHA-D-GLUCOSE-6-PHOSPHATE, ...
Authors:Zhong, W., Cai, Q., El Sahili, A., Lescar, J., Dedon, P.C.
Deposit date:2016-12-06
Release date:2017-11-15
Last modified:2018-01-10
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Allosteric pyruvate kinase-based "logic gate" synergistically senses energy and sugar levels in Mycobacterium tuberculosis.
Nat Commun, 8, 2017
5WSC
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CRYSTAL OF PYRUVATE KINASE (PYK) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH OXALATE, SOAKED WITH ALLOSTERIC ACTIVATORS AMP AND GLUCOSE 6-PHOSPHATE
Descriptor:Pyruvate kinase, ADENOSINE MONOPHOSPHATE, ALPHA-D-GLUCOSE-6-PHOSPHATE, ...
Authors:Zhong, W., Cai, Q., El Sahili, A., Lescar, J., Dedon, P.C.
Deposit date:2016-12-06
Release date:2017-11-15
Last modified:2018-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Allosteric pyruvate kinase-based "logic gate" synergistically senses energy and sugar levels in Mycobacterium tuberculosis.
Nat Commun, 8, 2017
5YVJ
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CRYSTAL STRUCTURE OF FULL LENGTH NS2B47-NS3 (GD4NS2BNS3) FROM DENGUE VIRUS 4 IN OPEN CONFORMATION
Descriptor:Genome polyprotein, GLYCEROL
Authors:Phoo, W.W., El Sahili, A.
Deposit date:2017-11-26
Release date:2018-11-28
Method:X-RAY DIFFRACTION (2.508 Å)
Cite:Crystal structures of unlinked full length NS3 from Dengue virus provide insights into dynamics of protease domain
To Be Published
5YVY
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CRYSTAL STRUCTURE OF UNLINKED FULL LENGTH NS3 PROTEIN (ED4NS2BNS3) FROM DENV4 IN CLOSED CONFORMATION
Descriptor:Genome polyprotein
Authors:PHOO, W.W., El Sahili, A.
Deposit date:2017-11-27
Release date:2018-11-28
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structures of unlinked full length NS3 from Dengue virus provide insights into dynamics of protease domain
To Be Published
5YW1
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CRYSTAL STRUCTURE OF FULL LENGTH NS3 PROTEIN (ED4NS2BNS3) IN COMPLEX WITH BOVINE PANCREATIC TRYPSIN INHIBITOR
Descriptor:Peptidase S7, FLAVIVIRUS_NS2B, PTI protein
Authors:Phoo, W.W., El Sahili, A.
Deposit date:2017-11-28
Release date:2019-01-02
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of unlinked full length NS3 from Dengue virus provide insights into dynamics of protease domain
To Be Published
6AFK
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CRYSTAL STRUCTURE OF TRMD FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH ACTIVE-SITE INHIBITOR
Descriptor:tRNA (guanine-N(1)-)-methyltransferase, S-ADENOSYLMETHIONINE, N-{(3S)-1-[3-(pyridin-4-yl)-1H-pyrazol-5-yl]piperidin-3-yl}-1H-indole-2-carboxamide
Authors:Zhong, W., Koay, A., Wong, Y.W., Sahili, A.E., Nah, Q., Kang, C., Poulsen, A., Chionh, Y.K., McBee, M., Matter, A., Hill, J., Lescar, J., Dedon, P.C.
Deposit date:2018-08-08
Release date:2019-08-14
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal structure of TrmD from Pseudomonas aeruginosa in complex with active-site inhibitor
To Be Published