Author results

6C3F
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AMYLOID FORMING PEPTIDE IYKVEI FROM TRANSTHYRETIN
Descriptor:ILE-TYR-LYS-VAL-GLU-ILE, trifluoroacetic acid
Authors:Saelices, L., Sawaya, M.R., Eisenberg, D.S.
Deposit date:2018-01-09
Release date:2018-04-18
Last modified:2018-08-01
Method:X-RAY DIFFRACTION (1.499 Å)
Cite:Crystal structures of amyloidogenic segments of human transthyretin.
Protein Sci., 27, 2018
6C3G
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AMYLOID FORMING PEPTIDE KALGIS FROM TRANSTHYRETIN
Descriptor:LYS-ALA-LEU-GLY-ILE-SER, SULFATE ION, GLYCEROL
Authors:Saelices, L., Sawaya, M.R., Eisenberg, D.S.
Deposit date:2018-01-09
Release date:2018-04-18
Last modified:2018-08-01
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Crystal structures of amyloidogenic segments of human transthyretin.
Protein Sci., 27, 2018
6C88
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STRUCTURE OF THE AMYLOID FORMING PEPTIDE VAVHVF FROM TRANSTHYRETIN
Descriptor:VAL-ALA-VAL-HIS-VAL-PHE, GLYCEROL
Authors:Saelices, L., Sawaya, M.R., Eisenberg, D.S.
Deposit date:2018-01-24
Release date:2018-04-18
Last modified:2018-08-01
Method:X-RAY DIFFRACTION (1.851 Å)
Cite:Crystal structures of amyloidogenic segments of human transthyretin.
Protein Sci., 27, 2018
4TKW
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN LEU55PRO MUTANT
Descriptor:Transthyretin
Authors:Saelices, L., Cascio, D., Sawaya, M., Eisenberg, D.S.
Deposit date:2014-05-27
Release date:2015-10-21
Last modified:2016-12-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TL4
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN VAL30MET MUTANT
Descriptor:Transthyretin
Authors:Saelices, L., Cascio, D., Sawaya, M., Eisenberg, D.S.
Deposit date:2014-05-28
Release date:2015-10-21
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TL5
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN SER85PRO MUTANT
Descriptor:Transthyretin, SODIUM ION, CHLORIDE ION
Authors:Saelices, L., Cascio, D., Sawaya, M., Eisenberg, D.S.
Deposit date:2014-05-28
Release date:2015-10-21
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TLK
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN SER85PRO/GLU92PRO MUTANT
Descriptor:Transthyretin, SODIUM ION, GLYCEROL, ...
Authors:Saelices, L., Cascio, D., Sawaya, M., Eisenberg, D.S.
Deposit date:2014-05-30
Release date:2015-10-21
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TLS
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN GLU92PRO MUTANT
Descriptor:Transthyretin, PHOSPHATE ION, GLYCEROL, ...
Authors:Saelices, L., Cascio, D., Sawaya, M., Eisenberg, D.S.
Deposit date:2014-05-30
Release date:2015-10-21
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TLT
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN
Descriptor:Transthyretin, MAGNESIUM ION
Authors:Saelices, L., Cascio, D., Sawaya, M., Eisenberg, D.S.
Deposit date:2014-05-30
Release date:2015-10-21
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TM9
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN THR119TRP MUTANT
Descriptor:Transthyretin
Authors:Saelices, L., Cascio, D., Sawaya, M., Eisenberg, D.S.
Deposit date:2014-05-31
Release date:2015-10-21
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TNE
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN THR119TYR MUTANT
Descriptor:Transthyretin, GLYCEROL
Authors:Saelices, L., Cascio, D., Sawaya, M., Eisenberg, D.S.
Deposit date:2014-06-03
Release date:2015-10-21
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4XFN
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STRUCTURE OF AN AMYLOID FORMING PEPTIDE AEVVFT FROM HUMAN TRANSTHYRETIN
Descriptor:Amyloid forming peptide AEVVFT
Authors:Saelices, L., Sawaya, M., Cascio, D., Eisenberg, D.S.
Deposit date:2014-12-27
Release date:2015-10-21
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4XFO
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STRUCTURE OF AN AMYLOID-FORMING SEGMENT TAVVTN FROM HUMAN TRANSTHYRETIN
Descriptor:Amyloid-forming peptide TAVVTN
Authors:Saelices, L., Sawaya, M., Cascio, D., Eisenberg, D.S.
Deposit date:2014-12-27
Release date:2015-10-21
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
3NG0
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CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SYNECHOCYSTIS SP. PCC 6803
Descriptor:Glutamine synthetase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MANGANESE (II) ION
Authors:Saelices, L., Cascio, D., Florencio, F.J., Muro-Pastor, M.I.
Deposit date:2010-06-10
Release date:2011-06-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of Glutamine Synthetase from Synechocystis sp. PCC 6803
To be Published
4TLU
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN ALA108TRP MUTANT
Descriptor:Transthyretin, CHLORIDE ION
Authors:Saelices, L., Cascio, D., Sawaya, M., Eisenberg, D.S.
Deposit date:2014-05-30
Release date:2015-12-30
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal Structure of Human Transthyretin Ala108Trp Mutant
to be published
4TNF
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN LYS15TRP MUTANT
Descriptor:Transthyretin
Authors:Saelices, L., Cascio, D., Sawaya, M., Eisenberg, D.S.
Deposit date:2014-06-03
Release date:2015-12-30
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structure of Human Transthyretin Lys15Trp Mutant
to be published
4TNG
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN THR119MET MUTANT
Descriptor:Transthyretin
Authors:Saelices, L., Cascio, D., Sawaya, M., Eisenberg, D.S.
Deposit date:2014-06-04
Release date:2015-12-30
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structure of Human Transthyretin Thr119Met Mutant
to be published
6C3S
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AMYLOID FORMING PEPTIDE YTIAAL FROM TRANSTHYRETIN
Descriptor:TYR-THR-ILE-ALA-ALA-LEU
Authors:Sievers, S.A., Sawaya, M.R., Saelices, L., Eisenberg, D.S.
Deposit date:2018-01-10
Release date:2018-04-18
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (1.602 Å)
Cite:Crystal structures of amyloidogenic segments of human transthyretin.
Protein Sci., 27, 2018
6C3T
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AMYLOID FORMING PEPTIDE AADTWE FROM TRANSTHYRETIN WITH ATTR-D38A MUTATION ASSOCIATED WITH A FAMILIAL FORM OF TRANSTHYRETIN AMYLOIDOSIS
Descriptor:ALA-ALA-ASP-THR-TRP-GLU
Authors:Sievers, S.A., Sawaya, M.R., Saelices, L., Eisenberg, D.S.
Deposit date:2018-01-10
Release date:2018-04-18
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (1 Å)
Cite:Crystal structures of amyloidogenic segments of human transthyretin.
Protein Sci., 27, 2018
6C4O
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AMYLOID FORMING PEPTIDE TIAALLS FROM TRANSTHYRETIN
Descriptor:THR-ILE-ALA-ALA-LEU-LEU-SER
Authors:Sievers, S.A., Sawaya, M.R., Saelices, L., Eisenberg, D.S.
Deposit date:2018-01-12
Release date:2018-04-18
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Crystal structures of amyloidogenic segments of human transthyretin.
Protein Sci., 27, 2018
5VOS
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VGSNKGAIIGL FROM AMYLOID BETA DETERMINED BY MICROED
Descriptor:Amyloid beta A4 protein
Authors:Rodriguez, J.A., Sawaya, M.R., Cascio, D., Eisenberg, D.S., Griner, S.L., Gonen, T.
Deposit date:2017-05-03
Release date:2018-01-03
Last modified:2018-06-06
Method:ELECTRON CRYSTALLOGRAPHY (1.42 Å)
Cite:Common fibrillar spines of amyloid-beta and human islet amyloid polypeptide revealed by microelectron diffraction and structure-based inhibitors.
J. Biol. Chem., 293, 2018