Author results

4U6Q
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CTBP1 BOUND TO INHIBITOR 2-(HYDROXYIMINO)-3-PHENYLPROPANOIC ACID
Descriptor:C-terminal-binding protein 1, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, (2E)-2-(hydroxyimino)-3-phenylpropanoic acid, ...
Authors:Hilbert, B.J., Morris, B.L., Ellis, K.C., Paulsen, J.L., Schiffer, C.A., Grossman, S.R., Royer Jr., W.E.
Deposit date:2014-07-29
Release date:2015-02-11
Last modified:2015-04-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-Guided Design of a High Affinity Inhibitor to Human CtBP.
Acs Chem.Biol., 10, 2015
4U6S
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CTBP1 IN COMPLEX WITH SUBSTRATE PHENYLPYRUVATE
Descriptor:C-terminal-binding protein 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 3-PHENYLPYRUVIC ACID, ...
Authors:Hilbert, B.J., Morris, B.L., Ellis, K.C., Paulsen, J.L., Schiffer, C.A., Grossman, S.R., Royer Jr., W.E.
Deposit date:2014-07-29
Release date:2015-02-11
Last modified:2015-04-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-Guided Design of a High Affinity Inhibitor to Human CtBP.
Acs Chem.Biol., 10, 2015
4LCE
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CTBP1 IN COMPLEX WITH SUBSTRATE MTOB
Descriptor:C-terminal-binding protein 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 4-(METHYLSULFANYL)-2-OXOBUTANOIC ACID
Authors:Hilbert, B.J., Schiffer, C.A., Royer Jr., W.E.
Deposit date:2013-06-21
Release date:2014-03-19
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Crystal structures of human CtBP in complex with substrate MTOB reveal active site features useful for inhibitor design.
Febs Lett., 588, 2014
4LCJ
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CTBP2 IN COMPLEX WITH SUBSTRATE MTOB
Descriptor:C-terminal-binding protein 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 4-(METHYLSULFANYL)-2-OXOBUTANOIC ACID
Authors:Hilbert, B.J., Schiffer, C.A., Royer Jr., W.E.
Deposit date:2013-06-21
Release date:2014-03-19
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Crystal structures of human CtBP in complex with substrate MTOB reveal active site features useful for inhibitor design.
Febs Lett., 588, 2014
3UGY
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HBI (F80Y) CO BOUND
Descriptor:Globin-1, PROTOPORPHYRIN IX CONTAINING FE, CARBON MONOXIDE
Authors:Ren, Z., Srajer, V., Knapp, J.E., Royer Jr., W.E.
Deposit date:2011-11-03
Release date:2011-12-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures.
Proc.Natl.Acad.Sci.USA, 109, 2012
3UGZ
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HBI (L36A) CO BOUND
Descriptor:Globin-1, PROTOPORPHYRIN IX CONTAINING FE, CARBON MONOXIDE
Authors:Ren, Z., Srajer, V., Knapp, J.E., Royer Jr., W.E.
Deposit date:2011-11-03
Release date:2011-12-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures.
Proc.Natl.Acad.Sci.USA, 109, 2012
3UH3
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HBI (L36V) CO BOUND
Descriptor:Globin-1, PROTOPORPHYRIN IX CONTAINING FE, CARBON MONOXIDE
Authors:Ren, Z., Srajer, V., Knapp, J.E., Royer Jr., W.E.
Deposit date:2011-11-03
Release date:2011-12-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures.
Proc.Natl.Acad.Sci.USA, 109, 2012
3UH5
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HBI (L36F) CO BOUND
Descriptor:Globin-1, PROTOPORPHYRIN IX CONTAINING FE, CARBON MONOXIDE
Authors:Ren, Z., Srajer, V., Knapp, J.E., Royer Jr., W.E.
Deposit date:2011-11-03
Release date:2011-12-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures.
Proc.Natl.Acad.Sci.USA, 109, 2012
3UH6
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HBI (T72A) CO BOUND
Descriptor:Globin-1, PROTOPORPHYRIN IX CONTAINING FE, CARBON MONOXIDE
Authors:Ren, Z., Srajer, V., Knapp, J.E., Royer Jr., W.E.
Deposit date:2011-11-03
Release date:2011-12-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures.
Proc.Natl.Acad.Sci.USA, 109, 2012
3UH7
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HBI (T72G) CO BOUND
Descriptor:Globin-1, PROTOPORPHYRIN IX CONTAINING FE, CARBON MONOXIDE
Authors:Ren, Z., Srajer, V., Knapp, J.E., Royer Jr., W.E.
Deposit date:2011-11-03
Release date:2011-12-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures.
Proc.Natl.Acad.Sci.USA, 109, 2012
3UHB
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HBI (R104K) CO BOUND
Descriptor:Globin-1, PROTOPORPHYRIN IX CONTAINING FE, CARBON MONOXIDE
Authors:Ren, Z., Srajer, V., Knapp, J.E., Royer Jr., W.E.
Deposit date:2011-11-03
Release date:2011-12-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures.
Proc.Natl.Acad.Sci.USA, 109, 2012
3UHC
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HBI (N79A) CO BOUND
Descriptor:Globin-1, PROTOPORPHYRIN IX CONTAINING FE, CARBON MONOXIDE
Authors:Ren, Z., Srajer, V., Knapp, J.E., Royer Jr., W.E.
Deposit date:2011-11-03
Release date:2011-12-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures.
Proc.Natl.Acad.Sci.USA, 109, 2012
3UHD
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HBI (N100A) CO BOUND
Descriptor:Globin-1, PROTOPORPHYRIN IX CONTAINING FE, CARBON MONOXIDE
Authors:Ren, Z., Srajer, V., Knapp, J.E., Royer Jr., W.E.
Deposit date:2011-11-03
Release date:2011-12-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures.
Proc.Natl.Acad.Sci.USA, 109, 2012
3UHE
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HBI (M37V,L73I) CO BOUND
Descriptor:Globin-1, PROTOPORPHYRIN IX CONTAINING FE, CARBON MONOXIDE
Authors:Ren, Z., Srajer, V., Knapp, J.E., Royer Jr., W.E.
Deposit date:2011-11-03
Release date:2011-12-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures.
Proc.Natl.Acad.Sci.USA, 109, 2012
3UHG
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HBI (L36M) CO BOUND
Descriptor:Globin-1, PROTOPORPHYRIN IX CONTAINING FE, CARBON MONOXIDE
Authors:Ren, Z., Srajer, V., Knapp, J.E., Royer Jr., W.E.
Deposit date:2011-11-03
Release date:2011-12-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures.
Proc.Natl.Acad.Sci.USA, 109, 2012
3UHH
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HBI (M37A) CO BOUND
Descriptor:Globin-1, PROTOPORPHYRIN IX CONTAINING FE, CARBON MONOXIDE
Authors:Ren, Z., Srajer, V., Knapp, J.E., Royer Jr., W.E.
Deposit date:2011-11-03
Release date:2011-12-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures.
Proc.Natl.Acad.Sci.USA, 109, 2012
3UHI
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HBI (K96R) CO BOUND
Descriptor:Globin-1, PROTOPORPHYRIN IX CONTAINING FE, CARBON MONOXIDE
Authors:Ren, Z., Srajer, V., Knapp, J.E., Royer Jr., W.E.
Deposit date:2011-11-03
Release date:2011-12-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures.
Proc.Natl.Acad.Sci.USA, 109, 2012
3UHK
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HBI (K96R) WITHOUT LIGAND BOUND
Descriptor:Globin-1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Ren, Z., Srajer, V., Knapp, J.E., Royer Jr., W.E.
Deposit date:2011-11-03
Release date:2011-12-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures.
Proc.Natl.Acad.Sci.USA, 109, 2012
3UHN
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HBI (F80Y) DEOXY
Descriptor:Globin-1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Ren, Z., Srajer, V., Knapp, J.E., Royer Jr., W.E.
Deposit date:2011-11-03
Release date:2011-12-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures.
Proc.Natl.Acad.Sci.USA, 109, 2012
3UHQ
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HBI (L36A) DEOXY
Descriptor:Globin-1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Ren, Z., Srajer, V., Knapp, J.E., Royer Jr., W.E.
Deposit date:2011-11-03
Release date:2011-12-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures.
Proc.Natl.Acad.Sci.USA, 109, 2012
3UHR
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HBI (L36F) DEOXY
Descriptor:Globin-1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Ren, Z., Srajer, V., Knapp, J.E., Royer Jr., W.E.
Deposit date:2011-11-03
Release date:2011-12-28
Last modified:2012-01-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures.
Proc.Natl.Acad.Sci.USA, 109, 2012
3UHS
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HBI (L36M) DEOXY
Descriptor:Globin-1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Ren, Z., Srajer, V., Knapp, J.E., Royer Jr., W.E.
Deposit date:2011-11-03
Release date:2011-12-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures.
Proc.Natl.Acad.Sci.USA, 109, 2012
3UHT
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HBI (L36V) DEOXY
Descriptor:Globin-1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Ren, Z., Srajer, V., Knapp, J.E., Royer Jr., W.E.
Deposit date:2011-11-03
Release date:2011-12-28
Last modified:2012-01-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures.
Proc.Natl.Acad.Sci.USA, 109, 2012
3UHU
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HBI (M37A) DEOXY
Descriptor:Globin-1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Ren, Z., Srajer, V., Knapp, J.E., Royer Jr., W.E.
Deposit date:2011-11-03
Release date:2011-12-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures.
Proc.Natl.Acad.Sci.USA, 109, 2012
3UHV
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HBI (M37V,L73I) DEOXY
Descriptor:Globin-1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Ren, Z., Srajer, V., Knapp, J.E., Royer Jr., W.E.
Deposit date:2011-11-03
Release date:2011-12-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures.
Proc.Natl.Acad.Sci.USA, 109, 2012