Ligand Migration and Binding in The Dimeric Hemoglobin of Scapharca Inaequivalvis: Structure of I25W with CO

Summary for 2R4Z

Related3SDH 4SDH 2GRH 2Z85 2Z8A 2R4W 2R4X 2R4Y
DescriptorGlobin-1, PHOSPHATE ION, PROTOPORPHYRIN IX CONTAINING FE, ... (5 entities in total)
Functional Keywordsoxygen transport, allostery, oxygen affinity, oxygen storage/transport, cytoplasm, heme, iron, metal-binding, oxygen binding
Biological sourceScapharca inaequivalvis (ark clam)
Cellular locationCytoplasm P02213
Total number of polymer chains2
Total molecular weight33464.68
Knapp, J.E.,Royer Jr., W.E.,Nienhaus, K.,Palladino, P.,Nienhaus, G.U. (deposition date: 2007-09-02, release date: 2007-11-27, Last modification date: 2017-10-25)
Primary citation
Nienhaus, K.,Knapp, J.E.,Palladino, P.,Royer Jr., W.E.,Nienhaus, G.U.
Ligand Migration and Binding in the Dimeric Hemoglobin of Scapharca inaequivalvis
Biochemistry, 46:14018-14031, 2007
PubMed: 18001141 (PDB entries with the same primary citation)
DOI: 10.1021/bi7016798
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.223501.3%0.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2r4z
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Molmil generated image of 2r4z
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Molmil generated image of 2r4z
rotated about y axis by 90°