Ligand Migration and Binding in The Dimeric Hemoglobin of Scapharca Inaequivalvis: I25W with CO Bound to HEME and in the Presence of 3 Atoms of XE

Summary for 2Z8A

Related3SDH 4SDH 2GRH 2Z85 2R4W 2R4X 2R4Y 2R4Z
DescriptorGlobin-1, PROTOPORPHYRIN IX CONTAINING FE, CARBON MONOXIDE, ... (6 entities in total)
Functional Keywordsoxygen transport, allostery, oxygen affinity, cytoplasm, heme, iron, metal-binding, oxygen storage/transport, oxygen binding
Biological sourceScapharca inaequivalvis (ark clam)
Cellular locationCytoplasm P02213
Total number of polymer chains2
Total molecular weight33989.85
Knapp, J.E.,Royer Jr., W.E.,Nienhaus, K.,Palladino, P.,Nienhaus, G.U. (deposition date: 2007-09-04, release date: 2007-11-27, Last modification date: 2017-10-11)
Primary citation
Nienhaus, K.,Knapp, J.E.,Palladino, P.,Royer Jr., W.E.,Nienhaus, G.U.
Ligand Migration and Binding in the Dimeric Hemoglobin of Scapharca inaequivalvis
Biochemistry, 46:14018-14031, 2007
PubMed: 18001141 (PDB entries with the same primary citation)
DOI: 10.1021/bi7016798
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.166300.9%1.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2z8a
no rotation
Molmil generated image of 2z8a
rotated about x axis by 90°
Molmil generated image of 2z8a
rotated about y axis by 90°