Author results

1HSM
  • Download 1hsm
  • View 1hsm
Molmil generated image of 1hsm
THE STRUCTURE OF THE HMG BOX AND ITS INTERACTION WITH DNA
Descriptor:HIGH MOBILITY GROUP PROTEIN 1, BETA-MERCAPTOETHANOL
Authors:Read, C.M., Cary, P.D., Crane-Robinson, C., Driscoll, P.C., Carillo, M.O.M., Norman, D.G.
Deposit date:1994-11-17
Release date:1995-02-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The Structure of the Hmg Box and its Interaction with DNA
To be Published
1HSN
  • Download 1hsn
  • View 1hsn
Molmil generated image of 1hsn
THE STRUCTURE OF THE HMG BOX AND ITS INTERACTION WITH DNA
Descriptor:HIGH MOBILITY GROUP PROTEIN 1, BETA-MERCAPTOETHANOL
Authors:Read, C.M., Cary, P.D., Crane-Robinson, C., Driscoll, P.C., Carillo, M.O.M., Norman, D.G.
Deposit date:1994-11-17
Release date:1995-02-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The Structure of the Hmg Box and its Interaction with DNA
To be Published
1NHM
  • Download 1nhm
  • View 1nhm
Molmil generated image of 1nhm
THE STRUCTURE OF THE HMG BOX AND ITS INTERACTION WITH DNA
Descriptor:HIGH MOBILITY GROUP PROTEIN 1
Authors:Read, C.M., Cary, P.D., Crane-Robinson, C., Driscoll, P.C., Carillo, M.O.M., Norman, D.G.
Deposit date:1994-11-17
Release date:1995-02-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The Structure of the Hmg Box and its Interaction with DNA
NUCLEIC ACIDS MOL.BIOL., 9, 1995
1NHN
  • Download 1nhn
  • View 1nhn
Molmil generated image of 1nhn
THE STRUCTURE OF THE HMG BOX AND ITS INTERACTION WITH DNA
Descriptor:HIGH MOBILITY GROUP PROTEIN 1
Authors:Read, C.M., Cary, P.D., Crane-Robinson, C., Driscoll, P.C., Carillo, M.O.M., Norman, D.G.
Deposit date:1994-11-17
Release date:1995-02-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The Structure of the Hmg Box and its Interaction with DNA
NUCLEIC ACIDS MOL.BIOL., 9, 1995
1V92
  • Download 1v92
  • View 1v92
Molmil generated image of 1v92
SOLUTION STRUCTURE OF THE UBA DOMAIN FROM P47, A MAJOR COFACTOR OF THE AAA ATPASE P97
Descriptor:NSFL1 cofactor p47
Authors:Yuan, X., Simpson, P., Mckeown, C., Kondo, H., Uchiyama, K., Wallis, R., Dreveny, I., Keetch, C., Zhang, X., Robinson, C., Freemont, P., Matthews, S.
Deposit date:2004-01-19
Release date:2004-04-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure, dynamics and interactions of p47, a major adaptor of the AAA ATPase, p97
Embo J., 23, 2004
1VAZ
  • Download 1vaz
  • View 1vaz
Molmil generated image of 1vaz
SOLUTION STRUCTURES OF THE P47 SEP DOMAIN
Descriptor:NSFL1 cofactor p47
Authors:Yuan, X., Simpson, P., Mckeown, C., Kondo, H., Uchiyama, K., Wallis, R., Dreveny, I., Keetch, C., Zhang, X., Robinson, C., Freemont, P., Matthews, S.
Deposit date:2004-02-20
Release date:2004-04-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure, dynamics and interactions of p47, a major adaptor of the AAA ATPase, p97.
Embo J., 23, 2004
2VRD
  • Download 2vrd
  • View 2vrd
Molmil generated image of 2vrd
THE STRUCTURE OF THE ZINC FINGER FROM THE HUMAN SPLICEOSOMAL PROTEIN U1C
Descriptor:U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C, ZINC ION
Authors:Muto, Y., Pomeranz-Krummel, D., Oubridge, C., Hernandez, H., Robinson, C., Neuhaus, D., Nagai, K.
Deposit date:2008-03-31
Release date:2008-04-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The Structure and Biochemical Properties of the Human Spliceosomal Protein U1C
J.Mol.Biol., 341, 2004
1I11
  • Download 1i11
  • View 1i11
Molmil generated image of 1i11
SOLUTION STRUCTURE OF THE DNA BINDING DOMAIN, SOX-5 HMG BOX FROM MOUSE
Descriptor:TRANSCRIPTION FACTOR SOX-5
Authors:Cary, P.D., Read, C.M., Davis, B., Driscoll, P.C., Crane-Robinson, C.
Deposit date:2001-01-30
Release date:2001-02-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure and backbone dynamics of the DNA-binding domain of mouse Sox-5.
Protein Sci., 10, 2001
6OQR
  • Download 6oqr
  • View 6oqr
Molmil generated image of 6oqr
E. COLI ATP SYNTHASE ADP STATE 1A
Descriptor:ATP synthase subunit delta, ATP synthase subunit alpha, ATP synthase subunit b, ...
Authors:Stewart, A.G., Walshe, J.L., Sobti, M.
Deposit date:2019-04-29
Release date:2020-06-03
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structures provide insight into how E. coli F1Fo ATP synthase accommodates symmetry mismatch
Nat Commun, 2020
6OQS
  • Download 6oqs
  • View 6oqs
Molmil generated image of 6oqs
E. COLI ATP SYNTHASE STATE 1B
Descriptor:ATP synthase subunit delta, ATP synthase subunit alpha, ATP synthase subunit b, ...
Authors:Stewart, A.G., Sobti, M., Walshe, J.W.
Deposit date:2019-04-29
Release date:2020-06-03
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structures provide insight into how E. coli F1Fo ATP synthase accommodates symmetry mismatch
Nat Commun, 2020
6OQT
  • Download 6oqt
  • View 6oqt
Molmil generated image of 6oqt
E. COLI ATP SYNTHASE STATE 1C
Descriptor:ATP synthase subunit delta, ATP synthase subunit alpha, ATP synthase subunit b, ...
Authors:Stewart, A.G., Sobti, M., Walshe, J.W.
Deposit date:2019-04-29
Release date:2020-06-03
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structures provide insight into how E. coli F1Fo ATP synthase accommodates symmetry mismatch
Nat Commun, 2020
6OQU
  • Download 6oqu
  • View 6oqu
Molmil generated image of 6oqu
E. COLI ATP SYNTHASE STATE 1D
Descriptor:ATP synthase subunit delta, ATP synthase subunit alpha, ATP synthase subunit b, ...
Authors:Stewart, A.G., Sobti, M., Walshe, J.W.
Deposit date:2019-04-29
Release date:2020-06-03
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structures provide insight into how E. coli F1Fo ATP synthase accommodates symmetry mismatch
Nat Commun, 2020
6OQV
  • Download 6oqv
  • View 6oqv
Molmil generated image of 6oqv
E. COLI ATP SYNTHASE STATE 2B
Descriptor:ATP synthase subunit delta, ATP synthase subunit alpha, ATP synthase subunit b, ...
Authors:Stewart, G.A., Sobti, M., Walshe, J.L.
Deposit date:2019-04-29
Release date:2020-06-03
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structures provide insight into how E. coli F1Fo ATP synthase accommodates symmetry mismatch
Nat Commun, 2020
6PQV
  • Download 6pqv
  • View 6pqv
Molmil generated image of 6pqv
E. COLI ATP SYNTHASE STATE 1E
Descriptor:ATP synthase subunit delta, ATP synthase subunit alpha, ATP synthase subunit b, ...
Authors:Stewart, G.A., Sobti, M., Walshe, J.L.
Deposit date:2019-07-10
Release date:2020-06-03
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structures provide insight into how E. coli F1Fo ATP synthase accommodates symmetry mismatch
Nat Commun, 2020
6VWK
  • Download 6vwk
  • View 6vwk
Molmil generated image of 6vwk
E. COLI ATP SYNTHASE ADP SUB-STATE 3A FO FOCUSSED
Descriptor:ATP synthase subunit c, ATP synthase subunit b, ATP synthase subunit a
Authors:Stewart, A.G., Walshe, J.L., Sobti, M.
Deposit date:2020-02-20
Release date:2020-06-03
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM structures provide insight into how E. coli F1Fo ATP synthase accommodates symmetry mismatch
Nat Commun, 2020
6WNQ
  • Download 6wnq
  • View 6wnq
Molmil generated image of 6wnq
E. COLI ATP SYNTHASE STATE 2A
Descriptor:ATP synthase subunit delta, ATP synthase subunit alpha, ATP synthase subunit b, ...
Authors:Stewart, G.A., Sobti, M., Walshe, J.L.
Deposit date:2020-04-23
Release date:2020-06-03
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structures provide insight into how E. coli F1Fo ATP synthase accommodates symmetry mismatch
Nat Commun, 2020
6WNR
  • Download 6wnr
  • View 6wnr
Molmil generated image of 6wnr
E. COLI ATP SYNTHASE STATE 3B
Descriptor:ATP synthase subunit delta, ATP synthase subunit alpha, ATP synthase subunit b, ...
Authors:Stewart, A.G., Sobti, M., Walshe, J.W.
Deposit date:2020-04-23
Release date:2020-06-03
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structures provide insight into how E. coli F1Fo ATP synthase accommodates symmetry mismatch
Nat Commun, 2020
4M0Y
  • Download 4m0y
  • View 4m0y
Molmil generated image of 4m0y
CRYSTAL STRUCTURE OF ITK IN COMPLEX WITH COMPOUND 1 [4-(CARBAMOYLAMINO)-1-(NAPHTHALEN-1-YL)-1H-PYRAZOLE-3-CARBOXAMIDE]
Descriptor:Tyrosine-protein kinase ITK/TSK, 4-(carbamoylamino)-1-(naphthalen-1-yl)-1H-pyrazole-3-carboxamide
Authors:Han, S., Caspers, N.L.
Deposit date:2013-08-02
Release date:2014-04-02
Last modified:2014-06-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Selectively targeting an inactive conformation of interleukin-2-inducible T-cell kinase by allosteric inhibitors.
Biochem.J., 460, 2014
4M0Z
  • Download 4m0z
  • View 4m0z
Molmil generated image of 4m0z
CRYSTAL STRUCTURE OF ITK IN COMPLEX WITH COMPOUND 5 {4-(CARBAMOYLAMINO)-1-(7-METHOXYNAPHTHALEN-1-YL)-1H-PYRAZOLE-3-CARBOXAMIDE}
Descriptor:Tyrosine-protein kinase ITK/TSK, 4-(carbamoylamino)-1-(7-methoxynaphthalen-1-yl)-1H-pyrazole-3-carboxamide
Authors:Han, S., Caspers, N.L.
Deposit date:2013-08-02
Release date:2014-04-02
Last modified:2014-06-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Selectively targeting an inactive conformation of interleukin-2-inducible T-cell kinase by allosteric inhibitors.
Biochem.J., 460, 2014
4M12
  • Download 4m12
  • View 4m12
Molmil generated image of 4m12
CRYSTAL STRUCTURE OF ITK IN COMPLEX WITH COMPOUND 7 [4-(CARBAMOYLAMINO)-1-(7-ETHOXYNAPHTHALEN-1-YL)-1H-PYRAZOLE-3-CARBOXAMIDE]
Descriptor:Tyrosine-protein kinase ITK/TSK, 4-(carbamoylamino)-1-(7-ethoxynaphthalen-1-yl)-1H-pyrazole-3-carboxamide
Authors:Han, S., Caspers, N.L.
Deposit date:2013-08-02
Release date:2014-04-02
Last modified:2014-06-04
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Selectively targeting an inactive conformation of interleukin-2-inducible T-cell kinase by allosteric inhibitors.
Biochem.J., 460, 2014
4M13
  • Download 4m13
  • View 4m13
Molmil generated image of 4m13
CRYSTAL STRUCTURE OF ITK IN COMPLEX WITH COMPOUND 8 [4-(CARBAMOYLAMINO)-1-(7-PROPOXYNAPHTHALEN-1-YL)-1H-PYRAZOLE-3-CARBOXAMIDE]
Descriptor:Tyrosine-protein kinase ITK/TSK, 4-(carbamoylamino)-1-(7-propoxynaphthalen-1-yl)-1H-pyrazole-3-carboxamide
Authors:Han, S., Caspers, N.L.
Deposit date:2013-08-02
Release date:2014-04-02
Last modified:2014-06-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Selectively targeting an inactive conformation of interleukin-2-inducible T-cell kinase by allosteric inhibitors.
Biochem.J., 460, 2014
4M14
  • Download 4m14
  • View 4m14
Molmil generated image of 4m14
CRYSTAL STRUCTURE OF ITK IN COMPLEX WITH COMPOUND 9 [4-(CARBAMOYLAMINO)-1-[7-(PROPAN-2-YLOXY)NAPHTHALEN-1-YL]-1H-PYRAZOLE-3-CARBOXAMIDE]
Descriptor:Tyrosine-protein kinase ITK/TSK, 4-(carbamoylamino)-1-[7-(propan-2-yloxy)naphthalen-1-yl]-1H-pyrazole-3-carboxamide
Authors:Han, S., Caspers, N.L.
Deposit date:2013-08-02
Release date:2014-04-02
Last modified:2014-06-04
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Selectively targeting an inactive conformation of interleukin-2-inducible T-cell kinase by allosteric inhibitors.
Biochem.J., 460, 2014
4M15
  • Download 4m15
  • View 4m15
Molmil generated image of 4m15
CRYSTAL STRUCTURE OF ITK IN COMPLEX WITH COMPOUND 9 [4-(CARBAMOYLAMINO)-1-[7-(PROPAN-2-YLOXY)NAPHTHALEN-1-YL]-1H-PYRAZOLE-3-CARBOXAMIDE] AND ADP
Descriptor:Tyrosine-protein kinase ITK/TSK, 4-(carbamoylamino)-1-[7-(propan-2-yloxy)naphthalen-1-yl]-1H-pyrazole-3-carboxamide, ADENOSINE-5'-DIPHOSPHATE
Authors:Han, S., Caspers, N.L.
Deposit date:2013-08-02
Release date:2014-04-02
Last modified:2014-06-04
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Selectively targeting an inactive conformation of interleukin-2-inducible T-cell kinase by allosteric inhibitors.
Biochem.J., 460, 2014
2JL4
  • Download 2jl4
  • View 2jl4
Molmil generated image of 2jl4
HOLO STRUCTURE OF MALEYL PYRUVATE ISOMERASE, A BACTERIAL GLUTATHIONE- S-TRANSFERASE IN ZETA CLASS
Descriptor:MALEYLPYRUVATE ISOMERASE, GLUTATHIONE
Authors:Shoemark, D.K., Y Zhou, N., Williams, P.A., Hadfield, A.T.
Deposit date:2008-09-04
Release date:2008-09-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of Bacterial Glutathione-S-Transferase Maleyl Pyruvate Isomerase and Implications for Mechanism of Isomerisation.
J.Mol.Biol., 384, 2008
2V6K
  • Download 2v6k
  • View 2v6k
Molmil generated image of 2v6k
STRUCTURE OF MALEYL PYRUVATE ISOMERASE, A BACTERIAL GLUTATHIONE-S- TRANSFERASE IN ZETA CLASS, IN COMPLEX WITH SUBSTRATE ANALOGUE DICARBOXYETHYL GLUTATHIONE
Descriptor:MALEYLPYRUVATE ISOMERASE, GAMMA-GLUTAMYL-S-(1,2-DICARBOXYETHYL)CYSTEINYLGLYCINE, SODIUM ION, ...
Authors:Shoemark, D.K., Zhou, N.-Y., Williams, P.A., Hadfield, A.T.
Deposit date:2007-07-19
Release date:2008-07-22
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure of Bacterial Glutathione-S-Transferase Maleyl Pyruvate Isomerase and Implications for Mechanism of Isomerisation.
J.Mol.Biol., 384, 2008
<12>