1TUF
| Crystal structure of Diaminopimelate Decarboxylase from m. jannaschi | Descriptor: | AZELAIC ACID, Diaminopimelate decarboxylase | Authors: | Rajashankar, K, Ray, S.R, Bonanno, J.B, Pinho, M.G, He, G, De Lencastre, H, Tomasz, A, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2004-06-24 | Release date: | 2004-07-20 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Cocrystal structures of diaminopimelate decarboxylase: mechanism, evolution, and inhibition of an antibiotic resistance accessory factor Structure, 10, 2002
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4BX9
| Human Vps33A in complex with a fragment of human Vps16 | Descriptor: | (2S)-2-hydroxybutanedioic acid, FORMIC ACID, MALONIC ACID, ... | Authors: | Graham, S.C, Wartosch, L, Gray, S.R, Scourfield, E.J, Deane, J.E, Luzio, J.P, Owen, D.J. | Deposit date: | 2013-07-09 | Release date: | 2013-07-24 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis of Vps33A recruitment to the human HOPS complex by Vps16. Proc. Natl. Acad. Sci. U.S.A., 110, 2013
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4BX8
| Human Vps33A | Descriptor: | CHLORIDE ION, VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 33A | Authors: | Graham, S.C, Wartosch, L, Gray, S.R, Scourfield, E.J, Deane, J.E, Luzio, J.P, Owen, D.J. | Deposit date: | 2013-07-09 | Release date: | 2013-07-24 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Basis of Vps33A Recruitment to the Human Hops Complex by Vps16. Proc.Natl.Acad.Sci.USA, 110, 2013
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4CZ2
| Complex of human VARP-ANKRD1 with Rab32-GppCp. Selenomet derivative. | Descriptor: | ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | Authors: | Perez-Dorado, I, Schaefer, I.B, McCoy, A.J, Owen, D.J, Evans, P.R. | Deposit date: | 2014-04-16 | Release date: | 2014-06-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.97 Å) | Cite: | Varp is Recruited on to Endosomes by Direct Interaction with Retromer, Where Together They Function in Export to the Cell Surface. Dev.Cell, 29, 2014
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8SIL
| Lysozyme crystallized in cyclic olefin copolymer-based microfluidic chips | Descriptor: | Lysozyme C | Authors: | Liu, Z, Gu, K, Shelby, M.L, Gilbile, D, Lyubimov, A.Y, Russi, S, Cohen, A.E, Coleman, M.A, Frank, M, Kuhl, T.L, Botha, S, Poitevin, F, Sierra, R.G. | Deposit date: | 2023-04-16 | Release date: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A user-friendly plug-and-play cyclic olefin copolymer-based microfluidic chip for room-temperature, fixed-target serial crystallography. Acta Crystallogr D Struct Biol, 79, 2023
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8SCY
| Lysozyme crystallized in cyclic olefin copolymer-based microfluidic chips | Descriptor: | Lysozyme C | Authors: | Liu, Z, Gu, K, Shelby, M.L, Gilbile, D, Lyubimov, A.Y, Russi, S, Cohen, A.E, Coleman, M.A, Frank, M, Kuhl, T.L. | Deposit date: | 2023-04-05 | Release date: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | A user-friendly plug-and-play cyclic olefin copolymer-based microfluidic chip for room-temperature, fixed-target serial crystallography. Acta Crystallogr D Struct Biol, 79, 2023
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7Z5C
| Chimera of AP2 with FCHO2 linker domain as a fusion on Cmu2 subunit | Descriptor: | AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | Authors: | Kane Dickson, V, Qu, K, Owen, D.J, Briggs, J.A, Zaccai, N.R. | Deposit date: | 2022-03-09 | Release date: | 2022-05-11 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.16 Å) | Cite: | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch. Sci Adv, 8, 2022
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7OG1
| AP2 clathrin adaptor core in complex with cargo peptide and FCHO2 | Descriptor: | AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | Authors: | Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. | Deposit date: | 2021-05-05 | Release date: | 2022-06-01 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch. Sci Adv, 8, 2022
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7OHO
| Crystal structure of AP2 FCHO2 chimera | Descriptor: | AP-2 complex subunit alpha-2, AP-2 complex subunit beta,F-BAR domain only protein 2, AP-2 complex subunit mu, ... | Authors: | Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. | Deposit date: | 2021-05-11 | Release date: | 2022-06-01 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.88 Å) | Cite: | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch. Sci Adv, 8, 2022
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7OHZ
| Crystal structure of AP2 Mu2 - FCHO2 chimera (His6-tagged) | Descriptor: | AP-2 complex subunit mu,F-BAR domain only protein 2 | Authors: | Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. | Deposit date: | 2021-05-11 | Release date: | 2022-06-01 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch. Sci Adv, 8, 2022
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7OI5
| Crystal structure of AP2 Mu2 - FCHO2 chimera (GST cleaved) | Descriptor: | AP-2 complex subunit mu,F-BAR domain only protein 2, GLYCEROL | Authors: | Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. | Deposit date: | 2021-05-11 | Release date: | 2022-06-01 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch. Sci Adv, 8, 2022
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7OFP
| Apo Structure of Mu2 Adaptin Subunit (Ap50) Of AP2 Clathrin Adaptor | Descriptor: | AP-2 complex subunit mu, CITRIC ACID, GLYCEROL | Authors: | Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. | Deposit date: | 2021-05-05 | Release date: | 2022-06-01 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch. Sci Adv, 8, 2022
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7OHI
| FCHO1-peptide-AP2 alpha ear complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, AP-2 complex subunit alpha-2, F-BAR domain only protein 1, ... | Authors: | Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. | Deposit date: | 2021-05-11 | Release date: | 2022-06-01 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.41 Å) | Cite: | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch. Sci Adv, 8, 2022
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7OIT
| Crystal structure of AP2 Mu2 in complex with FCHO2 WxxPhi motif (P3221 crystal form) | Descriptor: | AP-2 complex subunit mu, F-BAR domain only protein 2, GLYCEROL | Authors: | Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. | Deposit date: | 2021-05-12 | Release date: | 2022-06-01 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch. Sci Adv, 8, 2022
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7OIQ
| Crystal structure of AP2 Mu2 in complex with FCHO2 WxxPhi motif (C2 crystal form) | Descriptor: | AP-2 complex subunit mu, F-BAR domain only protein 2 | Authors: | Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. | Deposit date: | 2021-05-12 | Release date: | 2022-06-01 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch. Sci Adv, 8, 2022
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8FZW
| Thaumatin crystallized in cyclic olefin copolymer-based microfluidic chips | Descriptor: | L(+)-TARTARIC ACID, Thaumatin I | Authors: | Liu, Z, Gu, K, Shelby, M.L, Gilbile, D, Lyubimov, A.Y, Russi, S, Cohen, A.E, Coleman, M.A, Frank, M, Kuhl, T.L. | Deposit date: | 2023-01-30 | Release date: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | A user-friendly plug-and-play cyclic olefin copolymer-based microfluidic chip for room-temperature, fixed-target serial crystallography. Acta Crystallogr D Struct Biol, 79, 2023
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2VX8
| Vamp7 longin domain Hrb peptide complex | Descriptor: | CHLORIDE ION, NUCLEOPORIN-LIKE PROTEIN RIP, VESICLE-ASSOCIATED MEMBRANE PROTEIN 7 | Authors: | Evans, P.R, Owen, D.J, Luzio, J.P. | Deposit date: | 2008-07-01 | Release date: | 2008-09-16 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Molecular Basis for the Sorting of the Snare Vamp7 Into Endocytic Clathrin-Coated Vesicles by the Arfgap Hrb. Cell(Cambridge,Mass.), 134, 2008
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4AFI
| Complex between Vamp7 longin domain and fragment of delta-adaptin from AP3 | Descriptor: | AP-3 COMPLEX SUBUNIT DELTA-1, VESICLE-ASSOCIATED MEMBRANE PROTEIN 7, PRASEODYMIUM ION | Authors: | Kent, H.M, Evans, P.R, Luzio, J.P, Peden, A.A, Owen, D.J. | Deposit date: | 2012-01-19 | Release date: | 2012-05-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Basis of the Intracellular Sorting of the Snare Vamp7 by the Ap3 Adaptor Complex Dev.Cell, 22, 2012
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4B93
| Complex of Vamp7 cytoplasmic domain with 2nd ankyrin repeat domain of Varp | Descriptor: | ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27, VESICLE-ASSOCIATED MEMBRANE PROTEIN 7 | Authors: | Schaefer, I.B, Owen, D.J, Luzio, J.P, Evans, P.R. | Deposit date: | 2012-08-31 | Release date: | 2012-10-31 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Binding of Varp to Vamp7 Traps Vamp7 in a Closed, Fusogenically Inactive Conformation. Nat.Struct.Mol.Biol., 19, 2012
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5DE1
| Crystal structure of human IDH1 in complex with GSK321A | Descriptor: | (7R)-1-(4-fluorobenzyl)-N-{3-[(1S)-1-hydroxyethyl]phenyl}-7-methyl-5-(1H-pyrrol-2-ylcarbonyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxamide, Isocitrate dehydrogenase [NADP] cytoplasmic, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Concha, N.O, Smallwood, A, Qi, H. | Deposit date: | 2015-08-25 | Release date: | 2015-10-07 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | New IDH1 mutant inhibitors for treatment of acute myeloid leukemia. Nat.Chem.Biol., 11, 2015
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4CYM
| Complex of human VARP-ANKRD1 with Rab32-GppCp | Descriptor: | ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | Authors: | Perez-Dorado, I, Schaefer, I.B, McCoy, A.J, Owen, D.J, Evans, P.R. | Deposit date: | 2014-04-13 | Release date: | 2014-06-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Varp is Recruited on to Endosomes by Direct Interaction with Retromer, Where Together They Function in Export to the Cell Surface. Dev.Cell, 29, 2014
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