Author results

1EEA
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ACETYLCHOLINESTERASE
Descriptor:PROTEIN (ACETYLCHOLINESTERASE)
Authors:Raves, M.L., Giles, K., Schrag, J.D., Schmid, M.F., Phillips Jr., G.N., Wah, C., Howard, A.J., Silman, I., Sussman, J.L.
Deposit date:1999-01-26
Release date:1999-02-01
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Quaternary Structure of Tetrameric Acetylcholinesterase
Structure and Function of Cholinesterases and Related Proteins, 1998
1VOT
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ACETYLCHOLINESTERASE (E.C. 3.1.1.7) COMPLEXED WITH HUPERZINE A
Descriptor:ACETYLCHOLINESTERASE, Huperzine A
Authors:Raves, M.L., Harel, M., Silman, I., Sussman, J.L.
Deposit date:1996-06-23
Release date:1997-06-16
Last modified:2013-10-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of acetylcholinesterase complexed with the nootropic alkaloid, (-)-huperzine A.
Nat.Struct.Biol., 4, 1997
1AX9
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ACETYLCHOLINESTERASE COMPLEXED WITH EDROPHONIUM, LAUE DATA
Descriptor:ACETYLCHOLINESTERASE, EDROPHONIUM ION
Authors:Raves, M.L., Ravelli, R.B.G., Sussman, J.L., Harel, M., Silman, I.
Deposit date:1997-11-03
Release date:1998-02-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Static Laue diffraction studies on acetylcholinesterase.
Acta Crystallogr.,Sect.D, 54, 1998
2ACE
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NATIVE ACETYLCHOLINESTERASE (E.C. 3.1.1.7) FROM TORPEDO CALIFORNICA
Descriptor:ACETYLCHOLINESTERASE, ACETYLCHOLINE
Authors:Harel, M., Raves, M.L., Silman, I., Sussman, J.L.
Deposit date:1996-06-23
Release date:1996-11-08
Last modified:2016-06-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of acetylcholinesterase complexed with the nootropic alkaloid, (-)-huperzine A.
Nat.Struct.Biol., 4, 1997
2ACK
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ACETYLCHOLINESTERASE COMPLEXED WITH EDROPHONIUM, MONOCHROMATIC DATA
Descriptor:ACETYLCHOLINESTERASE, EDROPHONIUM ION
Authors:Raves, M.L., Sussman, J.L., Harel, M., Silman, I.
Deposit date:1997-10-29
Release date:1998-02-11
Last modified:2016-06-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Static Laue diffraction studies on acetylcholinesterase.
Acta Crystallogr.,Sect.D, 54, 1998
1GQR
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ACETYLCHOLINESTERASE (E.C. 3.1.1.7) COMPLEXED WITH RIVASTIGMINE
Descriptor:ACETYLCHOLINESTERASE, N-ACETYL-D-GLUCOSAMINE, 3-[(1S)-1-(DIMETHYLAMINO)ETHYL]PHENOL, ...
Authors:Raves, M.L., Harel, M., Silman, I., Sussman, J.L.
Deposit date:2001-12-04
Release date:2002-03-15
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Kinetic and Structural Studies on the Interaction of Cholinesterases with the Anti-Alzheimer Drug Rivastigmine
Biochemistry, 41, 2002
1CFJ
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METHYLPHOSPHONYLATED ACETYLCHOLINESTERASE (AGED) OBTAINED BY REACTION WITH O-ISOPROPYLMETHYLPHOSPHONOFLUORIDATE (GB, SARIN)
Descriptor:PROTEIN (ACETYLCHOLINESTERASE), N-ACETYL-D-GLUCOSAMINE, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
Authors:Millard, C.B., Silman, I., Sussman, J.L.
Deposit date:1999-03-19
Release date:1999-06-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of aged phosphonylated acetylcholinesterase: nerve agent reaction products at the atomic level.
Biochemistry, 38, 1999
1SOM
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TORPEDO CALIFORNICA ACETYLCHOLINESTERASE INHIBITED BY NERVE AGENT GD (SOMAN).
Descriptor:PROTEIN (ACETYLCHOLINESTERASE), N-ACETYL-D-GLUCOSAMINE, UNKNOWN ATOM OR ION, ...
Authors:Greenblatt, H.M., Millard, C.B., Sussman, J.L., Silman, I.
Deposit date:1999-03-17
Release date:1999-06-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of aged phosphonylated acetylcholinesterase: nerve agent reaction products at the atomic level.
Biochemistry, 38, 1999
1QID
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SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT A) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE
Descriptor:ACETYLCHOLINESTERASE
Authors:Kryger, G., Weik, M., Ravelli, R.B.G.
Deposit date:1999-06-13
Release date:2000-01-28
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Specific chemical and structural damage to proteins produced by synchrotron radiation.
Proc.Natl.Acad.Sci.USA, 97, 2000
1QIE
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SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT B) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE
Descriptor:ACETYLCHOLINESTERASE
Authors:Kryger, G., Weik, M., Ravelli, R.B.G.
Deposit date:1999-06-14
Release date:2000-01-28
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Specific chemical and structural damage to proteins produced by synchrotron radiation.
Proc.Natl.Acad.Sci.USA, 97, 2000
1QIF
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SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT C) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE
Descriptor:ACETYLCHOLINESTERASE
Authors:Kryger, G., Weik, M., Ravelli, R.B.G.
Deposit date:1999-06-14
Release date:2000-01-28
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Specific chemical and structural damage to proteins produced by synchrotron radiation.
Proc.Natl.Acad.Sci.USA, 97, 2000
1QIG
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SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT D) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE
Descriptor:ACETYLCHOLINESTERASE
Authors:Kryger, G., Weik, M., Ravelli, R.B.G.
Deposit date:1999-06-14
Release date:2000-01-28
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Specific chemical and structural damage to proteins produced by synchrotron radiation.
Proc.Natl.Acad.Sci.USA, 97, 2000
1QIH
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SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT E) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE
Descriptor:PROTEIN (ACETYLCHOLINESTERASE)
Authors:Kryger, G., Weik, M., Ravelli, R.B.G.
Deposit date:1999-06-14
Release date:2000-01-28
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Specific chemical and structural damage to proteins produced by synchrotron radiation.
Proc.Natl.Acad.Sci.USA, 97, 2000
1QII
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SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT F) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE
Descriptor:ACETYLCHOLINESTERASE
Authors:Kryger, G., Weik, M., Ravelli, R.B.G.
Deposit date:1999-06-14
Release date:2000-01-28
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Specific chemical and structural damage to proteins produced by synchrotron radiation.
Proc.Natl.Acad.Sci.USA, 97, 2000
1QIJ
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SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT G) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE
Descriptor:ACETYLCHOLINESTERASE
Authors:Kryger, G., Weik, M., Ravelli, R.B.G.
Deposit date:1999-06-14
Release date:2000-01-28
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Specific chemical and structural damage to proteins produced by synchrotron radiation.
Proc.Natl.Acad.Sci.USA, 97, 2000
1QIK
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SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT H) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE
Descriptor:ACETYLCHOLINESTERASE
Authors:Kryger, G., Weik, M., Ravelli, R.B.G.
Deposit date:1999-06-14
Release date:2000-01-28
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Specific chemical and structural damage to proteins produced by synchrotron radiation.
Proc.Natl.Acad.Sci.USA, 97, 2000
1QIM
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SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT I) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE
Descriptor:ACETYLCHOLINESTERASE
Authors:Kryger, G., Weik, M., Ravelli, R.B.G.
Deposit date:1999-06-14
Release date:2000-01-28
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (3 Å)
Cite:Specific chemical and structural damage to proteins produced by synchrotron radiation.
Proc.Natl.Acad.Sci.USA, 97, 2000
1QIO
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SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE CAUSED BY INTENSE SYNCHROTRON RADIATION TO HEN EGG WHITE LYSOZYME
Descriptor:LYSOZYME, SODIUM ION, CHLORIDE ION
Authors:Kryger, G., Weik, M., Ravelli, R.B.
Deposit date:1999-06-14
Release date:2001-04-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Specific chemical and structural damage to proteins produced by synchrotron radiation.
Proc.Natl.Acad.Sci.USA, 97, 2000
2DFP
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X-RAY STRUCTURE OF AGED DI-ISOPROPYL-PHOSPHORO-FLUORIDATE (DFP) BOUND TO ACETYLCHOLINESTERASE
Descriptor:PROTEIN (ACETYLCHOLINESTERASE), N-ACETYL-D-GLUCOSAMINE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Kryger, G., Millard, C.B., Silman, I., Sussman, J.L.
Deposit date:1998-12-07
Release date:1999-06-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of aged phosphonylated acetylcholinesterase: nerve agent reaction products at the atomic level.
Biochemistry, 38, 1999
1H22
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STRUCTURE OF ACETYLCHOLINESTERASE (E.C. 3.1.1.7) COMPLEXED WITH (S,S)-(-)-BIS(10)-HUPYRIDONE AT 2.15A RESOLUTION
Descriptor:ACETYLCHOLINESTERASE, (S,S)-(-)-N,N'-DI-5'-[5',6',7',8'-TETRAHYDRO- 2'(1'H)-QUINOLYNYL]-1,10-DIAMINODECANE DIHYDROCHLORIDE, N-ACETYL-D-GLUCOSAMINE
Authors:Wong, D.M., Greenblatt, H.M., Carlier, P.R., Han, Y.-F., Pang, Y.-P., Silman, I., Sussman, J.L.
Deposit date:2002-07-30
Release date:2002-12-23
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Acetylcholinesterase Complexed with Bivalent Ligands Related to Huperzine A: Experimental Evidence for Species-Dependent Protein-Ligand Complementarity
J.Am.Chem.Soc., 125, 2003
1H23
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STRUCTURE OF ACETYLCHOLINESTERASE (E.C. 3.1.1.7) COMPLEXED WITH (S,S)-(-)-BIS(12)-HUPYRIDONE AT 2.15A RESOLUTION
Descriptor:ACETYLCHOLINESTERASE, (S,S)-(-)-N,N'-DI-5'-[5',6',7',8'-TETRAHYDRO- 2'(1'H)-QUINOLYNYL]-1,12-DIAMINODODECANE DIHYDROCHLORIDE, N-ACETYL-D-GLUCOSAMINE
Authors:Wong, D.M., Greenblatt, H.M., Carlier, P.R., Han, Y.F., Pang, Y.P., Silman, I., Sussman, J.L.
Deposit date:2002-07-30
Release date:2002-12-23
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Acetylcholinesterase Complexed with Bivalent Ligands Related to Huperzine A: Experimental Evidence for Species-Dependent Protein-Ligand Complementarity
J.Am.Chem.Soc., 125, 2003
1ZGB
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CRYSTAL STRUCTURE OF TORPEDO CALIFORNICA ACETYLCHOLINESTERASE IN COMPLEX WITH AN (R)-TACRINE(10)-HUPYRIDONE INHIBITOR.
Descriptor:Acetylcholinesterase, N-ACETYL-D-GLUCOSAMINE, (5R)-5-{[10-(1,2,3,4-TETRAHYDROACRIDIN-9-YLAMINO)DECYL]AMINO}-5,6,7,8-TETRAHYDROQUINOLIN-2(1H)-ONE
Authors:Haviv, H., Wong, D.M., Greenblatt, H.M., Carlier, P.R., Pang, Y.P., Silman, I., Sussman, J.L., Israel Structural Proteomics Center (ISPC)
Deposit date:2005-04-21
Release date:2005-08-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Packing Mediates Enantioselective Ligand Recognition at the Peripheral Site of Acetylcholinesterase
J.Am.Chem.Soc., 127, 2005