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7CZB
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BU of 7czb by Molmil
The cryo-EM structure of the ERAD retrotranslocation channel formed by human Derlin-1
Descriptor: Derlin-1
Authors:Rao, B, Li, S, Yao, D, Wang, Q, Xia, Y, Jia, Y, Shen, Y, Cao, Y.
Deposit date:2020-09-07
Release date:2021-03-17
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:The cryo-EM structure of an ERAD protein channel formed by tetrameric human Derlin-1.
Sci Adv, 7, 2021
7Y53
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BU of 7y53 by Molmil
The cryo-EM structure of human ERAD retro-translocation complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Derlin-1, Transitional endoplasmic reticulum ATPase
Authors:Cao, Y, Rao, B, Wang, Q, Yao, D, Xia, Y, Li, W, Li, S, Shen, Y.
Deposit date:2022-06-16
Release date:2023-10-18
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (3.61 Å)
Cite:The cryo-EM structure of the human ERAD retrotranslocation complex.
Sci Adv, 9, 2023
7Y59
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BU of 7y59 by Molmil
The cryo-EM structure of human ERAD retro-translocation complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Derlin-1, ...
Authors:Cao, Y, Rao, B, Wang, Q, Yao, D, Xia, Y, Li, W, Li, S, Shen, Y.
Deposit date:2022-06-16
Release date:2023-10-18
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (4.51 Å)
Cite:The cryo-EM structure of the human ERAD retrotranslocation complex.
Sci Adv, 9, 2023
7Y4W
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BU of 7y4w by Molmil
The cryo-EM structure of human ERAD retro-translocation complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Derlin-1, Transitional endoplasmic reticulum ATPase
Authors:Cao, Y, Rao, B, Wang, Q, Yao, D, Xia, Y, Li, W, Li, S, Shen, Y.
Deposit date:2022-06-16
Release date:2023-10-18
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:The cryo-EM structure of the human ERAD retrotranslocation complex.
Sci Adv, 9, 2023
6EBA
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BU of 6eba by Molmil
Crystal Structure of A Bacterial Homolog to Human Lysosomal Transporter, Spinster, in Inward-facing And Unoccupied Conformation
Descriptor: Major facilitator family transporter
Authors:Zhou, F, Yao, D, Rao, B, Zhang, L, Cao, Y.
Deposit date:2018-08-06
Release date:2019-08-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.812 Å)
Cite:Crystal structure of a bacterial homolog to human lysosomal transporter, spinster
Sci Bull (Beijing), 64, 2019
6E8J
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BU of 6e8j by Molmil
Crystal Structure of A Bacterial Homolog to Human Lysosomal Transporter, Spinster, in Inward-facing And Occupied Conformation
Descriptor: Major facilitator family transporter
Authors:Zhou, F, Yao, D, Rao, B, Zhang, L, Cao, Y.
Deposit date:2018-07-30
Release date:2019-08-14
Last modified:2020-01-08
Method:X-RAY DIFFRACTION (3.091 Å)
Cite:Crystal structure of a bacterial homolog to human lysosomal transporter, spinster
Sci Bull (Beijing), 64, 2019
6E9C
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BU of 6e9c by Molmil
Selenomethionine Derivative Structure of A Bacterial Homolog to Human Lysosomal Transporter, Spinster
Descriptor: Major facilitator family transporter
Authors:Zhou, F, Yao, D, Rao, B, Zhang, L, Cao, Y.
Deposit date:2018-07-31
Release date:2019-08-14
Last modified:2020-01-08
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of a bacterial homolog to human lysosomal transporter, spinster
Sci Bull (Beijing), 64, 2019
8GVC
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BU of 8gvc by Molmil
The cryo-EM structure of hAE2 with bicarbonate
Descriptor: Anion exchange protein 2, BICARBONATE ION
Authors:Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y.
Deposit date:2022-09-14
Release date:2023-04-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:The structural basis of the pH-homeostasis mediated by the Cl - /HCO 3 - exchanger, AE2.
Nat Commun, 14, 2023
8GVF
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BU of 8gvf by Molmil
The outward-facing structure of hAE2 in basic pH
Descriptor: Anion exchange protein 2
Authors:Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y.
Deposit date:2022-09-15
Release date:2023-04-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:The structural basis of the pH-homeostasis mediated by the Cl - /HCO 3 - exchanger, AE2.
Nat Commun, 14, 2023
8GVH
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BU of 8gvh by Molmil
Human AE2 in acidic KNO3
Descriptor: Anion exchange protein 2, CHOLESTEROL HEMISUCCINATE
Authors:Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y.
Deposit date:2022-09-15
Release date:2023-04-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:The structural basis of the pH-homeostasis mediated by the Cl - /HCO 3 - exchanger, AE2.
Nat Commun, 14, 2023
8GV9
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BU of 8gv9 by Molmil
The cryo-EM structure of hAE2 with chloride ion
Descriptor: Anion exchange protein 2, CHLORIDE ION
Authors:Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y.
Deposit date:2022-09-14
Release date:2023-04-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:The structural basis of the pH-homeostasis mediated by the Cl - /HCO 3 - exchanger, AE2.
Nat Commun, 14, 2023
8GVA
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BU of 8gva by Molmil
The intermediate structure of hAE2 in basic pH
Descriptor: Anion exchange protein 2
Authors:Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y.
Deposit date:2022-09-14
Release date:2023-04-12
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:The structural basis of the pH-homeostasis mediated by the Cl - /HCO 3 - exchanger, AE2.
Nat Commun, 14, 2023
8GVE
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BU of 8gve by Molmil
The asymmetry structure of hAE2
Descriptor: Anion exchange protein 2
Authors:Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y.
Deposit date:2022-09-15
Release date:2023-04-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:The structural basis of the pH-homeostasis mediated by the Cl - /HCO 3 - exchanger, AE2.
Nat Commun, 14, 2023
8GV8
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BU of 8gv8 by Molmil
The cryo-EM structure of hAE2 with DIDS
Descriptor: 2,2'-ethane-1,2-diylbis{5-[(sulfanylmethyl)amino]benzenesulfonic acid}, Anion exchange protein 2
Authors:Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y.
Deposit date:2022-09-14
Release date:2023-04-12
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:The structural basis of the pH-homeostasis mediated by the Cl - /HCO 3 - exchanger, AE2.
Nat Commun, 14, 2023
8K0I
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BU of 8k0i by Molmil
Human collagen prolyl processing enzyme complex, P3H1/CRTAP/PPIB heterotrimer, in its dual-ternary state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cartilage-associated protein, Peptidyl-prolyl cis-trans isomerase B, ...
Authors:Li, W, Peng, J, Yao, D, Rao, B, Xia, Y, Wang, Q, Li, S, Cao, M, Shen, Y, Ma, P, Liao, R, Qin, A, Zhao, J, Cao, Y.
Deposit date:2023-07-09
Release date:2024-09-18
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:The structural basis for the collagen processing by human P3H1/CRTAP/PPIB ternary complex.
Nat Commun, 15, 2024
8K0M
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BU of 8k0m by Molmil
Human collagen prolyl processing enzyme complex, P3H1/CRTAP/PPIB heterotrimer, bound to 2-oxoglutarate
Descriptor: 2-OXOGLUTARIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Cartilage-associated protein, ...
Authors:Li, W, Peng, J, Yao, D, Rao, B, Xia, Y, Wang, Q, Li, S, Cao, M, Shen, Y, Ma, P, Liao, R, Qin, A, Zhao, J, Cao, Y.
Deposit date:2023-07-09
Release date:2024-09-18
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:The structural basis for the collagen processing by human P3H1/CRTAP/PPIB ternary complex.
Nat Commun, 15, 2024
8K17
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BU of 8k17 by Molmil
Human collagen prolyl processing enzyme complex, P3H1/CRTAP/PPIB heterotrimer, bound to collagen alpha-1(I) chain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cartilage-associated protein, FE (III) ION, ...
Authors:Li, W, Peng, J, Yao, D, Rao, B, Xia, Y, Wang, Q, Li, S, Cao, M, Shen, Y, Ma, P, Liao, R, Qin, A, Zhao, J, Cao, Y.
Deposit date:2023-07-10
Release date:2024-09-18
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:The structural basis for the collagen processing by human P3H1/CRTAP/PPIB ternary complex.
Nat Commun, 15, 2024
8KC9
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BU of 8kc9 by Molmil
Human collagen prolyl processing enzyme complex, P3H1/CRTAP/PPIB heterotrimer, bound to cyclosporin A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cartilage-associated protein, DSN-MLE-MLE-MVA-BMT-ABA-SAR-MLE-VAL-MLE-ALA, ...
Authors:Li, W, Peng, J, Yao, D, Rao, B, Xia, Y, Wang, Q, Li, S, Cao, M, Shen, Y, Ma, P, Liao, R, Qin, A, Zhao, J, Cao, Y.
Deposit date:2023-08-06
Release date:2024-09-18
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:The structural basis for the collagen processing by human P3H1/CRTAP/PPIB ternary complex.
Nat Commun, 15, 2024
8K0F
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BU of 8k0f by Molmil
Human collagen prolyl processing enzyme complex, P3H1/CRTAP/PPIB heterotrimer, in its apo state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cartilage-associated protein, FE (III) ION, ...
Authors:Li, W, Peng, J, Yao, D, Rao, B, Xia, Y, Wang, Q, Li, S, Cao, M, Shen, Y, Ma, P, Liao, R, Qin, A, Zhao, J, Cao, Y.
Deposit date:2023-07-08
Release date:2024-09-18
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:The structural basis for the collagen processing by human P3H1/CRTAP/PPIB ternary complex.
Nat Commun, 15, 2024
8K0E
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BU of 8k0e by Molmil
Human collagen prolyl processing enzyme complex, P3H1/CRTAP heterodimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cartilage-associated protein, FE (III) ION, ...
Authors:Li, W, Peng, J, Yao, D, Rao, B, Xia, Y, Wang, Q, Li, S, Cao, M, Shen, Y, Ma, P, Liao, R, Qin, A, Zhao, J, Cao, Y.
Deposit date:2023-07-08
Release date:2024-09-18
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:The structural basis for the collagen processing by human P3H1/CRTAP/PPIB ternary complex.
Nat Commun, 15, 2024
7F3X
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BU of 7f3x by Molmil
Lysophospholipid acyltransferase LPCAT3 in complex with lysophosphatidylcholine
Descriptor: LPCAT3, [2-((1-OXODODECANOXY-(2-HYDROXY-3-PROPANYL))-PHOSPHONATE-OXY)-ETHYL]-TRIMETHYLAMMONIUM
Authors:Zhang, Q, Yao, D, Rao, B, Li, S, Jian, L, Chen, Y, Hu, K, Xia, Y, Shen, Y, Cao, Y.
Deposit date:2021-06-17
Release date:2021-12-01
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:The structural basis for the phospholipid remodeling by lysophosphatidylcholine acyltransferase 3.
Nat Commun, 12, 2021
7EWT
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BU of 7ewt by Molmil
The crystal structure of Lysophospholipid acyltransferase LPCAT3 (MOBAT5) in its monomeric and apo form
Descriptor: Lysophospholipid acyltransferase 5
Authors:Zhang, Q, Yao, D, Rao, B, Li, S, Jian, L, Chen, Y, Hu, K, Xia, Y, Cao, Y.
Deposit date:2021-05-26
Release date:2021-12-01
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:The structural basis for the phospholipid remodeling by lysophosphatidylcholine acyltransferase 3.
Nat Commun, 12, 2021
7F40
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BU of 7f40 by Molmil
Lysophospholipid acyltransferase LPCAT3 in a complex with Arachidonoyl-CoA
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, LPCAT3, S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenethioate
Authors:Zhang, Q, Yao, D, Rao, B, Li, S, Jian, L, Chen, Y, Hu, K, Xia, Y, Shen, Y, Cao, Y.
Deposit date:2021-06-17
Release date:2021-12-01
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:The structural basis for the phospholipid remodeling by lysophosphatidylcholine acyltransferase 3.
Nat Commun, 12, 2021
7YIV
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BU of 7yiv by Molmil
The Crystal Structure of Human Tissue Nonspecific Alkaline Phosphatase (ALPL) at Basic pH
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alkaline phosphatase, ...
Authors:Cao, Y, Qin, A, Yu, Y.T, Yao, D.Q, Zhang, Q, Rao, B, Xia, Y, Lu, Y.
Deposit date:2022-07-18
Release date:2023-07-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:The structural pathology for hypophosphatasia caused by malfunctional tissue non-specific alkaline phosphatase.
Nat Commun, 14, 2023
7YIW
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BU of 7yiw by Molmil
The Crystal Structure of Human Tissue Nonspecific Alkaline Phosphatase (ALPL) at Acidic pH
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alkaline phosphatase, ...
Authors:Yu, Y.T, Yao, D.Q, Zhang, Q, Rao, B, Xia, Y, Lu, Y, Qin, A, Cao, Y.
Deposit date:2022-07-18
Release date:2023-07-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:The structural pathology for hypophosphatasia caused by malfunctional tissue non-specific alkaline phosphatase.
Nat Commun, 14, 2023

 

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