Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
1H8B
DownloadVisualize
BU of 1h8b by Molmil
EF-hands 3,4 from alpha-actinin / Z-repeat 7 from titin
Descriptor: ALPHA-ACTININ 2, SKELETAL MUSCLE ISOFORM, TITIN
Authors:Atkinson, R.A, Joseph, C, Kelly, G, Muskett, F.W, Frenkiel, T.A, Nietlispach, D, Pastore, A.
Deposit date:2001-02-01
Release date:2001-08-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Ca2+-Independent Binding of an EF-Hand Domain to a Novel Motif in the Alpha-Actinin-Titin Complex
Nat.Struct.Biol., 8, 2001
9BIW
DownloadVisualize
BU of 9biw by Molmil
Crystal structure of Chelona Toxin, a diphtheria toxin homolog, from Austwickia chelonae
Descriptor: CALCIUM ION, Chelona Toxin
Authors:Gill, S.K, Sugiman-Marangos, S.N, Melnyk, R.A.
Deposit date:2024-04-24
Release date:2024-08-07
Method:X-RAY DIFFRACTION (2.496 Å)
Cite:A diphtheria toxin-like intracellular delivery platform that evades pre-existing antidrug antibodies
Embo Mol Med
5FQR
DownloadVisualize
BU of 5fqr by Molmil
Selective estrogen receptor downregulator antagonists: Tetrahydroisoquinoline phenols 2.
Descriptor: (E)-3-[4-[(1R)-6-HYDROXY-2-ISOBUTYL-3,4-DIHYDRO-1H-ISOQUINOLIN-1-YL]PHENYL]PROP-2-ENOIC ACID, ESTROGEN RECEPTOR
Authors:Scott, J.S, Bailey, A, Davies, R.D.M, Degorce, S.L, MacFaul, P.A, Gingell, H, Moss, T, Norman, R.A, Pink, J.H, Rabow, A.A, Roberts, B, Smith, P.D.
Deposit date:2015-12-14
Release date:2016-02-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Tetrahydroisoquinoline Phenols: Selective Estrogen Receptor Downregulator Antagonists with Oral Bioavailability in Rat.
Acs Med.Chem.Lett., 7, 2016
5FQS
DownloadVisualize
BU of 5fqs by Molmil
Selective estrogen receptor downregulator antagonists: Tetrahydroisoquinoline phenols 3.
Descriptor: (E)-3-[4-(6-HYDROXY-2-ISOBUTYL-1-METHYL-3,4-DIHYDROISOQUINOLIN-1-YL)PHENYL]PROP-2-ENOIC ACID, ESTROGEN RECEPTOR
Authors:Scott, J.S, Bailey, A, Davies, R.D.M, Degorce, S.L, MacFaul, P.A, Gingell, H, Moss, T, Norman, R.A, Pink, J.H, Rabow, A.A, Roberts, B, Smith, P.D.
Deposit date:2015-12-14
Release date:2016-02-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Tetrahydroisoquinoline Phenols: Selective Estrogen Receptor Downregulator Antagonists with Oral Bioavailability in Rat.
Acs Med.Chem.Lett., 7, 2016
2KPK
DownloadVisualize
BU of 2kpk by Molmil
MAGI-1 PDZ1
Descriptor: Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1
Authors:Charbonnier, S, Nomine, Y, Ramirez, J, Luck, K, Stote, R.H, Trave, G, Kieffer, B, Atkinson, R.A.
Deposit date:2009-10-16
Release date:2010-10-27
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:The structural and dynamic response of MAGI-1 PDZ1 with non-canonical domain boundaries to binding of human papillomavirus (HPV) E6
J.Mol.Biol., 2011
5WEN
DownloadVisualize
BU of 5wen by Molmil
GluA2 bound to GSG1L in digitonin, state 2
Descriptor: Digitonin, Glutamate receptor 2,Germ cell-specific gene 1-like protein
Authors:Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I.
Deposit date:2017-07-10
Release date:2017-08-02
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:Channel opening and gating mechanism in AMPA-subtype glutamate receptors.
Nature, 549, 2017
4V4B
DownloadVisualize
BU of 4v4b by Molmil
Structure of the ribosomal 80S-eEF2-sordarin complex from yeast obtained by docking atomic models for RNA and protein components into a 11.7 A cryo-EM map.
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S11, ...
Authors:Spahn, C.M, Gomez-Lorenzo, M.G, Grassucci, R.A, Jorgensen, R, Andersen, G.R, Beckmann, R, Penczek, P.A, Ballesta, J.P.G, Frank, J.
Deposit date:2004-01-06
Release date:2014-07-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (11.7 Å)
Cite:Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation.
Embo J., 23, 2004
4LQY
DownloadVisualize
BU of 4lqy by Molmil
Crystal Structure of Human ENPP4 with AMP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE MONOPHOSPHATE, ...
Authors:Albright, R.A, Braddock, D.T.
Deposit date:2013-07-19
Release date:2013-12-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Molecular basis of purinergic signal metabolism by ectonucleotide pyrophosphatase/phosphodiesterases 4 and 1 and implications in stroke.
J.Biol.Chem., 289, 2014
2WOT
DownloadVisualize
BU of 2wot by Molmil
ALK5 IN COMPLEX WITH 4-((5,6-dimethyl-2-(2-pyridyl)-3-pyridyl)oxy)-N-(3,4,5-trimethoxyphenyl)pyridin-2-amine
Descriptor: 1,2-ETHANEDIOL, 4-[(5,6-DIMETHYL-2,2'-BIPYRIDIN-3-YL)OXY]-N-(3,4,5-TRIMETHOXYPHENYL)PYRIDIN-2-AMINE, TGF-BETA RECEPTOR TYPE-1
Authors:Norman, R.A, Debreczeni, J.E, Goldberg, F.W, Ward, R.A, Finlay, R, Powell, S.J, Roberts, N.J, Dishington, A.P, Gingell, H.J, Wickson, K.F, Roberts, A.L.
Deposit date:2009-07-28
Release date:2009-09-22
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Rapid Generation of a High Quality Lead for Transforming Growth Factor-Beta (Tgf-Beta) Type I Receptor (Alk5).
J.Med.Chem., 52, 2009
1H00
DownloadVisualize
BU of 1h00 by Molmil
CDK2 in complex with a disubstituted 4, 6-bis anilino pyrimidine CDK4 inhibitor
Descriptor: (2R)-1-[4-({6-[(2,6-DIFLUOROPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)PHENOXY]-3-(DIMETHYLAMINO)PROPAN-2-OL, (2S)-1-[4-({6-[(2,6-DIFLUOROPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)PHENOXY]-3-(DIMETHYLAMINO)PROPAN-2-OL, CELL DIVISION PROTEIN KINASE 2
Authors:Beattie, J.F, Breault, G.A, Ellston, R.P.A, Green, S, Jewsbury, P.J, Midgley, C.J, Naven, R.T, Minshull, C.A, Pauptit, R.A, Tucker, J.A, Pease, J.E.
Deposit date:2002-06-10
Release date:2003-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Cyclin-Dependent Kinase 4 Inhibitors as a Treatment for Cancer. Part 1: Identification and Optimisation of Substituted 4,6-Bis Anilino Pyrimidines
Bioorg.Med.Chem.Lett., 13, 2003
1H59
DownloadVisualize
BU of 1h59 by Molmil
Complex of IGFBP-5 with IGF-I
Descriptor: INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 5, INSULIN-LIKE GROWTH FACTOR IA
Authors:Zeslawski, W, Beisel, H.G, Kamionka, M, Kalus, W, Engh, R.A, Huber, R, Holak, T.A.
Deposit date:2001-05-21
Release date:2002-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Interaction of Insulin-Like Growth Factor-I with the N-Terminal Domain of Igfbp-5
Embo J., 20, 2001
1H1I
DownloadVisualize
BU of 1h1i by Molmil
CRYSTAL STRUCTURE OF QUERCETIN 2,3-DIOXYGENASE ANAEROBICALLY COMPLEXED WITH THE SUBSTRATE QUERCETN
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Steiner, R.A, Dijkstra, B.W.
Deposit date:2002-07-15
Release date:2002-11-28
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Anaerobic Enzyme.Substrate Structures Provide Insight Into the Reaction Mechanism of the Copper- Dependent Quercetin 2,3-Dioxygenase.
Proc.Natl.Acad.Sci.USA, 99, 2002
9BIV
DownloadVisualize
BU of 9biv by Molmil
Crystal Structure of Ubc13 with a New Active Site Loop Conformation
Descriptor: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
Authors:Farraj, R.A, Edwards, R.A, Glover, J.N.M.
Deposit date:2024-04-24
Release date:2024-05-08
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Crystal Structure of Ubc13 with a New Active Site Loop Conformation
To Be Published
6F9H
DownloadVisualize
BU of 6f9h by Molmil
Crystal structure of Barley Beta-Amylase complexed with 4-S-alpha-D-glucopyranosyl-(1,4-dideoxy-4-thio-nojirimycin)
Descriptor: 1,4-dideoxy-4-thio-nojirimycin, Beta-amylase, CHLORIDE ION, ...
Authors:Moncayo, M.A, Rodrigues, L.L, Stevenson, C.E.M, Ruzanski, C, Rejzek, M, Lawson, D.M, Angulo, J, Field, R.A.
Deposit date:2017-12-14
Release date:2019-01-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Synthesis, biological and structural analysis of prospective glycosyl-iminosugar prodrugs: impact on germination
To be published
6F9L
DownloadVisualize
BU of 6f9l by Molmil
Crystal structure of Barley Beta-Amylase complexed with 3-Deoxy-3-fluoro-maltose
Descriptor: Beta-amylase, CHLORIDE ION, alpha-D-glucopyranose-(1-4)-3-deoxy-3-fluoro-alpha-D-glucopyranose
Authors:Tantanarat, K, Stevenson, C.E.M, Rejzek, M, Lawson, D.M, Field, R.A.
Deposit date:2017-12-14
Release date:2019-01-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Crystal structure of Barley Beta-Amylase complexed with 3-Deoxy-3-fluoro-maltose
To be published
1QGT
DownloadVisualize
BU of 1qgt by Molmil
HUMAN HEPATITIS B VIRAL CAPSID (HBCAG)
Descriptor: PROTEIN (HBV CAPSID PROTEIN)
Authors:Leslie, A.G.W, Wynne, S.A, Crowther, R.A.
Deposit date:1999-05-05
Release date:1999-06-25
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The crystal structure of the human hepatitis B virus capsid.
Mol.Cell, 3, 1999
3RJQ
DownloadVisualize
BU of 3rjq by Molmil
Crystal structure of anti-HIV llama VHH antibody A12 in complex with C186 gp120
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, C186 gp120, Llama VHH A12
Authors:Chen, L, McLellan, J.S, Kwon, Y.D, Schmidt, S, Wu, X, Zhou, T, Yang, Y, Zhang, B, Forsman, A, Weiss, R.A, Verrips, T, Mascola, J, Kwong, P.D.
Deposit date:2011-04-15
Release date:2012-05-02
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Crystal structure of anti-HIV A12 VHH of llama antibody in complex with C1086 gp120
To be Published
5FM5
DownloadVisualize
BU of 5fm5 by Molmil
Crystal structure of the myomesin:obscurin-like-1 complex
Descriptor: MYOMESIN-1, OBSCURIN-LIKE-1
Authors:Pernigo, S, Steiner, R.A.
Deposit date:2015-11-01
Release date:2016-11-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Binding of Myomesin to Obscurin-Like-1 at the Muscle M-Band Provides a Strategy for Isoform-Specific Mechanical Protection.
Structure, 25, 2017
5FN7
DownloadVisualize
BU of 5fn7 by Molmil
Crystal structure of human CD45 extracellular region, domains d1-d2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MERCURY (II) ION, RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C
Authors:Chang, V.T, Fernandes, R.A, Ganzinger, K.A, Lee, S.F, Siebold, C, McColl, J, Jonsson, P, Palayret, M, Harlos, K, Coles, C.H, Jones, E.Y, Lui, Y, Huang, E, Gilbert, R.J.C, Klenerman, D, Aricescu, A.R, Davis, S.J.
Deposit date:2015-11-10
Release date:2016-03-23
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Initiation of T Cell Signaling by Cd45 Segregation at 'Close Contacts'.
Nat.Immunol., 17, 2016
3S1I
DownloadVisualize
BU of 3s1i by Molmil
Crystal structure of oxygen-bound hell's gate globin I
Descriptor: Hemoglobin-like flavoprotein, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Teh, A.H, Saito, J.A, Baharuddin, A, Tuckerman, J.R, Newhouse, J.S, Kanbe, M, Newhouse, E.I, Rahim, R.A, Favier, F, Didierjean, C, Sousa, E.H.S, Stott, M.B, Dunfield, P.F, Gonzalez, G, Gilles-Gonzalez, M.A, Najimudin, N, Alam, M.
Deposit date:2011-05-15
Release date:2011-09-21
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Hell's Gate globin I: an acid and thermostable bacterial hemoglobin resembling mammalian neuroglobin
Febs Lett., 585, 2011
3S1J
DownloadVisualize
BU of 3s1j by Molmil
Crystal structure of acetate-bound hell's gate globin I
Descriptor: ACETATE ION, Hemoglobin-like flavoprotein, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Teh, A.H, Saito, J.A, Baharuddin, A, Tuckerman, J.R, Newhouse, J.S, Kanbe, M, Newhouse, E.I, Rahim, R.A, Favier, F, Didierjean, C, Sousa, E.H.S, Stott, M.B, Dunfield, P.F, Gonzalez, G, Gilles-Gonzalez, M.A, Najimudin, N, Alam, M.
Deposit date:2011-05-15
Release date:2011-09-21
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Hell's Gate globin I: an acid and thermostable bacterial hemoglobin resembling mammalian neuroglobin
Febs Lett., 585, 2011
5FM4
DownloadVisualize
BU of 5fm4 by Molmil
Structure of the C-terminally extended domain My4 of human myomesin (space group P21)
Descriptor: MYOMESIN-1
Authors:Pernigo, S, Steiner, R.A.
Deposit date:2015-10-30
Release date:2016-11-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Binding of Myomesin to Obscurin-Like-1 at the Muscle M-Band Provides a Strategy for Isoform-Specific Mechanical Protection.
Structure, 25, 2017
2KPL
DownloadVisualize
BU of 2kpl by Molmil
MAGI-1 PDZ1 / E6CT
Descriptor: Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1, Protein E6
Authors:Charbonnier, S, Nomine, Y, Ramirez, J, Luck, K, Stote, R.H, Trave, G, Kieffer, B, Atkinson, R.A.
Deposit date:2009-10-16
Release date:2010-10-27
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:The structural and dynamic response of MAGI-1 PDZ1 with non-canonical domain boundaries to binding of human papillomavirus (HPV) E6
J.Mol.Biol., 2011
2L09
DownloadVisualize
BU of 2l09 by Molmil
Solution NMR Structure of Protein asr4154 from Nostoc sp. PCC7120 Northeast Structural Genomics Consortium target ID NsR143
Descriptor: Asr4154 protein
Authors:Feldmann, E.A, Yang, Y.A, Ramelot, T.A, Cort, J.R, Janjua, H, Ciccosanti, C.A, Lee, D, Acton, T.B, Xiao, R.A, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG)
Deposit date:2010-06-30
Release date:2010-08-25
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR Solution Structure of asr4154 from Nostoc sp. PCC7120 Northeast Structural Genomics target ID Nsr143
To be Published
8V4X
DownloadVisualize
BU of 8v4x by Molmil
Structure of MALT1 in complex with an allosteric inhibitor
Descriptor: Inhibitor peptide, Mucosa-associated lymphoid tissue lymphoma translocation protein 1, N-{7-[(1S)-1-methoxyethyl]-2-methyl[1,3]thiazolo[5,4-b]pyridin-6-yl}-N'-[6-(2H-1,2,3-triazol-2-yl)-5-(trifluoromethyl)pyridin-3-yl]urea
Authors:Judge, R.A, Pappano, W.N.
Deposit date:2023-11-29
Release date:2024-05-01
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (2.486 Å)
Cite:Inhibition of MALT1 and BCL2 Induces Synergistic Antitumor Activity in Models of B-Cell Lymphoma.
Mol.Cancer Ther., 23, 2024

225158

PDB entries from 2024-09-18

PDB statisticsPDBj update infoContact PDBjnumon