4LQY

Crystal Structure of Human ENPP4 with AMP

Summary for 4LQY

Entry DOI	10.2210/pdb4lqy/pdb
Related	4LR0 4LR1 4LR2 4LR5
Descriptor	Bis(5'-adenosyl)-triphosphatase ENPP4, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	npp4, enpp4, phosphodiesterase, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Cell membrane ; Single-pass type I membrane protein : Q9Y6X5
Total number of polymer chains	1
Total formula weight	47454.81
Authors	Albright, R.A.,Braddock, D.T. (deposition date: 2013-07-19, release date: 2013-12-18, Last modification date: 2023-09-20)
Primary citation	Albright, R.A.,Ornstein, D.L.,Cao, W.,Chang, W.C.,Robert, D.,Tehan, M.,Hoyer, D.,Liu, L.,Stabach, P.,Yang, G.,De La Cruz, E.M.,Braddock, D.T. Molecular basis of purinergic signal metabolism by ectonucleotide pyrophosphatase/phosphodiesterases 4 and 1 and implications in stroke. J.Biol.Chem., 289:3294-3306, 2014 Cited by PubMed: 24338010 DOI: 10.1074/jbc.M113.505867 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.54 Å)

Structure validation