Author results

5VZV
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TRIM23 RING DOMAIN
Descriptor:E3 ubiquitin-protein ligase TRIM23, ZINC ION
Authors:Pornillos, O., Dawidziak, D.
Deposit date:2017-05-29
Release date:2017-08-09
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.812 Å)
Cite:Structure and catalytic activation of the TRIM23 RING E3 ubiquitin ligase.
Proteins, 85, 2017
5TSX
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HIV-1 CA HEXAMER WITH NUP153 PEPTIDE - P1 CRYSTAL FORM
Descriptor:HIV-1 CA protein, Nuclear pore complex protein Nup153, 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID
Authors:Skorupka, K., Ganser-Pornillos, B.K., Pornillos, O.
Deposit date:2016-10-31
Release date:2017-11-08
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:HIV-1 CA hexamer with NUP153 peptide - P1 crystal form
To Be Published
3H47
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X-RAY STRUCTURE OF HEXAMERIC HIV-1 CA
Descriptor:Capsid protein p24
Authors:Pornillos, O.
Deposit date:2009-04-18
Release date:2009-06-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray structures of the hexameric building block of the HIV capsid.
Cell(Cambridge,Mass.), 137, 2009
3MGE
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X-RAY STRUCTURE OF HEXAMERIC HIV-1 CA
Descriptor:Capsid protein p24, 1,2-ETHANEDIOL
Authors:Pornillos, O.
Deposit date:2010-04-05
Release date:2010-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Disulfide Bond Stabilization of the Hexameric Capsomer of Human Immunodeficiency Virus.
J.Mol.Biol., 401, 2010
5EIU
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MINI TRIM5 B-BOX 2 DIMER C2 CRYSTAL FORM
Descriptor:TRIM protein-E3 ligase Chimera, ZINC ION
Authors:Wagner, J.M., Doss, G., Pornillos, O.
Deposit date:2015-10-30
Release date:2016-06-15
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.908 Å)
Cite:Mechanism of B-box 2 domain-mediated higher-order assembly of the retroviral restriction factor TRIM5 alpha.
Elife, 5, 2016
6BHS
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HIV-1 CA HEXAMER IN COMPLEX WITH IP6, HEXAGONAL CRYSTAL FORM
Descriptor:Capsid protein p24, INOSITOL HEXAKISPHOSPHATE
Authors:Zadrozny, K., Wagner, J.M., Ganser-Pornillos, B.K., Pornillos, O.
Deposit date:2017-10-31
Release date:2018-08-01
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (1.984 Å)
Cite:Inositol phosphates are assembly co-factors for HIV-1.
Nature, 560, 2018
4QNB
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DISULFIDE STABILIZED HIV-1 CA HEXAMER IN COMPLEX WITH PHENYL-L-PHENYLALANINAMIDE INHIBITOR
Descriptor:CAPSID PROTEIN P24, N-METHYL-NALPHA-[(2-METHYL-1H-INDOL-3-YL)ACETYL]-N-PHENYL-L-PHENYLALANINAMIDE
Authors:Pornillos, O.
Deposit date:2014-06-17
Release date:2014-12-31
Last modified:2015-02-25
Method:X-RAY DIFFRACTION (1.996 Å)
Cite:Structural basis of HIV-1 capsid recognition by PF74 and CPSF6.
Proc.Natl.Acad.Sci.USA, 111, 2014
5TEO
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DIMER OF HIV-1 GAG CTD-SP1 FRAGMENT
Descriptor:HIV-1 Gag CTD-SP1
Authors:Pornillos, O., Wagner, J.M., Zadrozny, K.K., Ganser-Pornillos, B.K.
Deposit date:2016-09-22
Release date:2017-09-27
Method:X-RAY DIFFRACTION (2.046 Å)
Cite:To be published
To Be Published
5VZW
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TRIM23 RING DOMAIN IN COMPLEX WITH UBCH5-UB
Descriptor:Ubiquitin-conjugating enzyme E2 D2, Ubiquitin, E3 ubiquitin-protein ligase TRIM23, ...
Authors:Pornillos, O., Dawidziak, D.
Deposit date:2017-05-29
Release date:2017-08-09
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.278 Å)
Cite:Structure and catalytic activation of the TRIM23 RING E3 ubiquitin ligase.
Proteins, 85, 2017
5F7T
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TRIM5 B-BOX2 AND COILED-COIL CHIMERA
Descriptor:Tripartite motif-containing protein 5,Serine--tRNA ligase,Tripartite motif-containing protein 5, ZINC ION
Authors:Wagner, J.M., Doss, G., Pornillos, O.
Deposit date:2015-12-08
Release date:2016-06-15
Method:X-RAY DIFFRACTION (2.292 Å)
Cite:Mechanism of B-box 2 domain-mediated higher-order assembly of the retroviral restriction factor TRIM5 alpha.
Elife, 5, 2016
5VA4
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TRIM-CYCLOPHILIN A B-BOX 2 AND COILED-COIL CHIMERA
Descriptor:TRIM5/cyclophilin A V4 fusion protein, ZINC ION
Authors:Wagner, J.M., Ganser-Pornillos, B.K., Pornillos, O.W.
Deposit date:2017-03-24
Release date:2017-11-22
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.306 Å)
Cite:General Model for Retroviral Capsid Pattern Recognition by TRIM5 Proteins.
J. Virol., 92, 2018
5EYA
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TRIM25 RING DOMAIN IN COMPLEX WITH UBC13-UB CONJUGATE
Descriptor:Ubiquitin-conjugating enzyme E2 N, Tripartite motif-containing 25 variant, Polyubiquitin-B, ...
Authors:Pornillos, O., Sanchez, J.G.
Deposit date:2015-11-24
Release date:2016-08-17
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Mechanism of TRIM25 Catalytic Activation in the Antiviral RIG-I Pathway.
Cell Rep, 16, 2016
4XFX
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STRUCTURE OF THE NATIVE FULL-LENGTH HIV-1 CAPSID PROTEIN
Descriptor:HIV-1 capsid protein, IODIDE ION, CHLORIDE ION
Authors:Gres, A.T., Kirby, K.A., Sarafianos, S.G.
Deposit date:2014-12-29
Release date:2015-06-10
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:STRUCTURAL VIROLOGY. X-ray crystal structures of native HIV-1 capsid protein reveal conformational variability.
Science, 349, 2015
3P05
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X-RAY STRUCTURE OF PENTAMERIC HIV-1 CA
Descriptor:HIV-1 CA, IODIDE ION
Authors:Pornillos, O.
Deposit date:2010-09-27
Release date:2011-01-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Atomic-level modelling of the HIV capsid.
Nature, 469, 2011
5TSV
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HIV-1 CA HEXAMER WITH NUP153 PEPTIDE - R3 CRYSTAL FORM
Descriptor:HIV-1 CA protein, Nuclear pore complex protein Nup153, 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID
Authors:Skorupka, K., Ganser-Pornillos, B.K., Pornillos, O.
Deposit date:2016-10-31
Release date:2017-11-08
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:HIV-1 CA hexamer with NUP153 peptide - R3 crystal form
To Be Published
4LTB
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COILED-COIL DOMAIN OF TRIM25
Descriptor:Tripartite motif-containing 25 variant
Authors:Pornillos, O., Sanchez, J.G., Okreglicka, K.
Deposit date:2013-07-23
Release date:2014-02-05
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:The tripartite motif coiled-coil is an elongated antiparallel hairpin dimer.
Proc.Natl.Acad.Sci.USA, 111, 2014
4WYM
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STRUCTURAL BASIS OF HIV-1 CAPSID RECOGNITION BY CPSF6
Descriptor:Capsid protein p24, ISOFORM 2 OF CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 6
Authors:Battacharya, A., Taylor, A.B., Hart, P.J., Ivanov, D.N.
Deposit date:2014-11-17
Release date:2014-12-17
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of HIV-1 capsid recognition by PF74 and CPSF6.
Proc.Natl.Acad.Sci.USA, 111, 2014
5TUT
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UBCH5A-UB ISOPEPTIDE CONJUGATE
Descriptor:Ubiquitin-conjugating enzyme E2 D1, Ubiquitin
Authors:Sanchez, J.G., Wagner, J.M., Pornillos, O.
Deposit date:2016-11-07
Release date:2017-11-08
Method:X-RAY DIFFRACTION (2.604 Å)
Cite:UbcH5a-Ub isopeptide conjugate
To be Published
6BHT
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HIV-1 CA HEXAMER IN COMPLEX WITH IP6, ORTHORHOMBIC CRYSTAL FORM
Descriptor:Capsid protein p24, INOSITOL HEXAKISPHOSPHATE
Authors:Zadrozny, K., Wagner, J.M., Ganser-Pornillos, B.K., Pornillos, O.
Deposit date:2017-10-31
Release date:2018-08-01
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.689 Å)
Cite:Inositol phosphates are assembly co-factors for HIV-1.
Nature, 560, 2018
4XFZ
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STRUCTURE OF THE NATIVE FULL-LENGTH HIV-1 CAPSID PROTEIN IN COMPLEX WITH PF-3450074 (PF74)
Descriptor:HIV-1 capsid protein, IODIDE ION, CHLORIDE ION, ...
Authors:Gres, A.T., Kirby, K.A., Sarafianos, S.G.
Deposit date:2014-12-29
Release date:2015-06-10
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:STRUCTURAL VIROLOGY. X-ray crystal structures of native HIV-1 capsid protein reveal conformational variability.
Science, 349, 2015
3H4E
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X-RAY STRUCTURE OF HEXAMERIC HIV-1 CA
Descriptor:Capsid protein p24
Authors:Pornillos, O.
Deposit date:2009-04-19
Release date:2009-06-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.704 Å)
Cite:X-ray structures of the hexameric building block of the HIV capsid.
Cell(Cambridge,Mass.), 137, 2009
4XFY
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STRUCTURE OF THE NATIVE FULL-LENGTH DEHYDRATED HIV-1 CAPSID PROTEIN
Descriptor:HIV-1 capsid protein, CHLORIDE ION, PENTAETHYLENE GLYCOL
Authors:Gres, A.T., Kirby, K.A., Sarafianos, S.G.
Deposit date:2014-12-29
Release date:2015-06-10
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:STRUCTURAL VIROLOGY. X-ray crystal structures of native HIV-1 capsid protein reveal conformational variability.
Science, 349, 2015
6BHR
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HIV-1 IMMATURE CTD-SP1 HEXAMER IN COMPLEX WITH IP6
Descriptor:Capsid protein p24,Spacer peptide 1, INOSITOL HEXAKISPHOSPHATE
Authors:Zadrozny, K., Wagner, J.M., Ganser-Pornillos, B.K., Pornillos, O.
Deposit date:2017-10-31
Release date:2018-08-08
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.908 Å)
Cite:Inositol phosphates are assembly co-factors for HIV-1.
Nature, 560, 2018
5IEA
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TRIM5 B-BOX2 AND COILED-COIL CHIMERA
Descriptor:Tripartite motif-containing protein 5, Serine--tRNA ligase Chimera, ZINC ION
Authors:Wagner, J.M., Doss, G., Pornillos, O.
Deposit date:2016-02-25
Release date:2016-06-15
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.258 Å)
Cite:Mechanism of B-box 2 domain-mediated higher-order assembly of the retroviral restriction factor TRIM5 alpha.
Elife, 5, 2016
5I4T
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IMMATURE HEXAGONAL LATTICE OF HIV-1 GAG
Descriptor:CTD-SP1 fragment of HIV-1 Gag
Authors:Pornillos, O., Wagner, J.M., Zadrozny, K., Ganser-Pornillos, B.K.
Deposit date:2016-02-12
Release date:2016-07-27
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (3.273 Å)
Cite:Crystal structure of an HIV assembly and maturation switch.
Elife, 5, 2016
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