Author results

4DN3
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CRYSTAL STRUCTURE OF ANTI-MCP-1 ANTIBODY CNTO888
Descriptor:CNTO888 LIGHT CHAIN, CNTO888 HEAVY CHAIN
Authors:Obmolova, G., Teplyakov, A., Malia, T., Grygiel, T., Sweet, R., Snyder, L., Gilliland, G.
Deposit date:2012-02-08
Release date:2012-10-03
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for high selectivity of anti-CCL2 neutralizing antibody CNTO 888.
Mol.Immunol., 51, 2012
4DN4
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CNTO888 FAB AND MCP-1 MUTANT P8A
Descriptor:CNTO888 LIGHT CHAIN, CNTO888 HEAVY CHAIN, C-C motif chemokine 2, ...
Authors:Obmolova, G., Teplyakov, A., Malia, T., Grygiel, T., Sweet, R., Snyder, L., Gilliland, G.
Deposit date:2012-02-08
Release date:2012-10-03
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for high selectivity of anti-CCL2 neutralizing antibody CNTO 888.
Mol.Immunol., 51, 2012
1EWQ
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CRYSTAL STRUCTURE TAQ MUTS COMPLEXED WITH A HETERODUPLEX DNA AT 2.2 A RESOLUTION
Descriptor:DNA (5'-D(*GP*CP*GP*AP*CP*GP*CP*TP*AP*GP*CP*GP*TP*GP*CP*GP*GP*CP*TP*CP*GP*TP*C)-3'), DNA (5'-D(*GP*GP*AP*CP*GP*AP*GP*CP*CP*GP*CP*CP*GP*CP*TP*AP*GP*CP*GP*TP*CP*G)-3'), DNA MISMATCH REPAIR PROTEIN MUTS, ...
Authors:Obmolova, G., Ban, C., Hsieh, P., Yang, W.
Deposit date:2000-04-26
Release date:2000-10-23
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA.
Nature, 407, 2000
1EWR
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CRYSTAL STRUCTURE OF TAQ MUTS
Descriptor:DNA MISMATCH REPAIR PROTEIN MUTS
Authors:Obmolova, G., Ban, C., Hsieh, P., Yang, W.
Deposit date:2000-04-26
Release date:2000-10-23
Last modified:2018-06-27
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA.
Nature, 407, 2000
1JJV
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DEPHOSPHO-COA KINASE IN COMPLEX WITH ATP
Descriptor:DEPHOSPHO-COA KINASE, SULFATE ION, MERCURY (II) ION, ...
Authors:Obmolova, G., Teplyakov, A., Bonander, N., Eisenstein, E., Howard, A.J., Gilliland, G.L., Structure 2 Function Project (S2F)
Deposit date:2001-07-09
Release date:2002-05-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of dephospho-coenzyme A kinase from Haemophilus influenzae.
J.Struct.Biol., 136, 2001
1LQA
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TAS PROTEIN FROM ESCHERICHIA COLI IN COMPLEX WITH NADPH
Descriptor:Tas protein, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Obmolova, G., Teplyakov, A., Khil, P.P., Howard, A.J., Camerini-Otero, R.D., Gilliland, G.L., Structure 2 Function Project (S2F)
Deposit date:2002-05-09
Release date:2003-07-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.604 Å)
Cite:Crystal structure of the Escherichia coli Tas protein, an NADP(H)-dependent aldo-keto reductase
PROTEINS: STRUCT.,FUNCT.,GENET., 53, 2003
5TLJ
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COMPLEX BETWEEN HUMAN CD27 AND FAB FRAGMENTS OF ANTIBODIES M2177 AND M2191
Descriptor:M2177 LIGHT CHAIN, M2177 HEAVY CHAIN, M2191 LIGHT CHAIN, ...
Authors:Teplyakov, A., Obmolova, G., Malia, T., Gilliland, G.L.
Deposit date:2016-10-11
Release date:2017-02-08
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Epitope-dependent mechanisms of CD27 neutralization revealed by X-ray crystallography.
Mol. Immunol., 83, 2017
5TLK
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COMPLEX BETWEEN HUMAN CD27 AND FAB FRAGMENTS OF ANTIBODIES M2177 AND H2191
Descriptor:M2177 LIGHT CHAIN, M2177 HEAVY CHAIN, H2191 LIGHT CHAIN, ...
Authors:Teplyakov, A., Obmolova, G., Malia, T., Gilliland, G.L.
Deposit date:2016-10-11
Release date:2017-02-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Epitope-dependent mechanisms of CD27 neutralization revealed by X-ray crystallography.
Mol. Immunol., 83, 2017
1MOS
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ISOMERASE DOMAIN OF GLUCOSAMINE 6-PHOSPHATE SYNTHASE COMPLEXED WITH 2-AMINO-2-DEOXYGLUCITOL 6-PHOSPHATE
Descriptor:GLUCOSAMINE 6-PHOSPHATE SYNTHASE, SULFATE ION, SODIUM ION, ...
Authors:Teplyakov, A., Obmolova, G., Badet-Denisot, M.A., Badet, B.
Deposit date:1998-07-15
Release date:1999-07-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The mechanism of sugar phosphate isomerization by glucosamine 6-phosphate synthase.
Protein Sci., 8, 1999
5I15
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CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV1-69/IGKV1-39
Descriptor:FAB LIGHT CHAIN, FAB HEAVY CHAIN, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Teplyakov, A., Obmolova, G., Malia, T., Luo, J., Gilliland, G.
Deposit date:2016-02-05
Release date:2016-06-08
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural diversity in a human antibody germline library.
Mabs, 8, 2016
5I16
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CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV1-69/IGKV3-11
Descriptor:FAB LIGHT CHAIN, FAB HEAVY CHAIN, GLYCEROL, ...
Authors:Teplyakov, A., Obmolova, G., Malia, T., Luo, J., Gilliland, G.
Deposit date:2016-02-05
Release date:2016-06-08
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural diversity in a human antibody germline library.
Mabs, 8, 2016
5I17
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CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV1-69/IGKV3-20
Descriptor:FAB LIGHT CHAIN, FAB HEAVY CHAIN, SULFATE ION
Authors:Teplyakov, A., Obmolova, G., Malia, T., Luo, J., Gilliland, G.
Deposit date:2016-02-05
Release date:2016-06-08
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural diversity in a human antibody germline library.
Mabs, 8, 2016
5I18
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CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV1-69/IGKV4-1
Descriptor:FAB LIGHT CHAIN, FAB HEAVY CHAIN, GLYCEROL
Authors:Teplyakov, A., Obmolova, G., Malia, T., Luo, J., Gilliland, G.
Deposit date:2016-02-05
Release date:2016-02-24
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural diversity in a human antibody germline library.
Mabs, 8, 2016
5I19
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CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-23/IGKV1-39
Descriptor:FAB LIGHT CHAIN, FAB HEAVY CHAIN
Authors:Teplyakov, A., Obmolova, G., Malia, T., Luo, J., Gilliland, G.
Deposit date:2016-02-05
Release date:2016-06-08
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural diversity in a human antibody germline library.
Mabs, 8, 2016
5I1A
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CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-23/IGKV3-11
Descriptor:CNTO388 LIGHT CHAIN, CNTO388 HEAVY CHAIN, ACETATE ION, ...
Authors:Teplyakov, A., Obmolova, G., Malia, T., Luo, J., Gilliland, G.
Deposit date:2016-02-05
Release date:2016-06-08
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural diversity in a human antibody germline library.
Mabs, 8, 2016
5I1C
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CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-23/IGKV3-20
Descriptor:FAB LIGHT CHAIN, FAB HEAVY CHAIN, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Teplyakov, A., Obmolova, G., Malia, T., Luo, J., Gilliland, G.
Deposit date:2016-02-05
Release date:2016-06-08
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural diversity in a human antibody germline library.
Mabs, 8, 2016
5I1D
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CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-23/IGKV4-1
Descriptor:FAB LIGHT CHAIN, FAB HEAVY CHAIN, SULFATE ION
Authors:Teplyakov, A., Obmolova, G., Malia, T., Luo, J., Gilliland, G.
Deposit date:2016-02-05
Release date:2016-02-24
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural diversity in a human antibody germline library.
Mabs, 8, 2016
5I1E
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CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-53/IGKV1-39
Descriptor:FAB LIGHT CHAIN, FAB HEAVY CHAIN, SULFATE ION, ...
Authors:Teplyakov, A., Obmolova, G., Malia, T., Luo, J., Gilliland, G.
Deposit date:2016-02-05
Release date:2016-06-08
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural diversity in a human antibody germline library.
Mabs, 8, 2016
5I1G
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CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-53/IGKV3-11
Descriptor:FAB LIGHT CHAIN, FAB HEAVY CHAIN, SULFATE ION
Authors:Teplyakov, A., Obmolova, G., Malia, T., Luo, J., Gilliland, G.
Deposit date:2016-02-05
Release date:2016-06-08
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural diversity in a human antibody germline library.
Mabs, 8, 2016
5I1H
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CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-53/IGKV3-20
Descriptor:FAB LIGHT CHAIN, FAB HEAVY CHAIN, SULFATE ION
Authors:Teplyakov, A., Obmolova, G., Malia, T., Luo, J., Gilliland, G.
Deposit date:2016-02-05
Release date:2016-06-08
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (2.222 Å)
Cite:Structural diversity in a human antibody germline library.
Mabs, 8, 2016
5I1I
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CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-53/IGKV4-1
Descriptor:FAB LIGHT CHAIN, FAB HEAVY CHAIN
Authors:Teplyakov, A., Obmolova, G., Malia, T., Luo, J., Gilliland, G.
Deposit date:2016-02-05
Release date:2016-06-08
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural diversity in a human antibody germline library.
Mabs, 8, 2016
5I1J
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CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV5-51/IGKV3-11
Descriptor:FAB LIGHT CHAIN, FAB HEAVY CHAIN, GLYCEROL
Authors:Teplyakov, A., Obmolova, G., Malia, T., Luo, J., Gilliland, G.
Deposit date:2016-02-05
Release date:2016-06-08
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural diversity in a human antibody germline library.
Mabs, 8, 2016
5I1K
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CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV5-51/IGKV3-20
Descriptor:FAB LIGHT CHAIN, FAB HEAVY CHAIN, GLYCEROL, ...
Authors:Teplyakov, A., Obmolova, G., Malia, T., Luo, J., Gilliland, G.
Deposit date:2016-02-05
Release date:2016-06-08
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural diversity in a human antibody germline library.
Mabs, 8, 2016
5I1L
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CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV5-51/IGKV4-1
Descriptor:FAB LIGHT CHAIN, FAB HEAVY CHAIN, GLYCEROL
Authors:Teplyakov, A., Obmolova, G., Malia, T., Luo, J., Gilliland, G.
Deposit date:2016-02-05
Release date:2016-06-08
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural diversity in a human antibody germline library.
Mabs, 8, 2016
1PB0
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YCDX PROTEIN IN AUTOINHIBITED STATE
Descriptor:Hypothetical protein ycdX, ZINC ION, SULFATE ION, ...
Authors:Teplyakov, A., Obmolova, G., Khil, P.P., Camerini-Otero, R.D., Gilliland, G.L.
Deposit date:2003-05-14
Release date:2004-05-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Autoregulation of YcdX protein
To be Published