Author results

1UFW
  • Download 1ufw
  • View 1ufw
Molmil generated image of 1ufw
SOLUTION STRUCTURE OF RNP DOMAIN IN SYNAPTOJANIN 2
Descriptor:Synaptojanin 2
Authors:He, F., Muto, Y., Ushikoshi, R., Shirouzu, M., Terada, T., Kigawa, T., Inoue, M., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Hirota, H., Yoshida, M., Kobayashi, N., Tanaka, A., Osanai, T., Matsuo, Y., Ohara, O., Nagase, T., Kikuno, R., Nakayama, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-06-10
Release date:2003-12-10
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of RNP domain in Synaptojanin 2
To be Published
1UFX
  • Download 1ufx
  • View 1ufx
Molmil generated image of 1ufx
SOLUTION STRUCTURE OF THE THIRD PDZ DOMAIN OF HUMAN KIAA1526 PROTEIN
Descriptor:KIAA1526 protein
Authors:Tochio, N., Kobayashi, N., Koshiba, S., Kigawa, T., Inoue, M., Shirouzu, M., Terada, T., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Hirota, H., Yoshida, M., Tanaka, A., Osanai, T., Matsuo, Y., Ohara, O., Nagase, T., Kikuno, R., Nakayama, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-06-10
Release date:2003-12-10
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the third PDZ domain of human KIAA1526 protein
To be Published
1UG1
  • Download 1ug1
  • View 1ug1
Molmil generated image of 1ug1
SH3 DOMAIN OF HYPOTHETICAL PROTEIN BAA76854.1
Descriptor:KIAA1010 protein
Authors:Nagata, T., Muto, Y., Kamewari, Y., Shirouzu, M., Terada, T., Kigawa, T., Inoue, M., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Hirota, H., Yoshida, M., Kobayashi, N., Tanaka, A., Osanai, T., Matsuo, Y., Ohara, O., Nagase, T., Kikuno, R., Nakayama, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-06-11
Release date:2003-12-11
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR structure of SH3 domain of Hypothetical protein BAA76854.1
To be Published
1UGK
  • Download 1ugk
  • View 1ugk
Molmil generated image of 1ugk
SOLUTION STRUCTURE OF THE FIRST C2 DOMAIN OF SYNAPTOTAGMIN IV FROM HUMAN FETAL BRAIN (KIAA1342)
Descriptor:Synaptotagmin IV
Authors:Nagashima, T., Hayashi, F., Shirouzu, M., Terada, T., Kigawa, T., Inoue, M., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Hirota, H., Yoshida, M., Tanaka, A., Osanai, T., Matsuo, Y., Ohara, O., Nagase, T., Kikuno, R., Nakayama, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-06-16
Release date:2003-12-16
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the first C2 domain of synaptotagmin IV from human fetal brain (KIAA1342)
To be Published
1UGV
  • Download 1ugv
  • View 1ugv
Molmil generated image of 1ugv
SOLUTION STRUCTURE OF THE SH3 DOMAIN OF HUMAN OLYGOPHREIN-1 LIKE PROTEIN (KIAA0621)
Descriptor:Olygophrenin-1 like protein
Authors:Inoue, K., Hayashi, F., Shirouzu, M., Terada, T., Kigawa, T., Inoue, M., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Hirota, H., Yoshida, M., Tanaka, A., Osanai, T., Matsuo, Y., Ohara, O., Nagase, T., Kikuno, R., Nakayama, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-06-20
Release date:2003-12-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the SH3 domain of human olygophrein-1 like protein (KIAA0621)
To be Published
2D32
  • Download 2d32
  • View 2d32
Molmil generated image of 2d32
CRYSTAL STRUCTURE OF MICHAELIS COMPLEX OF GAMMA-GLUTAMYLCYSTEINE SYNTHETASE
Descriptor:Glutamate--cysteine ligase, MAGNESIUM ION, GLUTAMIC ACID, ...
Authors:Hibi, T., Nakayama, M., Nii, H., Kurokawa, Y., Katano, H., Oda, J.
Deposit date:2005-09-25
Release date:2006-11-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of efficient coupling peptide ligation and ATP hydrolysis by gamma-gluatamylcysteine synthetase
To be Published
2D33
  • Download 2d33
  • View 2d33
Molmil generated image of 2d33
CRYSTAL STRUCTURE OF GAMMA-GLUTAMYLCYSTEINE SYNTHETASE COMPLEXED WITH ALUMINUM FLUORIDE
Descriptor:Glutamate--cysteine ligase, MAGNESIUM ION, GLUTAMIC ACID, ...
Authors:Hibi, T., Nakayama, M., Nii, H., Kurokawa, Y., Katano, H., Oda, J.
Deposit date:2005-09-25
Release date:2006-11-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of efficient coupling between peptide ligation and ATP hydrolysis by gamma-gluatamylcysteine synthetase
To be Published
5H8V
  • Download 5h8v
  • View 5h8v
Molmil generated image of 5h8v
CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN MAIZE SULFITE REDUCTASE AND FERREDOXIN IN THE FORM-1 CRYSTAL
Descriptor:Sulfite reductase [ferredoxin], chloroplastic, IRON/SULFUR CLUSTER, ...
Authors:Kurisu, G., Nakayama, M., Hase, T.
Deposit date:2015-12-24
Release date:2016-04-13
Last modified:2016-08-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and mutational studies of an electron transfer complex of maize sulfite reductase and ferredoxin.
J.Biochem., 160, 2016
5H8Y
  • Download 5h8y
  • View 5h8y
Molmil generated image of 5h8y
CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN MAIZE SULFITE REDUCTASE AND FERREDOXIN IN THE FORM-2 CRYSTAL
Descriptor:Sulfite reductase [ferredoxin], chloroplastic, Ferredoxin-1, ...
Authors:Kurisu, G., Nakayama, M., Hase, T.
Deposit date:2015-12-25
Release date:2016-04-13
Last modified:2016-08-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and mutational studies of an electron transfer complex of maize sulfite reductase and ferredoxin.
J.Biochem., 160, 2016
5H92
  • Download 5h92
  • View 5h92
Molmil generated image of 5h92
CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN MAIZE SULFITE REDUCTASE AND FERREDOXIN IN THE FORM-3 CRYSTAL
Descriptor:Sulfite reductase [ferredoxin], chloroplastic, Ferredoxin-1, ...
Authors:Kurisu, G., Nakayama, M., Hase, T.
Deposit date:2015-12-25
Release date:2016-04-13
Last modified:2016-08-10
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Structural and mutational studies of an electron transfer complex of maize sulfite reductase and ferredoxin.
J.Biochem., 160, 2016
1IXD
  • Download 1ixd
  • View 1ixd
Molmil generated image of 1ixd
SOLUTION STRUCTURE OF THE CAP-GLY DOMAIN FROM HUMAN CYLINDROMATOSIS TOMOUR-SUPPRESSOR CYLD
Descriptor:Cylindromatosis tumour-suppressor CYLD
Authors:Saito, K., Koshiba, S., Kigawa, T., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2002-06-19
Release date:2002-12-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The CAP-Gly domain of CYLD associates with the proline-rich sequence in NEMO/IKKgamma
STRUCTURE, 12, 2004
5T8E
  • Download 5t8e
  • View 5t8e
Molmil generated image of 5t8e
SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS). PART II: OPTIMIZATION OF 4-(PYRROLIDIN-1-YL)BENZONITRILE DERIVATIVES
Descriptor:Androgen receptor, GLYCEROL, 2-chloro-4-[(2S,3S)-3-hydroxy-2-methylpyrrolidin-1-yl]-3-methylbenzonitrile
Authors:Wilson, K.P.
Deposit date:2016-09-07
Release date:2017-04-26
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs). Part II: Optimization of 4-(pyrrolidin-1-yl)benzonitrile derivatives.
Bioorg. Med. Chem. Lett., 27, 2017
5T8J
  • Download 5t8j
  • View 5t8j
Molmil generated image of 5t8j
SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS). PART II: OPTIMIZATION OF 4-(PYRROLIDIN-1-YL)BENZONITRILE DERIVATIVES
Descriptor:Androgen receptor, GLYCEROL, 2-fluoro-4-[(2S,3S)-3-hydroxy-2,3-dimethylpyrrolidin-1-yl]-3-methylbenzonitrile
Authors:Wilson, K.P.
Deposit date:2016-09-07
Release date:2017-04-26
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs). Part II: Optimization of 4-(pyrrolidin-1-yl)benzonitrile derivatives.
Bioorg. Med. Chem. Lett., 27, 2017
5V8Q
  • Download 5v8q
  • View 5v8q
Molmil generated image of 5v8q
SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS): PART III
Descriptor:Androgen receptor, GLYCEROL, 4-[(2S,3S)-2-ethyl-3-hydroxy-5-oxopyrrolidin-1-yl]-2-(trifluoromethyl)benzonitrile
Authors:Wilson, K.P.
Deposit date:2017-03-22
Release date:2017-05-24
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs) Part III: Discovery of 4-(5-oxopyrrolidine-1-yl)benzonitrile derivative 2f as a clinical candidate.
Bioorg. Med. Chem., 25, 2017
6B30
  • Download 6b30
  • View 6b30
Molmil generated image of 6b30
STRUCTURE OF RORGT IN COMPLEX WITH A NOVEL INVERSE AGONIST 1
Descriptor:Nuclear receptor ROR-gamma, N-[(1R)-1-(4-methoxyphenyl)-2-oxo-2-{[4-(trimethylsilyl)phenyl]amino}ethyl]-N-methyl-3-oxo-2,3-dihydro-1,2-oxazole-5-carboxamide
Authors:Skene, R.J., Hoffman, I.
Deposit date:2017-09-20
Release date:2018-01-03
Last modified:2018-01-10
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Discovery of orally efficacious ROR gamma t inverse agonists, part 1: Identification of novel phenylglycinamides as lead scaffolds.
Bioorg. Med. Chem., 26, 2018
6B31
  • Download 6b31
  • View 6b31
Molmil generated image of 6b31
STRUCTURE OF RORGT IN COMPLEX WITH A NOVEL INVERSE AGONIST 2
Descriptor:Nuclear receptor ROR-gamma, (3S)-N~1~-(3-chloro-4-cyanophenyl)-N~5~-(1,3-diethyl-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-6-yl)-3-methylpentanediamide
Authors:Skene, R.J., Hoffman, I.
Deposit date:2017-09-20
Release date:2018-08-01
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:Identification of novel quinazolinedione derivatives as ROR gamma t inverse agonist.
Bioorg. Med. Chem., 26, 2018
6DFQ
  • Download 6dfq
  • View 6dfq
Molmil generated image of 6dfq
MOUSE DIABETOGENIC TCR I.29
Descriptor:TCR alpha chain, TCR beta chain, CALCIUM ION, ...
Authors:Wang, Y., Dai, S.
Deposit date:2018-05-15
Release date:2019-04-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes.
Sci Immunol, 4, 2019
6DFS
  • Download 6dfs
  • View 6dfs
Molmil generated image of 6dfs
MOUSE TCR I.29 IN COMPLEX WITH IAG7-P8E9E6SS
Descriptor:mouse TCR alpha chain, mouse TCR beta chain, H-2 class II histocompatibility antigen, ...
Authors:Wang, Y., Dai, S.
Deposit date:2018-05-15
Release date:2019-04-17
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes.
Sci Immunol, 4, 2019
6DFV
  • Download 6dfv
  • View 6dfv
Molmil generated image of 6dfv
MOUSE DIABETOGENIC TCR 8F10
Descriptor:TCR alpha chain, TCR beta chain, 1,2-ETHANEDIOL
Authors:Wang, Y., Dai, S.
Deposit date:2018-05-15
Release date:2019-04-17
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes.
Sci Immunol, 4, 2019
6DFW
  • Download 6dfw
  • View 6dfw
Molmil generated image of 6dfw
TCR 8F10 IN COMPLEX WITH IAG7-P8G9E
Descriptor:H-2 class II histocompatibility antigen, A-D alpha chain, H2-Ab1 protein, ...
Authors:Wang, Y., Dai, S.
Deposit date:2018-05-15
Release date:2019-04-17
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes.
Sci Immunol, 4, 2019
6DFX
  • Download 6dfx
  • View 6dfx
Molmil generated image of 6dfx
HUMAN DIABETOGENIC TCR T1D3 IN COMPLEX WITH DQ8-P8E9E PEPTIDE
Descriptor:MHC class II HLA-DQ-alpha chain, MHC class II antigen, T1D3 alpha chain, ...
Authors:Wang, Y., Dai, S.
Deposit date:2018-05-15
Release date:2019-04-17
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes.
Sci Immunol, 4, 2019