Author results

2OSB
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CRYSTAL STRUCTURE OF A THERMOSTABLE MUTANT OF BACILLUS SUBTILIS ADENYLATE KINASE (Q16L/Q199R/)
分子名称:Adenylate kinase, ZINC ION, MAGNESIUM ION, ...
著者Myers, J., Counago, R., Wilson, C.J., Wu, G., Shamoo, Y.
登録日2007-02-05
公開日2008-01-15
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of a thermostable mutant of Bacillus subtilis Adenylate Kinase (Q16L/Q199R/)
To be Published
2OC8
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STRUCTURE OF HEPATITIS C VIRAL NS3 PROTEASE DOMAIN COMPLEXED WITH NS4A PEPTIDE AND KETOAMIDE SCH503034
分子名称:Hepatitis C virus, ZINC ION, BETA-MERCAPTOETHANOL, ...
著者Prongay, A.J., Guo, Z., Yao, N., Fischmann, T., Strickland, C., Myers, J., Weber, P.C., Malcolm, B., Beyer, B.M., Ingram, R., Pichardo, J., Hong, Z., Prosise, W.W., Ramanathan, L., Taremi, S.S., Yarosh-Tomaine, T., Zhang, R., Senior, M., Yang, R.S., Arasappan, A., Bennett, F., Bogen, S.L., Chen, K., Jao, E., Liu, Y.T., Lovey, R.G., Saksena, A.K., Venkatraman, S., Girijavallabhan, V., Njoroge, F.G., Madison, V.
登録日2006-12-20
公開日2007-07-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Discovery of the HCV NS3/4A protease inhibitor (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3- [2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (Sch 503034) II. Key steps in structure-based optimization.
J.Med.Chem., 50, 2007
2ORI
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CRYSTAL STRUCTURE OF A THERMOSTABLE MUTANT OF BACILLUS SUBTILIS ADENYLATE KINASE (A193V/Q199R/)
分子名称:Adenylate kinase, ZINC ION, MAGNESIUM ION, ...
著者Counago, R., Shamoo, Y., Wilson, C.J., Wu, G., Myers, J.
登録日2007-02-02
公開日2008-01-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of a thermostable mutant of Bacillus subtilis Adenylate Kinase (A193V/Q199R/)
To be Published
2P3S
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CRYSTAL STRUCTURE OF A THERMOSTABLE MUTANT OF BACILLUS SUBTILIS ADENYLATE KINASE (G214R/Q199R)
分子名称:Adenylate kinase, ZINC ION, MAGNESIUM ION, ...
著者Counago, R., Wilson, C.J., Myers, J., Wu, G., Shamoo, Y.
登録日2007-03-09
公開日2008-01-22
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of a thermostable mutant of Bacillus subtilis Adenylate Kinase (G214R/Q199R)
To be Published
2QAJ
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CRYSTAL STRUCTURE OF A THERMOSTABLE MUTANT OF BACILLUS SUBTILIS ADENYLATE KINASE (Q199R/G213E)
分子名称:Adenylate kinase, ZINC ION, MAGNESIUM ION, ...
著者Counago, R., Wilson, C.J., Myers, J., Wu, G., Shamoo, Y.
登録日2007-06-15
公開日2008-04-29
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of a thermostable mutant of Bacillus subtilis Adenylate Kinase (Q199R/G213E)
To be Published
5U6Y
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PSEUDO-ATOMIC MODEL OF THE CAMKIIA HOLOENZYME.
分子名称:Calcium/calmodulin-dependent protein kinase type II subunit alpha
著者Myers, J., Reichow, S.L.
登録日2016-12-09
公開日2017-06-21
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (20 Å)
主引用文献The CaMKII holoenzyme structure in activation-competent conformations.
Nat Commun, 8, 2017
3HZG
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS THYMIDYLATE SYNTHASE X BOUND WITH FAD
分子名称:Thymidylate synthase thyX, PHOSPHATE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Staker, B.L., Rathod, P., Hunter, J., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2009-06-23
公開日2009-07-07
最終更新日2015-04-22
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3U0B
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CRYSTAL STRUCTURE OF AN OXIDOREDUCTASE FROM MYCOBACTERIUM SMEGMATIS
分子名称:Oxidoreductase, short chain dehydrogenase/reductase family protein, SODIUM ION
著者Arakaki, T.L., Staker, B.L., Clifton, M.C., Abendroth, J., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-09-28
公開日2011-10-05
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
4EYE
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CRYSTAL STRUCTURE OF A PROBABLE OXIDOREDUCTASE FROM MYCOBACTERIUM ABSCESSUS SOLVED BY IODIDE ION SAD
分子名称:Probable oxidoreductase, (4S)-2-METHYL-2,4-PENTANEDIOL, IODIDE ION
著者Edwards, T.E., Abendroth, J., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-05-01
公開日2012-05-09
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
2O8M
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CRYSTAL STRUCTURE OF THE S139A MUTANT OF HEPATITIS C VIRUS NS3/4A PROTEASE
分子名称:Protease, ZINC ION, SODIUM ION
著者Fischmann, T.O., Prongay, A.J., Madison, V.M., Yao, N.
登録日2006-12-12
公開日2007-10-09
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery of the HCV NS3/4A protease inhibitor (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3- [2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (Sch 503034) II. Key steps in structure-based optimization
J.Med.Chem., 50, 2007
3GVC
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CRYSTAL STRUCTURE OF PROBABLE SHORT-CHAIN DEHYDROGENASE-REDUCTASE FROM MYCOBACTERIUM TUBERCULOSIS
分子名称:Probable short-chain type dehydrogenase/reductase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2009-03-30
公開日2009-04-07
最終更新日2015-04-22
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3GVG
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CRYSTAL STRUCTURE OF TRIOSEPHOSPHATE ISOMERASE FROM MYCOBACTERIUM TUBERCULOSIS
分子名称:Triosephosphate isomerase, GLYCEROL
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2009-03-31
公開日2009-04-14
最終更新日2015-04-22
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3GWC
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS THYMIDYLATE SYNTHASE X BOUND TO FDUMP AND FAD
分子名称:Thymidylate synthase thyX, FLAVIN-ADENINE DINUCLEOTIDE, 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2009-03-31
公開日2009-04-28
最終更新日2015-04-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3H7F
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CRYSTAL STRUCTURE OF SERINE HYDROXYMETHYLTRANSFERASE FROM MYCOBACTERIUM TUBERCULOSIS
分子名称:Serine hydroxymethyltransferase 1, MAGNESIUM ION
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2009-04-24
公開日2009-05-05
最終更新日2015-04-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3H81
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CRYSTAL STRUCTURE OF ENOYL-COA HYDRATASE FROM MYCOBACTERIUM TUBERCULOSIS
分子名称:enoyl-CoA hydratase echA8, GLYCEROL, CALCIUM ION
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2009-04-28
公開日2009-05-12
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3HE2
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CRYSTAL STRUCTURE OF ENOYL-COA HYDRATASE FROM MYCOBACTERIUM TUBERCULOSIS
分子名称:enoyl-CoA hydratase echA6, TRIETHYLENE GLYCOL
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2009-05-07
公開日2009-06-09
最終更新日2015-04-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3HWI
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CRYSTAL STRUCTURE OF PROBABLE THIOSULFATE SULFURTRANSFERASE CYSA2 (RHODANESE-LIKE PROTEIN) FROM MYCOBACTERIUM TUBERCULOSIS
分子名称:Thiosulfate sulfurtransferase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2009-06-17
公開日2009-06-30
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3HWK
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CRYSTAL STRUCTURE OF METHYLCITRATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS
分子名称:Methylcitrate synthase, SUCCINIC ACID
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2009-06-17
公開日2009-06-30
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3ICO
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CRYSTAL STRUCTURE OF 6-PHOSPHOGLUCONOLACTONASE FROM MYCOBACTERIUM TUBERCULOSIS
分子名称:6-phosphogluconolactonase, SULFATE ION
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2009-07-17
公開日2009-07-28
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3KHP
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CRYSTAL STRUCTURE OF A POSSIBLE DEHYDROGENASE FROM MYCOBACTERIUM TUBERCULOSIS AT 2.3A RESOLUTION
分子名称:MaoC family protein, CHLORIDE ION, L(+)-TARTARIC ACID
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2009-10-30
公開日2009-12-01
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3LLS
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CRYSTAL STRUCTURE OF 3-KETOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE FROM MYCOBACTERIUM TUBERCULOSIS
分子名称:3-ketoacyl-(Acyl-carrier-protein) reductase, SULFATE ION, 1,2-ETHANEDIOL
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2010-01-29
公開日2010-02-16
最終更新日2015-04-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3MOY
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CRYSTAL STRUCTURE OF PROBABLE ENOYL-COA HYDRATASE FROM MYCOBACTERIUM SMEGMATIS
分子名称:Probable enoyl-CoA hydratase, SULFATE ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2010-04-23
公開日2010-05-12
最終更新日2015-04-15
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3MPZ
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CRYSTAL STRUCTURE OF CYTIDINE DEAMINASE FROM MYCOBACTERIUM SMEGMATIS
分子名称:Cytidine deaminase, ZINC ION
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2010-04-27
公開日2010-05-19
最終更新日2015-04-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3MYB
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CRYSTAL STRUCTURE OF ENOYL-COA HYDRATASE MYCOBACTERIUM SMEGMATIS
分子名称:Enoyl-CoA hydratase, GLYCEROL
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2010-05-10
公開日2010-06-09
最終更新日2015-04-22
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3NDN
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CRYSTAL STRUCTURE OF O-SUCCINYLHOMOSERINE SULFHYDRYLASE FROM MYCOBACTERIUM TUBERCULOSIS COVALENTLY BOUND TO PYRIDOXAL-5-PHOSPHATE
分子名称:O-succinylhomoserine sulfhydrylase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2010-06-07
公開日2010-06-16
最終更新日2015-04-22
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015