3MNF
| Crystal structure of PAC2 family protein from Streptomyces avermitilis MA | Descriptor: | CHLORIDE ION, PAC2 family protein | Authors: | Chang, C, Hatzos, C, Morgan, T, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2010-04-21 | Release date: | 2010-05-05 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.97 Å) | Cite: | Crystal structure of PAC2 family protein from Streptomyces avermitilis MA To be Published
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2ERB
| AgamOBP1, and odorant binding protein from Anopheles gambiae complexed with PEG | Descriptor: | 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL, MAGNESIUM ION, odorant binding protein | Authors: | Wogulis, M, Morgan, T, Ishida, Y, Leal, W.S, Wilson, D.K. | Deposit date: | 2005-10-24 | Release date: | 2005-12-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The crystal structure of an odorant binding protein from Anopheles gambiae: Evidence for a common ligand release mechanism. Biochem.Biophys.Res.Commun., 339, 2006
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3KKC
| The crystal structure OF TetR transcriptional regulator from Streptococcus agalactiae 2603V | Descriptor: | IMIDAZOLE, NICKEL (II) ION, TetR family Transcriptional regulator | Authors: | Tan, K, Hatzos, C, Morgan, T, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2009-11-05 | Release date: | 2009-11-17 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The crystal structure OF TetR transcriptional regulator from Streptococcus agalactiae 2603V To be Published
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6OCZ
| Crystal Structure of Mycobacterium tuberculosis Proteasome in Complex with Phenylimidazole-based Inhibitor A86 | Descriptor: | CITRIC ACID, DIMETHYLFORMAMIDE, N-{(2S)-1-({(2S)-1-[(2,4-difluorobenzyl)amino]-1-oxopropan-2-yl}amino)-1,4-dioxo-4-[(2R)-2-phenylpyrrolidin-1-yl]butan-2-yl}-5-methyl-1,2-oxazole-3-carboxamide (non-preferred name), ... | Authors: | Hsu, H.C, Li, H. | Deposit date: | 2019-03-25 | Release date: | 2019-10-09 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Selective Phenylimidazole-Based Inhibitors of theMycobacterium tuberculosisProteasome. J.Med.Chem., 62, 2019
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6ODE
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6OCW
| Crystal Structure of Mycobacterium tuberculosis Proteasome in Complex with Phenylimidazole-based Inhibitor A85 | Descriptor: | CITRIC ACID, DIMETHYLFORMAMIDE, N-{(2S)-1-({(2S)-1-[(2,4-difluorobenzyl)amino]-1-oxopropan-2-yl}amino)-4-[(2S)-2-methylpiperidin-1-yl]-1,4-dioxobutan-2-yl}-5-methyl-1,2-oxazole-3-carboxamide (non-preferred name), ... | Authors: | Hsu, H.C, Li, H. | Deposit date: | 2019-03-25 | Release date: | 2019-10-09 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Selective Phenylimidazole-Based Inhibitors of theMycobacterium tuberculosisProteasome. J.Med.Chem., 62, 2019
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6RQJ
| Structure of human complement C5 complexed with tick inhibitors OmCI, RaCI1 and CirpT1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5, Complement inhibitor, ... | Authors: | Reichhardt, M.P, Johnson, S, Lea, S.M. | Deposit date: | 2019-05-15 | Release date: | 2020-01-08 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | An inhibitor of complement C5 provides structural insights into activation. Proc.Natl.Acad.Sci.USA, 117, 2020
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6RPT
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3DPD
| Achieving multi-isoform PI3K inhibition in a series of substituted 3,4-Dihydro-2H-benzo[1,4]oxazines | Descriptor: | 5,5-dimethyl-2-morpholin-4-yl-5,6-dihydro-1,3-benzothiazol-7(4H)-one, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Authors: | Ceska, T.A. | Deposit date: | 2008-07-08 | Release date: | 2008-08-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Achieving multi-isoform PI3K inhibition in a series of substituted 3,4-dihydro-2H-benzo[1,4]oxazines Bioorg.Med.Chem.Lett., 18, 2008
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3CGO
| IRAK-4 Inhibitors (Part II)- A structure based assessment of imidazo[1,2 a]pyridine binding | Descriptor: | 2-{4-[(4-imidazo[1,2-a]pyridin-3-ylpyrimidin-2-yl)amino]piperidin-1-yl}-N-methylacetamide, Mitogen-activated protein kinase 10 | Authors: | Ceska, T.A, Platt, A, Fortunato, M, Dickson, K.M, Beevers, R. | Deposit date: | 2008-03-06 | Release date: | 2008-06-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | IRAK-4 inhibitors. Part II: A structure-based assessment of imidazo[1,2-a]pyridine binding Bioorg.Med.Chem.Lett., 18, 2008
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3CGF
| IRAK-4 Inhibitors (Part II)- A structure based assessment of imidazo[1,2 a]pyridine binding | Descriptor: | Mitogen-activated protein kinase 10, N-cyclohexyl-4-imidazo[1,2-a]pyridin-3-yl-N-methylpyrimidin-2-amine | Authors: | Ceska, T.A, Platt, A, Fortunato, M, Dickson, K.M, Buckley, G. | Deposit date: | 2008-03-05 | Release date: | 2008-06-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | IRAK-4 inhibitors. Part II: A structure-based assessment of imidazo[1,2-a]pyridine binding Bioorg.Med.Chem.Lett., 18, 2008
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