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2BE6
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BU of 2be6 by Molmil
2.0 A crystal structure of the CaV1.2 IQ domain-Ca/CaM complex
Descriptor: CALCIUM ION, Calmodulin 2, NICKEL (II) ION, ...
Authors:Van Petegem, F, Chatelain, F.C, Minor Jr, D.L.
Deposit date:2005-10-23
Release date:2005-11-15
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Insights into voltage-gated calcium channel regulation from the structure of the Ca(V)1.2 IQ domain-Ca(2+)/calmodulin complex
Nat.Struct.Mol.Biol., 12, 2005
2I2R
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BU of 2i2r by Molmil
Crystal structure of the KChIP1/Kv4.3 T1 complex
Descriptor: CALCIUM ION, Kv channel-interacting protein 1, Potassium voltage-gated channel subfamily D member 3, ...
Authors:Findeisen, F, Pioletti, M, Minor Jr, D.L.
Deposit date:2006-08-16
Release date:2006-10-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Three-dimensional structure of the KChIP1-Kv4.3 T1 complex reveals a cross-shaped octamer
Nat.Struct.Mol.Biol., 13, 2006
1N0R
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BU of 1n0r by Molmil
4ANK: A designed ankyrin repeat protein with four identical consensus repeats
Descriptor: 4 ankyrin repeats, BROMIDE ION
Authors:Mosavi, L.K, Minor Jr, D.L, Peng, Z.-Y.
Deposit date:2002-10-14
Release date:2003-01-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Consensus-derived structural determinants of the ankyrin repeat motif.
Proc.Natl.Acad.Sci.USA, 99, 2002
1N0Q
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BU of 1n0q by Molmil
3ANK: A designed ankyrin repeat protein with three identical consensus repeats
Descriptor: 3 ankyrin repeats, trifluoroacetic acid
Authors:Mosavi, L.K, Minor Jr, D.L, Peng, Z.-Y.
Deposit date:2002-10-14
Release date:2003-01-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:Consensus-derived structural determinants of the ankyrin repeat motif.
Proc.Natl.Acad.Sci.USA, 99, 2002
1DSX
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BU of 1dsx by Molmil
KV1.2 T1 DOMAIN, RESIDUES 33-119, T46V MUTANT
Descriptor: PROTEIN (KV1.2 VOLTAGE-GATED POTASSIUM CHANNEL)
Authors:Minor Jr, D.L, Lin, Y.-F, Mobley, B.C, Avelar, A, Jan, Y.N, Jan, L.Y, Berger, J.M.
Deposit date:2000-01-10
Release date:2000-09-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The polar T1 interface is linked to conformational changes that open the voltage-gated potassium channel.
Cell(Cambridge,Mass.), 102, 2000
1QDV
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BU of 1qdv by Molmil
N-TERMINAL DOMAIN, VOLTAGE-GATED POTASSIUM CHANNEL KV1.2 RESIDUES 33-131
Descriptor: KV1.2 VOLTAGE-GATED POTASSIUM CHANNEL
Authors:Minor Jr, D.L, Lin, Y.-F, Mobley, B.C, Yu, M, Jan, Y.N, Jan, L.Y, Berger, J.M.
Deposit date:1999-07-10
Release date:2000-09-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The polar T1 interface is linked to conformational changes that open the voltage-gated potassium channel.
Cell(Cambridge,Mass.), 102, 2000
1QDW
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BU of 1qdw by Molmil
N-TERMINAL DOMAIN, VOLTAGE-GATED POTASSIUM CHANNEL KV1.2 RESIDUES 33-119
Descriptor: KV1.2 VOLTAGE-GATED POTASSIUM CHANNEL
Authors:Minor Jr, D.L, Lin, Y.-F, Mobley, B.C, Avelar, A, Jan, Y.N, Jan, L.Y, Berger, J.M.
Deposit date:1999-07-10
Release date:2000-09-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The polar T1 interface is linked to conformational changes that open the voltage-gated potassium channel.
Cell(Cambridge,Mass.), 102, 2000
6W7B
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BU of 6w7b by Molmil
K2P2.1 (TREK-1), 0 mM K+
Descriptor: CADMIUM ION, DECANE, DODECANE, ...
Authors:Lolicato, M, Minor, D.L.
Deposit date:2020-03-19
Release date:2021-01-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.88 Å)
Cite:K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
6W84
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BU of 6w84 by Molmil
K2P2.1 (TREK-1), 200 mM K+
Descriptor: CADMIUM ION, DODECANE, N-OCTANE, ...
Authors:Lolicato, M, Minor, D.L.
Deposit date:2020-03-20
Release date:2021-01-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
6W8A
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BU of 6w8a by Molmil
K2P2.1 (TREK-1):ML335 complex, 10 mM K+
Descriptor: CADMIUM ION, DODECANE, HEXADECANE, ...
Authors:Lolicato, M, Minor, D.L.
Deposit date:2020-03-20
Release date:2021-01-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.002 Å)
Cite:K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
6W8F
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BU of 6w8f by Molmil
K2P2.1 (TREK-1):ML335 complex, 0 mM K+
Descriptor: CADMIUM ION, DODECANE, HEXADECANE, ...
Authors:Lolicato, M, Minor, D.L.
Deposit date:2020-03-20
Release date:2021-01-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
6W7D
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BU of 6w7d by Molmil
K2P2.1 (TREK-1), 10 mM K+
Descriptor: CADMIUM ION, DODECANE, HEXADECANE, ...
Authors:Lolicato, M, Minor, D.L.
Deposit date:2020-03-19
Release date:2021-01-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
8D6G
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BU of 8d6g by Molmil
Nanorana parkeri saxiphilin
Descriptor: PENTAETHYLENE GLYCOL, Saxiphilin
Authors:Zakrzewska, S, Chen, Z, Minor, D.L.
Deposit date:2022-06-06
Release date:2022-11-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family.
Proc.Natl.Acad.Sci.USA, 119, 2022
8D6T
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BU of 8d6t by Molmil
Rana catesbeiana saxiphilin mutant - Y558I:STX (co-crystal)
Descriptor: CACODYLATE ION, Saxiphilin, [(3aS,4R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,9,10-tetrahydro-3H,8H-pyrrolo[1,2-c]purin-4-yl]methyl carbamate
Authors:Chen, Z, Zakrzewska, S, Minor, D.L.
Deposit date:2022-06-06
Release date:2022-11-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family.
Proc.Natl.Acad.Sci.USA, 119, 2022
8D6O
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BU of 8d6o by Molmil
Nanorana parkeri saxiphilin:F-STX (soaked)
Descriptor: (2P)-4-({6-[({[(3aS,4R,7R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,9,10-tetrahydro-3H,8H-pyrrolo[1,2-c]purin-4-yl]methoxy}carbonyl)amino]hexyl}carbamoyl)-2-{[4aP,9(9a)P]-6-hydroxy-3-oxo-3H-xanthen-9-yl}benzoic acid, PENTAETHYLENE GLYCOL, Saxiphilin
Authors:Zakrzewska, S, Chen, Z, Minor, D.L.
Deposit date:2022-06-06
Release date:2022-11-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family.
Proc.Natl.Acad.Sci.USA, 119, 2022
8D6P
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BU of 8d6p by Molmil
Rana catesbeiana saxiphilin mutant - Y558A
Descriptor: Saxiphilin
Authors:Chen, Z, Zakrzewska, S, Minor, D.L.
Deposit date:2022-06-06
Release date:2022-11-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family.
Proc.Natl.Acad.Sci.USA, 119, 2022
8D6Q
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BU of 8d6q by Molmil
Rana catesbeiana saxiphilin mutant - Y558I
Descriptor: Saxiphilin
Authors:Chen, Z, Zakrzewska, S, Minor, D.L.
Deposit date:2022-06-06
Release date:2022-11-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family.
Proc.Natl.Acad.Sci.USA, 119, 2022
8D6S
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BU of 8d6s by Molmil
Rana catesbeiana saxiphilin mutant - Y558A:STX (co-crystal)
Descriptor: Saxiphilin, [(3aS,4R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,9,10-tetrahydro-3H,8H-pyrrolo[1,2-c]purin-4-yl]methyl carbamate
Authors:Chen, Z, Zakrzewska, S, Minor, D.L.
Deposit date:2022-06-06
Release date:2022-11-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family.
Proc.Natl.Acad.Sci.USA, 119, 2022
8D6M
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BU of 8d6m by Molmil
Nanorana parkeri saxiphilin:STX (co-crystal)
Descriptor: PENTAETHYLENE GLYCOL, Saxiphilin, [(3aS,4R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,9,10-tetrahydro-3H,8H-pyrrolo[1,2-c]purin-4-yl]methyl carbamate
Authors:Zakrzewska, S, Chen, Z, Minor, D.L.
Deposit date:2022-06-06
Release date:2022-11-02
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family.
Proc.Natl.Acad.Sci.USA, 119, 2022
8D6U
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BU of 8d6u by Molmil
Rana catesbeiana saxiphilin:F-STX (soaked)
Descriptor: (2P)-4-({6-[({[(3aS,4R,7R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,9,10-tetrahydro-3H,8H-pyrrolo[1,2-c]purin-4-yl]methoxy}carbonyl)amino]hexyl}carbamoyl)-2-{[4aP,9(9a)P]-6-hydroxy-3-oxo-3H-xanthen-9-yl}benzoic acid, Saxiphilin
Authors:Chen, Z, Zakrzewska, S, Minor, D.L.
Deposit date:2022-06-06
Release date:2022-11-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family.
Proc.Natl.Acad.Sci.USA, 119, 2022
8DAM
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BU of 8dam by Molmil
nbF3:nbE8:CaV beta subunit 1b complex
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Nanobody E8, SULFATE ION, ...
Authors:Nirwan, N, Minor, D.L.
Deposit date:2022-06-13
Release date:2022-12-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Selective posttranslational inhibition of Ca V beta 1 -associated voltage-dependent calcium channels with a functionalized nanobody.
Nat Commun, 13, 2022
8E0E
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BU of 8e0e by Molmil
nbF3:CaV beta subunit 2a complex
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, GLYCEROL, ...
Authors:Nirwan, N, Minor, D.L.
Deposit date:2022-08-09
Release date:2023-01-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Selective posttranslational inhibition of Ca V beta 1 -associated voltage-dependent calcium channels with a functionalized nanobody.
Nat Commun, 13, 2022
7PG8
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BU of 7pg8 by Molmil
NaV_Ae1/Sp1CTD_pore-ANT05 complex
Descriptor: ANT05 H12 fab fragment, heavy chain, light chain, ...
Authors:Lolicato, M, Arrigoni, C.
Deposit date:2021-08-13
Release date:2022-06-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Nat.Struct.Mol.Biol., 29, 2022
7PGF
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BU of 7pgf by Molmil
Calcium-selective Sp1 channel pore domain only
Descriptor: Ion transporter
Authors:Lolicato, M, Arrigoni, C.
Deposit date:2021-08-13
Release date:2022-06-08
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Nat.Struct.Mol.Biol., 29, 2022
7PGG
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BU of 7pgg by Molmil
NaVAb1p detergent (DM)
Descriptor: 2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}ethyl heptadecanoate, Ion transport protein
Authors:Lolicato, M, Arrigoni, C.
Deposit date:2021-08-13
Release date:2022-06-15
Last modified:2022-06-29
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Nat.Struct.Mol.Biol., 29, 2022

 

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