8D6M

Nanorana parkeri saxiphilin:STX (co-crystal)

Summary for 8D6M

Entry DOI	10.2210/pdb8d6m/pdb
Descriptor	Saxiphilin, PENTAETHYLENE GLYCOL, [(3aS,4R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,9,10-tetrahydro-3H,8H-pyrrolo[1,2-c]purin-4-yl]methyl carbamate, ... (4 entities in total)
Functional Keywords	saxiphilin, toxin resistance, saxitoxin, antitoxin
Biological source	Nanorana parkeri
Total number of polymer chains	1
Total formula weight	95241.21
Authors	Zakrzewska, S.,Chen, Z.,Minor, D.L. (deposition date: 2022-06-06, release date: 2022-11-02, Last modification date: 2024-03-27)
Primary citation	Chen, Z.,Zakrzewska, S.,Hajare, H.S.,Alvarez-Buylla, A.,Abderemane-Ali, F.,Bogan, M.,Ramirez, D.,O'Connell, L.A.,Du Bois, J.,Minor Jr., D.L. Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family. Proc.Natl.Acad.Sci.USA, 119:e2210114119-e2210114119, 2022 Cited by PubMed: 36279441 DOI: 10.1073/pnas.2210114119 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation