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1GVN
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BU of 1gvn by Molmil
Crystal Structure of the Plasmid Maintenance System epsilon/zeta: Meachnism of toxin inactivation and toxin function
Descriptor: EPSILON, SULFATE ION, ZETA
Authors:Meinhart, A, Alonso, J.C, Straeter, N, Saenger, W.
Deposit date:2002-02-19
Release date:2003-01-29
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structure of the Plasmid Maintenance System Epsilon /Zeta : Functional Mechanism of Toxin Zeta and Inactivation by Epsilon 2 Zeta 2 Complex Formation
Proc.Natl.Acad.Sci.USA, 100, 2003
1Q1H
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BU of 1q1h by Molmil
An extended winged helix domain in general transcription factor E/IIE alpha
Descriptor: Transcription Factor E
Authors:Meinhart, A, Blobel, J, Cramer, P.
Deposit date:2003-07-21
Release date:2003-12-09
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:An Extended Winged Helix Domain in General Transcription Factor E/IIE alpha
J.Biol.Chem., 278, 2003
1SZA
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BU of 1sza by Molmil
The RNA polymerase II CTD in mRNA processing: beta-turn recognition and beta-spiral model
Descriptor: CTD-peptide, PCF11 protein
Authors:Meinhart, A, Cramer, P.
Deposit date:2004-04-05
Release date:2004-07-13
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Recognition of RNA polymerase II carboxy-terminal domain by 3'-RNA-processing factors.
Nature, 430, 2004
1SZ9
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BU of 1sz9 by Molmil
The RNA polymerase II CTD in mRNA processing: beta-turn recognition and beta-spiral model
Descriptor: PCF11 protein
Authors:Meinhart, A, Cramer, P.
Deposit date:2004-04-05
Release date:2004-07-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Recognition of RNA polymerase II carboxy-terminal domain by 3'-RNA-processing factors.
Nature, 430, 2004
6ZK7
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BU of 6zk7 by Molmil
Crystal Structure of human PYROXD1/FAD complex
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1
Authors:Meinhart, A, Asanovic, I, Martinez, J, Clausen, T.
Deposit date:2020-06-30
Release date:2021-05-12
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The oxidoreductase PYROXD1 uses NAD(P) + as an antioxidant to sustain tRNA ligase activity in pre-tRNA splicing and unfolded protein response.
Mol.Cell, 81, 2021
7AA4
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BU of 7aa4 by Molmil
Structure of ClpC1-NTD bound to a CymA analogue
Descriptor: Negative regulator of genetic competence ClpC/mecB, polymer Cyclomarin A analogue
Authors:Meinhart, A, Morreale, F.E, Kaiser, M, Clausen, T.
Deposit date:2020-09-03
Release date:2021-08-11
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:BacPROTACs mediate targeted protein degradation in bacteria.
Cell, 185, 2022
6QDJ
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BU of 6qdj by Molmil
Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin
Descriptor: 1,4-BUTANEDIOL, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Meinhart, A, Clausen, T, Arnese, R.
Deposit date:2019-01-02
Release date:2019-10-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.884 Å)
Cite:Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin.
Nat Commun, 10, 2019
6QDL
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BU of 6qdl by Molmil
Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin
Descriptor: UNC-45
Authors:Meinhart, A, Clausen, T, Hellerschmied, D.
Deposit date:2019-01-02
Release date:2019-10-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.929 Å)
Cite:Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin.
Nat Commun, 10, 2019
6QDK
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BU of 6qdk by Molmil
Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin
Descriptor: UNC-45,UNC-45
Authors:Meinhart, A, Clausen, T, Hellerschmied, D.
Deposit date:2019-01-02
Release date:2019-10-30
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin.
Nat Commun, 10, 2019
6QDM
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BU of 6qdm by Molmil
Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin
Descriptor: UNC-45,UNC-45
Authors:Meinhart, A, Clausen, T, Hellerschmied, D.
Deposit date:2019-01-02
Release date:2019-10-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin.
Nat Commun, 10, 2019
8B9O
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BU of 8b9o by Molmil
Structure of the C-terminal domain of ClpC2 from Mycobacterium smegmatis
Descriptor: Clp amino terminal domain protein, phospho-arginine
Authors:Meinhart, A, Hoi, D.M, Clausen, T.
Deposit date:2022-10-06
Release date:2023-07-05
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Clp-targeting BacPROTACs impair mycobacterial proteostasis and survival.
Cell, 186, 2023
8B9U
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BU of 8b9u by Molmil
Structure of ClpC1 NTD from Mycobacterium tuberculosis
Descriptor: (MLE)V(MAA)(E9M)G, ATP-dependent Clp protease ATP-binding subunit ClpC1, FORMIC ACID
Authors:Meinhart, A, Hoi, D.M, Clausen, T.
Deposit date:2022-10-10
Release date:2023-07-05
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Clp-targeting BacPROTACs impair mycobacterial proteostasis and survival.
Cell, 186, 2023
8BRH
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BU of 8brh by Molmil
Co-crystal structure of She4 with Myo4 peptide
Descriptor: KLLA0E16699p, Myo4 peptide (LYS-PHE-ILE-VAL-SER-HIS-TYR)
Authors:Arnese, R, Gudino, R, Meinhart, A, Clausen, T.
Deposit date:2022-11-23
Release date:2024-06-05
Last modified:2024-08-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:UNC-45 assisted myosin folding depends on a conserved FX 3 HY motif implicated in Freeman Sheldon Syndrome.
Nat Commun, 15, 2024
8BRG
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BU of 8brg by Molmil
Crystal structure of She4
Descriptor: KLLA0E16699p
Authors:Gudino, R, Arnese, R, Meinhart, A, Clausen, T.
Deposit date:2022-11-23
Release date:2024-06-05
Last modified:2024-08-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:UNC-45 assisted myosin folding depends on a conserved FX 3 HY motif implicated in Freeman Sheldon Syndrome.
Nat Commun, 15, 2024
5FGT
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BU of 5fgt by Molmil
Thaumatin solved by native sulphur-SAD using free-electron laser radiation
Descriptor: L(+)-TARTARIC ACID, Thaumatin-1
Authors:Nass, K.J, Meinhart, A, Barends, T.R.M, Foucar, L, Gorel, A, Aquila, A, Botha, S, Doak, R.B, Koglin, J, Liang, M, Shoeman, R.L, Williams, G.K, Boutet, S, Schlichting, I.
Deposit date:2015-12-21
Release date:2016-06-08
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Protein structure determination by single-wavelength anomalous diffraction phasing of X-ray free-electron laser data.
Iucrj, 3, 2016
5FGX
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BU of 5fgx by Molmil
Thaumatin solved by native sulphur SAD using synchrotron radiation
Descriptor: L(+)-TARTARIC ACID, Thaumatin-1
Authors:Nass, K.J, Meinhart, A, Barends, T.R.M, Foucar, L, Gorel, A, Aquila, A, Botha, S, Doak, R.B, Koglin, J, Liang, M, Shoeman, R.L, Williams, G.J, Boutet, S, Schlichting, I.
Deposit date:2015-12-21
Release date:2016-06-08
Method:X-RAY DIFFRACTION (2.134 Å)
Cite:Protein structure determination by single-wavelength anomalous diffraction phasing of X-ray free-electron laser data.
Iucrj, 3, 2016
4XW3
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BU of 4xw3 by Molmil
Crystal structure of the SPRY domain of the human DEAD-box protein DDX1
Descriptor: ATP-dependent RNA helicase DDX1
Authors:Kellner, J.N, Meinhart, A.
Deposit date:2015-01-28
Release date:2015-09-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the SPRY domain of the human RNA helicase DDX1, a putative interaction platform within a DEAD-box protein.
Acta Crystallogr.,Sect.F, 71, 2015
7BII
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BU of 7bii by Molmil
Crystal structure of Nematocida HUWE1
Descriptor: E3 ubiquitin-protein ligase HUWE1
Authors:Grabarczyk, D.B, Petrova, O.A, Meinhart, A, Kessler, D, Clausen, T.
Deposit date:2021-01-12
Release date:2021-07-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.037 Å)
Cite:HUWE1 employs a giant substrate-binding ring to feed and regulate its HECT E3 domain.
Nat.Chem.Biol., 17, 2021
7QVE
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BU of 7qve by Molmil
Spinach 20S proteasome
Descriptor: Proteasome subunit alpha type, Proteasome subunit alpha type-3, Proteasome subunit beta, ...
Authors:Kandolf, S, Grishkovskaya, I, Meinhart, A, Haselbach, D.
Deposit date:2022-01-21
Release date:2022-05-25
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structure of the plant 26S proteasome.
Plant Commun., 3, 2022
5MBD
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BU of 5mbd by Molmil
Structure of a bacterial light-regulated adenylyl cylcase
Descriptor: Beta subunit of photoactivated adenylyl cyclase, CHLORIDE ION, FLAVIN MONONUCLEOTIDE
Authors:Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I.
Deposit date:2016-11-08
Release date:2017-04-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase.
J. Mol. Biol., 429, 2017
5MBJ
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BU of 5mbj by Molmil
Structure of a bacterial light-regulated adenylyl cyclase
Descriptor: Beta subunit of photoactivated adenylyl cyclase, FLAVIN MONONUCLEOTIDE
Authors:Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I.
Deposit date:2016-11-08
Release date:2017-04-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase.
J. Mol. Biol., 429, 2017
5MBE
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BU of 5mbe by Molmil
Structure of a bacterial light-regulated adenylyl cylcase
Descriptor: Beta subunit of photoactivated adenylyl cyclase, FLAVIN MONONUCLEOTIDE
Authors:Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I.
Deposit date:2016-11-08
Release date:2017-04-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase.
J. Mol. Biol., 429, 2017
5MBH
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BU of 5mbh by Molmil
Structure of a bacterial light-regulated adenylyl cyclase
Descriptor: Beta subunit of photoactivated adenylyl cyclase, FLAVIN MONONUCLEOTIDE
Authors:Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I.
Deposit date:2016-11-08
Release date:2017-04-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase.
J. Mol. Biol., 429, 2017
5MBG
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BU of 5mbg by Molmil
Structure of a bacterial light-regulated adenylyl cyclase
Descriptor: Beta subunit of photoactivated adenylyl cyclase, IODIDE ION
Authors:Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I.
Deposit date:2016-11-08
Release date:2017-04-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase.
J. Mol. Biol., 429, 2017
5MBC
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BU of 5mbc by Molmil
Structure of a bacterial light-regulated adenylyl cylcase
Descriptor: Beta subunit of photoactivated adenylyl cyclase, CHLORIDE ION, FLAVIN MONONUCLEOTIDE
Authors:Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I.
Deposit date:2016-11-08
Release date:2017-04-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase.
J. Mol. Biol., 429, 2017

 

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