Author results

1MHE
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THE HUMAN NON-CLASSICAL MAJOR HISTOCOMPATIBILITY COMPLEX MOLECULE HLA-E
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN HLA-E, BETA-2-MICROGLOBULIN, PEPTIDE (VMAPRTVLL), ...
Authors:O'Callaghan, C.A., Tormo, J., Willcox, B.E., Braud, V.B., Jakobsen, B.K., Stuart, D.I., Mcmichael, A.J., Bell, J.I., Jones, E.Y.
Deposit date:1998-08-24
Release date:1999-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural features impose tight peptide binding specificity in the nonclassical MHC molecule HLA-E.
Mol.Cell, 1, 1998
1TOZ
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NMR STRUCTURE OF THE HUMAN NOTCH-1 LIGAND BINDING REGION
Descriptor:Neurogenic locus notch homolog protein 1
Authors:Hambleton, S., Valeyev, N.Y., Muranyi, A., Knott, V., Werner, J.M., Mcmichael, A.J., Handford, P.A., Downing, A.K.
Deposit date:2004-06-15
Release date:2004-10-12
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural and functional properties of the human notch-1 ligand binding region
STRUCTURE, 12, 2004
1A1M
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MHC CLASS I MOLECULE B*5301 COMPLEXED WITH PEPTIDE TPYDINQML FROM GAG PROTEIN OF HIV2
Descriptor:HLA class I histocompatibility antigen, BW-53 B*5301 alpha chain, Beta-2-microglobulin, ...
Authors:Smith, K.J., Reid, S.W., Harlos, K., Mcmichael, A.J., Stuart, D.I., Bell, J.I., Jones, E.Y.
Deposit date:1997-12-11
Release date:1998-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Bound water structure and polymorphic amino acids act together to allow the binding of different peptides to MHC class I HLA-B53.
Immunity, 4, 1996
1A1N
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MHC CLASS I MOLECULE B*3501 COMPLEXED WITH PEPTIDE VPLRPMTY FROM THE NEF PROTEIN (75-82) OF HIV1
Descriptor:HLA class I histocompatibility antigen, BW-53 B*5301 alpha chain, Beta-2-microglobulin, ...
Authors:Smith, K.J., Reid, S.W., Stuart, D.I., Mcmichael, A.J., Jones, E.Y., Bell, J.I.
Deposit date:1997-12-11
Release date:1998-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:An altered position of the alpha 2 helix of MHC class I is revealed by the crystal structure of HLA-B*3501.
Immunity, 4, 1996
1A1O
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MHC CLASS I MOLECULE B*5301 COMPLEXED WITH PEPTIDE LS6 (KPIVQYDNF) FROM THE MALARIA PARASITE P. FALCIPARUM
Descriptor:HLA class I histocompatibility antigen, BW-53 B*5301 alpha chain, Beta-2-microglobulin, ...
Authors:Smith, K.J., Reid, S.W., Harlos, K., Mcmichael, A.J., Stuart, D.I., Bell, J.I., Jones, E.Y.
Deposit date:1997-12-11
Release date:1998-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Bound water structure and polymorphic amino acids act together to allow the binding of different peptides to MHC class I HLA-B53.
Immunity, 4, 1996
1AGB
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ANTAGONIST HIV-1 GAG PEPTIDES INDUCE STRUCTURAL CHANGES IN HLA B8-HIV-1 GAG PEPTIDE (GGRKKYKL-3R MUTATION)
Descriptor:B*0801, BETA-2 MICROGLOBULIN, HIV-1 GAG PEPTIDE (GGRKKYKL - 3R MUTATION)
Authors:Reid, S.W., Mcadam, S., Smith, K.J., Klenerman, P., O'Callaghan, C.A., Harlos, K., Jakobsen, B.K., Mcmichael, A.J., Bell, J., Stuart, D.I., Jones, E.Y.
Deposit date:1997-03-24
Release date:1997-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Antagonist HIV-1 Gag peptides induce structural changes in HLA B8.
J.Exp.Med., 184, 1996
1AGC
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ANTAGONIST HIV-1 GAG PEPTIDES INDUCE STRUCTURAL CHANGES IN HLA B8-HIV-1 GAG PEPTIDE (GGKKKYQL-7Q MUTATION)
Descriptor:B*0801, BETA-2 MICROGLOBULIN, HIV-1 GAG PEPTIDE (GGKKKYQL - 7Q MUTATION)
Authors:Reid, S.W., Mcadam, S., Smith, K.J., Klenerman, P., O'Callaghan, C.A., Harlos, K., Jakobsen, B.K., Mcmichael, A.J., Bell, J., Stuart, D.I., Jones, E.Y.
Deposit date:1997-03-24
Release date:1997-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Antagonist HIV-1 Gag peptides induce structural changes in HLA B8.
J.Exp.Med., 184, 1996
1AGD
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ANTAGONIST HIV-1 GAG PEPTIDES INDUCE STRUCTURAL CHANGES IN HLA B8-HIV-1 GAG PEPTIDE (GGKKKYKL-INDEX PEPTIDE)
Descriptor:B*0801, BETA-2 MICROGLOBULIN, HIV-1 GAG PEPTIDE (GGKKKYKL - INDEX PEPTIDE)
Authors:Reid, S.W., Mcadam, S., Smith, K.J., Klenerman, P., O'Callaghan, C.A., Harlos, K., Jakobsen, B.K., Mcmichael, A.J., Bell, J., Stuart, D.I., Jones, E.Y.
Deposit date:1997-03-24
Release date:1997-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Antagonist HIV-1 Gag peptides induce structural changes in HLA B8.
J.Exp.Med., 184, 1996
1AGE
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ANTAGONIST HIV-1 GAG PEPTIDES INDUCE STRUCTURAL CHANGES IN HLA B8-HIV-1 GAG PEPTIDE (GGKKKYRL-7R MUTATION)
Descriptor:B*0801, BETA-2 MICROGLOBULIN, HIV-1 GAG PEPTIDE (GGKKKYRL - 7R MUTATION)
Authors:Reid, S.W., Mcadam, S., Smith, K.J., Klenerman, P., O'Callaghan, C.A., Harlos, K., Jakobsen, B.K., Mcmichael, A.J., Bell, J., Stuart, D.I., Jones, E.Y.
Deposit date:1997-03-24
Release date:1997-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Antagonist HIV-1 Gag peptides induce structural changes in HLA B8.
J.Exp.Med., 184, 1996
1AGF
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ANTAGONIST HIV-1 GAG PEPTIDES INDUCE STRUCTURAL CHANGES IN HLA B8-HIV-1 GAG PEPTIDE (GGKKRYKL-5R MUTATION)
Descriptor:B*0801, BETA-2 MICROGLOBULIN, HIV-1 GAG PEPTIDE (GGKKRYKL - 5R MUTATION)
Authors:Reid, S.W., Mcadam, S., Smith, K.J., Klenerman, P., O'Callaghan, C.A., Harlos, K., Jakobsen, B.K., Mcmichael, A.J., Bell, J., Stuart, D.I., Jones, E.Y.
Deposit date:1997-03-24
Release date:1997-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Antagonist HIV-1 Gag peptides induce structural changes in HLA B8.
J.Exp.Med., 184, 1996
1OGA
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A STRUCTURAL BASIS FOR IMMUNODOMINANT HUMAN T-CELL RECEPTOR RECOGNITION.
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, BETA-2-MICROGLOBULIN, GILGFVFTL, ...
Authors:Stewart-Jones, G.B.E., McMichael, A.J., Bell, J.I., Stuart, D.I., Jones, E.Y.
Deposit date:2003-04-28
Release date:2003-06-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A Structural Basis for Immunodominant Human T Cell Receptor Recognition
Nat.Immunol., 4, 2003
2BSR
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CRYSTAL STRUCTURES AND KIR3DL1 RECOGNITION OF THREE IMMUNODOMINANT VIRAL PEPTIDES COMPLEXED TO HLA-B2705
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-27 ALPHA CHAIN PRECURSOR, BETA-2-MICROGLOBULIN, ...
Authors:Stewart-Jones, G.B.E., Di Gleria, K., Kollnberger, S., Mcmichael, A.J., Jones, E.Y., Bowness, P.
Deposit date:2005-05-23
Release date:2005-05-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures and Kir3Dl1 Recognition of Three Immunodominant Viral Peptides Complexed to Hla-B2705
Eur.J.Immunol., 35, 2005
2BSS
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CRYSTAL STRUCTURES AND KIR3DL1 RECOGNITION OF THREE IMMUNODOMINANT VIRAL PEPTIDES COMPLEXED TO HLA-B2705
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN B-27 ALPHA CHAIN, BETA-2-MICROGLOBULIN, HIV PEPTIDE
Authors:Stewart-Jones, G.B.E., Di Gleria, K., Kollnberger, S., Mcmichael, A.J., Jones, E.Y., Bowness, P.
Deposit date:2005-05-23
Release date:2005-05-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures and Kir3Dl1 Recognition of Three Immunodominant Viral Peptides Complexed to Hla-B2705
Eur.J.Immunol., 35, 2005
2BST
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CRYSTAL STRUCTURES AND KIR3DL1 RECOGNITION OF THREE IMMUNODOMINANT VIRAL PEPTIDES COMPLEXED TO HLA-B2705
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-27 ALPHA CHAIN PRECURSOR, BETA-2-MICROGLOBULIN, ...
Authors:Stewart-Jones, G.B.E., diGleria, K., Kollnberger, S., McMichael, A.J., Bowness, P., Jones, E.Y.
Deposit date:2005-05-23
Release date:2005-05-24
Last modified:2015-05-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures and Kir3Dl1 Recognition of Three Immunodominant Viral Peptides Complexed to Hla-B2705
Eur.J.Immunol., 35, 2005
2BVO
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STRUCTURES OF THREE HIV-1 HLA-B5703-PEPTIDE COMPLEXES AND IDENTIFICATION OF RELATED HLAS POTENTIALLY ASSOCIATED WITH LONG-TERM NON-PROGRESSION
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-57 ALPHA CHAIN, BETA-2-MICROGLOBULIN, ...
Authors:Stewart-Jones, G.B., Gillespie, G., Overton, I.M., Kaul, R., Roche, P., Mcmichael, A.J., Rowland-Jones, S., Jones, E.Y.
Deposit date:2005-07-01
Release date:2005-09-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structures of Three HIV-1 Hla-B5703-Peptide Complexes and Identification of Related Hlas Potentially Associated with Long-Term Nonprogression.
J.Immunol., 175, 2005
2BVP
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STRUCTURES OF THREE HIV-1 HLA-B5703-PEPTIDE COMPLEXES AND IDENTIFICATION OF RELATED HLAS POTENTIALLY ASSOCIATED WITH LONG-TERM NON-PROGRESSION
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-57 ALPHA CHAIN, BETA-2-MICROGLOBULIN, ...
Authors:Stewart-Jones, G.B., Gillespie, G., Overton, I.M., Kaul, R., Roche, P., Mcmichael, A.J., Rowland-Jones, S., Jones, E.Y.
Deposit date:2005-07-01
Release date:2005-09-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structures of Three HIV-1 Hla-B5703-Peptide Complexes and Identification of Related Hlas Potentially Associated with Long-Term Nonprogression.
J.Immunol., 175, 2005
2BVQ
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STRUCTURES OF THREE HIV-1 HLA-B5703-PEPTIDE COMPLEXES AND IDENTIFICATION OF RELATED HLAS POTENTIALLY ASSOCIATED WITH LONG-TERM NON-PROGRESSION
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-57 ALPHA CHAIN, BETA-2-MICROGLOBULIN, ...
Authors:Stewart-Jones, G.B., Gillespie, G., Overton, I.M., Kaul, R., Roche, P., Mcmichael, A.J., Rowland-Jones, S., Jones, E.Y.
Deposit date:2005-07-01
Release date:2005-09-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of Three HIV-1 Hla-B5703-Peptide Complexes and Identification of Related Hlas Potentially Associated with Long-Term Nonprogression.
J.Immunol., 175, 2005
2C7U
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CONFLICTING SELECTIVE FORCES AFFECT CD8 T-CELL RECEPTOR CONTACT SITES IN AN HLA-A2 IMMUNODOMINANT HIV EPITOPE.
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, BETA-2-MICROGLOBULIN, ...
Authors:Iversen, A.K., Stewart-Jones, G., Learn, G.H., Christie, N., Sylvester-Hviid, C., Armitage, A.E., Kaul, R., Beattie, T., Lee, J.K., Li, Y., Chotiyarnwong, P., Dong, T., Xu, X., Luscher, M.A., MacDonald, K., Ullum, H., Klarlund-Pedersen, B., Skinhoj, P., Fugger, J.L., Buus, S., Mullins, J.I., Jones, E.Y., van der Merwe, P.A., McMichael, A.J.
Deposit date:2005-11-29
Release date:2006-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Conflicting Selective Forces Affect T Cell Receptor Contacts in an Immunodominant Human Immunodeficiency Virus Epitope.
Nat.Immunol., 7, 2006
2V2W
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T CELL CROSS-REACTIVITY AND CONFORMATIONAL CHANGES DURING TCR ENGAGEMENT
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, BETA-2 MICROGLOBULIN, ...
Authors:Lee, J.K., Stewart-Jones, G., Dong, T., Harlos, K., Di Gleria, K., Dorrell, L., Douek, D.C., Van Der Merwe, P.A., Jones, E.Y., Mcmichael, A.J.
Deposit date:2007-06-07
Release date:2007-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:T Cell Cross-Reactivity and Conformational Changes During Tcr Engagement.
J.Exp.Med., 200, 2004
2V2X
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T CELL CROSS-REACTIVITY AND CONFORMATIONAL CHANGES DURING TCR ENGAGEMENT.
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, BETA-2 MICROGLOBULIN, ...
Authors:Lee, J.K., Stewart-Jones, G., Dong, T., harlos, K., Di Gleria, K., Dorrell, L., Douek, D.C., van der Merwe, P.A., Jones, E.Y., McMichael, A.J.
Deposit date:2007-06-07
Release date:2007-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:T Cell Cross-Reactivity and Conformational Changes During Tcr Engagement.
J.Exp.Med., 200, 2004
2YPK
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STRUCTURAL FEATURES UNDERLYING T-CELL RECEPTOR SENSITIVITY TO CONCEALED MHC CLASS I MICROPOLYMORPHISMS
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-57 ALPHA CHAIN, BETA-2-MICROGLOBULIN, ...
Authors:Stewart-Jones, G.B., Simpson, P., Van Der Merwe, P.A., Easterbrook, P., Mcmichael, A.J., Rowland-Jones, S.L., Jones, E.Y., Gillespie, G.M.
Deposit date:2012-10-30
Release date:2012-11-28
Last modified:2013-01-16
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural Features Underlying T-Cell Receptor Sensitivity to Concealed Mhc Class I Micropolymorphisms.
Proc.Natl.Acad.Sci.USA, 109, 2012
2YPL
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STRUCTURAL FEATURES UNDERLYING T-CELL RECEPTOR SENSITIVITY TO CONCEALED MHC CLASS I MICROPOLYMORPHISMS
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-57 ALPHA CHAIN, BETA-2-MICROGLOBULIN, ...
Authors:Stewart-Jones, G.B., Simpson, P., van der Merwe, P.A., Easterbrook, P., McMichael, A.J., Rowland-Jones, S.L., Jones, E.Y., Gillespie, G.M.
Deposit date:2012-10-30
Release date:2012-11-28
Last modified:2013-01-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Features Underlying T-Cell Receptor Sensitivity to Concealed Mhc Class I Micropolymorphisms.
Proc.Natl.Acad.Sci.USA, 109, 2012
6GGM
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HLA-E*01:03 IN COMPLEX WITH THE MTB44 PEPTIDE VARIANT: MTB44*P2-PHE.
Descriptor:MHC class I antigen, Beta-2-microglobulin, Mtb44*P2-Phe peptide variant (ARG-PHE-PRO-ALA-LYS-ALA-PRO-LEU-LEU), ...
Authors:Walters, L.C., Gillespie, G.M., McMichael, A.J., Rozbesky, D., Jones, E.Y., Harlos, K.
Deposit date:2018-05-03
Release date:2018-08-08
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (2.734 Å)
Cite:Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Nat Commun, 9, 2018
6GH1
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HLA-E*01:03 IN COMPLEX WITH MTB44
Descriptor:MHC class I antigen, Beta-2-microglobulin, Enoyl-[acyl-carrier-protein] reductase [NADH], ...
Authors:Walters, L.C., Gillespie, G.M., McMichael, A.J., Rozbesky, D., Jones, E.Y., Harlos, K.
Deposit date:2018-05-04
Release date:2018-08-08
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Nat Commun, 9, 2018
6GH4
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HLA-E*01:03 IN COMPLEX WITH THE MTB44 PEPTIDE VARIANT: MTB44*P2-GLN.
Descriptor:MHC class I antigen, Beta-2-microglobulin, ARG-GLN-PRO-ALA-LYS-ALA-PRO-LEU-LEU, ...
Authors:Walters, L.C., Gillespie, G.M., McMichael, A.J., Rozbesky, D., Jones, E.Y., Harlos, K.
Deposit date:2018-05-04
Release date:2018-08-08
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Nat Commun, 9, 2018
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