Author results

2BPA
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ATOMIC STRUCTURE OF SINGLE-STRANDED DNA BACTERIOPHAGE PHIX174 AND ITS FUNCTIONAL IMPLICATIONS
Descriptor:DNA (5'-D(*AP*AP*AP*AP*C)-3'), PROTEIN (SUBUNIT OF BACTERIOPHAGE PHIX174)
Authors:McKenna, R., Xia, D., Willingmann, P., Ilag, L.L., Krishnaswamy, S., Rossmann, M.G., Olson, N.H., Baker, T.S., Incardona, N.L.
Deposit date:1991-12-03
Release date:1991-12-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Atomic structure of single-stranded DNA bacteriophage phi X174 and its functional implications.
Nature, 355, 1992
5JMZ
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CARBONIC ANHYDRASE IX-MIMIC IN COMPLEX WITH U-NO2
Descriptor:Carbonic anhydrase 2, ZINC ION, DIMETHYL SULFOXIDE, ...
Authors:McKenna, R., Mboge, M.Y., Mahon, B.P.
Deposit date:2016-04-29
Release date:2017-05-03
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Carbonic Anhydrase IX-mimic IN Complex WITH U-NO2
To Be Published
5JN1
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CARBONIC ANHYDRASE IX-MIMIC IN COMPLEX WITH U-CH3
Descriptor:Carbonic anhydrase 2, ZINC ION, 4-{[(3,5-dimethylphenyl)carbamoyl]amino}benzene-1-sulfonamide, ...
Authors:McKenna, R., Mboge, M.Y., Mahon, B.P.
Deposit date:2016-04-29
Release date:2017-05-03
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.517 Å)
Cite:Carbonic Anhydrase IX-mimic IN Complex WITH U-CH3
To Be Published
5JN3
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CARBONIC ANHYDRASE IX-MIMIC IN COMPLEX WITH U-F
Descriptor:Carbonic anhydrase 2, ZINC ION, DIMETHYL SULFOXIDE, ...
Authors:McKenna, R., Mboge, M.Y., Mahon, B.P.
Deposit date:2016-04-29
Release date:2017-05-03
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Carbonic Anhydrase IX-mimic IN Complex WITH U-F
To Be Published
5JN7
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CARBONIC ANHYDRASE II IN COMPLEX WITH U-CH3
Descriptor:Carbonic anhydrase 2, ZINC ION, 4-{[(3,5-dimethylphenyl)carbamoyl]amino}benzene-1-sulfonamide, ...
Authors:McKenna, R., Mboge, M.Y., Mahon, B.P.
Deposit date:2016-04-29
Release date:2017-05-03
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.517 Å)
Cite:Carbonic Anhydrase II In Complex WITH U-CH3
To Be Published
1KVP
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STRUCTURAL ANALYSIS OF THE SPIROPLASMA VIRUS, SPV4, IMPLICATIONS FOR EVOLUTIONARY VARIATION TO OBTAIN HOST DIVERSITY AMONG THE MICROVIRIDAE, ELECTRON MICROSCOPY, ALPHA CARBONS ONLY
Descriptor:SPV4 CAPSID PROTEIN VP1
Authors:McKenna, R.
Deposit date:1997-12-12
Release date:1999-02-23
Last modified:2011-07-13
Method:ELECTRON MICROSCOPY (27 Å)
Cite:Structural analysis of the Spiroplasma virus, SpV4: implications for evolutionary variation to obtain host diversity among the Microviridae.
Structure, 6, 1998
3MYU
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MYCOPLASMA GENITALIUM MG289
Descriptor:High affinity transport system protein p37, 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, ACETATE ION
Authors:Sippel, K.H., Boehlein, S.K., Govindasamy, L., Namiki, K., Satai, Y., Quirit, J.G., Agbandje-McKenna, M., Goodison, S., Rosser, C.J., Sankaran, B., McKenna, R.
Deposit date:2010-05-11
Release date:2010-10-20
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Insights into Mycoplasma genitalium metabolism revealed by the structure of MG289, an extracytoplasmic thiamine binding lipoprotein.
Proteins, 79, 2011
1MOO
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SITE SPECIFIC MUTANT (H64A) OF HUMAN CARBONIC ANHYDRASE II AT HIGH RESOLUTION
Descriptor:Carbonic Anhydrase II, ZINC ION, MERCURY (II) ION, ...
Authors:Duda, D.M., Govindasamy, L., Agbandje-McKenna, M., Tu, C.K., Silverman, D.N., McKenna, R.
Deposit date:2002-09-09
Release date:2002-09-18
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:The refined atomic structure of carbonic anhydrase II at 1.05 A resolution: implications of chemical rescue of proton transfer.
Acta Crystallogr.,Sect.D, 59, 2003
1SGU
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COMPARING THE ACCUMULATION OF ACTIVE SITE AND NON-ACTIVE SITE MUTATIONS IN THE HIV-1 PROTEASE
Descriptor:POL polyprotein, N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE
Authors:Clemente, J.C., Moose, R.E., Hemrajani, R., Govindasamy, L., Reutzel, R., Mckenna, R., Abandje-McKenna, M., Goodenow, M.M., Dunn, B.M.
Deposit date:2004-02-24
Release date:2004-10-05
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Comparing the Accumulation of Active- and Nonactive-Site Mutations in the HIV-1 Protease.
Biochemistry, 43, 2004
1SH9
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COMPARING THE ACCUMULATION OF ACTIVE SITE AND NON-ACTIVE SITE MUTATIONS IN THE HIV-1 PROTEASE
Descriptor:POL polyprotein, RITONAVIR
Authors:Clemente, J.C., Moose, R.E., Hemrajani, R., Govindasamy, L., Reutzel, R., McKenna, R., Abanje-McKenna, M., Goodenow, M.M., Dunn, B.M.
Deposit date:2004-02-25
Release date:2004-10-05
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Comparing the Accumulation of Active- and Nonactive-Site Mutations in the HIV-1 Protease.
Biochemistry, 43, 2004
3EKI
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STRUCTURAL INSIGHTS OF THE MYCOPLASMA HYORHINIS PROTEIN MH-P37: A PUTATIVE THIAMINE PYROPHOSPHATE TRANSPORTER
Descriptor:High affinity transport system protein p37, THIAMINE DIPHOSPHATE, GLYCEROL, ...
Authors:Sippel, K.H., Robbins, A.H., Reutzel, R., McKenna, R.
Deposit date:2008-09-19
Release date:2009-06-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insights into the extracytoplasmic thiamine-binding lipoprotein p37 of Mycoplasma hyorhinis
J.Bacteriol., 191, 2009
3OIK
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HUMAN CARBONIC ANHYDRASE II MUTANT A65S, N67Q (CA IX MIMIC) BOUND BY 2-ETHYLESTRADIOL 3,17-O,O-BIS-SULFAMATE
Descriptor:Carbonic anhydrase 2, ZINC ION, (9BETA,13ALPHA,14BETA,17ALPHA)-2-ETHYLESTRA-1(10),2,4-TRIENE-3,17-DIYL DISULFAMATE, ...
Authors:Sippel, K.H., Stander, B.A., Robbins, A.H., Tu, C.K., Agbandje-McKenna, M., Silverman, D.N., Joubert, A.M., McKenna, R.
Deposit date:2010-08-19
Release date:2011-07-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Characterization of Carbonic Anhydrase Isozyme Specific Inhibition by Sulfamated 2-Ethylestra Compounds
LETT.DRUG DES.DISCOVERY, 8, 2011
3OIL
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HUMAN CARBONIC ANHYDRASE II MUTANT A65S, N67Q (CA IX MIMIC) BOUND BY 2-ETHYLESTRADIOL 3-O-SULFAMATE
Descriptor:Carbonic anhydrase 2, ZINC ION, (14beta,17alpha)-2-ethyl-17-hydroxyestra-1(10),2,4-trien-3-yl sulfamate
Authors:Sippel, K.H., Stander, B.A., Robbins, A.H., Tu, C.K., Agbandje-McKenna, M., Silverman, D.N., Joubert, A.M., McKenna, R.
Deposit date:2010-08-19
Release date:2011-07-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Characterization of Carbonic Anhydrase Isozyme Specific Inhibition by Sulfamated 2-Ethylestra Compounds
LETT.DRUG DES.DISCOVERY, 8, 2011
3OIM
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HUMAN CARBONIC ANHYDRASE II BOUND BY 2-ETHYLESTRADIOL 3-O-SULFAMATE
Descriptor:Carbonic anhydrase 2, ZINC ION, (14beta,17alpha)-2-ethyl-17-hydroxyestra-1(10),2,4-trien-3-yl sulfamate, ...
Authors:Sippel, K.H., Stander, B.A., Robbins, A.H., Tu, C.K., Agbandje-McKenna, M., Silverman, D.N., Joubert, A.M., McKenna, R.
Deposit date:2010-08-19
Release date:2011-07-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Characterization of Carbonic Anhydrase Isozyme Specific Inhibition by Sulfamated 2-Ethylestra Compounds
LETT.DRUG DES.DISCOVERY, 8, 2011
3OKU
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HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH 2-ETHYLESTRONE-3-O-SULFAMATE
Descriptor:Carbonic anhydrase 2, ZINC ION, (9beta)-2-ethyl-17-oxoestra-1(10),2,4-trien-3-yl sulfamate, ...
Authors:Sippel, K.H., Stander, B.A., Robbins, A.H., Tu, C.K., Agbandje-McKenna, M., Silverman, D.N., Joubert, A.M., McKenna, R.
Deposit date:2010-08-25
Release date:2011-07-06
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Characterization of Carbonic Anhydrase Isozyme Specific Inhibition by Sulfamated 2-Ethylestra Compounds
LETT.DRUG DES.DISCOVERY, 8, 2011
3OKV
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HUMAN CARBONIC ANHYDRASE II A65S, N67Q (CA IX MIMIC) BOUND WITH 2-ETHYLESTRONE 3-O-SULFAMATE
Descriptor:Carbonic anhydrase 2, ZINC ION, (9beta)-2-ethyl-17-oxoestra-1(10),2,4-trien-3-yl sulfamate, ...
Authors:Sippel, K.H., Stander, B.A., Robbins, A.H., Tu, C.K., Agbandje-McKenna, M., Silverman, D.N., Joubert, A.M., McKenna, R.
Deposit date:2010-08-25
Release date:2011-07-06
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Characterization of Carbonic Anhydrase Isozyme Specific Inhibition by Sulfamated 2-Ethylestra Compounds
LETT.DRUG DES.DISCOVERY, 8, 2011
4FIK
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HUMAN CARBONIC ANHYDRASE II H64A COMPLEXED WITH THIOXOLONE HYDROLYSIS PRODUCTS
Descriptor:Carbonic anhydrase 2, ZINC ION, 2,4-dihydroxybenzenesulfenic acid, ...
Authors:Sippel, K.H., Genis, C., Govindasamy, L., Agbandje-McKenna, M., Tripp, B.C., McKenna, R.
Deposit date:2012-06-08
Release date:2012-06-27
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Synchrotron Radiation Provides a Plausible Explanation for the Generation of a Free Radical Adduct of Thioxolone in Mutant Carbonic Anhydrase II.
J Phys Chem Lett, 1, 2010
1RDW
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ACTIN CRYSTAL DYNAMICS: STRUCTURAL IMPLICATIONS FOR F-ACTIN NUCLEATION, POLYMERIZATION AND BRANCHING MEDIATED BY THE ANTI-PARALLEL DIMER
Descriptor:Actin, alpha skeletal muscle, MAGNESIUM ION, ...
Authors:Reutzel, R., Yoshioka, C., Govindasamy, L., Yarmola, E.G., Agbandje-Mckenna, M., Bubb, M.R., Mckenna, R.
Deposit date:2003-11-06
Release date:2003-12-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Actin crystal dynamics: structural implications for F-actin nucleation, polymerization, and branching mediated by the anti-parallel dimer.
J.Struct.Biol., 146, 2004
1RFQ
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ACTIN CRYSTAL DYNAMICS: STRUCTURAL IMPLICATIONS FOR F-ACTIN NUCLEATION, POLYMERIZATION AND BRANCHING MEDIATED BY THE ANTI-PARALLEL DIMER
Descriptor:Actin, alpha skeletal muscle, MAGNESIUM ION, ...
Authors:Reutzel, R., Yoshioka, C., Govindasamy, L., Yarmola, E.G., Agbandje-McKenna, M., Bubb, M.R., McKenna, R.
Deposit date:2003-11-10
Release date:2003-12-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Actin crystal dynamics: structural implications for F-actin nucleation, polymerization, and branching mediated by the anti-parallel dimer.
J.Struct.Biol., 146, 2004
3KKY
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STRUCTURE OF MANGANESE SUPEROXIDE DISMUTASE FROM DEINOCOCCUS RADIODURANS IN THE ORTHORHOMBIC SPACE GROUP P212121: A CASE STUDY OF MISTAKEN IDENTITY
Descriptor:Superoxide dismutase [Mn], MANGANESE (II) ION
Authors:Govindasamy, L., Mikulski, R., McKenna, M.A., Silverman, D.N., McKenna, R.
Deposit date:2009-11-06
Release date:2010-11-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of Manganese Superoxide dismutase from Deinococcus Radiodurans in the orthorhombic space group P212121: A case study of mistaken identity
To be Published
1Z1C
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STRUCTURAL DETERMINANTS OF TISSUE TROPISM AND IN VIVO PATHOGENICITY FOR THE PARVOVIRUS MINUTE VIRUS OF MICE
Descriptor:5'-D(*AP*TP*CP*CP*TP*CP*TP*AP*TP*CP*AP*C)-3', 5'-D(*AP*CP*AP*CP*CP*AP*AP*AP*A)-3', Coat protein VP2, ...
Authors:Kontou, M., Govindasamy, L., Nam, H.J., Bryant, N., Llamas-Saiz, A.L., Foces-Foces, C., Hernando, E., Rubio, M.P., McKenna, R., Almendral, J.M., Agbandje-McKenna, M.
Deposit date:2005-03-03
Release date:2005-09-06
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural determinants of tissue tropism and in vivo pathogenicity for the parvovirus minute virus of mice.
J.Virol., 79, 2005
3UX1
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STRUCTURAL CHARACTERIZATION OF ADENO-ASSOCIATED VIRUS SEROTYPE 9
Descriptor:Capsid protein VP1
Authors:DiMattia, M.A., Nam, H.-J., Van Vliet, K., Mitchell, M., McCall, A., Bennett, A., Gurda, B., McKenna, R., Potter, M., Sakai, Y., Byrne, B.J., Muzyczka, N., Aslanidi, G., Zolotukhin, S., Olson, N., Sinkovitis, R., Baker, T.S., Agbandje-McKenna, M.
Deposit date:2011-12-03
Release date:2012-05-02
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural insight into the unique properties of adeno-associated virus serotype 9.
J.Virol., 86, 2012
6CBE
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ATOMIC STRUCTURE OF A RATIONALLY ENGINEERED GENE DELIVERY VECTOR, AAV2.5
Descriptor:Capsid protein VP1
Authors:Burg, M., Rosebrough, C., Drouin, L., Bennett, A., Mietzsch, M., Chipman, P., McKenna, R., Sousa, D., Potter, M., Byrne, B., Kozyreva, O.G., Samulski, R.J., Agbandje-McKenna, M.
Deposit date:2018-02-02
Release date:2018-05-30
Last modified:2018-08-29
Method:ELECTRON MICROSCOPY (2.78 Å)
Cite:Atomic structure of a rationally engineered gene delivery vector, AAV2.5.
J. Struct. Biol., 203, 2018
1LCU
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POLYLYSINE INDUCES AN ANTIPARALLEL ACTIN DIMER THAT NUCLEATES FILAMENT ASSEMBLY: CRYSTAL STRUCTURE AT 3.5 A RESOLUTION
Descriptor:Actin, alpha skeletal muscle, CALCIUM ION, ...
Authors:Bubb, M.R., Govindasamy, L., Yarmola, E.G., Vorobiev, S.M., Almo, S.C., Somasundaram, T., Chapman, M.S., Agbandje-Mckenna, M., Mckenna, R.
Deposit date:2002-04-06
Release date:2002-05-01
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Polylysine induces an antiparallel actin dimer that nucleates filament assembly: crystal structure at 3.5-A resolution.
J.Biol.Chem., 277, 2002
1NM8
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STRUCTURE OF HUMAN CARNITINE ACETYLTRANSFERASE: MOLECULAR BASIS FOR FATTY ACYL TRANSFER
Descriptor:Carnitine O-acetyltransferase
Authors:Wu, D., Govindasamy, L., Lian, W., Gu, Y., Kukar, T., Agbandje-McKenna, M., McKenna, R.
Deposit date:2003-01-09
Release date:2003-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of Human Carnitine Acetyltransferase. Molecular Basis for Fatty Acyl Transfer
J.Biol.Chem., 278, 2003