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6ZJK
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BU of 6zjk by Molmil
Ribonucleotide reductase R2 subunit from Clostridium botulinum
Descriptor: FE (III) ION, GLYCEROL, Ribonucleoside-diphosphate reductase subunit beta
Authors:Martinez-Carranza, M, Stenmark, P.
Deposit date:2020-06-29
Release date:2020-09-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:A ribonucleotide reductase from Clostridium botulinum reveals distinct evolutionary pathways to regulation via the overall activity site.
J.Biol.Chem., 295, 2020
8BYP
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BU of 8byp by Molmil
Botulinum neurotoxin serotype X in complex with NTNH/X
Descriptor: Botulinum neurotoxin type X, NTNH/X
Authors:Martinez-Carranza, M, Skerlova, J, Stenmark, P.
Deposit date:2022-12-15
Release date:2023-02-08
Last modified:2023-10-18
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Structure and activity of botulinum neurotoxin X.
Biorxiv, 2023
6I2G
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BU of 6i2g by Molmil
ALFA-tag binding nanobody (NbALFA) bound to ALFA-tag peptide.
Descriptor: ALFA nanobody, N7P-SER-ARG-LEU-GLU-GLU-GLU-LEU-ARG-ARG-ARG-LEU-THR-GLU-LPD, SULFATE ION
Authors:Martinez-Carranza, M, Stenmark, P.
Deposit date:2018-11-01
Release date:2019-09-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The ALFA-tag is a highly versatile tool for nanobody-based bioscience applications.
Nat Commun, 10, 2019
8C5H
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BU of 8c5h by Molmil
NbSyt1 anti-(rat Synaptotagmin-1) nanobody bound to target cytosolic domain of Synaptotagmin-1
Descriptor: CALCIUM ION, GLYCEROL, NbSyt1 nanobody, ...
Authors:Martinez-Carranza, M, Stenmark, P.
Deposit date:2023-01-09
Release date:2023-08-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:A Versatile Synaptotagmin-1 Nanobody Provides Perturbation-Free Live Synaptic Imaging And Low Linkage-Error in Super-Resolution Microscopy.
Small Methods, 7, 2023
6FLS
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BU of 6fls by Molmil
Pentapeptide repeat family protein from Clostridium botulinum
Descriptor: GLYCEROL, Pentapeptide repeat family protein
Authors:Martinez-Carranza, M, Stenmark, P.
Deposit date:2018-01-27
Release date:2018-08-15
Last modified:2018-12-26
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Cotranslational Folding of a Pentarepeat beta-Helix Protein.
J. Mol. Biol., 430, 2018
7P3F
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BU of 7p3f by Molmil
Streptomyces coelicolor dATP/ATP-loaded NrdR in complex with its cognate DNA
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (50-MER), ...
Authors:Martinez-Carranza, M, Stenmark, P.
Deposit date:2021-07-07
Release date:2022-05-11
Last modified:2022-06-08
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:A nucleotide-sensing oligomerization mechanism that controls NrdR-dependent transcription of ribonucleotide reductases.
Nat Commun, 13, 2022
7P3Q
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BU of 7p3q by Molmil
Streptomyces coelicolor dATP/ATP-loaded NrdR octamer
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Transcriptional repressor NrdR, ...
Authors:Martinez-Carranza, M, Stenmark, P.
Deposit date:2021-07-08
Release date:2022-05-11
Last modified:2022-06-08
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:A nucleotide-sensing oligomerization mechanism that controls NrdR-dependent transcription of ribonucleotide reductases.
Nat Commun, 13, 2022
7P37
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BU of 7p37 by Molmil
Streptomyces coelicolor ATP-loaded NrdR
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Transcriptional repressor NrdR, ZINC ION
Authors:Martinez-Carranza, M, Stenmark, P.
Deposit date:2021-07-07
Release date:2022-05-11
Last modified:2022-06-08
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:A nucleotide-sensing oligomerization mechanism that controls NrdR-dependent transcription of ribonucleotide reductases.
Nat Commun, 13, 2022
8C5Y
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BU of 8c5y by Molmil
RPA tetrameric supercomplex from Pyrococcus abyssi
Descriptor: RPA14 subunit of the hetero-oligomeric complex involved in homologous recombination, RPA32 subunit of the hetero-oligomeric complex involved in homologous recombination, Replication factor A, ...
Authors:Madru, C, Martinez-Carranza, M, Legrand, P, Sauguet, L.
Deposit date:2023-01-10
Release date:2023-05-03
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:DNA-binding mechanism and evolution of replication protein A.
Nat Commun, 14, 2023
8C5Z
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BU of 8c5z by Molmil
RPA tetrameric supercomplex with AROD-OB-1
Descriptor: RPA14 subunit of the hetero-oligomeric complex involved in homologous recombination, RPA32 subunit of the hetero-oligomeric complex involved in homologous recombination, Replication factor A, ...
Authors:Madru, C, Martinez-Carranza, M, Legrand, P, Sauguet, L.
Deposit date:2023-01-10
Release date:2023-05-10
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:DNA-binding mechanism and evolution of replication protein A.
Nat Commun, 14, 2023
8OEJ
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BU of 8oej by Molmil
Extended RPA-DNA nucleoprotein filament
Descriptor: RPA14 subunit of the hetero-oligomeric complex involved in homologous recombination, RPA32 subunit of the hetero-oligomeric complex involved in homologous recombination, Replication factor A, ...
Authors:Madru, C, Martinez-Carranza, M, Sauguet, L.
Deposit date:2023-03-10
Release date:2023-05-10
Method:ELECTRON MICROSCOPY (7.96 Å)
Cite:DNA-binding mechanism and evolution of replication protein A.
Nat Commun, 14, 2023
8OEL
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BU of 8oel by Molmil
Condensed RPA-DNA nucleoprotein filament
Descriptor: RPA14 subunit of the hetero-oligomeric complex involved in homologous recombination, RPA32 subunit of the hetero-oligomeric complex involved in homologous recombination, Replication factor A, ...
Authors:Madru, C, Martinez-Carranza, M, Sauguet, L.
Deposit date:2023-03-10
Release date:2023-06-14
Method:ELECTRON MICROSCOPY (8.24 Å)
Cite:DNA-binding mechanism and evolution of replication protein A.
Nat Commun, 14, 2023
8PPU
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BU of 8ppu by Molmil
Pyrococcus abyssi DNA polymerase D (PolD) in its editing mode bound to a primer/template substrate containing three consecutive mismatches
Descriptor: DNA (5'-D(P*AP*GP*CP*AP*CP*GP*GP*CP*TP*CP*GP*GP*CP*CP*CP*GP*G)-3'), DNA (5'-D(P*CP*CP*GP*GP*GP*CP*CP*GP*AP*GP*CP*CP*GP*TP*(GS)P*(C7R)P*(PST)P*(PST)P*(PST))-3'), DNA polymerase II small subunit, ...
Authors:Betancurt-Anzola, L, Martinez-Carranza, M, Zatopek, K.M, Gardner, A.F, Sauguet, L.
Deposit date:2023-07-10
Release date:2023-12-20
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Molecular basis for proofreading by the unique exonuclease domain of Family-D DNA polymerases.
Nat Commun, 14, 2023
8PPV
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BU of 8ppv by Molmil
Intermediate conformer of Pyrococcus abyssi DNA polymerase D (PolD) bound to a primer/template substrate containing three consecutive mismatches
Descriptor: DNA (5'-D(*P*CP*CP*GP*GP*GP*CP*CP*GP*AP*GP*CP*CP*GP*TP*(GS)P*(G7P)P*(PST)P*(PST)P*(PST))-3'), DNA (5'-D(P*AP*GP*CP*AP*CP*GP*GP*CP*TP*CP*GP*GP*CP*CP*CP*GP*G)-3'), DNA polymerase II small subunit, ...
Authors:Betancurt-Anzola, L, Martinez-Carranza, M, Zatopek, K.M, Gardner, A.F, Sauguet, L.
Deposit date:2023-07-10
Release date:2023-12-20
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Molecular basis for proofreading by the unique exonuclease domain of Family-D DNA polymerases.
Nat Commun, 14, 2023
8PPT
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BU of 8ppt by Molmil
Pyrococcus abyssi DNA polymerase D (PolD) in its editing mode bound to a primer/template substrate containing a mismatch
Descriptor: DNA (5'-D(P*AP*GP*CP*AP*CP*GP*GP*CP*TP*CP*GP*GP*CP*CP*CP*GP*G)-3'), DNA (5'-D(P*CP*CP*GP*GP*GP*CP*CP*GP*AP*GP*CP*CP*GP*TP*GP*CP*TP*TP*T)-3'), DNA polymerase II small subunit, ...
Authors:Betancurt-Anzola, L, Martinez-Carranza, M, Zatopek, K.M, Gardner, A.F, Sauguet, L.
Deposit date:2023-07-10
Release date:2023-12-20
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Molecular basis for proofreading by the unique exonuclease domain of Family-D DNA polymerases.
Nat Commun, 14, 2023
7QFP
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BU of 7qfp by Molmil
Cryo-EM structure of Botulinum neurotoxin serotype E
Descriptor: Botulinum neurotoxin
Authors:Kosenina, S, Martinez-Carranza, M, Davies, J.R, Masuyer, G, Stenmark, P.
Deposit date:2021-12-06
Release date:2022-01-26
Last modified:2022-02-02
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural Analysis of Botulinum Neurotoxins Type B and E by Cryo-EM.
Toxins, 14, 2021
7QFQ
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BU of 7qfq by Molmil
Cryo-EM structure of Botulinum neurotoxin serotype B
Descriptor: Botulinum neurotoxin type B
Authors:Kosenina, S, Martinez-Carranza, M, Davies, J.R, Masuyer, G, Stenmark, P.
Deposit date:2021-12-06
Release date:2022-01-26
Last modified:2022-02-02
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural Analysis of Botulinum Neurotoxins Type B and E by Cryo-EM.
Toxins, 14, 2021
8AAJ
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BU of 8aaj by Molmil
Crystal structure of the Pyrococcus abyssi RPA (apo form)
Descriptor: RPA14 subunit of the hetero-oligomeric complex involved in homologous recombination, RPA32 subunit of the hetero-oligomeric complex involved in homologous recombination, Replication factor A, ...
Authors:Legrand, P, Madru, C, Sauguet, L.
Deposit date:2022-07-01
Release date:2023-05-03
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:DNA-binding mechanism and evolution of replication protein A.
Nat Commun, 14, 2023
8AAS
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BU of 8aas by Molmil
Crystal structure of the Pyrococcus abyssi RPA trimerization core bound to poly-dT20 ssDNA
Descriptor: CALCIUM ION, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), RPA14 subunit of the hetero-oligomeric complex involved in homologous recombination, ...
Authors:Madru, C, Legrand, P, Sauguet, L.
Deposit date:2022-07-01
Release date:2023-05-03
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:DNA-binding mechanism and evolution of replication protein A.
Nat Commun, 14, 2023
8AA9
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BU of 8aa9 by Molmil
Crystal structure of the Rpa1 AROD-OB-1 domains
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Replication factor A
Authors:Madru, C, Legrand, P, Sauguet, L.
Deposit date:2022-06-30
Release date:2023-05-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:DNA-binding mechanism and evolution of replication protein A.
Nat Commun, 14, 2023
6EKT
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BU of 6ekt by Molmil
Structure of P47 from Clostridium botulinum A2
Descriptor: p-47 protein
Authors:Berntsson, R.P, Stenmark, P.
Deposit date:2017-09-27
Release date:2017-10-25
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structures of OrfX2 and P47 from a Botulinum neurotoxin OrfX-type gene cluster.
FEBS Lett., 591, 2017
6EKV
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BU of 6ekv by Molmil
Structure of OrfX2 from Clostridium botulinum A2
Descriptor: SULFATE ION, Toxin complex component ORF-X2
Authors:Gustafsson, R, Berntsson, R.P, Stenmark, P.
Deposit date:2017-09-27
Release date:2017-10-25
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of OrfX2 and P47 from a Botulinum neurotoxin OrfX-type gene cluster.
FEBS Lett., 591, 2017

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