Author results

1HSA
  • Download 1hsa
  • View 1hsa
Molmil generated image of 1hsa
THE THREE-DIMENSIONAL STRUCTURE OF HLA-B27 AT 2.1 ANGSTROMS RESOLUTION SUGGESTS A GENERAL MECHANISM FOR TIGHT PEPTIDE BINDING TO MHC
Descriptor:CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-B*2705), BETA 2-MICROGLOBULIN, MODEL PEPTIDE SEQUENCE - ARAAAAAAA
Authors:Madden, D.R., Gorga, J.C., Strominger, J.L., Wiley, D.C.
Deposit date:1992-08-11
Release date:1992-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The three-dimensional structure of HLA-B27 at 2.1 A resolution suggests a general mechanism for tight peptide binding to MHC.
Cell(Cambridge,Mass.), 70, 1992
1HHG
  • Download 1hhg
  • View 1hhg
Molmil generated image of 1hhg
THE ANTIGENIC IDENTITY OF PEPTIDE(SLASH)MHC COMPLEXES: A COMPARISON OF THE CONFORMATION OF FIVE PEPTIDES PRESENTED BY HLA-A2
Descriptor:CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A*0201) (ALPHA CHAIN), BETA 2-MICROGLOBULIN, HIV-1 GP120 ENVELOPE PROTEIN (RESIDUES 195-207)
Authors:Madden, D.R., Garboczi, D.N., Wiley, D.C.
Deposit date:1993-06-30
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The antigenic identity of peptide-MHC complexes: a comparison of the conformations of five viral peptides presented by HLA-A2.
Cell(Cambridge,Mass.), 75, 1993
1HHH
  • Download 1hhh
  • View 1hhh
Molmil generated image of 1hhh
THE ANTIGENIC IDENTITY OF PEPTIDE(SLASH)MHC COMPLEXES: A COMPARISON OF THE CONFORMATION OF FIVE PEPTIDES PRESENTED BY HLA-A2
Descriptor:CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A*0201) (ALPHA CHAIN), BETA 2-MICROGLOBULIN, HEPATITIS B NUCLEOCAPSID PROTEIN (RESIDUES 18-27)
Authors:Madden, D.R., Garboczi, D.N., Wiley, D.C.
Deposit date:1993-06-30
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The antigenic identity of peptide-MHC complexes: a comparison of the conformations of five viral peptides presented by HLA-A2.
Cell(Cambridge,Mass.), 75, 1993
1HHI
  • Download 1hhi
  • View 1hhi
Molmil generated image of 1hhi
THE ANTIGENIC IDENTITY OF PEPTIDE(SLASH)MHC COMPLEXES: A COMPARISON OF THE CONFORMATION OF FIVE PEPTIDES PRESENTED BY HLA-A2
Descriptor:CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A*0201) (ALPHA CHAIN), BETA 2-MICROGLOBULIN, INFLUENZA A MATRIX PROTEIN M1 (RESIDUES 58-66)
Authors:Madden, D.R., Garboczi, D.N., Wiley, D.C.
Deposit date:1993-06-30
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The antigenic identity of peptide-MHC complexes: a comparison of the conformations of five viral peptides presented by HLA-A2.
Cell(Cambridge,Mass.), 75, 1993
1HHJ
  • Download 1hhj
  • View 1hhj
Molmil generated image of 1hhj
THE ANTIGENIC IDENTITY OF PEPTIDE(SLASH)MHC COMPLEXES: A COMPARISON OF THE CONFORMATION OF FIVE PEPTIDES PRESENTED BY HLA-A2
Descriptor:CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A*0201) (ALPHA CHAIN), BETA 2-MICROGLOBULIN, HIV-1 REVERSE TRANSCRIPTASE (RESIDUES 309-317)
Authors:Madden, D.R., Garboczi, D.N., Wiley, D.C.
Deposit date:1993-06-30
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The antigenic identity of peptide-MHC complexes: a comparison of the conformations of five viral peptides presented by HLA-A2.
Cell(Cambridge,Mass.), 75, 1993
1HHK
  • Download 1hhk
  • View 1hhk
Molmil generated image of 1hhk
THE ANTIGENIC IDENTITY OF PEPTIDE(SLASH)MHC COMPLEXES: A COMPARISON OF THE CONFORMATION OF FIVE PEPTIDES PRESENTED BY HLA-A2
Descriptor:CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A*0201) (ALPHA CHAIN), BETA 2-MICROGLOBULIN, NONAMERIC PEPTIDE FROM HTLV-1 TAX PROTEIN (RESIDUES 11-19)
Authors:Madden, D.R., Garboczi, D.N., Wiley, D.C.
Deposit date:1993-06-30
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The antigenic identity of peptide-MHC complexes: a comparison of the conformations of five viral peptides presented by HLA-A2.
Cell(Cambridge,Mass.), 75, 1993
3KD2
  • Download 3kd2
  • View 3kd2
Molmil generated image of 3kd2
CRYSTAL STRUCTURE OF THE CFTR INHIBITORY FACTOR CIF
Descriptor:CFTR inhibitory factor (Cif)
Authors:Bahl, C.D., Madden, D.R.
Deposit date:2009-10-22
Release date:2010-01-26
Last modified:2011-10-12
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the cystic fibrosis transmembrane conductance regulator inhibitory factor Cif reveals novel active-site features of an epoxide hydrolase virulence factor.
J.Bacteriol., 192, 2010
1P0Z
  • Download 1p0z
  • View 1p0z
Molmil generated image of 1p0z
SENSOR KINASE CITA BINDING DOMAIN
Descriptor:Sensor kinase citA, CITRATE ANION, SODIUM ION, ...
Authors:Reinelt, S., Hofmann, E., Gerharz, T., Bott, M., Madden, D.R.
Deposit date:2003-04-11
Release date:2003-08-19
Last modified:2014-09-10
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The structure of the periplasmic ligand-binding domain of the sensor kinase CitA reveals the first extracellular PAS domain.
J.Biol.Chem., 278, 2003
2J80
  • Download 2j80
  • View 2j80
Molmil generated image of 2j80
STRUCTURE OF CITRATE-BOUND PERIPLASMIC DOMAIN OF SENSOR HISTIDINE KINASE CITA
Descriptor:SENSOR KINASE CITA, CITRATE ANION, SODIUM ION, ...
Authors:Sevvana, M., Vijayan, V., Zweckstetter, M., Reinelt, S., Madden, D.R., Sheldrick, G.M., Bott, M., Griesinger, C., Becker, S.
Deposit date:2006-10-18
Release date:2007-10-23
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A Ligand-Induced Switch in the Periplasmic Domain of Sensor Histidine Kinase Cita.
J.Mol.Biol., 377, 2008
2LOB
  • Download 2lob
  • View 2lob
Molmil generated image of 2lob
PDZ DOMAIN OF CAL (CYSTIC FIBROSIS TRANSMEMBRANE REGULATOR-ASSOCIATED LIGAND)
Descriptor:Golgi-associated PDZ and coiled-coil motif-containing protein, Cystic fibrosis transmembrane conductance regulator
Authors:Piserchio, A., Fellows, A., Madden, D.R., Mierke, D.F.
Deposit date:2012-01-20
Release date:2012-06-13
Method:SOLUTION NMR
Cite:Association of the cystic fibrosis transmembrane regulator with CAL: structural features and molecular dynamics.
Biochemistry, 44, 2005
2V9A
  • Download 2v9a
  • View 2v9a
Molmil generated image of 2v9a
STRUCTURE OF CITRATE-FREE PERIPLASMIC DOMAIN OF SENSOR HISTIDINE KINASE CITA
Descriptor:SENSOR KINASE CITA
Authors:Sevvana, M., Vijayan, V., Zweckstetter, M., Reinelt, S., Madden, D.R., Sheldrick, G.M., Bott, M., Griesinger, C., Becker, S.
Deposit date:2007-08-23
Release date:2008-03-25
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:A Ligand-Induced Switch in the Periplasmic Domain of Sensor Histidine Kinase Cita.
J.Mol.Biol., 377, 2008
3EN3
  • Download 3en3
  • View 3en3
Molmil generated image of 3en3
CRYSTAL STRUCTURE OF THE GLUR4 LIGAND-BINDING DOMAIN IN COMPLEX WITH KAINATE
Descriptor:Glutamate receptor 4,Glutamate receptor, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE
Authors:Gill, A., Madden, D.R.
Deposit date:2008-09-25
Release date:2009-05-19
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Correlating AMPA receptor activation and cleft closure across subunits: crystal structures of the GluR4 ligand-binding domain in complex with full and partial agonists
Biochemistry, 47, 2008
3EPE
  • Download 3epe
  • View 3epe
Molmil generated image of 3epe
CRYSTAL STRUCTURE OF THE GLUR4 LIGAND-BINDING DOMAIN IN COMPLEX WITH GLUTAMATE
Descriptor:Glutamate receptor 4,Glutamate receptor, GLUTAMIC ACID
Authors:Gill, A., Madden, D.R.
Deposit date:2008-09-29
Release date:2009-05-19
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Correlating AMPA receptor activation and cleft closure across subunits: crystal structures of the GluR4 ligand-binding domain in complex with full and partial agonists
Biochemistry, 47, 2008
3KDA
  • Download 3kda
  • View 3kda
Molmil generated image of 3kda
CRYSTAL STRUCTURE OF THE CFTR INHIBITORY FACTOR CIF WITH THE H269A MUTATION
Descriptor:CFTR inhibitory factor (Cif)
Authors:Bahl, C.D., Madden, D.R.
Deposit date:2009-10-22
Release date:2010-01-26
Last modified:2011-10-12
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of the cystic fibrosis transmembrane conductance regulator inhibitory factor Cif reveals novel active-site features of an epoxide hydrolase virulence factor.
J.Bacteriol., 192, 2010
3KEI
  • Download 3kei
  • View 3kei
Molmil generated image of 3kei
CRYSTAL STRUCTURE OF THE GLUA4 LIGAND-BINDING DOMAIN L651V MUTANT IN COMPLEX WITH GLUTAMATE
Descriptor:Glutamate receptor 4, GLUTAMIC ACID
Authors:Gill, A., Madden, D.R.
Deposit date:2009-10-26
Release date:2010-02-09
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Enhanced efficacy without further cleft closure: reevaluating twist as a source of agonist efficacy in AMPA receptors.
J.Neurosci., 30, 2010
3KFM
  • Download 3kfm
  • View 3kfm
Molmil generated image of 3kfm
CRYSTAL STRUCTURE OF THE GLUA4 LIGAND-BINDING DOMAIN L651V MUTANT IN COMPLEX WITH KAINATE
Descriptor:Glutamate receptor 4, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE
Authors:Gill, A., Madden, D.R.
Deposit date:2009-10-27
Release date:2010-02-09
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Enhanced efficacy without further cleft closure: reevaluating twist as a source of agonist efficacy in AMPA receptors.
J.Neurosci., 30, 2010
3PI6
  • Download 3pi6
  • View 3pi6
Molmil generated image of 3pi6
CRYSTAL STRUCTURE OF THE CFTR INHIBITORY FACTOR CIF WITH THE H177Y MUTATION
Descriptor:hydrolase
Authors:Bahl, C.D., Madden, D.R.
Deposit date:2010-11-05
Release date:2011-09-21
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Pseudomonas aeruginosa Cif defines a distinct class of alpha/beta epoxide hydrolases utilizing a His/Tyr ring-opening pair.
Protein Pept.Lett., 19, 2012
3SFJ
  • Download 3sfj
  • View 3sfj
Molmil generated image of 3sfj
CRYSTAL STRUCTURE OF TAX-INTERACTING PROTEIN-1 (TIP-1) PDZ DOMAIN BOUND TO ICAL36 INHIBITOR PEPTIDE
Descriptor:Tax1-binding protein 3, decameric peptide iCAL36
Authors:Amacher, J.F., Madden, D.R.
Deposit date:2011-06-13
Release date:2012-12-12
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:A CAL Inhibitor with Single-PDZ Specificity Rescues deltaF508-CFTR
To be Published
4DLN
  • Download 4dln
  • View 4dln
Molmil generated image of 4dln
CRYSTAL STRUCTURE OF THE CFTR INHIBITORY FACTOR CIF WITH THE D129S MUTATION
Descriptor:Putative hydrolase
Authors:Bahl, C.D., Amacher, J.F., Madden, D.R.
Deposit date:2012-02-06
Release date:2013-08-07
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Inhibiting an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa Protects CFTR.
Angew.Chem.Int.Ed.Engl., 54, 2015
4DM7
  • Download 4dm7
  • View 4dm7
Molmil generated image of 4dm7
CRYSTAL STRUCTURE OF THE CFTR INHIBITORY FACTOR CIF WITH THE E153D MUTATION
Descriptor:Putative hydrolase
Authors:Bahl, C.D., Madden, D.R.
Deposit date:2012-02-07
Release date:2013-08-07
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Inhibiting an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa Protects CFTR.
Angew.Chem.Int.Ed.Engl., 54, 2015
4DMC
  • Download 4dmc
  • View 4dmc
Molmil generated image of 4dmc
CRYSTAL STRUCTURE OF THE CFTR INHIBITORY FACTOR CIF WITH THE E153Q MUTATION
Descriptor:Putative hydrolase
Authors:Bahl, C.D., Madden, D.R.
Deposit date:2012-02-07
Release date:2013-08-07
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Visualizing the Mechanism of Epoxide Hydrolysis by the Bacterial Virulence Enzyme Cif.
Biochemistry, 55, 2016
4DMF
  • Download 4dmf
  • View 4dmf
Molmil generated image of 4dmf
CRYSTAL STRUCTURE OF THE CFTR INHIBITORY FACTOR CIF WITH THE H177A MUTATION
Descriptor:Putative hydrolase
Authors:Bahl, C.D., Madden, D.R.
Deposit date:2012-02-07
Release date:2013-08-07
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Inhibiting an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa Protects CFTR.
Angew.Chem.Int.Ed.Engl., 54, 2015
4DMH
  • Download 4dmh
  • View 4dmh
Molmil generated image of 4dmh
CRYSTAL STRUCTURE OF THE CFTR INHIBITORY FACTOR CIF WITH THE H207A MUTATION
Descriptor:Putative hydrolase, GLYCEROL
Authors:Bahl, C.D., Madden, D.R.
Deposit date:2012-02-07
Release date:2013-08-07
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Inhibiting an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa Protects CFTR.
Angew.Chem.Int.Ed.Engl., 54, 2015
4DMK
  • Download 4dmk
  • View 4dmk
Molmil generated image of 4dmk
CRYSTAL STRUCTURE OF THE CFTR INHIBITORY FACTOR CIF WITH THE Y239F MUTATION
Descriptor:Putative hydrolase, GLYCEROL
Authors:Bahl, C.D., Madden, D.R.
Deposit date:2012-02-07
Release date:2013-08-07
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Inhibiting an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa Protects CFTR.
Angew.Chem.Int.Ed.Engl., 54, 2015
4DNF
  • Download 4dnf
  • View 4dnf
Molmil generated image of 4dnf
CRYSTAL STRUCTURE OF THE CFTR INHIBITORY FACTOR CIF WITH THE E153Q MUTATION ADDUCTED WITH THE EPIBROMOHYDRIN HYDROLYSIS INTERMEDIATE
Descriptor:Putative hydrolase, (2S)-1-bromopropan-2-ol
Authors:Bahl, C.D., Madden, D.R.
Deposit date:2012-02-08
Release date:2013-08-07
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Visualizing the Mechanism of Epoxide Hydrolysis by the Bacterial Virulence Enzyme Cif.
Biochemistry, 55, 2016