Author results

1OB0
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KINETIC STABILIZATION OF BACILLUS LICHENIFORMIS ALPHA-AMYLASE THROUGH INTRODUCTION OF HYDROPHOBIC RESIDUES AT THE SURFACE
Descriptor:ALPHA-AMYLASE, CALCIUM ION, SODIUM ION
Authors:Machius, M., Declerck, N., Huber, R., Wiegand, G.
Deposit date:2003-01-21
Release date:2003-01-30
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Kinetic Stabilization of Bacillus Licheniformis Alpha-Amylase Through Introduction of Hydrophobic Residues at the Surface
J.Biol.Chem., 278, 2003
1WCI
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REACTIVITY MODULATION OF HUMAN BRANCHED-CHAIN ALPHA-KETOACID DEHYDROGENASE BY AN INTERNAL MOLECULAR SWITCH
Descriptor:2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, CHLORIDE ION, ...
Authors:Machius, M., Wynn, R.M., Chuang, J.L., Tomchick, D.R., Brautigam, C.A., Chuang, D.T.
Deposit date:2004-11-16
Release date:2006-02-16
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:A Versatile Conformational Switch Regulates Reactivity in Human Branched-Chain Alpha-Ketoacid Dehydrogenase.
Structure, 14, 2006
2BEU
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REACTIVITY MODULATION OF HUMAN BRANCHED-CHAIN ALPHA-KETOACID DEHYDROGENASE BY AN INTERNAL MOLECULAR SWITCH
Descriptor:2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, PEPTIDE ALA-TYR-ARG, ...
Authors:Machius, M., Wynn, R.M., Chuang, J.L., Tomchick, D.R., Brautigam, C.A., Chuang, D.T.
Deposit date:2004-11-30
Release date:2006-02-16
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:A Versatile Conformational Switch Regulates Reactivity in Human Branched-Chain Alpha-Ketoacid Dehydrogenase.
Structure, 14, 2006
2BEV
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REACTIVITY MODULATION OF HUMAN BRANCHED-CHAIN ALPHA-KETOACID DEHYDROGENASE BY AN INTERNAL MOLECULAR SWITCH
Descriptor:2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, PEPTIDE ALA-TYR-ARG, ...
Authors:Machius, M., Wynn, R.M., Chuang, J.L., Tomchick, D.R., Brautigam, C.A., Chuang, D.T.
Deposit date:2004-11-30
Release date:2006-02-16
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A Versatile Conformational Switch Regulates Reactivity in Human Branched-Chain Alpha-Ketoacid Dehydrogenase.
Structure, 14, 2006
2BEW
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REACTIVITY MODULATION OF HUMAN BRANCHED-CHAIN ALPHA-KETOACID DEHYDROGENASE BY AN INTERNAL MOLECULAR SWITCH
Descriptor:2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, PEPTIDE ALA-TYR-ARG, ...
Authors:Machius, M., Wynn, R.M., Chuang, J.L., Tomchick, D.R., Brautigam, C.A., Chuang, D.T.
Deposit date:2004-11-30
Release date:2006-02-16
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:A Versatile Conformational Switch Regulates Reactivity in Human Branched-Chain Alpha-Ketoacid Dehydrogenase.
Structure, 14, 2006
2BFB
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REACTIVITY MODULATION OF HUMAN BRANCHED-CHAIN ALPHA-KETOACID DEHYDROGENASE BY AN INTERNAL MOLECULAR SWITCH
Descriptor:2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, POTASSIUM ION, ...
Authors:Machius, M., Wynn, R.M., Chuang, J.L., Tomchick, D.R., Brautigam, C.A., Chuang, D.T.
Deposit date:2004-12-06
Release date:2006-02-16
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:A Versatile Conformational Switch Regulates Reactivity in Human Branched-Chain Alpha-Ketoacid Dehydrogenase.
Structure, 14, 2006
2BFC
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REACTIVITY MODULATION OF HUMAN BRANCHED-CHAIN ALPHA-KETOACID DEHYDROGENASE BY AN INTERNAL MOLECULAR SWITCH
Descriptor:2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, POTASSIUM ION, ...
Authors:Machius, M., Wynn, R.M., Chuang, J.L., Tomchick, D.R., Brautigam, C.A., Chuang, D.T.
Deposit date:2004-12-06
Release date:2006-02-16
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:A Versatile Conformational Switch Regulates Reactivity in Human Branched-Chain Alpha-Ketoacid Dehydrogenase.
Structure, 14, 2006
2BFD
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REACTIVITY MODULATION OF HUMAN BRANCHED-CHAIN ALPHA-KETOACID DEHYDROGENASE BY AN INTERNAL MOLECULAR SWITCH
Descriptor:2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, POTASSIUM ION, ...
Authors:Machius, M., Wynn, R.M., Chuang, J.L., Tomchick, D.R., Brautigam, C.A., Chuang, D.T.
Deposit date:2004-12-06
Release date:2006-02-16
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:A Versatile Conformational Switch Regulates Reactivity in Human Branched-Chain Alpha-Ketoacid Dehydrogenase.
Structure, 14, 2006
2BFE
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REACTIVITY MODULATION OF HUMAN BRANCHED-CHAIN ALPHA-KETOACID DEHYDROGENASE BY AN INTERNAL MOLECULAR SWITCH
Descriptor:2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, POTASSIUM ION, ...
Authors:Machius, M., Wynn, R.M., Chuang, J.L., Tomchick, D.R., Brautigam, C.A., Chuang, D.T.
Deposit date:2004-12-06
Release date:2006-02-16
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:A Versatile Conformational Switch Regulates Reactivity in Human Branched-Chain Alpha-Ketoacid Dehydrogenase.
Structure, 14, 2006
2BFF
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REACTIVITY MODULATION OF HUMAN BRANCHED-CHAIN ALPHA-KETOACID DEHYDROGENASE BY AN INTERNAL MOLECULAR SWITCH
Descriptor:2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, 2-{3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-4-METHYL-2-OXO-2,3-DIHYDRO-1,3-THIAZOL-5-YL}ETHYL TRIHYDROGEN DIPHOSPHATE, ...
Authors:Machius, M., Wynn, R.M., Chuang, J.L., Tomchick, D.R., Brautigam, C.A., Chuang, D.T.
Deposit date:2004-12-06
Release date:2006-02-16
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:A Versatile Conformational Switch Regulates Reactivity in Human Branched-Chain Alpha-Ketoacid Dehydrogenase.
Structure, 14, 2006
1BLI
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BACILLUS LICHENIFORMIS ALPHA-AMYLASE
Descriptor:ALPHA-AMYLASE, CALCIUM ION, SODIUM ION
Authors:Machius, M., Declerck, N., Huber, R., Wiegand, G.
Deposit date:1998-01-07
Release date:1999-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Activation of Bacillus licheniformis alpha-amylase through a disorder-->order transition of the substrate-binding site mediated by a calcium-sodium-calcium metal triad.
Structure, 6, 1998
1C4O
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CRYSTAL STRUCTURE OF THE DNA NUCLEOTIDE EXCISION REPAIR ENZYME UVRB FROM THERMUS THERMOPHILUS
Descriptor:DNA NUCLEOTIDE EXCISION REPAIR ENZYME UVRB, B-OCTYLGLUCOSIDE, SULFATE ION
Authors:Machius, M., Henry, L., Palnitkar, M., Deisenhofer, J.
Deposit date:1999-09-14
Release date:2000-07-26
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of the DNA nucleotide excision repair enzyme UvrB from Thermus thermophilus.
Proc.Natl.Acad.Sci.USA, 96, 1999
1PIF
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PIG ALPHA-AMYLASE
Descriptor:ALPHA-AMYLASE, CALCIUM ION, CHLORIDE ION
Authors:Machius, M., Vertesy, L., Huber, R., Wiegand, G.
Deposit date:1996-06-15
Release date:1996-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Carbohydrate and protein-based inhibitors of porcine pancreatic alpha-amylase: structure analysis and comparison of their binding characteristics.
J.Mol.Biol., 260, 1996
1PIG
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PIG PANCREATIC ALPHA-AMYLASE COMPLEXED WITH THE OLIGOSACCHARIDE V-1532
Descriptor:ALPHA-AMYLASE, 4,6-DIDEOXY-4-AMINO-ALPHA-D-GLUCOSE, ALPHA-D-GLUCOSE, ...
Authors:Machius, M., Vertesy, L., Huber, R., Wiegand, G.
Deposit date:1996-06-15
Release date:1996-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Carbohydrate and protein-based inhibitors of porcine pancreatic alpha-amylase: structure analysis and comparison of their binding characteristics.
J.Mol.Biol., 260, 1996
1BPL
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GLYCOSYLTRANSFERASE
Descriptor:ALPHA-1,4-GLUCAN-4-GLUCANOHYDROLASE
Authors:Machius, M., Wiegand, G., Huber, R.
Deposit date:1995-07-13
Release date:1996-08-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of calcium-depleted Bacillus licheniformis alpha-amylase at 2.2 A resolution.
J.Mol.Biol., 246, 1995
1GJV
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BRANCHED-CHAIN ALPHA-KETOACID DEHYDROGENASE KINASE (BCK) COMPLXED WITH ATP-GAMMA-S
Descriptor:[3-METHYL-2-OXOBUTANOATE DEHYDROGENASE [LIPOAMIDE]] KINASE, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Machius, M., Chuang, J.L., Wynn, M.R., Tomchick, D.R., Chuang, D.T.
Deposit date:2001-08-03
Release date:2001-10-11
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of Rat Bckd Kinase: Nucleotide-Induced Domain Communication in a Mitochondrial Protein Kinase.
Proc.Natl.Acad.Sci.USA, 98, 2001
1GKX
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BRANCHED-CHAIN ALPHA-KETOACID DEHYDROGENASE KINASE (BCK)
Descriptor:[3-METHYL-2-OXOBUTANOATE DEHYDROGENASE [LIPOAMIDE]] KINASE, CHLORIDE ION
Authors:Machius, M., Chuang, J.L., Wynn, R.M., Tomchick, D.R., Chuang, D.T.
Deposit date:2001-08-21
Release date:2001-10-11
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of Rat Bckd Kinase: Nucleotide-Induced Domain Communication in a Mitochondrial Protein Kinase.
Proc.Natl.Acad.Sci.USA, 98, 2001
1GKZ
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BRANCHED-CHAIN ALPHA-KETOACID DEHYDROGENASE KINASE (BCK) COMPLXED WITH ADP
Descriptor:[3-METHYL-2-OXOBUTANOATE DEHYDROGENASE [LIPOAMIDE]] KINASE, MAGNESIUM ION, POTASSIUM ION, ...
Authors:Machius, M., Chuang, J.L., Wynn, R.M., Tomchick, D.R., Chuang, D.T.
Deposit date:2001-08-22
Release date:2001-10-11
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of Rat Bckd Kinase: Nucleotide-Induced Domain Communication in a Mitochondrial Protein Kinase.
Proc.Natl.Acad.Sci.USA, 98, 2001
1H5B
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T CELL RECEPTOR VALPHA11 (AV11S5) DOMAIN
Descriptor:MURINE T CELL RECEPTOR (TCR) VALPHA DOMAIN, CHLORIDE ION, GLYCEROL
Authors:Machius, M., Cianga, P., Deisenhofer, J., Sally Ward, E.
Deposit date:2001-05-21
Release date:2001-06-21
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of a T Cell Receptor Valpha11 (Av11S5) Domain: New Canonical Forms for the First and Second Complementarity Determining Regions
J.Mol.Biol., 310, 2001
2V84
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CRYSTAL STRUCTURE OF THE TP0655 (TPPOTD) LIPOPROTEIN OF TREPONEMA PALLIDUM
Descriptor:SPERMIDINE/PUTRESCINE ABC TRANSPORTER, PERIPLASMIC BINDING PROTEIN, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Machius, M., Brautigam, C.A., Tomchick, D.R., Ward, P., Otwinowski, Z., Blevine, J.S., Deka, R.K., Norgard, M.V.
Deposit date:2007-08-02
Release date:2007-09-25
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structural and Biochemical Basis for Polyamine Binding to the Tp0655 Lipoprotein of Treponema Pallidum: Putative Role for Tp0655 (Tppotd) as a Polyamine Receptor.
J.Mol.Biol., 373, 2007
2O6C
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STRUCTURE OF SELENOMETHIONYL RTP34 FROM TREPONEMA PALLIDUM
Descriptor:34 kDa membrane antigen, CHLORIDE ION, 1,2-ETHANEDIOL, ...
Authors:Machius, M., Brautigam, C.A., Deka, R.K., Tomchick, D.R., Lumpkins, S.B., Norgard, M.V.
Deposit date:2006-12-07
Release date:2006-12-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the Tp34 (TP0971) lipoprotein of treponema pallidum: implications of its metal-bound state and affinity for human lactoferrin.
J.Biol.Chem., 282, 2007
2O6D
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STRUCTURE OF NATIVE RTP34 FROM TREPONEMA PALLIDUM
Descriptor:34 kDa membrane antigen, ZINC ION, SULFATE ION, ...
Authors:Machius, M., Brautigam, C.A., Deka, R.K., Tomchick, D.R., Lumpkins, S.B., Norgard, M.V.
Deposit date:2006-12-07
Release date:2006-12-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Crystal structure of the Tp34 (TP0971) lipoprotein of treponema pallidum: implications of its metal-bound state and affinity for human lactoferrin.
J.Biol.Chem., 282, 2007
2O6E
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STRUCTURE OF NATIVE RTP34 FROM TREPONEMA PALLIDUM FROM ZINC-SOAKED CRYSTALS
Descriptor:34 kDa membrane antigen, ZINC ION, SULFATE ION, ...
Authors:Machius, M., Brautigam, C.A., Deka, R.K., Tomchick, D.R., Lumpkins, S.B., Norgard, M.V.
Deposit date:2006-12-07
Release date:2006-12-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the Tp34 (TP0971) lipoprotein of treponema pallidum: implications of its metal-bound state and affinity for human lactoferrin.
J.Biol.Chem., 282, 2007
2O6F
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STRUCTURE OF METAL- FREE RTP34 FROM TREPONEMA PALLIDUM
Descriptor:34 kDa membrane antigen, SULFATE ION, CHLORIDE ION, ...
Authors:Machius, M., Brautigam, C.A., Deka, R.K., Tomchick, D.R., Lumpkins, S.B., Norgard, M.V.
Deposit date:2006-12-07
Release date:2006-12-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Crystal structure of the Tp34 (TP0971) lipoprotein of treponema pallidum: implications of its metal-bound state and affinity for human lactoferrin.
J.Biol.Chem., 282, 2007
5V5W
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MOLECULAR MECHANISM OF MDGA1: REGULATION OF NEUROLIGIN 2:NEUREXIN TRANS-SYNAPTIC BRIDGES
Descriptor:MAM domain-containing glycosylphosphatidylinositol anchor protein 1, SULFATE ION
Authors:Machius, M., Gangwar, S.P., Rudenko, G.
Deposit date:2017-03-15
Release date:2017-07-05
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.718 Å)
Cite:Molecular Mechanism of MDGA1: Regulation of Neuroligin 2:Neurexin Trans-synaptic Bridges.
Neuron, 94, 2017