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1GLU
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BU of 1glu by Molmil
CRYSTALLOGRAPHIC ANALYSIS OF THE INTERACTION OF THE GLUCOCORTICOID RECEPTOR WITH DNA
Descriptor: DNA (5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*TP*CP*GP*AP*TP*GP*TP*TP*C P*TP*G)-3'), PROTEIN (GLUCOCORTICOID RECEPTOR), ZINC ION
Authors:Luisi, B.F, Xu, W.X, Otwinowski, Z, Freedman, L.P, Yamamoto, K.R, Sigler, P.B.
Deposit date:1992-08-30
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA.
Nature, 352, 1991
1R4R
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BU of 1r4r by Molmil
Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA
Descriptor: 5'-D(*CP*TP*GP*AP*GP*AP*AP*CP*AP*TP*CP*AP*TP*GP*TP*TP*CP*TP*G)-3', 5'-D(*TP*CP*AP*GP*AP*AP*CP*AP*TP*GP*AP*TP*GP*TP*TP*CP*TP*CP*A)-3', Glucocorticoid receptor, ...
Authors:Luisi, B.F, Xu, W.X, Otwinowski, Z, Freedman, L.P, Yamamoto, K.R, Sigler, P.B.
Deposit date:2003-10-07
Release date:2003-10-28
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystallographic Analysis of the Interaction of the Glucocorticoid Receptor with DNA
Nature, 352, 1991
1R4O
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BU of 1r4o by Molmil
Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA
Descriptor: 5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*TP*CP*GP*AP*TP*GP*TP*TP*CP*TP*G)-3', Glucocorticoid receptor, ZINC ION
Authors:Luisi, B.F, Xu, W.X, Otwinowski, Z, Freedman, L.P, Yamamoto, K.R, Sigler, P.B.
Deposit date:2003-10-07
Release date:2003-10-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystallographic Analysis of the Interaction of The Glucocorticoid Receptor with DNA
Nature, 352, 1991
7PCR
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BU of 7pcr by Molmil
Helicobacter pylori RNase J
Descriptor: Ribonuclease J
Authors:Luisi, B.F, Pei, X.Y.
Deposit date:2021-08-03
Release date:2022-05-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Acetylation regulates the oligomerization state and activity of RNase J, the Helicobacter pylori major ribonuclease.
Nat Commun, 14, 2023
5NQB
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BU of 5nqb by Molmil
Rabbit Muscle L-lactate dehydrogenase in complex with malonate
Descriptor: L-lactate dehydrogenase A chain, MALONATE ION
Authors:Luisi, B.F, Olin-Sandoval, V.
Deposit date:2017-04-19
Release date:2017-05-03
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:The self-inhibitory nature of metabolic networks and its alleviation through compartmentalization.
Nat Commun, 8, 2017
5NQQ
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BU of 5nqq by Molmil
Rabbit Muscle L-lactate dehydrogenase in complex with NADH and oxaloacetate
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, L-lactate dehydrogenase A chain, OXALOACETATE ION, ...
Authors:Luisi, B.F, Olin-Sandoval, V.
Deposit date:2017-04-20
Release date:2017-06-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.872 Å)
Cite:The self-inhibitory nature of metabolic networks and its alleviation through compartmentalization.
Nat Commun, 8, 2017
8B0J
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BU of 8b0j by Molmil
CryoEM structure of bacterial RNaseE.RapZ.GlmZ complex central to the control of cell envelope biogenesis
Descriptor: GlmZ small RNA, RNase adapter protein RapZ, Ribonuclease E
Authors:Islam, M.S, Hardwick, H.W, Chirgadze, D.Y, Luisi, B.F.
Deposit date:2022-09-07
Release date:2022-10-05
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.99 Å)
Cite:Structure of a bacterial ribonucleoprotein complex central to the control of cell envelope biogenesis.
Embo J., 42, 2023
8B0I
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BU of 8b0i by Molmil
CryoEM structure of bacterial RapZ.GlmZ complex central to the control of cell envelope biogenesis
Descriptor: GlmZ small regulatory RNA, RNase adapter protein RapZ
Authors:Islam, M.S, Hardwick, H.W, Chirgadze, D.Y, Luisi, B.F.
Deposit date:2022-09-07
Release date:2022-10-05
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (4.28 Å)
Cite:Structure of a bacterial ribonucleoprotein complex central to the control of cell envelope biogenesis.
Embo J., 42, 2023
4V2S
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BU of 4v2s by Molmil
Crystal structure of Hfq in complex with the sRNA RydC
Descriptor: RNA-BINDING PROTEIN HFQ, RYDC
Authors:Dimastrogiovanni, D, Frohlich, K.S, Bruce, H.A, Bandyra, K.J, Hohensee, S, Vogel, J, Luisi, B.F.
Deposit date:2014-10-14
Release date:2015-01-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.48 Å)
Cite:Recognition of the small regulatory RNA RydC by the bacterial Hfq protein.
Elife, 3, 2014
1TRO
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BU of 1tro by Molmil
CRYSTAL STRUCTURE OF TRP REPRESSOR OPERATOR COMPLEX AT ATOMIC RESOLUTION
Descriptor: DNA (5'-D(*TP*GP*TP*AP*CP*TP*AP*GP*TP*TP*AP*AP*CP*TP*AP*GP*T P*AP*C)-3'), PROTEIN (TRP REPRESSOR), TRYPTOPHAN
Authors:Otwinowski, Z, Schevitz, R.W, Zhang, R.-G, Lawson, C.L, Joachimiak, A, Marmorstein, R, Luisi, B.F, Sigler, P.B.
Deposit date:1992-08-30
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of trp repressor/operator complex at atomic resolution.
Nature, 335, 1988
9QH3
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BU of 9qh3 by Molmil
Pseudomonas aeruginosa polynucleotide phosphorylase in complex with recognition site of RNase E
Descriptor: ADENOSINE-5'-MONOPHOSPHATE, Polyribonucleotide nucleotidyltransferase, Ribonuclease E
Authors:Paris, G, Luisi, B.F.
Deposit date:2025-03-14
Release date:2025-05-14
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Pseudomonas aeruginosa polynucleotide phosphorylase in complex with recognition site of RNase E
To Be Published
9QH0
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BU of 9qh0 by Molmil
Escherichia coli polynucleotide phosphorylase in complex with recognition site of RNase E
Descriptor: Polyribonucleotide nucleotidyltransferase, Ribonuclease E
Authors:Paris, G, Luisi, B.F.
Deposit date:2025-03-14
Release date:2025-04-23
Method:ELECTRON MICROSCOPY (2.52 Å)
Cite:Escherichia coli polynucleotide phosphorylase in complex with recognition site of RNase E
To Be Published
1W85
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BU of 1w85 by Molmil
The crystal structure of pyruvate dehydrogenase E1 bound to the peripheral subunit binding domain of E2
Descriptor: DI(HYDROXYETHYL)ETHER, DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE, MAGNESIUM ION, ...
Authors:Frank, R.A.W, Pratap, J.V, Pei, X.Y, Perham, R.N, Luisi, B.F.
Deposit date:2004-09-16
Release date:2004-11-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:A molecular switch and proton wire synchronize the active sites in thiamine enzymes.
Science, 306, 2004
1W88
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BU of 1w88 by Molmil
The crystal structure of pyruvate dehydrogenase E1(D180N,E183Q) bound to the peripheral subunit binding domain of E2
Descriptor: DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE, MAGNESIUM ION, PYRUVATE DEHYDROGENASE E1 COMPONENT, ...
Authors:Frank, R.A.W, Pratap, J.V, Pei, X.Y, Perham, R.N, Luisi, B.F.
Deposit date:2004-09-16
Release date:2004-11-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A Molecular Switch and Proton-Wire Synchronize the Active Sites in Thiamine-Dependent Enzymes
Science, 306, 2004
6G63
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BU of 6g63 by Molmil
RNase E in complex with sRNA RrpA
Descriptor: RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3'), Ribonuclease E, URIDINE-5'-MONOPHOSPHATE, ...
Authors:Bandyra, K.B, Luisi, B.F.
Deposit date:2018-03-31
Release date:2018-10-03
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.95 Å)
Cite:Substrate Recognition and Autoinhibition in the Central Ribonuclease RNase E.
Mol. Cell, 72, 2018
6GWK
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BU of 6gwk by Molmil
The crystal structure of Hfq from Caulobacter crescentus
Descriptor: RNA-binding protein Hfq
Authors:Santiago-Frangos, A, Frohlich, K.S, Jeliazkov, J.R, Gray, J.R, Luisi, B.F, Woodson, S.A, Hardwick, S.W.
Deposit date:2018-06-25
Release date:2019-05-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Caulobacter crescentusHfq structure reveals a conserved mechanism of RNA annealing regulation.
Proc.Natl.Acad.Sci.USA, 116, 2019
6HCK
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BU of 6hck by Molmil
The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with dipeptide Leu-Leu
Descriptor: LEUCINE, Listeriolysin regulatory protein, SODIUM ION
Authors:Grundstrom, C, Oelker, M, Krypotou, E, Scortti, M, Luisi, B.F, Vazquez-Boland, J, Sauer-Eriksson, A.E.
Deposit date:2018-08-15
Release date:2019-02-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Control of Bacterial Virulence through the Peptide Signature of the Habitat.
Cell Rep, 26, 2019
2V07
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BU of 2v07 by Molmil
Structure of the Arabidopsis thaliana cytochrome c6A V52Q variant
Descriptor: CYTOCHROME C6, HEME C
Authors:Worrall, J.A.R, Schlarb-Ridley, B.G, Reda, T, Marcaida, M.J, Moorlen, R.J, Wastl, J, Hirst, J, Bendall, D.S, Luisi, B.F, Howe, C.J.
Deposit date:2007-05-09
Release date:2007-07-24
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Modulation of heme redox potential in the cytochrome c6 family.
J. Am. Chem. Soc., 129, 2007
2VMK
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BU of 2vmk by Molmil
Crystal Structure of E. coli RNase E Apoprotein - Catalytic Domain
Descriptor: RIBONUCLEASE E, SULFATE ION, ZINC ION
Authors:Koslover, D.J, Callaghan, A.J, Marcaida, M.J, Martick, M, Scott, W.G, Luisi, B.F.
Deposit date:2008-01-28
Release date:2008-07-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The Crystal Structure of the Escherichia Coli Rnase E Apoprotein and a Mechanism for RNA Degradation.
Structure, 16, 2008
2V08
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BU of 2v08 by Molmil
Structure of wild-type Phormidium laminosum cytochrome c6
Descriptor: CHLORIDE ION, CYTOCHROME C6, HEME C, ...
Authors:Worrall, J.A.R, Schlarb-Ridley, B.G, Reda, T, Marcaida, M.J, Moorlen, R.J, Wastl, J, Hirst, J, Bendall, D.S, Luisi, B.F, Howe, C.J.
Deposit date:2007-05-10
Release date:2007-07-24
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Modulation of heme redox potential in the cytochrome c6 family.
J. Am. Chem. Soc., 129, 2007
8CGL
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BU of 8cgl by Molmil
Cryo-EM structure of RNase J from Helicobacter pylori
Descriptor: Ribonuclease J
Authors:Lulla, A, Luisi, B.F.
Deposit date:2023-02-05
Release date:2023-12-27
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Acetylation regulates the oligomerization state and activity of RNase J, the Helicobacter pylori major ribonuclease.
Nat Commun, 14, 2023
3DV0
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BU of 3dv0 by Molmil
Snapshots of catalysis in the E1 subunit of the pyruvate dehydrogenase multi-enzyme complex
Descriptor: 2-{4-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-3-METHYLTHIOPHEN-2-YL}ETHYL TRIHYDROGEN DIPHOSPHATE, Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, MAGNESIUM ION, ...
Authors:Pei, X.Y, Titman, C.M, Frank, R.A.W, Leeper, F.J, Luisi, B.F.
Deposit date:2008-07-18
Release date:2009-01-13
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Snapshots of catalysis in the e1 subunit of the pyruvate dehydrogenase multienzyme complex
Structure, 16, 2008
3DVA
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BU of 3dva by Molmil
Snapshots of catalysis in the E1 subunit of the pyruvate dehydrogenase multi-enzyme complex
Descriptor: 2-{4-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-3-METHYLTHIOPHEN-2-YL}ETHYL TRIHYDROGEN DIPHOSPHATE, Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, MAGNESIUM ION, ...
Authors:Pei, X.Y, Titman, C.M, Frank, R.A.W, Leeper, F.J, Luisi, B.F.
Deposit date:2008-07-18
Release date:2009-01-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Snapshots of catalysis in the e1 subunit of the pyruvate dehydrogenase multienzyme complex
Structure, 16, 2008
3DUF
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BU of 3duf by Molmil
Snapshots of catalysis in the E1 subunit of the pyruvate dehydrogenase multi-enzyme complex
Descriptor: 2-{4-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-5-[(1R)-1-HYDROXYETHYL]-3-METHYL-2-THIENYL}ETHYL TRIHYDROGEN DIPHOSPHATE, Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, MAGNESIUM ION, ...
Authors:Pei, X.Y, Titman, C.M, Frank, R.A.W, Leeper, F.J, Luisi, B.F.
Deposit date:2008-07-17
Release date:2009-01-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Snapshots of catalysis in the e1 subunit of the pyruvate dehydrogenase multienzyme complex
Structure, 16, 2008
7AUA
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BU of 7aua by Molmil
Cryo-EM structure of human exostosin-like 3 (EXTL3) in complex with UDP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Exostosin-like 3, MANGANESE (II) ION, ...
Authors:Wilson, L.F.L, Dendooven, T, Hardwick, S.W, Chirgadze, D.Y, Luisi, B.F, Logan, D.T, Mani, K, Dupree, P.
Deposit date:2020-11-02
Release date:2022-05-18
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:The structure of EXTL3 helps to explain the different roles of bi-domain exostosins in heparan sulfate synthesis.
Nat Commun, 13, 2022

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